4-Ethenylphenol acetate supplier

Name
4-Ethenylphenol acetate
EINECS 434-600-2
CAS No. 2628-16-2
Article Data46
CAS DataBase
Density 1.059 g/cm³
Solubility
Melting Point 7-8 °C(lit.)
Formula C₁₀H₁₀O₂
Boiling Point 260 °C at 760 mmHg
Molecular Weight 162.188
Flash Point 94 °C
Transport Information UN 2810
Appearance clear colorless liquid
Safety 36/37
Risk Codes 22-38-43
Molecular Structure
Hazard Symbols Xn
Synonyms Phenol,4-ethenyl-, acetate (9CI);Phenol, p-vinyl-, acetate (6CI,7CI,8CI);4-Acetoxystyrene;4-Vinylphenyl acetate;p-Acetoxystyrene;
PSA 26.30000
LogP 2.25490

Synthetic route

: 108-24-7
acetic anhydride

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Stage #1: p-Coumaric Acid With bis(1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl)sebacate; potassium acetate In DMF (N,N-dimethyl-formamide) at 150℃; for 2h; Stage #2: acetic anhydride In DMF (N,N-dimethyl-formamide) at 140℃; for 0.75h; Product distribution / selectivity;	97.5%
Stage #1: p-Coumaric Acid; potassium acetate In ISOPROPYLAMIDE at 135℃; for 3h; Stage #2: acetic anhydride In ISOPROPYLAMIDE at 20℃; for 0.633333h; Product distribution / selectivity;	71%

: 360068-17-3
4-(1,2-dibromoethyl)phenyl acetate

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With gallium; bis(cyclopentadienyl)titanium dichloride In tetrahydrofuran at 20℃; for 0.166667h; Inert atmosphere; Ultrasonic irradiation; chemoselective reaction;	96%
With bismuth(III) chloride; gallium In tetrahydrofuran at 20℃; for 0.5h;	96%
With bismuth(III) chloride; indium In methanol at 20℃; for 0.5h; Sonication; chemoselective reaction;	94%

: C10H10O2S

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With molybdenum hexacarbonyl In toluene for 2h; Reflux; chemoselective reaction;	92%

: 53744-50-6
4'-acetoxyphenylmethylcarbinol

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With 10H-phenothiazine; 1-ethyl-3-methylimidazolium hydrogensulfate at 150℃; for 6h; Temperature; Reagent/catalyst;	90%
With 4-tert-Butylcatechol; potassium hydroxide In N,N-dimethyl acetamide at 100 - 110℃; Reagent/catalyst; Temperature;	79.3%
With tert-butylcatechol In toluene at 90℃; for 0.5h; Reagent/catalyst; Temperature; Molecular sieve;	78%
With potassium hydrogensulfate at 175 - 200℃;
With acetic anhydride In N,N-dimethyl-formamide at 50℃;

: 2628-17-3
4-Vinylphenol

: 75-36-5
acetyl chloride

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With 10H-phenothiazine; triethylamine In tert-butyl methyl ether at -5 - 20℃; for 1h; Reagent/catalyst; Solvent; Green chemistry;	87.7%
With triethylamine In dichloromethane at 0℃; for 3h;	69%
With triethylamine In dichloromethane at 20℃;

: 108-24-7
acetic anhydride

: 2628-17-3
4-Vinylphenol

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
In N,N-dimethyl acetamide for 0.5h; Heating / reflux;	86%
With 10H-phenothiazine; triethylamine In tert-butyl methyl ether at -5 - 20℃; for 1h; Green chemistry;	58.6%
With dmap; triethylamine In dichloromethane at 23℃; for 0.5h; Inert atmosphere;	24%
With dmap; triethylamine In dichloromethane at 23℃; for 0.5h; Inert atmosphere;	24%
at 80℃; under 760.051 Torr; for 2h;	80.20 g

: 108-05-4
vinyl acetate

: 876-27-7
4-chlorophenyl acetate

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With manganese; trifluoroacetic acid; [2,2]bipyridinyl; cobalt(II) bromide In pyridine; DMF (N,N-dimethyl-formamide) at 50℃;	81%

: 7400-08-0
para-coumaric acid

: 108-24-7
acetic anhydride

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Stage #1: para-coumaric acid With 4-methoxy-phenol In water; N,N-dimethyl-formamide at 136℃; for 6h; Stage #2: acetic anhydride With pyridine In water; N,N-dimethyl-formamide at 30℃; for 0.5h;	75%

