4-methoxybenzamide supplier

Name
4-Methoxybenzamide
EINECS 222-319-6
CAS No. 3424-93-9
Article Data403
CAS DataBase
Density 1.144 g/cm³
Solubility
Melting Point 164-167 °C(lit.)
Formula C₈H₉NO₂
Boiling Point 295.803 °C at 760 mmHg
Molecular Weight 151.165
Flash Point 161.563 °C
Transport Information
Appearance White crystalline powder
Safety 22-24/25
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xn
Synonyms p-Anisamide(6CI,7CI,8CI);Anisamide;NSC 11139;p-Methoxybenzamide;
PSA 52.32000
LogP 1.49440

Synthetic route

: 874-90-8
4-methoxybenzonitrile

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With C18H57O3P6Ru2(1+)C6H5O(1-)C6H6O; water In 1,4-dioxane for 6h; Time; Sealed tube; Inert atmosphere; Schlenk technique;	100%
With [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II); water; 2-(diphenylphosphino)-N,N-dimethylpyridine-4-amine In 1,2-dimethoxyethane at 80℃; for 5h;	99%
With C12H24O16Ru3*2H2O In water at 110℃; for 13h; Catalytic behavior; Schlenk technique; Inert atmosphere;	99%

: 123-11-5
4-methoxy-benzaldehyde

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With hydroxylamine; C33H28F3N5O3Ru(1+)*Cl(1-) In water at 60℃; for 0.5h; Catalytic behavior; Sonication;	99%
Stage #1: 4-methoxy-benzaldehyde With hydroxylamine hydrochloride; caesium carbonate In water; dimethyl sulfoxide at 100℃; Stage #2: With palladium diacetate In water; dimethyl sulfoxide at 125℃; chemoselective reaction;	97%
With copper(ll) sulfate pentahydrate; hydroxylamine hydrochloride; sodium acetate at 110℃; for 2h; Neat (no solvent);	97%

: 100-09-4
4-methoxybenzoic acid

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
Stage #1: 4-methoxybenzoic acid With 1,3,5-trichloro-2,4,6-triazine; potassium carbonate In tetrahydrofuran for 0.0166667h; Milling; Stage #2: With ammonium thiocyanate In tetrahydrofuran for 0.0833333h; Milling;	99%
With pyridine; urea for 0.00833333h; microwave irradiation;	90%
Stage #1: 4-methoxybenzoic acid With thionyl chloride In tetrahydrofuran at 50℃; for 1h; Stage #2: With ammonium hydroxide In tetrahydrofuran at 0℃; for 0.0833333h;	84%

: 19486-73-8
N-tert-butyl-4-methoxybenzamide

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
scandium tris(trifluoromethanesulfonate) In nitromethane at 170℃; for 1h; Irradiation;	99%
With t-butyldimethylsiyl triflate In toluene at 100℃; for 8h;	74%

: 619-57-8
p-hydroxybenzamide

: 616-38-6
carbonic acid dimethyl ester

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With dmap at 135℃; under 3000.3 Torr; for 7h; Pressure; Temperature; Reagent/catalyst;	99%

: 100-07-2
4-methoxy-benzoyl chloride

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With ammonia Inert atmosphere;	98%
With ammonia at -10 - 20℃; for 1h; Temperature;	96.3%
With ammonia In water at 20℃; for 1h;	79%

: 105-13-5
4-Methoxybenzyl alcohol

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; ammonia; oxygen In water; N,N-dimethyl-formamide at 80℃; under 1520.1 Torr; for 5h; Green chemistry;	98%
Stage #1: 4-Methoxybenzyl alcohol With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; ammonia; oxygen; copper(II) nitrate In water; dimethyl sulfoxide at 80℃; under 760.051 Torr; for 5h; Stage #2: With Acetaldehyde oxime In water; dimethyl sulfoxide at 110℃; for 24h; Inert atmosphere;	97%
With ammonia; oxygen In water at 150℃; under 22502.3 Torr; for 3h;	96.5%

: 2393-23-9
4-methoxy-benzylamine

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With manganese(IV) oxide at 130℃; under 4560.31 Torr; for 3h;	98%
With dihydrogen peroxide at 80℃; for 10h; Inert atmosphere;	96%
With (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); potassium tert-butylate In tert-butyl alcohol at 70℃; for 12h;	95%

: 3532-17-0
4-methoxybenzoyl azide

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With (1,4-diazabicyclo{2.2.2}-octane)zinc(II) tetrahydoborate In tetrahydrofuran for 48h; Ambient temperature;	97%
With 1,3-diadamantane-4,5-dihydroimidazole chloride; potassium tert-butylate; bis(pinacol)diborane; copper(l) chloride In toluene at 25℃; for 4h; Schlenk technique; Inert atmosphere;	94%
With sodium tetrahydroborate; copper(II) sulfate In methanol at 0 - 5℃; for 1h;	92%

