Product Name

  • Name

    4-Hydroxybenzhydrazide

  • EINECS 226-326-5
  • CAS No. 5351-23-5
  • Article Data126
  • CAS DataBase
  • Density 1.318 g/cm3
  • Solubility
  • Melting Point 264-266 °C (dec.)(lit.)
  • Formula C7H8N2O2
  • Boiling Point 274.61°C (rough estimate)
  • Molecular Weight 152.153
  • Flash Point
  • Transport Information
  • Appearance White solid.
  • Safety 26-37/39
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 5351-23-5 (4-Hydroxybenzhydrazide)
  • Hazard Symbols IrritantXi; CorrosiveC
  • Synonyms Benzoicacid, p-hydroxy-, hydrazide (6CI,7CI,8CI);(4-Hydroxybenzoyl)hydrazine;(p-Hydroxybenzoyl)hydrazine;4-Hydroxybenzhydrazide;4-Hydroxybenzohydrazide;4-Hydroxybenzoic acid hydrazide;4-Hydroxybenzoyl hydrazide;INHd 25;NSC 647;p-Hydroxybenzhydrazide;p-Hydroxybenzohydrazide;p-Hydroxybenzoic acidhydrazide;p-Hydroxybenzoic hydrazide;p-Hydroxybenzoyl hydrazide;4-hydroxybenzohydrazide;Benzoic acid, 4-hydroxy-, hydrazide;
  • PSA 75.35000
  • LogP 1.08690

Synthetic route

methyl 4-hydroxylbenzoate
99-76-3

methyl 4-hydroxylbenzoate

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
With hydrazine hydrate for 18h; Reflux;99%
With hydrazine hydrate In methanol for 0.05h; Microwave irradiation;94.6%
With hydrazine hydrate In ethanol for 0.2h; Reflux; Microwave irradiation;93%
C21H18Cl2N4O4
62500-75-8

C21H18Cl2N4O4

A

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

B

2-Dimethylamino-4,6-dihydrazino-sym-triazine
6476-81-9

2-Dimethylamino-4,6-dihydrazino-sym-triazine

Conditions
ConditionsYield
With hydrazine hydrate In 1,4-dioxane for 2h; Heating;A 98%
B 55%
Ethyl 4-hydroxybenzoate
120-47-8

Ethyl 4-hydroxybenzoate

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
With hydrazine hydrate In ethanol; water Inert atmosphere; Reflux;96%
With hydrazine hydrate In ethanol Inert atmosphere; Reflux;96%
With hydrazine hydrate In ethanol Inert atmosphere; Reflux;96%
4-hydroxy-benzoic acid
99-96-7

4-hydroxy-benzoic acid

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
Stage #1: 4-hydroxy-benzoic acid With sulfuric acid In ethanol for 6h; Reflux;
Stage #2: With hydrazine hydrate; sodium hydrogencarbonate; acetic acid Reflux;		89%
With hydrazine at 250℃; Microwave irradiation;83%
With hydrazine hydrochloride
2,4-bis(4-chlorocarbonylphenoxy)-6-methoxy-s-triazine
61370-95-4

2,4-bis(4-chlorocarbonylphenoxy)-6-methoxy-s-triazine

A

2,4‐dihydrazinyl‐6‐methoxy‐1,3,5‐triazine
19992-28-0

2,4‐dihydrazinyl‐6‐methoxy‐1,3,5‐triazine

B

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
With hydrazine hydrate In 1,4-dioxane for 2h; Heating;
C29H18Cl2N4O4
62500-77-0

C29H18Cl2N4O4

A

2-Diphenylamino-4,6-dihydrazino-sym-triazine
35968-21-9

2-Diphenylamino-4,6-dihydrazino-sym-triazine

B

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
With hydrazine hydrate In 1,4-dioxane for 2h; Heating;
4-Hydroxy-benzoic acid [1-[(2S,4S)-4-((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-2-yl]-eth-(E)-ylidene]-hydrazide; hydrochloride
66996-57-4

4-Hydroxy-benzoic acid [1-[(2S,4S)-4-((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-2-yl]-eth-(E)-ylidene]-hydrazide; hydrochloride

A

daunomycin hydrochloride
23541-50-6

daunomycin hydrochloride

B

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
With water at 37℃; Rate constant; also half-conversion period, pH 5.58, 0.01 M phosphate buffer;
4-hydroxy-benzoic acid
99-96-7

4-hydroxy-benzoic acid

acid

acid

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2SO4 / Heating
2: hydrazine / H2O / Heating
View Scheme
4-hydroxy-benzoic acid
99-96-7