: 878-00-2
4-formylphenyl acetate

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With Methyltriphenylphosphonium bromide; potassium carbonate In tetrahydrofuran for 6h; Inert atmosphere; Reflux;	71%
Multi-step reaction with 2 steps 1: activated Zn powder / dimethylformamide / 50 °C 2: Ac2O / dimethylformamide / 50 °C View Scheme

: 878-00-2
4-formylphenyl acetate

: 1779-49-3
Methyltriphenylphosphonium bromide

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With potassium carbonate In tetrahydrofuran at 70℃; for 24h; Temperature; Wittig Olefination;	60.91%
With potassium carbonate In 1,4-dioxane for 16h; Reflux;
Stage #1: Methyltriphenylphosphonium bromide With n-butyllithium In tetrahydrofuran at 0℃; for 0.25h; Inert atmosphere; Stage #2: 4-formylphenyl acetate In tetrahydrofuran at 0 - 20℃; for 10h; Inert atmosphere;

: 878-00-2
4-formylphenyl acetate

: 2065-66-9
methyl-triphenylphosphonium iodide

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With potassium carbonate In tetrahydrofuran Inert atmosphere; Reflux;	44%
Stage #1: methyl-triphenylphosphonium iodide With potassium tert-butylate In diethyl ether at 0℃; for 4h; Stage #2: 4-formylphenyl acetate In diethyl ether at 20℃; for 10h;

: 878-00-2
4-formylphenyl acetate

: 2065-66-9
methyl-triphenylphosphonium iodide

A: 2628-16-2
p-acetoxystyrene

B: 791-28-6
Triphenylphosphine oxide

Conditions

Conditions	Yield
With Carbowax 6000 (liquid); potassium carbonate	A 10% B n/a

...Expand

: 68735-72-8
1-acetoxy-4-(1-acetoxy-ethyl)-benzene

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
at 480℃;
at 480℃;

: 27542-85-4
4-acetoxycinnamic acid

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With quinoline; copper

: 53744-50-6
4'-acetoxyphenylmethylcarbinol

: 108-24-7
acetic anhydride

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With aluminum oxide; acetic acid at 350℃; under 25 Torr;

: 1927-95-3
4-bromophenyl acetate

: 7486-35-3
tri-n-butyl(vinyl)tin

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With pyridine; tetrakis(triphenylphosphine) palladium(0); 2,6-di-tert-butyl-4-methyl-phenol; pyridine hydrogenfluoride 1.) toluene, reflux, 8 h, 2.) toluene, RT, 16 h; Yield given. Multistep reaction;

: 53744-50-6
4'-acetoxyphenylmethylcarbinol

KHSO4: KHSO4

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
at 175 - 200℃;

: 948888-24-2
3-bromo-2-(p-hydroxyphenyl) propionic acid

: 108-24-7
acetic anhydride

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Stage #1: 3-bromo-2-(p-hydroxyphenyl) propionic acid; 2-bromo-3-(p-hydroxyphenyl)propanoic acid With potassium carbonate In N,N-dimethyl-formamide at 65℃; for 1h; Heating / reflux; Stage #2: acetic anhydride In N,N-dimethyl-formamide at 65℃; for 0.25h; Heating / reflux;

: 123-07-9
4-Ethylphenol

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: sodium acetate 2: oxygen; chromium oxide-cobalt hydroxide(?)-calcium carbonate catalyst / 145 °C 3: copper oxide-chromium oxide / 130 °C / 102971 Torr / Hydrogenation 4: KHSO4 / 175 - 200 °C View Scheme

: 3245-23-6
p-ethylphenyl acetate

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: oxygen; chromium oxide-cobalt hydroxide(?)-calcium carbonate catalyst / 145 °C 2: copper oxide-chromium oxide / 130 °C / 102971 Torr / Hydrogenation 3: KHSO4 / 175 - 200 °C View Scheme

: 13031-43-1
4-acetyloxyacetophenone

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: palladium/charcoal; methanol / 30 °C / 5884.06 Torr / Hydrogenation 2: acetic acid; Al2O3 / 350 °C / 25 Torr View Scheme
Multi-step reaction with 2 steps 1: copper oxide-chromium oxide / 130 °C / 102971 Torr / Hydrogenation 2: KHSO4 / 175 - 200 °C View Scheme

: 93453-79-3
1-(4-hydroxyphenyl)ethanol

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: pyridine; diethyl ether 2: 480 °C View Scheme

