Product Name

  • Name

    4-Hydroxystyrene

  • EINECS 220-103-6
  • CAS No. 2628-17-3
  • Article Data155
  • CAS DataBase
  • Density 1.055 g/cm3
  • Solubility Slightly miscible with water.
  • Melting Point 73 °C
  • Formula C8H8O
  • Boiling Point 206.2 °C at 760 mmHg
  • Molecular Weight 120.151
  • Flash Point 92.3 °C
  • Transport Information
  • Appearance
  • Safety 26-39
  • Risk Codes 22-41
  • Molecular Structure Molecular Structure of 2628-17-3 (4-Hydroxystyrene)
  • Hazard Symbols HarmfulXn
  • Synonyms Phenol,p-vinyl- (6CI,7CI,8CI);4-Ethenylphenol;4-Hydroxystyrene;4-Vinylphenol;p-Hydroxystyrene;p-Vinylphenol;
  • PSA 20.23000
  • LogP 2.03520

Synthetic route

para-coumaric acid
7400-08-0

para-coumaric acid

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With sodium hydroxide at 160℃; for 5h;99.3%
With cucumber juice at 30 - 35℃; for 24h; Inert atmosphere; Green chemistry;94%
With aluminum oxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; hydroquinone In methanol for 0.333333h; microwave irradiation;85%
Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
Stage #1: Methyltriphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: 4-hydroxy-benzaldehyde In tetrahydrofuran at 20℃; for 1h; Wittig Olefination;
98%
Stage #1: Methyltriphenylphosphonium bromide With potassium tert-butylate; sodium hydride In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: 4-hydroxy-benzaldehyde In tetrahydrofuran at 20℃; for 19h;
95%
Stage #1: Methyltriphenylphosphonium bromide With n-butyllithium In tetrahydrofuran; hexane at 0℃; for 2h; Schlenk technique;
Stage #2: 4-hydroxy-benzaldehyde In tetrahydrofuran at 0 - 20℃;
89%
malonic acid
141-82-2

malonic acid

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With ethylenediamine In N,N-dimethyl-formamide at 150℃; for 6h; Reagent/catalyst; Solvent; Large scale;98%
With piperidine; 4-methoxy-phenol In hexane; 2-methoxy-ethanol at 65℃; for 24h; Reagent/catalyst; Temperature; Solvent;87.4%
With piperidine In pyridine at 115℃; for 4h; Knoevenagel condensation reaction;86%
p-Coumaric Acid
7400-08-0

p-Coumaric Acid

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With 4-methoxy-phenol In water; N,N-dimethyl-formamide at 150℃; for 4h; Solvent;97%
With 1-methyl-1H-imidazole; sodium hydrogencarbonate for 0.333333h; Heating; microwave irradiation;94%
With bis(1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl)sebacate; potassium acetate In DMF (N,N-dimethyl-formamide) at 150℃; for 1.5h; Product distribution / selectivity;94%
N,N-dimethyl-L-tyrosine N-oxide
19704-86-0

N,N-dimethyl-L-tyrosine N-oxide

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
potassium acetate In N,N-dimethyl acetamide at 123℃; for 2.4h; Product distribution / selectivity;97%
p-acetoxystyrene
2628-16-2

p-acetoxystyrene

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With ethanol; sodium hydroxide at 20℃; for 4h; Inert atmosphere;96%
With sodium hydroxide In tetrahydrofuran; water at 20℃; for 4h; Cooling with ice; Inert atmosphere; Schlenk technique;96%
With ethanol; sodium hydroxide at 20℃; for 4h; Inert atmosphere;96%
N,N-dimethyl-L-tyrosine N-oxide
19704-86-0

N,N-dimethyl-L-tyrosine N-oxide

A

p-Coumaric Acid
7400-08-0

p-Coumaric Acid

B

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
potassium acetate In N,N-dimethyl acetamide at 123℃; for 2.5h; Product distribution / selectivity;A 4%
B 96%
4-Vinylphenylboronic acid
2156-04-9