4-hydroxy-benzoic acid

CS2

CS2

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 80 percent / H2SO4
2: 70 percent / 35percent aq. hydrazine / Ambient temperature
View Scheme
tert-butyl 2-(4-hydroxybenzoyl)hydrazinecarboxylate
521290-74-4

tert-butyl 2-(4-hydroxybenzoyl)hydrazinecarboxylate

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
deprotection;
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: manganese(IV) oxide; sodium cyanide / 24 h / 20 °C
2: hydrazine hydrate / ethanol / 3 h / 70 °C
View Scheme
Multi-step reaction with 2 steps
1: iodine; potassium hydroxide / 2 h / 0 °C
2: hydrazine hydrate / ethanol / 70 °C
View Scheme
N-(4-hydroxybenzoyl)imidazole

N-(4-hydroxybenzoyl)imidazole

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
With hydrazine hydrate for 0.0166667h; Sonication;
4-hydroxybenzoyl chloride
28141-24-4

4-hydroxybenzoyl chloride

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
With hydrazine hydrate for 0.5h; Reflux;
With dmap; triethylamine; hydrazine In dichloromethane at 20℃; for 0.5h;
ethanol
64-17-5

ethanol

4-hydroxy-benzoic acid
99-96-7

4-hydroxy-benzoic acid

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

Conditions
ConditionsYield
Stage #1: ethanol; 4-hydroxy-benzoic acid
Stage #2: With hydrazine hydrate for 5.25h; Reflux;
1-(2-methoxy-6-pentadecylbenzyl)-1H-1,2,3-triazole-4-carbaldehyde

1-(2-methoxy-6-pentadecylbenzyl)-1H-1,2,3-triazole-4-carbaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

(E)-N'-[{1-(2-methoxy-6-pentadecylbenzyl)-1H-1,2,3-triazol-4-yl}methylene]-4-hydroxybenzohydrazide

(E)-N'-[{1-(2-methoxy-6-pentadecylbenzyl)-1H-1,2,3-triazol-4-yl}methylene]-4-hydroxybenzohydrazide

Conditions
ConditionsYield
In ethanol for 0.5h; Reflux;100%
vanillin
121-33-5

vanillin

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

4-hydroxy-N’-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]benzohydrazide

4-hydroxy-N’-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]benzohydrazide

Conditions
ConditionsYield
With acetic acid In methanol for 3h; Reflux;100%
5-nitrofurane-2-carboxaldehyde
698-63-5

5-nitrofurane-2-carboxaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

4-hydroxy-N’-((5-nitrofuran-2-yl)methylene)benzohydrazide
965-52-6

4-hydroxy-N’-((5-nitrofuran-2-yl)methylene)benzohydrazide

Conditions
ConditionsYield
In water Acidic conditions; Reflux;99.8%
In ethanol for 2h; Reflux;91.4%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

4-hydroxy-N’-[(E)-(4-hydroxyphenyl)methylidene]benzohydrazide
100872-56-8

4-hydroxy-N’-[(E)-(4-hydroxyphenyl)methylidene]benzohydrazide

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water at 20℃; for 24h;99%
With acetic acid In methanol for 2h; Reflux;96%
With acetic acid In ethanol for 3h; Reflux;90%
With acetic acid In isopropyl alcohol at 20℃; for 24h;82%
3,5-dihydroxybenzaldehyde
26153-38-8

3,5-dihydroxybenzaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

(E)-N'-(3,5-dihydroxybenzylidene)-4-hydroxybenzohydrazide
1607472-21-8

(E)-N'-(3,5-dihydroxybenzylidene)-4-hydroxybenzohydrazide

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water at 20℃; for 24h;99%
1-Phenylethanol
98-85-1, 13323-81-4

1-Phenylethanol

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

4-hydroxy-N'-(1-phenylethyl)benzohydrazide

4-hydroxy-N'-(1-phenylethyl)benzohydrazide

Conditions
ConditionsYield
With nickel(II) triflate; 1,3-bis(dicyclohexylphosphine)propane In tert-Amyl alcohol at 120℃; for 48h; Inert atmosphere; Glovebox; Schlenk technique; Molecular sieve;99%
4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

hexakis(4-formylphenoxy)cyclotriphosphazene
77958-57-7

hexakis(4-formylphenoxy)cyclotriphosphazene

C84H66N15O18P3

C84H66N15O18P3

Conditions
ConditionsYield
In tetrahydrofuran for 18h; Reflux;98.6%
4,4′,4″‑[(1,3,5‑triazine‑2,4,6‑triyl)tris(oxy)]tribenzaldehyde
3140-75-8

4,4′,4″‑[(1,3,5‑triazine‑2,4,6‑triyl)tris(oxy)]tribenzaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

2,4,6-tris[4-{(E)-[2'-(4-hydroxyphenylcarbonyl)hydrazinylidene]methyl}phenoxy]-1,3,5-triazine
1363379-35-4

2,4,6-tris[4-{(E)-[2'-(4-hydroxyphenylcarbonyl)hydrazinylidene]methyl}phenoxy]-1,3,5-triazine

