4-Aminophenol supplier | CasNO.123-30-8

Name
4-Aminophenol
EINECS 204-616-2
CAS No. 123-30-8
Article Data600
CAS DataBase
Density 1.21 g/cm³
Solubility Water: 1.5 g/100 mL (20 °C)
Melting Point 188 °C
Formula C₆H₇NO
Boiling Point 281.984 °C at 760 mmHg
Molecular Weight 109.128
Flash Point 124.34 °C
Transport Information UN 2512 6.1/PG 3
Appearance Off white granular powder
Safety 28-36/37-60-61-28A
Risk Codes 20/22-50/53-68-40
Molecular Structure
Hazard Symbols Xn,N
Synonyms Phenol,p-amino- (8CI);1-Amino-4-hydroxybenzene;4-Amino-1-hydroxybenzene;4-Hydroxy-1-aminobenzene;4-Hydroxyaniline;4-Hydroxybenzenamine;4-Hydroxyphenylamine;Activol;Azol;BASF Ursol P Base;Benzofur P;C.I. 76550;C.I. Oxidation Base 6;Certinal;Citol;Durafur Brown RB;Fouramine P;Fourrine84;Fourrine P Base;Furro P base;NSC 1545;Nako Brown R;Paranol;PelagolGrey P Base;Pelagol P Base;Renal AC;Rodinal;Tertral P Base;Unal;Ursol P;Ursol P Base;Zoba Brown P Base;p-Aminophenol;p-Hydroxyaniline;p-Hydroxyphenylamine;p-Amino phenol;4-Aminophenol, para amino phenol;4-Aminophenol;
PSA 46.25000
LogP 1.55560

Synthetic route

: 100-02-7
4-nitro-phenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With copper(I) chloride; potassium borohydride In methanol for 0.166667h; Ambient temperature;	100%
With palladium diacetate; carbon monoxide; triphenylphosphine In water; acetic acid at 56℃; under 532 Torr; for 14h;	100%
With hydrazine hydrate In ethanol at 80℃;	100%

: 62-53-3
aniline

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With dihydrogen peroxide In water at 20℃; for 1.66667h; Reagent/catalyst; UV-irradiation; Green chemistry; regioselective reaction;	100%
With dihydrogen peroxide; polymer 1-A In methanol for 0.05h; Ambient temperature;	4.9%
With dihydrogen peroxide; polymer 1-A In methanol for 0.05h; Product distribution; Kinetics; Ambient temperature; various catalysts were used;	4.9%

: 103-90-2
4-acetaminophenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With ammonium bromide; ethylenediamine at 70℃; for 5h; Reagent/catalyst; Temperature; Microwave irradiation;	100%
With ammonium bromide; ethylenediamine at 70℃; for 5h; Microwave irradiation; Inert atmosphere; neat (no solvent);	99%
With ammonium iodide; hydrazine hydrate at 50℃; for 12h; Inert atmosphere; Sealed tube;	97%

: 54840-09-4
carbamate de methyle et de N(hydroxy-4 phenyle)

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With 3-azapentane-1,5-diamine at 130℃; for 12h; Sealed tube;	99%

: 24541-43-3
4-azidophenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With hydrazine hydrate In ethanol at 20℃; chemoselective reaction;	98%
With aluminium(III) iodide In benzene for 0.166667h; Reduction; Heating;	93%
With gallium(III) triflate; potassium iodide In acetonitrile at 60℃; for 1h; Inert atmosphere; Green chemistry; chemoselective reaction;	93%

: 36309-42-9
4-(trimethylsilyloxy)aniline

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With methanol; 1,3-disulfonic acid imidazolium hydrogen sulfate at 20℃; for 0.0666667h; Green chemistry;	98%
With nano magnetic sulfated zirconia (Fe3O4 at ZrO2/SO42-) In neat (no solvent) at 20℃; for 0.25h; Green chemistry;	83%
With Kaolinitic clay; water for 0.0416667h; Irradiation; microwave;	63%

: 54840-15-2
4-N-tert-butoxycarbonylaminophenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With water at 100℃; for 2h; Inert atmosphere;	97%
With water at 150℃; for 2h; Subcritical conditions;	95%
HY-Zeolite In dichloromethane for 2h; Heating;	92%
With 3-butyl-l-methyl-1H-imidazol-3-iumtrifloroacetate In 1,4-dioxane; water at 70 - 72℃; for 2h;	82%
With H-β zeolite In dichloromethane for 10h; Heating;	71%