4-Vinylphenylboronic acid

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With N,N-dimethyl-p-toluidine N-oxide In dichloromethane at 20℃; for 0.0166667h;95%
With urea hydrogen peroxide adduct In acetonitrile at 27 - 29℃; for 0.75h; Temperature; Solvent; Green chemistry; chemoselective reaction;95%
With copper(II) sulfate hydrate; potassium hydroxide In water at 20℃; for 24h;91%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With potassium tert-butylate; Methyltriphenylphosphonium bromide In tetrahydrofuran at 0 - 20℃; for 16h;95%
Multi-step reaction with 2 steps
1: pyridine; glycine / 3 h / 80 °C / Sealed tube
2: pyridine; glycine / 8 h / 140 °C
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / dichloromethane / 2 h / 20 °C
2: potassium carbonate / tetrahydrofuran / 24 h / 70 °C
3: sodium hydroxide; methanol / 0.5 h / 20 °C
View Scheme
4-bromo-phenol
106-41-2

4-bromo-phenol

vinyl magnesium bromide
1826-67-1

vinyl magnesium bromide

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In tetrahydrofuran -78 deg C, 10 min, reflux, 0.5 h;91%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

diethyl malonate
105-53-3

diethyl malonate

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With morpholine; 4-methoxy-phenol In N,N-dimethyl-formamide at 70℃; for 12h;89.4%
1-bromo-4-ethenyl-benzene
2039-82-9

1-bromo-4-ethenyl-benzene

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; boric acid; palladium diacetate; caesium carbonate In 1-methyl-pyrrolidin-2-one at 80℃; for 24h; Schlenk technique; Inert atmosphere;89%
4-bromo-phenol
106-41-2

4-bromo-phenol

tri-n-butyl(vinyl)tin
7486-35-3

tri-n-butyl(vinyl)tin

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium (0); tri-tert-butyl phosphine In diethyl ether at 20℃; for 48h; Stille cross-coupling;84%
p-acetoxystyrene
2628-16-2

p-acetoxystyrene

A

(R)-(+)-4-hydroxyphenyloxirane
1176829-46-1

(R)-(+)-4-hydroxyphenyloxirane

B

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With dikegulac; water; urea hydrogen peroxide adduct In dichloromethane at 20℃; for 10h; Enzymatic reaction;A 5%
B 78%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With tris(triphenylphosphine)rhodium(l) chloride; triphenylphosphine; isopropyl alcohol In tetrahydrofuran at 25℃; for 8h; Reagent/catalyst; chemoselective reaction;78%
Cl-Mo(O)=CH2
84809-63-2

Cl-Mo(O)=CH2

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

A

4-Vinylphenol
2628-17-3

4-Vinylphenol

B

2-allylphenol
695-84-1

2-allylphenol

Conditions
ConditionsYield
With salicylaldehyde In tetrahydrofuranA 21%
B 77%
Cl-Mo(O)=CH2
84809-63-2

Cl-Mo(O)=CH2

salicylaldehyde
90-02-8

salicylaldehyde

A

4-Vinylphenol
2628-17-3

4-Vinylphenol

B

2-allylphenol
695-84-1

2-allylphenol

Conditions
ConditionsYield
With 4-hydroxy-benzaldehyde In tetrahydrofuranA 21%
B 77%
4-Hydroxyacetophenone
99-93-4

4-Hydroxyacetophenone

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With potassium hydroxide In isopropyl alcohol at 200℃; for 1.33333h; Reagent/catalyst; Time;76%
Multi-step reaction with 3 steps
1: 100 percent / N,N-diisopropylethylamine / CH2Cl2 / 4 h
2: 97 percent / NaBH4 / aq. ethanol
3: 59 percent / 2-bromo-1,3,2-benzodioxaborole, N,N-diisopropylethylamine / CH2Cl2 / 3 h
View Scheme
Multi-step reaction with 4 steps
1: aqueous NaOH
2: palladium/charcoal; methanol / 30 °C / 5884.06 Torr / Hydrogenation
3: acetic acid; Al2O3 / 350 °C / 25 Torr
4: aqueous KOH
View Scheme
4-Iodophenol
540-38-5

4-Iodophenol

vinyl magnesium bromide
1826-67-1

vinyl magnesium bromide

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In tetrahydrofuran for 1.16667h;75%
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In tetrahydrofuran for 0.166667h; further catalyst; Yield given;
N,N-dimethyl-L-tyrosine N-oxide
19704-86-0

N,N-dimethyl-L-tyrosine N-oxide

A

N,N-dimethylhydroxylamine
5725-96-2

N,N-dimethylhydroxylamine

B

p-Coumaric Acid
7400-08-0

p-Coumaric Acid

C

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
In N,N-dimethyl acetamide at 130℃; Product distribution / selectivity; Cope Elimination;A n/a
B 75%
C 3.3%
4-Methoxystyrene
637-69-4