: 99-93-4
4-Hydroxyacetophenone

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: aqueous NaOH 2: palladium/charcoal; methanol / 30 °C / 5884.06 Torr / Hydrogenation 3: acetic acid; Al2O3 / 350 °C / 25 Torr View Scheme
Multi-step reaction with 3 steps 1: methanol; Raney nickel / 70 - 80 °C / 102971 Torr / Hydrogenation 2: pyridine; diethyl ether 3: 480 °C View Scheme
Multi-step reaction with 3 steps 1: sodium carbonate / ethyl acetate / 8 h / 20 - 30 °C / Large scale 2: hydrogen; 5%-palladium/activated carbon / toluene / 15 - 20 °C / 6000.6 Torr / Large scale 3: potassium hydroxide; 4-tert-Butylcatechol / N,N-dimethyl acetamide / 100 - 110 °C View Scheme
Multi-step reaction with 3 steps 1: triethylamine / dichloromethane / 3 h / 0 - 30 °C 2: palladium on activated charcoal; hydrogen / methanol / 5 h / 30 °C / 15001.5 Torr 3: 10H-phenothiazine; 1-ethyl-3-methylimidazolium hydrogensulfate / 6 h / 150 °C View Scheme

: 108-95-2
phenol

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: BF3 2: aqueous NaOH 3: palladium/charcoal; methanol / 30 °C / 5884.06 Torr / Hydrogenation 4: acetic acid; Al2O3 / 350 °C / 25 Torr View Scheme

: 108-05-4
vinyl acetate

: 1927-95-3
4-bromophenyl acetate

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
With manganese; trifluoroacetic acid; [2,2]bipyridinyl; cobalt(II) bromide In pyridine; DMF (N,N-dimethyl-formamide) at 50℃; for 0.5h;

: 123-08-0
4-hydroxy-benzaldehyde

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere 2: potassium carbonate; Methyltriphenylphosphonium bromide / tetrahydrofuran / 6 h / Inert atmosphere; Reflux View Scheme
Multi-step reaction with 2 steps 1.1: sodium hydride / dimethyl sulfoxide / 0.25 h / Inert atmosphere; Cooling with ice 1.2: 5 h / 23 °C / Inert atmosphere 2.1: triethylamine; dmap / dichloromethane / 0.5 h / 23 °C / Inert atmosphere View Scheme
Multi-step reaction with 2 steps 1.1: sodium hydride / dimethyl sulfoxide / 0.25 h / Inert atmosphere 1.2: 5 h / 23 °C 2.1: triethylamine; dmap / dichloromethane / 0.5 h / 23 °C / Inert atmosphere View Scheme

: 7400-08-0
para-coumaric acid

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: pyridine; glycine / 8 h / 140 °C 2: 2 h / 80 °C / 760.05 Torr View Scheme

: 86952-89-8
4-(oxiran-2-yl)phenyl acetate

: 2628-16-2
p-acetoxystyrene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: potassium thioacyanate 2: molybdenum hexacarbonyl / toluene / 2 h / Reflux View Scheme

: 2628-16-2
p-acetoxystyrene

: 1675-54-3
diphenylolpropane diglycidyl ether

: C41H44O8

Conditions

Conditions	Yield
dmap at 85℃; for 60h;	100%

: 2628-16-2
p-acetoxystyrene

: 75-86-5
2-hydroxy-2-methylpropanenitrile

: 1132795-53-9
2-(4-acetoxyphenyl)propanenitrile

Conditions

Conditions	Yield
With 3-[bis-(4-methoxy-phenyl)-phosphanyl]-2H-isoquinolin-1-one; N-{6-[bis-(4-methoxy-phenyl)-phosphanyl]-pyridin-2-yl}-2,2-dimethyl-propionamide; bis(1,5-cyclooctadiene)nickel (0) In toluene at 35℃; for 40h; Inert atmosphere; regioselective reaction;	100%

: 2628-16-2
p-acetoxystyrene

: 383-73-3
bis(trifluoroacetyl)peroxide

: C13H10F6O4

Conditions

Conditions	Yield
In dichloromethane at 40℃; for 1h;	100%

: 336-64-1
bis(heptafluorobutyryl) peroxide

: 2628-16-2
p-acetoxystyrene

: C17H10F14O4

Conditions

Conditions	Yield
In dichloromethane at 40℃; for 1h;	100%

: 60556-87-8
2-carbonyl-3-butenenitrile

: 2628-16-2
p-acetoxystyrene

: 2-[(4-acetyloxy)phenyl]-3,4-dihydro-2H-pyran-6-carbonitrile

Conditions

Conditions	Yield
In acetonitrile at 81℃; for 24h; hetero-Diels-Alder cycloaddition;	99%