Conditions
ConditionsYield
In tetrahydrofuran Reflux;98.6%
4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

salicylic acid pentafluorophenyl ester
187806-42-4

salicylic acid pentafluorophenyl ester

N-(4-hydroxybenzoyl)-N'-salicylhydrazine
41697-26-1

N-(4-hydroxybenzoyl)-N'-salicylhydrazine

Conditions
ConditionsYield
In N,N-dimethyl-formamide Ambient temperature;98%
Diphenylacetaldehyde
947-91-1

Diphenylacetaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

diphenylacetaldehyde p-hydroxybenzoylhydrazone
386283-90-5

diphenylacetaldehyde p-hydroxybenzoylhydrazone

Conditions
ConditionsYield
With acetic acid In ethanol for 4h; Reflux;98%
3-acetyl-4-hydroxychromen-2-one
2555-37-5

3-acetyl-4-hydroxychromen-2-one

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

3-{N-[(4'-hydroxybenzoyl)hydrazono]ethyl}-4-hydroxycoumarin

3-{N-[(4'-hydroxybenzoyl)hydrazono]ethyl}-4-hydroxycoumarin

Conditions
ConditionsYield
In propan-1-ol for 24h; Reflux;98%
4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carboxylic acid

1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carboxylic acid

N'-(4-hydroxybenzoyl)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbohydrazide

N'-(4-hydroxybenzoyl)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbohydrazide

Conditions
ConditionsYield
Stage #1: 4-hydroxybenzoic acid hydrazide; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carboxylic acid With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate In N,N-dimethyl-formamide for 0.333333h;
Stage #2: With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 1h;		98%
3,5-diodosalicylaldehyde
2631-77-8

3,5-diodosalicylaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

4-hydroxy-N'-(3,5-diiodo-2-hydroxybenzylidene)benzohydrazide

4-hydroxy-N'-(3,5-diiodo-2-hydroxybenzylidene)benzohydrazide

Conditions
ConditionsYield
In methanol for 0.5h;97%
3-acetyl-7-hydroxy-chromen-2-one
10441-27-7

3-acetyl-7-hydroxy-chromen-2-one

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

(E)-4-hydroxy-N'-(1-(7-hydroxy-2-oxo-2H-chromen-3-yl)ethylidene)benzohydrazide

(E)-4-hydroxy-N'-(1-(7-hydroxy-2-oxo-2H-chromen-3-yl)ethylidene)benzohydrazide

Conditions
ConditionsYield
With acetic acid In ethanol at 80℃; for 1h; Microwave irradiation;97%
benzo[b]thiophene-3-carboxylic acid
5381-25-9

benzo[b]thiophene-3-carboxylic acid

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

N'3-(4-hydroxybenzoyl)benzo[b]thiophene-3-carbohydrazide

N'3-(4-hydroxybenzoyl)benzo[b]thiophene-3-carbohydrazide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 6h;97%
sodium 2-formylbenzenesulfonate
1008-72-6

sodium 2-formylbenzenesulfonate

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

sodium 2-{(E)-[2-(4-hydroxybenzoyl)hydrazinylidene]methyl}benzenesulfonate

sodium 2-{(E)-[2-(4-hydroxybenzoyl)hydrazinylidene]methyl}benzenesulfonate

Conditions
ConditionsYield
In methanol for 2h; Reflux;97%
5-Methylfurfural
620-02-0

5-Methylfurfural

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

4-hydroxy-N′-((5-methylfuran-2-yl)methylene)benzohydrazide

4-hydroxy-N′-((5-methylfuran-2-yl)methylene)benzohydrazide

Conditions
ConditionsYield
Stage #1: 4-hydroxybenzoic acid hydrazide With acetic acid In water for 0.0833333h; Sonication;
Stage #2: 5-Methylfurfural In dimethyl sulfoxide at 20℃; for 0.5h; Sonication;		97%
8-acetyl-7-hydroxycoumarin
6748-68-1

8-acetyl-7-hydroxycoumarin

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

OHC6H4C12H9O4N2

OHC6H4C12H9O4N2

Conditions
ConditionsYield
In propan-1-ol for 24h; Heating;96%
4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

4-hydroxy-N’-[(E)-(4-methylphenyl)methylidene]benzohydrazide monomethanolate

4-hydroxy-N’-[(E)-(4-methylphenyl)methylidene]benzohydrazide monomethanolate

Conditions
ConditionsYield
acetic acid In ethanol for 4h; Heating / reflux;96%
With acetic acid In methanol for 2h; Reflux;80%
benzaldehyde
100-52-7

benzaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

4-hydroxy-N’-[(E)-benzylidene]benzohydrazide

4-hydroxy-N’-[(E)-benzylidene]benzohydrazide

Conditions
ConditionsYield
With acetic acid In methanol for 2h; Reflux;96%
acetic acid In ethanol for 4h; Heating / reflux;86%
With acetic acid In isopropyl alcohol at 20℃; for 24h;62%
5-ethyl-thiophene-2-carbaldehyde
36880-33-8