4-Methoxystyrene

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With sodium thioethylate In N,N-dimethyl-formamide for 0.5h; Heating;70%
4-vinylbenzyl chloride
1073-67-2

4-vinylbenzyl chloride

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; boric acid; palladium diacetate; caesium carbonate In 1-methyl-pyrrolidin-2-one at 100℃; for 14h; Schlenk technique; Inert atmosphere;67%
1-(4-iodophenyl)ethanol
68120-56-9, 104013-25-4, 53207-29-7

1-(4-iodophenyl)ethanol

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With copper(l) iodide; 8-quinolinol; potassium hydroxide In water; dimethyl sulfoxide; tert-butyl alcohol at 100℃; for 48h; Inert atmosphere;60%
(RS)-1-<4-(2-methoxyethoxy)methoxyphenyl>ethanol
135921-81-2

(RS)-1-<4-(2-methoxyethoxy)methoxyphenyl>ethanol

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With bromocatecholborane; N-ethyl-N,N-diisopropylamine In dichloromethane for 3h;59%
With bromocatecholborane; N-ethyl-N,N-diisopropylamine In dichloromethane for 3h; Mechanism;59%
methyl-triphenylphosphonium iodide
2065-66-9

methyl-triphenylphosphonium iodide

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
Stage #1: methyl-triphenylphosphonium iodide With potassium tert-butylate In tetrahydrofuran for 1h; Inert atmosphere;
Stage #2: 4-hydroxy-benzaldehyde In tetrahydrofuran at 25℃; for 24h; Wittig reaction; Inert atmosphere;
58%
With potassium tert-butylate In tetrahydrofuran Wittig Olefination;
4-((3H-diazirin-3-yl)methyl)phenol

4-((3H-diazirin-3-yl)methyl)phenol

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
In dichloromethane at 20℃; for 2h; UV-irradiation;52%
3-(4-acetoxyphenyl)acrylic acid
27542-85-4, 50363-92-3, 15486-19-8

3-(4-acetoxyphenyl)acrylic acid

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With aluminum oxide; potassium hydroxide; ammonium acetate In water for 0.166667h; microwave irradiation;49%
methyl phenylphosphonium bromide

methyl phenylphosphonium bromide

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane at 0 - 20℃; for 12h; Inert atmosphere;47%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

Methylenetriphenylphosphorane
19493-09-5

Methylenetriphenylphosphorane

4-Vinylphenol
2628-17-3

4-Vinylphenol

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at 20℃; for 24h; Wittig Olefination; Green chemistry;47%
4-Vinylphenol
2628-17-3

4-Vinylphenol

H,ethyl (1-(N-tert-butoxycarbonylamino)-2-phenyl)ethylphosphonate
289506-29-2

H,ethyl (1-(N-tert-butoxycarbonylamino)-2-phenyl)ethylphosphonate

ethyl,4-ethenylphenyl (1-(N-tert-butoxycarbonylamino)-2-phenyl)ethylphosphonate
289506-30-5

ethyl,4-ethenylphenyl (1-(N-tert-butoxycarbonylamino)-2-phenyl)ethylphosphonate

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In dichloromethane Condensation;100%
perfluoro(2-propoxypropionyl) fluoride
2062-98-8, 125037-08-3

perfluoro(2-propoxypropionyl) fluoride

4-Vinylphenol
2628-17-3

4-Vinylphenol

C14H7F11O3

C14H7F11O3

Conditions
ConditionsYield
With triethylamine In dichloromethane; N,N-dimethyl-formamide at 40℃; for 4h; Inert atmosphere;99.5%
4-Vinylphenol
2628-17-3

4-Vinylphenol

4-ethylcyclohexanol
4534-74-1

4-ethylcyclohexanol

Conditions
ConditionsYield
With hydrogen In water at 70℃; under 7500.75 Torr; for 8h; Autoclave;99.2%
4-Vinylphenol
2628-17-3

4-Vinylphenol

4-Ethylphenol
123-07-9

4-Ethylphenol

Conditions
ConditionsYield
With hydrazine hydrate In acetonitrile at 30℃; for 24h;99%
With hydrogen In methanol at 20℃; for 24h; chemoselective reaction;93%
Multi-step reaction with 2 steps
1: 1 percent / Nocardia resting cells / aq. phosphate buffer / 48 h / 28 °C / pH 7.0 / Enzymatic reaction
2: Nocardia resting cells / aq. phosphate buffer / 24 h / 28 °C / pH 7.0 / Enzymatic reaction
View Scheme
tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