: 50-00-0
formaldehyd

: 2628-16-2
p-acetoxystyrene

: 4-(4-acetoxyphenyl)-1,3-dioxane

Conditions

Conditions	Yield
With 2,6-di-tert-butylphenoxy(difluoro)borane In 1,4-dioxane at 100℃; for 12h; Prins reaction;	99%
With bismuth(lll) trifluoromethanesulfonate In acetonitrile for 10h; Prins reaction; Heating;	77%

: 2628-16-2
p-acetoxystyrene

: 4-(1-fluoroethyl)phenyl acetate

Conditions

Conditions	Yield
With triethylsilane; tetrakis(triphenylphosphine) palladium(0); Selectfluor In acetonitrile at 0℃; for 2h; regioselective reaction;	99%

: 2628-16-2
p-acetoxystyrene

: 3245-23-6
p-ethylphenyl acetate

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen at 20℃; for 18h; Sealed tube;	99%
With 1% Pd on activated carbon; hydrogen In water at 20℃; under 760.051 Torr; for 2h; Reagent/catalyst; Green chemistry; chemoselective reaction;	99%
With hydrogen In toluene at 40℃; under 2250.23 Torr; Catalytic behavior; Reagent/catalyst; Schlenk technique; Glovebox;
With ammonia borane In water at 24.84℃; for 4h; Sonication; Green chemistry;

: 2628-16-2
p-acetoxystyrene

: 47241-75-8
(E)-4,4’-diacetoxystilbene

Conditions

Conditions	Yield
RuCl2(=CHPh)[1,3-ImH2]P(Cy)3 In dichloromethane at 40℃; for 2h;	98%
With Hoveyda-Grubbs catalyst second generation In dichloromethane at 40℃; for 15h;	93%
With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride In methanol; dichloromethane; water at 45℃; for 5h; Ionic liquid; Inert atmosphere; Catalyst solution in CH2Cl2/BMIM incapsulated within polydimethylsiloxane thimble;	80%
(1,3-dimesitylimidazolin-2-ylidene)(C2H4)RuCl2; (p-cymene)RuCl2 In toluene at 85℃; for 2h;	100 % Turnov.

: 2628-16-2
p-acetoxystyrene

: Umemoto's reagent

: 1417820-87-1
3,3,3-trifluoro-1-(4-acetoxyphenyl)-1-propanol

Conditions

Conditions	Yield
With tris[2-phenylpyridinato-C2,N]iridium(III); water In acetone at 20℃; for 3h; Schlenk technique; Inert atmosphere; Irradiation; regioselective reaction;	98%

: 2628-16-2
p-acetoxystyrene

: 149-30-4
2-Mercaptobenzothiazole

: 1446094-31-0
C17H15NO2S2

Conditions

Conditions	Yield
With trifluoroacetic acid In dichloromethane at 20℃; regioselective reaction;	98%

: 908133-83-5
ethyl 4-[7-bromo-1-(2-ethoxy-2-oxoethyl)-1H-indol-3-yl]butanoate

: 2628-16-2
p-acetoxystyrene

: C28H31NO6

Conditions

Conditions	Yield
With dicyclohexylmethylamine; triethylamine In 1,4-dioxane; hexane at 100℃; for 3h; Heck Reaction; Inert atmosphere;	98%

: 2628-16-2
p-acetoxystyrene

: 439584-65-3
4-(1,2-dihydroxyethyl)phenyl acetate

Conditions

Conditions	Yield
With osmium(VIII) oxide; 4-methylmorpholine N-oxide In water; acetone at 0 - 20℃; for 4h; Inert atmosphere;	97%
Stage #1: p-acetoxystyrene With sodium periodate; acetic acid; lithium bromide at 95℃; for 18h; Prevost-Woodward reaction; Stage #2: With potassium carbonate In methanol at 25℃; for 24h;
With Quinuclidine; osmium(VIII) oxide; tert-butyl alcohol In acetone at 25℃; for 12h;

aqueous DMF: aqueous DMF

: 4-bromocyclobutabenzene

: [(4-benzocyclobutenyl)vinyl] phenol

: [(4-benzocyclobutenyl)-vinyl] phenyl acetate

: 2628-16-2
p-acetoxystyrene

: 6163-58-2
tris-(o-tolyl)phosphine

: [(4-cyclobutenyl)vinyl] phenol

Conditions

Conditions	Yield
With potassium acetate; palladium diacetate In water; N,N-dimethyl-formamide	97%