: 106-41-2
4-bromo-phenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With ammonium hydroxide at 20℃; for 10h; Catalytic behavior;	96%
With ammonia; triethylamine In water at 20℃; for 8h;	95%
With ammonium hydroxide at 20℃; for 12h; Catalytic behavior;	94%

: 2050-16-0
4,4'-dihydroxyazobenzene

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With zinc In methanol at 25℃; for 0.166667h; Inert atmosphere;	96%
With magnesium In methanol at 25℃; for 0.2h; Inert atmosphere;	95%
With sodium dithionite; water In dimethyl sulfoxide at 20℃; pH=7.4; Kinetics; phosphate buffer;
With hydrogenchloride; tin(ll) chloride
With sodium hydroxide; zinc

: 540-38-5
4-Iodophenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With ammonium hydroxide In water at 20℃; for 9h; Green chemistry;	95%
With copper(l) iodide; 2-carboxyquinoline N-oxide; potassium carbonate; ammonium hydroxide In dimethyl sulfoxide at 50℃; for 23h; Inert atmosphere;	90%
With copper(I) oxide; ammonium hydroxide; potassium carbonate at 140℃; for 13h; Inert atmosphere;	80%
With copper(l) iodide; ascorbic acid In ammonia at 25℃; for 18h; liquid NH3;	57%

: 89415-43-0
(4-aminophenyl)boronic acid

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With iron(III) oxide; oxygen In tetrahydrofuran Irradiation;	95%
With iron(III) oxide; oxygen In tetrahydrofuran at 20℃; Irradiation;	95%
With dihydrogen peroxide In water at 20℃; chemoselective reaction;	95%

: 84253-23-6
4-(2,4-Dimethyl-benzyloxy)-phenylamine

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In ethanol under 3040 Torr; for 15h;	94%

: 104-91-6
p-nitrosophenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With titanium(III) chloride In 1,4-dioxane at 20℃; for 4h; Product distribution; var. substituted nitrosobenzenes;	93%
With nickel; methyl cyclohexane at 100 - 125℃; under 73550.8 - 110326 Torr; Hydrogenation;
With hydrogenchloride; tin

: 117635-44-6
tert-butyldimethyl(4-nitrophenoxy)silane

A: 123-30-8
4-amino-phenol

B: 111359-74-1
4-[(tert-butyldimethylsilyl)oxy]aniline

Conditions

Conditions	Yield
With potassium fluoride; polymethylhydrosiloxane; palladium diacetate In tetrahydrofuran; water at 20℃; for 0.5h;	A 7% B 92%
With potassium fluoride; polymethylhydrosiloxane; palladium diacetate In tetrahydrofuran at 20℃; for 0.5h;	A 7% B 92%

: 13871-68-6
p-aminophenyl acetate

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With amberlyst-15 In methanol at 20℃; for 3h;	90%

: 103-14-0
4-(benzylamino)phenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With ammonium formate; zinc In ethylene glycol for 0.05h; microwave irradiation;	90%
With ammonium formate; magnesium In ethylene glycol for 0.05h; microwave irradiation;	90%

: 1016987-47-5
4-[[tris(propan-2-yl)silyl]oxy]aniline

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With potassium acetate In water; N,N-dimethyl-formamide at 70℃; for 22h;	90%

: 1145-76-2
benzyl 4-nitrophenyl ether

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With formic acid; potassium hydroxide In ethanol at 70℃; for 1h; Catalytic behavior; Reagent/catalyst;	89%
With Pd(0)EnCat; ammonium formate In N,N-dimethyl-formamide at 80℃; for 0.166667h; Irradiation; microwave;	20%

: 13795-24-9
benzyl 4-nitrophenyl carbonate

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With methanol; sodium tetrahydroborate; nickel(II) chloride hexahydrate at 20℃; for 0.25h; chemoselective reaction;	89%

: 1145-76-2
benzyl 4-nitrophenyl ether

A: 6373-46-2
p-benzyloxyaniline

B: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With hydrogen; platinum(IV) oxide In various solvent(s) at 25℃; for 10h;	A 88% B 7%

: 631-61-8
ammonium acetate

: 123-31-9
hydroquinone

A: 103-90-2
4-acetaminophenol

B: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With acetic acid at 160 - 230℃; for 15h; Temperature; Autoclave; Inert atmosphere;	A 88% B n/a