4-Vinylphenol
2628-17-3

4-Vinylphenol

1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-ethenyl benzene
84494-81-5

1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-ethenyl benzene

Conditions
ConditionsYield
With triethylamine In dichloromethane; N,N-dimethyl-formamide at 20℃; for 3h;99%
In N,N-dimethyl-formamide at 0 - 20℃; for 24h;34 g
1-bromo-2-(2-methoxyethoxy)ethane
54149-17-6

1-bromo-2-(2-methoxyethoxy)ethane

4-Vinylphenol
2628-17-3

4-Vinylphenol

1-(2-(2-methoxyethoxy)ethoxy)-4-vinylbenzene

1-(2-(2-methoxyethoxy)ethoxy)-4-vinylbenzene

Conditions
ConditionsYield
Stage #1: 4-Vinylphenol With potassium tert-butylate In acetonitrile for 1h; Reflux;
Stage #2: 2-bromoethyl 2-methoxyethyl ether In acetonitrile for 6h; Reflux; Inert atmosphere;
96%
Stage #1: 4-Vinylphenol With potassium tert-butylate In acetonitrile for 1h; Reflux;
Stage #2: 2-bromoethyl 2-methoxyethyl ether In acetonitrile for 6h; Inert atmosphere; Reflux;
96%
1-bromo dodecane
112-29-8

1-bromo dodecane

4-Vinylphenol
2628-17-3

4-Vinylphenol

1-(decyloxy)-4-vinylbenzene
134322-24-0

1-(decyloxy)-4-vinylbenzene

Conditions
ConditionsYield
With potassium carbonate In acetone at 60℃; for 12h; Inert atmosphere; Schlenk technique;96%
2-chloroethyl methyl ether
627-42-9

2-chloroethyl methyl ether

4-Vinylphenol
2628-17-3

4-Vinylphenol

1-(2-methoxyethoxy)-4-vinylbenzene

1-(2-methoxyethoxy)-4-vinylbenzene

Conditions
ConditionsYield
Stage #1: 4-Vinylphenol With potassium tert-butylate In acetonitrile for 1h; Reflux;
Stage #2: 2-chloroethyl methyl ether In acetonitrile for 6h; Reflux; Inert atmosphere;
95%
Stage #1: 4-Vinylphenol With potassium tert-butylate In acetonitrile for 1h;
Stage #2: 2-chloroethyl methyl ether In acetonitrile for 6h; Inert atmosphere;
95%
(trifluoromethyl)trimethylsilane
81290-20-2

(trifluoromethyl)trimethylsilane

4-Vinylphenol
2628-17-3

4-Vinylphenol

(4-(2,2-difluorocyclopropyl)phenoxy)trimethylsilane

(4-(2,2-difluorocyclopropyl)phenoxy)trimethylsilane

Conditions
ConditionsYield
With sodium iodide In tetrahydrofuran at 65℃; Inert atmosphere;95%
5-bromoresorcinol
106120-04-1

5-bromoresorcinol

4-Vinylphenol
2628-17-3

4-Vinylphenol

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With {1,3-bis[2,6-bis(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}dichloro(pyridine)palladium; caesium carbonate In neat (no solvent) at 100℃; for 12h; Heck Reaction;93%
methyl(phenyl)(divinyl)silane
17983-32-3

methyl(phenyl)(divinyl)silane

4-Vinylphenol
2628-17-3

4-Vinylphenol

methylphenyl-bis(4-hydroxystyryl)silane

methylphenyl-bis(4-hydroxystyryl)silane

Conditions
ConditionsYield
Stage #1: methyl(phenyl)(divinyl)silane; 4-Vinylphenol In dichloromethane at 40℃; for 0.25h; Inert atmosphere; Green chemistry;
Stage #2: With Grubbs catalyst first generation In dichloromethane for 8h; Inert atmosphere; Green chemistry;
92.5%
4-Vinylphenol
2628-17-3