5-ethyl-thiophene-2-carbaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

4-hydroxybenzoic acid (5-ethylthiophen-2-ylmethylene)hydrazide

4-hydroxybenzoic acid (5-ethylthiophen-2-ylmethylene)hydrazide

Conditions
ConditionsYield
acetic acid In ethanol for 4h; Heating / reflux;96%
3-bromo-5H-pyrido[3,2-b]pyrrolizin-5-one

3-bromo-5H-pyrido[3,2-b]pyrrolizin-5-one

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

N'-[3-bromo-5H-pyrido[3,2-b]pyrrolizin-5-ylidene]-4-hydroxybenzohydrazide

N'-[3-bromo-5H-pyrido[3,2-b]pyrrolizin-5-ylidene]-4-hydroxybenzohydrazide

Conditions
ConditionsYield
In ethanol for 24h; Reflux;96%
5-nitrothiophene-2-carboxaldehyde diacetate
14289-24-8

5-nitrothiophene-2-carboxaldehyde diacetate

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

4-hydroxy-benzoic acid [(5-nitro-thiophen-2-yl)methylene]hydrazide

4-hydroxy-benzoic acid [(5-nitro-thiophen-2-yl)methylene]hydrazide

Conditions
ConditionsYield
With sulfuric acid In ethanol; water; acetic acid95.09%
benzaldehyde
100-52-7

benzaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

DY162
51771-18-7

DY162

Conditions
ConditionsYield
In ethanol for 6h; Heating;95%
In ethanol for 4h; Reflux;76%
With sulfuric acid; acetic acid In ethanol; water Reflux;72%
With potassium hydroxide In methanol at 80℃; for 2h;
5-nitro-2-thiophenecarboxaldehyde
4521-33-9

5-nitro-2-thiophenecarboxaldehyde

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

4-hydroxybenzoic acid (5-nitrothiophen-2-ylmethylene)hydrazide

4-hydroxybenzoic acid (5-nitrothiophen-2-ylmethylene)hydrazide

Conditions
ConditionsYield
acetic acid In ethanol for 4h; Heating / reflux;95%
In ethanol; water Heating;86%
4-(4-octoxyphenyl)benzoyl chloride
62918-50-7

4-(4-octoxyphenyl)benzoyl chloride

4-hydroxybenzoic acid hydrazide
5351-23-5

4-hydroxybenzoic acid hydrazide

C28H32N2O4
1193305-26-8

C28H32N2O4

Conditions
ConditionsYield
With sodium carbonate In tetrahydrofuran; water at 20℃;95%

4-Hydroxybenzhydrazide Specification

The Benzoic acid,4-hydroxy-, hydrazide, with the CAS registry number 5351-23-5 and EINECS registry number 226-326-5, has the systematic name and IUPAC name of 4-hydroxybenzohydrazide. It is a kind of white to slightly beige fine crystalline powder, and belongs to the following product categories: Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes; Benzoic acid; Phenols. And the molecular formula of the chemical is C7H8N2O2.

The characteristics of Benzoic acid,4-hydroxy-, hydrazide are as followings: (1)ACD/LogP: -0.33; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.33; (4)ACD/LogD (pH 7.4): -0.39; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 15.65; (8)ACD/KOC (pH 7.4): 13.65; (9)#H bond acceptors: 4; (10)#H bond donors: 4; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 32.78 Å2; (13)Index of Refraction: 1.622; (14)Molar Refractivity: 40.65 cm3; (15)Molar Volume: 115.3 cm3; (16)Polarizability: 16.11×10-24cm3; (17)Surface Tension: 62.7 dyne/cm; (18)Density: 1.318 g/cm3.

Uses of Benzoic acid,4-hydroxy-, hydrazide: It can react with 2-amino-pyridine-3-carbaldehyde to produce 4-hydroxy-benzoic acid (2-amino-pyridin-3-ylmethylene)-hydrazide. This reaction will need reagent glacial acetic acid, and the menstruum ethanol. The reaction time is 3 hours with heating, and the yield is about 67%.

You should be cautious while dealing with this chemical. It irritates to eyes, respiratory system and skin. Therefore, you had better take the following instructions: Wear suitable gloves and eye/face protection, and if in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: O=C(c1ccc(O)cc1)NN
(2)InChI: InChI=1/C7H8N2O2/c8-9-7(11)5-1-3-6(10)4-2-5/h1-4,10H,8H2,(H,9,11)
(3)InChIKey: ZMZGIVVRBMFZSG-UHFFFAOYAN

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