...Expand

: 7107-59-7
4-(N-Benzyloxycarbonylamino)phenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With methylmagnesium bromide; hydrogen; palladium diacetate; nickel diacetate In water at 45℃; for 19h;	88%
With methanol; sodium tetrahydroborate; nickel(II) chloride hexahydrate at 20℃; for 0.25h; chemoselective reaction;	86%

: 89415-43-0
(4-aminophenyl)boronic acid

: 80937-33-3
oxygen

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With triethanolamine In water at 20℃; for 18h; Sonication; Irradiation; Green chemistry;	88%

: 3-(4-nitro-phenoxymethyl)-benzoic acid ethyl ester

A: 120-33-2
ethyl 3-methylbenzoate

B: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With magnesium In methanol at 20℃; for 5h;	A n/a B 87%

: 111359-74-1
4-[(tert-butyldimethylsilyl)oxy]aniline

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With lithium acetate In water; N,N-dimethyl-formamide at 70℃; for 24h; Inert atmosphere;	87%
With sodium cyanide In ethanol; water at 80℃; for 38h; chemoselective reaction;	27.3%

: 100-02-7
4-nitro-phenol

: 108-24-7
acetic anhydride

A: 103-90-2
4-acetaminophenol

B: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With sodium tetrahydroborate; chloro-trimethyl-silane In methanol; water for 0.25h; Reagent/catalyst; Irradiation;	A 86% B 13%

...Expand

: 98-95-3
nitrobenzene

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With palladium diacetate; carbon monoxide; triphenylphosphine In sulfuric acid; butan-1-ol at 56℃; under 532 Torr; for 30h;	85%
With sulfuric acid; Pt/Al2O3; hydrogen; cetyltrimethylammonim bromide; zinc(II) sulfate In water at 120℃; under 7500.75 Torr; for 4h; Reagent/catalyst; Pressure;	83%
With formic acid; sulfate-doped zirconia; cetyltrimethylammonim bromide at 150℃; for 6h; Reagent/catalyst; Temperature; Inert atmosphere; Sealed tube;	51.3%

: 123-30-8
4-amino-phenol

: 104-88-1
4-chlorobenzaldehyde

: 1749-05-9
4-{[(4-chlorophenyl)methylidene]amino}phenol

Conditions

Conditions	Yield
for 24h; Ambient temperature;	100%
With piperidine In ethanol Condensation; Heating;	85%
With dodecatungstosilic acid; phosphorus pentoxide In neat (no solvent, solid phase) at 20℃;	82%

: 108-30-5
succinic acid anhydride

: 123-30-8
4-amino-phenol

: 62558-67-2
4-(4'-hydroxy-phenylamino)-4-oxo-butanoic acid

Conditions

Conditions	Yield
With sodium dodecyl-sulfate In methanol; water at 20℃; for 0.583333h;	100%
With sodium dodecyl-sulfate In water	87%
In water at 50℃;	86%

: 1118-02-1
trimethylsilyl isocyanate

: 123-30-8
4-amino-phenol

: 100238-66-2
(4-Trimethylsilanyloxy-phenyl)-urea

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 20 - 50℃; for 2h;	100%

: 24424-99-5
di-tert-butyl dicarbonate

: 123-30-8
4-amino-phenol

: 54840-15-2
4-N-tert-butoxycarbonylaminophenol

Conditions

Conditions	Yield
With triethylamine In methanol at 22℃; for 14h;	100%
With guanidine hydrochloride In ethanol at 35 - 40℃; for 0.0166667h;	100%
In tetrahydrofuran at 0℃; for 12h;	100%

: 71105-17-4
phenylene-1,2-diisothiocyanate

: 123-30-8
4-amino-phenol

: 75644-26-7
1-(4-hydroxyanilino-thiocarbonyl)-benzimidazolidine-2-thione

Conditions

Conditions	Yield
for 1h; Solid phase reaction; cyclization; addition;	100%
In acetonitrile for 0.5h; Ambient temperature;	81%

: 63673-58-5
2,6-dimethyl-4-oxo-5-phenyl-1,3-oxazinium perchlorate

: 123-30-8
4-amino-phenol

: 122664-34-0
perchlorate 2,6-dimethyl-5-phenyl-1-(4'-hydroxyphenyl)-4-oxopyrimidinium

Conditions

Conditions	Yield
In acetic acid for 48h; Ambient temperature;	100%
In acetic acid for 0.5h; Heating;	94%