4-Vinylphenol

chloroacetyl chloride
79-04-9

chloroacetyl chloride

4-chloroacetoxystyrene
861446-20-0

4-chloroacetoxystyrene

Conditions
ConditionsYield
With triethylamine In diethyl ether for 2h;92%
With triethylamine In diethyl ether for 2h;92%
tert-butyl (4,4-dimethoxycyclohexa-2,5-dien-1-ylidene)carbamate
106501-78-4

tert-butyl (4,4-dimethoxycyclohexa-2,5-dien-1-ylidene)carbamate

4-Vinylphenol
2628-17-3

4-Vinylphenol

tert-butyl {3-[2-(4-hydroxyphenyl)-2-methoxyethyl]-4-methoxyphenyl}carbamate

tert-butyl {3-[2-(4-hydroxyphenyl)-2-methoxyethyl]-4-methoxyphenyl}carbamate

Conditions
ConditionsYield
With 1,1'-binaphthyl-2,2'-diyl hydrogenphosphate In toluene at 30℃; for 12h; regioselective reaction;92%
chloroform
67-66-3

chloroform

4-Vinylphenol
2628-17-3

4-Vinylphenol

acetone
67-64-1

acetone

2-methyl-2-(4-vinylphenoxy)propionic acid

2-methyl-2-(4-vinylphenoxy)propionic acid

Conditions
ConditionsYield
With tetrabutylammomium bromide; sodium hydroxide at 40℃; Temperature; Reagent/catalyst; Green chemistry;91.6%
1,2,3-trimethoxybenzene
621-23-8

1,2,3-trimethoxybenzene

4-Vinylphenol
2628-17-3

4-Vinylphenol

4-(1-(2,4,6-trimethoxyphenyl)ethyl)phenol

4-(1-(2,4,6-trimethoxyphenyl)ethyl)phenol

Conditions
ConditionsYield
With diphenyl hydrogen phosphate In 1,2-dichloro-ethane at 100℃; for 16h; regiospecific reaction;91%
With diphenyl hydrogen phosphate In dichloromethane at 100℃; for 22h;1.22 g
2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine
940-71-6

2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine

4-Vinylphenol
2628-17-3

4-Vinylphenol

2,2,4,4,6,6-hexakis-(4-vinyl-phenoxy)-2λ5,4λ5,6λ5-[1,3,5,2,4,6]triazatriphosphinine

2,2,4,4,6,6-hexakis-(4-vinyl-phenoxy)-2λ5,4λ5,6λ5-[1,3,5,2,4,6]triazatriphosphinine

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 20 - 60℃; for 23h;91%

4-Hydroxystyrene Chemical Properties

Molecular Formula: C8H8O
Molar mass: 120.15 g/mol
EINECS: 220-103-6
Density: 1.055 g/cm3
Flash Point: 92.3 °C
Index of Refraction: 1.602
Boiling Point: 206.2 °C at 760 mmHg
Vapour Pressure: 0.168 mmHg at 25°C
Melting point: 73 ºC
Sensitive: Hygroscopic
Product categories of 4-Vinylphenol (2628-17-3): Aromatic Phenols
Structure of 4-Vinylphenol (2628-17-3):
           
XLogP3-AA: 2.4
H-Bond Donor: 1
H-Bond Acceptor: 1
Systematic Name: 4-Vinylphenol 
SMILES: Oc1ccc(\C=C)cc1 
InChI: InChI=1/C8H8O/c1-2-7-3-5-8(9)6-4-7/h2-6,9H,1H2 
InChIKey: FUGYGGDSWSUORM-UHFFFAOYAQ 
Std. InChI: InChI=1S/C8H8O/c1-2-7-3-5-8(9)6-4-7/h2-6,9H,1H2 
Std. InChIKey: FUGYGGDSWSUORM-UHFFFAOYSA-N

4-Hydroxystyrene Toxicity Data With Reference

1.    

eye-rbt 100 mg SEV

    EPASR*    United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401M St., S.W., Washington, DC 20460) History Unknown 8EHQ-1285-0579S .
2.    

skn-rbt LDLo:200 mg/kg

    EPASR*    United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401M St., S.W., Washington, DC 20460) History Unknown 8EHQ-1285-0579S .
3.    

ocu-rbt LDLo:50 mg/kg

    EPASR*    United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401M St., S.W., Washington, DC 20460) History Unknown 8EHQ-1285-0579S .

4-Hydroxystyrene Safety Profile

Poison by skin and eye contact. Severe eye irritant. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes: Xn
Risk Statements:
22:  Harmful if swallowed 
41:  Risk of serious damage to eyes
Safety Statements:
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
39:  Wear eye/face protection

4-Hydroxystyrene Specification

 4-Vinylphenol (2628-17-3) also can be called Poly(4-vinylphenol) ; 4-Hydroxystyrene ; 4-Ethenylphenol ; Poly(p-vinylphenol) and phenol, 4-ethenyl- .

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