...Expand

: 2628-16-2
p-acetoxystyrene

: 4-bromo-5, 5, 5-trifluoropentan-1-ol

: (E)-4-(6-hydroxy-3-(trifluoromethyl)hex-1-en-1-yl)phenyl acetate

Conditions

Conditions	Yield
With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene at 80℃; for 16h; Heck Reaction; Schlenk technique; Inert atmosphere;	97%

: 2628-16-2
p-acetoxystyrene

: 1129-37-9
4-nitrobenzaldehyde oxime

: C17H14N2O5

Conditions

Conditions	Yield
With sodium hypochlorite In dichloromethane; water	97%

: 2628-16-2
p-acetoxystyrene

: 2-bromo-1-(4-methylpent-3-en-1-yl)-1H-benzo[d]imidazole

: (E)-4-(3-(2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-3-yl)-3-methylbut-1-en-1-yl)phenyl acetate

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In 1,4-dioxane for 24h; Schlenk technique; Inert atmosphere; Irradiation; stereoselective reaction;	97%

: 2628-16-2
p-acetoxystyrene

: 2628-17-3
4-Vinylphenol

Conditions

Conditions	Yield
With ethanol; sodium hydroxide at 20℃; for 4h; Inert atmosphere;	96%
With sodium hydroxide In tetrahydrofuran; water at 20℃; for 4h; Cooling with ice; Inert atmosphere; Schlenk technique;	96%
With sodium hydroxide In ethanol at 20℃; for 4h; Inert atmosphere;	96%

: 2628-16-2
p-acetoxystyrene

: 86952-89-8
4-(oxiran-2-yl)phenyl acetate

Conditions

Conditions	Yield
Stage #1: p-acetoxystyrene With tris(μ-oxo)di[(1,4,7-trimethyl-1,4,7-triazanonane)manganese(IV)] hexafluorophosphate; scandium tris(trifluoromethanesulfonate) In acetonitrile at 20℃; for 0.166667h; Sealed tube; Stage #2: With dihydrogen peroxide In water; acetonitrile for 0.05h; Sealed tube;	96%
With oxone(R); PEG-supported α,α,α-trifluoroacetophenone; sodium hydrogencarbonate In 1,4-dioxane; water at 20℃; for 0.0833333h;	84%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 20℃; for 24h;	75%

: 2628-16-2
p-acetoxystyrene

: 74-88-4
methyl iodide

: 637-69-4
4-Methoxystyrene

Conditions

Conditions	Yield
With potassium hydroxide In water; acetone at 20℃; for 124h;	96%

: 2628-16-2
p-acetoxystyrene

: C11H9BrFNO4S2

: C21H17NO4S

Conditions

Conditions	Yield
With copper(l) iodide; bathophenanthroline; sodium carbonate In dichloromethane at 100℃; for 60h; Sealed tube; Inert atmosphere;	96%

: 2628-16-2
p-acetoxystyrene

: 13031-43-1
4-acetyloxyacetophenone

Conditions

Conditions	Yield
With perchloric acid; oxygen; palladium diacetate; p-benzoquinone; sodium nitrite In methanol; water at 20℃; for 5h; Wacker Oxidation; Schlenk technique; Sealed tube; Green chemistry;	95%
With iron(II) chloride In ethanol at 80℃; for 4h;	88%
With tert.-butylhydroperoxide; palladium(II) bis(diketonate) In benzene at 56℃;	84%

: 591-50-4
iodobenzene

: 2628-16-2
p-acetoxystyrene

: 93022-30-1, 13041-73-1
Trans-acetic acid 4-styrylphenyl ester

Conditions

Conditions	Yield
With triethylamine; poly{bis[(N-iPr-acrylamide)5-co-((4-vinylphenyl)PPh2)]PdCl2} In toluene at 100℃; for 20h; Heck reaction;	95%

: 2628-16-2
p-acetoxystyrene

: 3,4-dimethoxybenzenediazonium tetrafluoroborate

: 880354-47-2
(E)-1-(4'-acetoxyphenyl)-2-(3,4-dimethoxyphenyl)ethene

Conditions

Conditions	Yield
With palladium diacetate; sodium acetate In benzonitrile at 25℃; Heck arylation reaction;	95%