: 13154-24-0
triisopropylsilyl chloride

: 123-30-8
4-amino-phenol

: 1016987-47-5
4-[[tris(propan-2-yl)silyl]oxy]aniline

Conditions

Conditions	Yield
With 1H-imidazole In dichloromethane at 20℃; for 26h; Inert atmosphere;	100%
With 1H-imidazole for 26h; Inert atmosphere;	85%
With 1H-imidazole In dichloromethane at 15℃; for 12h;	73.9%

: 123-30-8
4-amino-phenol

: 70237-44-4
4-amino(2H4)phenol

Conditions

Conditions	Yield
Stage #1: 4-amino-phenol With diclazuril; water-d2 at 175℃; for 0.333333h; microwave irradiation; Stage #2: With water	100%
With hydrogen chloride In water-d2 at 28 - 180℃; for 42h; Inert atmosphere; Sealed tube; Microwave irradiation;	50%
With hydrogenchloride; water-d2 In water-d2 at 180℃; for 7h; Microwave irradiation;

: 123-30-8
4-amino-phenol

: 4-hydroxybenzenediazonium tetrafluoroborate

Conditions

Conditions	Yield
With acetic acid; isopentyl nitrite In ethanol; water at -10℃; for 1.5h;	100%
With sodium tetrafluoroborate; perchloric acid; sodium nitrite In water at -10℃; for 24h;
With tetrafluoroboric acid; isopentyl nitrite In ethanol at 0℃; for 1h;

: 123-30-8
4-amino-phenol

: 350-46-9
4-Fluoronitrobenzene

: 6149-33-3
4-(4-nitrophenoxy)aniline

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 90℃;	100%
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 20℃; for 12h;	71%
With potassium carbonate In dimethyl sulfoxide at 70℃;	67%

: 123-30-8
4-amino-phenol

: 162364-72-9
7-benzyloxy-4-chloro-6-methoxyquinazoline

: 516526-37-7
4-((7-(benzyloxy )-6-methoxyquinazolin-4-yl)oxy)aniline

Conditions

Conditions	Yield
With sodium hydroxide; tetrabutyl-ammonium chloride In water; butanone for 2h; Heating / reflux;	100%
With sodium hydroxide; tetrabutyl-ammonium chloride In water; butanone for 2h; Heating / reflux;	100%
Stage #1: 4-amino-phenol With sodium hydride In dimethyl sulfoxide; mineral oil at 17 - 25℃; for 0.166667h; Inert atmosphere; Stage #2: 7-benzyloxy-4-chloro-6-methoxyquinazoline In dimethyl sulfoxide; mineral oil at 22 - 90℃; for 1h; Inert atmosphere;	91%

: 871024-38-3
4-chloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidine

: 123-30-8
4-amino-phenol

: 919278-08-3
4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]aniline

Conditions

Conditions	Yield
With caesium carbonate In 1-methyl-pyrrolidin-2-one at 120℃; for 16h; Product distribution / selectivity;	100%
With potassium carbonate In 1-methyl-pyrrolidin-2-one at 110℃; for 3h; Product distribution / selectivity;	60%
With potassium carbonate In 1-methyl-pyrrolidin-2-one at 110℃; for 2h;	60%

: 924909-13-7
1-benzyloxymethyl-4-chloro-1H-pyrazolo[3,4-b]pyridine

: 123-30-8
4-amino-phenol

: 924909-14-8
4-(1-benzyloxymethyl-1H-pyrazolo[3,4-b]pyridin-4-yloxy)aniline

Conditions

Conditions	Yield
Stage #1: 4-amino-phenol With potassium tert-butylate; potassium carbonate In 1-methyl-pyrrolidin-2-one at 20℃; for 1h; Stage #2: 1-benzyloxymethyl-4-chloro-1H-pyrazolo[3,4-b]pyridine In 1-methyl-pyrrolidin-2-one at 80℃; for 0.5h;	100%

: 123-30-8
4-amino-phenol

: 24801-88-5
3-(triethoxypropyl) isocyanate

: 1028843-30-2
1-(3-(triethoxysilyl)propyl)-3-(4-hydroxyphenyl)urea

Conditions

Conditions	Yield
In chloroform at 80℃; for 5h;	100%
In chloroform at 80℃; for 5h;	95%

: 128615-83-8
1-chloro-4-(4-methoxyphenyl)phthalazine

: 123-30-8
4-amino-phenol

: 1071584-40-1
4-(4-(4-methoxyphenyl)phthalazin-1-ylamino)phenol hydrochloride

Conditions

Conditions	Yield
In iso-butanol at 100℃;	100%
In iso-butanol at 100℃;

: 123-30-8
4-amino-phenol

: 95-01-2
2,4-Dihydroxybenzaldehyde

: 111279-02-8
4-((4-hydroxyphenylimino)methyl)benzene-1,3-diol

Conditions

Conditions	Yield
With acetic acid In ethanol for 2h; Reflux; Inert atmosphere;	100%

: 26153-38-8
3,5-dihydroxybenzaldehyde

: 123-30-8
4-amino-phenol

: (E)-5{(4-hydroxyphenylimino)methyl}benzene-1,3-diol

Conditions

Conditions	Yield
With magnesium sulfate In dichloromethane at 20℃; for 3h;	100%
In water at 25℃; for 2h;	92%
In water at 20℃; for 2h;

: 123-30-8
4-amino-phenol

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 2350-69-8
C9H13N2O(1+)*Cl(1-)

Conditions

Conditions	Yield
With trichlorophosphate at 20℃; Cooling with ice;	100%

: 26153-38-8
3,5-dihydroxybenzaldehyde

: 123-30-8
4-amino-phenol

: 1365617-17-9
5-[(4-hydroxy-phenylimino)-methyl]-benzene-1,3-diol

Conditions

Conditions	Yield
With sodium sulfate In dichloromethane at 20℃; for 1h;	100%
With sodium sulfate In dichloromethane at 20℃; for 3h; Solvent; Reagent/catalyst; Inert atmosphere;	93%

: 123-30-8
4-amino-phenol

: 127099-85-8, 780722-26-1
N-Cyanoguanidine

: 116604-04-7
1-carbamimidamido-N-(4-hydroxyphenyl)methanimidamide hydrochloride

Conditions

Conditions	Yield
In acetonitrile at 150℃; for 4.5h; Inert atmosphere;	100%

: 1118-02-1
trimethylsilyl isocyanate

: 123-30-8
4-amino-phenol

: 1566-41-2
1-(4-hydroxyphenyl)urea

Conditions

Conditions	Yield
In tetrahydrofuran at 65℃; for 6h;	100%

: 73583-41-2
bromo-4 chloro-3 pyridine

: 123-30-8
4-amino-phenol

: 4-((3-chloropyridin-4-yl)oxy)aniline

Conditions

Conditions	Yield
Stage #1: 4-amino-phenol With potassium tert-butylate In N,N-dimethyl acetamide at 20℃; for 0.5h; Stage #2: bromo-4 chloro-3 pyridine In N,N-dimethyl acetamide at 85℃; for 4h;	100%

: 2-((4-chlorobenzyl)oxy)-5-fluorobenzaldehyde

: 123-30-8
4-amino-phenol

: 4-((2-((4-chlorobenzyl)oxy)-5-fluorobenzyl)amino)phenol

Conditions

Conditions	Yield
Stage #1: 2-((4-chlorobenzyl)oxy)-5-fluorobenzaldehyde; 4-amino-phenol With acetic acid In methanol at 20℃; Inert atmosphere; Stage #2: With sodium cyanoborohydride In methanol Inert atmosphere;	99.8%

: 51779-32-9
iminodicarboxylic acid di-tert-butyl ester

: 123-30-8
4-amino-phenol

: 54840-15-2
4-N-tert-butoxycarbonylaminophenol

Conditions

Conditions	Yield
In tetrahydrofuran for 12h; Inert atmosphere;	99.46%

: 108-24-7
acetic anhydride

: 123-30-8
4-amino-phenol

: 103-90-2
4-acetaminophenol

Conditions

Conditions	Yield
With sodium dodecyl-sulfate In water	99%
With silica gel for 0.5h; Time; Milling;	99%
With sulfuric acid supported on poly(4-vinylpyridine) (P4VP) In dichloromethane at 20℃; for 1.25h;	98%

: 108-24-7
acetic anhydride

: 123-30-8
4-amino-phenol

: 2623-33-8
4-acetoxyacetanilide

Conditions

Conditions	Yield
With silver trifluoromethanesulfonate at 60℃; for 0.05h; neat (no solvent);	99%
With 2,3-dihydro-5,7-bismethyl-1,4-diazepine monohydroperchlorate In neat (no solvent) at 40℃; for 1h;	99%
With pyridine at 100℃;	90%

: 123-30-8
4-amino-phenol

: 532-55-8
Benzoyl isothiocyanate

: 5461-34-7
N1-Benzoyl-N2-<4-hydroxyphenyl>thiourea

Conditions

Conditions	Yield
In acetone for 0.5h; Heating;	99%
In acetone at 20℃; for 1h; Sonication;	91%
In acetone Ambient temperature;	71%