: 2628-16-2
p-acetoxystyrene

: 3,4,5-trimethoxybenzenediazonium tetrafluoroborate

: 134029-69-9
(E)-1-(4-acetoxyphenyl)-2-(2,3,4-trimethoxyphenyl)ethene

Conditions

Conditions	Yield
With Pd2(dba)4; sodium acetate In benzonitrile at 25℃; for 1h; Heck arylation reaction;	95%

: 2628-16-2
p-acetoxystyrene

: 72470-95-2
3,5-dimethoxybenzenediazonium tetrafluoroborate

: 18259-14-8, 63366-83-6
(E)-1-(4'-acetoxyphenyl)-2-(3,5-dimethoxyphenyl)ethene

Conditions

Conditions	Yield
With palladium diacetate; sodium acetate In benzonitrile at 25℃; for 3h; Heck arylation reaction;	95%

: 2628-16-2
p-acetoxystyrene

: 4-hydroxybenzenediazonium tetrafluoroborate

: (E)-1-acetyloxy-4-(4-hydroxystyryl)benzene

Conditions

Conditions	Yield
With sodium acetate; palladium diacetate In methanol at 20℃; for 12h; Heck Reaction; Inert atmosphere;	95%

: 2628-16-2
p-acetoxystyrene

: 1473394-59-0
4-ethoxy-4H-1,4-benzoxaphosphorin-4-oxide

: 1473394-82-9
(E)-3-[2-(4-acetoxyphenyl)ethenyl]-4-ethoxy-4H-1,4-benzoxaphosphorin-4-oxide

Conditions

Conditions	Yield
With copper diacetate; palladium diacetate; trimethylpyruvic acid; silver carbonate at 80℃; for 6h;	95%

4-Ethenylphenol acetate Specification

The CAS registry number of 4-Ethenylphenol acetate is 2628-16-2. In addition, the molecular formula is C₁₀H₁₀O₂ and the molecular weight is 162.19. It is also called phenol, 4-ethenyl-,1-acetate. What's more, it is a kind of clear colorless liquid and should be stored in a cool and dry place.

Physical properties about this chemical are: (1)ACD/LogP: 2.14; (2)ACD/LogD (pH 5.5): 2.14; (3)ACD/LogD (pH 7.4): 2.14; (4)ACD/BCF (pH 5.5): 24.77; (5)ACD/BCF (pH 7.4): 24.77; (6)ACD/KOC (pH 5.5): 346.22; (7)ACD/KOC (pH 7.4): 346.22; (8)#H bond acceptors: 2; (9)#Freely Rotating Bonds: 3; (10)Polar Surface Area: 26.3 Å²; (11)Index of Refraction: 1.546; (12)Molar Refractivity: 48.51 cm³; (13)Molar Volume: 153 cm³; (14)Polarizability: 19.23 ×10^-24cm³; (15)Surface Tension: 35.6 dyne/cm; (16)Density: 1.059 g/cm³; (17)Flash Point: 94 °C; (18)Enthalpy of Vaporization: 49.77 kJ/mol; (19)Boiling Point: 260 °C at 760 mmHg; (20)Vapour Pressure: 0.0125 mmHg at 25°C.

Uses of 4-Ethenylphenol acetate: it can react with thiocyanic acid; ammonium salt to get acetic acid 4-thiocyanatoacetyl-phenyl ester. This reaction will need reagents CAN and O₂ and solvent methanol. The reaction time is 30 minutes at reaction temperature of 0 °C. The yield is about 68%.

4-Acetoxystyrene can react with thiocyanic acid; ammonium salt to get acetic acid 4-thiocyanatoacetyl-phenyl ester

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to the skin and may cause sensitization by skin contact. And it is harmful if swallowed. When you are using it, wear suitable protective clothing and gloves.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(Oc1ccc(cc1)\C=C)C
(2)InChI: InChI=1/C10H10O2/c1-3-9-4-6-10(7-5-9)12-8(2)11/h3-7H,1H2,2H3
(3)InChIKey: JAMNSIXSLVPNLC-UHFFFAOYAV

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
rabbit	LDLo	skin	200mg/kg (200mg/kg)	United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-1190-1082,
rat	LD50	oral	1503mg/kg (1503mg/kg)	United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-1190-1082,
rat	LD50	skin	> 2gm/kg (2000mg/kg)	United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-1190-1082,

Product Name

4-Ethenylphenol acetate

Synthetic route

4-Ethenylphenol acetate Specification

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