4-Aminophenol Consensus Reports

Related aminophenols 2-Aminophenol 3-Aminophenol
Related compounds Aniline Phenol

4-Aminophenol Specification

The 4-Aminophenol, with the CAS registry number 123-30-8, is also known as 4-Amino-1-hydroxybenzene; 4-Hydroxyaniline.It belongs to the product categories of Metabolites & Impurities;Building Blocks;C6 to C8;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Phenols. This chemical's molecular formula is C₆H₇NO and molecular weight is 109.13. Its EINECS number is 204-616-2. What's more,Its systematic name is 4-Aminophenol. 4-Aminophenol may discolor on exposure to air and light.. It is not compatible with strong oxidizing agents, acids, bases, acid chlorides, acid anhydrides, chloroformates, and you must not take it with incompatible materials, light, exposure to a. And also prevent it to broken down into hazardous decomposition products: Nitrogen oxides, carbon monoxide, carbon dioxide.

Physical properties about 4-Aminophenol are: (1)ACD/LogP: 0.013; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.20; (4)ACD/LogD (pH 7.4): 0.01; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 14.99; (8)ACD/KOC (pH 7.4): 23.99; (9)#H bond acceptors: 2; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.637; (13)Molar Refractivity: 32.371 cm3; (14)Molar Volume: 90.144 cm3; (15)Polarizability: 12.833 10-24cm3 ; (16)Surface Tension: 57.4010009765625 dyne/cm; (17)Density: 1.211 g/cm3; (18)Flash Point: 124.34 °C; (19)Enthalpy of Vaporization: 54.173 kJ/mol; (20)Boiling Point: 281.984 °C at 760 mmHg; (21)Vapour Pressure: 0.0020000000949949 mmHg at 25°C.

The 4-Aminophenol is Limited evidence of a carcinogenic effect ,harmful by inhalation and if swallowed and Possible risk of irreversible effects.When you use it,wear suitable protective clothing and gloves.After contact with skin, wash immediately with plenty of water (to be specified by the manufacturer) .The 4-Aminophenol is very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Avoid release to the environment. Refer to special instructions safety data sheet,And this material and/or its container must be disposed of as hazardous waste.

You can still convert the following datas into molecular structure:
(1)SMILES:c1cc(ccc1N)O;
(2)Std. InChI:InChI=1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2;
(3)Std. InChIKey:PLIKAWJENQZMHA-UHFFFAOYSA-N.

The toxicity data of 4-Aminophenol as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	56200ug/kg (56.2mg/kg)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
cat	LDLo	subcutaneous	37mg/kg (37mg/kg)		Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 72, Pg. 241, 1913.
cat	LDLo	subcutaneous	37mg/kg (37mg/kg)	BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 72, Pg. 241, 1913.
guinea pig	LDLo	subcutaneous	1500mg/kg (1500mg/kg)		Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 35, Pg. 401, 1895.
mammal (species unspecified)	LD50	oral	1530mg/kg (1530mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(10), Pg. 16, 1980.
mammal (species unspecified)	LD50	skin	6400mg/kg (6400mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(10), Pg. 16, 1980.
mammal (species unspecified)	LD50	unreported	563mg/kg (563mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(9), Pg. 19, 1983.
mouse	LD50	unreported	750mg/kg (750mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 50(3), Pg. 4, 1985.
mouse	LDLo	intraperitoneal	100mg/kg (100mg/kg)		Revue Belge de Pathologie et de Medecine Experimentale. Vol. 22, Pg. 1, 1952.
mouse	LDLo	subcutaneous	470mg/kg (470mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 188, Pg. 130, 1938.
rabbit	LD50	oral	10gm/kg (10000mg/kg)		Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 215, 1956.
rabbit	LD50	skin	> 10gm/kg (10000mg/kg)		BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat	LC50	inhalation	> 5mg/m3/1H (5mg/m3)		BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat	LD50	intraperitoneal	465mg/kg (465mg/kg)	BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN	Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 31, 1944.
rat	LD50	oral	375mg/kg (375mg/kg)		BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat	LD50	oral	375mg/kg (375mg/kg)	LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: MUSCLE WEAKNESS	BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat	LD50	unreported	675mg/kg (675mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 50(3), Pg. 4, 1985.

Product Name

4-Aminophenol

Synthetic route

4-Aminophenol Consensus Reports

4-Aminophenol Specification

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