: 874-90-8
4-methoxybenzonitrile

A: 3424-93-9
4-methoxyphenylacetamide

B: 5373-87-5
4-methoxybenzamidoxime

Conditions

Conditions	Yield
With hydroxylamine In ethanol for 3h; Reagent/catalyst; Reflux;	A 97% B n/a
With hydroxylamine hydrochloride; sodium hydroxide In ethanol; water Reflux;

: 104-92-7
1-bromo-4-methoxy-benzene

: 201230-82-2
carbon monoxide

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With 2-(2'-pyridyl)(di(1-adamantyl)phosphino)benzene; ammonia; palladium diacetate In 1,4-dioxane at 120℃; under 1500.15 Torr; for 16h; Autoclave;	96%
With tris-(dibenzylideneacetone)dipalladium(0); (2R)-1-[(1R)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene; ammonium carbamate; sodium hydrogencarbonate In 1,4-dioxane at 100℃; for 20h; Inert atmosphere;	93%
With dmap; bis-triphenylphosphine-palladium(II) chloride; formamide In 1,4-dioxane at 120℃; under 3750.38 Torr; for 18h;	69%

: 1-(4-methoxybenzoyl)piperidine-2,6-dione

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With lithium hydroxide monohydrate In water at 20℃; for 2h;	96%

: 120158-06-7
tert-butyl (4-methoxybenzoyl)carbamate

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With trifluoroacetic acid In dichloromethane for 1h; Ambient temperature;	95%
With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Reagent/catalyst;

: 201230-82-2
carbon monoxide

: 696-62-8
para-iodoanisole

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With ammonium hydroxide; 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane; palladium diacetate In toluene at 130℃; under 5171.62 Torr; Temperature; Autoclave;	95%
With 1,4-diaza-bicyclo[2.2.2]octane; N-methoxylamine hydrochloride; sodium iodide; palladium dichloride In acetonitrile at 90℃; under 3800.26 Torr; for 8h; Autoclave; Inert atmosphere;	93%
With 1,4-diaza-bicyclo[2.2.2]octane; palladium 10% on activated carbon; ammonium carbamate; potassium iodide In acetonitrile at 90℃; for 8h; Autoclave; Green chemistry;	90%

: 3717-21-3, 3717-22-4, 140461-28-5, 140461-29-6, 3235-04-9
p-methoxyl benzaldoxime

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With silver tetrafluoroborate; chloro(1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene)gold(I) at 100℃; for 20h; Beckmann rearrangement; Sealed tube; Neat (no solvent);	95%
With C55H45ClN5P2Ru(1+)*Cl(1-) In water at 110℃; for 12h; Sealed tube;	94%
With C82H80N4O6; mercury dichloride In tetrahydrofuran; water; toluene at 20℃; for 5h; Beckmann Rearrangement;	93%

: 3717-22-4
(Z)-para-methoxybenzaldehyde oxime

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With toluene-4-sulfonic acid; 1,2-bis-(diphenylphosphino)ethane; carbonyl(dihydro)tris(triphenylphosphine)ruthenium(II) In toluene Heating;	93%
With cerium(III) chloride; silica gel; sodium iodide for 0.0666667h; Beckmann rearrangement; microwave irradiation;	80%

: 104-92-7
1-bromo-4-methoxy-benzene

: 15226-74-1, 61091-28-9, 61117-58-6
dicobalt octacarbonyl

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With 1H-imidazole; 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; ammonium chloride; N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 90℃; for 3h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Sealed tube;	93%

: 38388-44-2
2-(4-methoxybenzoylamino)-2-methylpropionic acid

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With copper dichloride In dimethyl sulfoxide at 120℃; for 11h;	93%
With copper dichloride In dimethyl sulfoxide at 120℃; for 11h;	93%

: 3717-21-3, 3717-22-4, 3235-04-9, 140461-28-5, 140461-29-6
(E)-4-methoxybenzaldoxime

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
bis[dichloro(pentamethylcyclopentadienyl)iridium(III)] In toluene at 111℃; for 6h;	92%
With indium(III) chloride; 4-methoxybenzonitrile In toluene for 18h; Reflux;	91%
In ethanol for 20h; Quantum yield; Irradiation;

: 2746-25-0
p-Methoxybenzyl bromide

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
Stage #1: p-Methoxybenzyl bromide With ammonia; iodine In water at 60℃; for 4h; Stage #2: With ammonia; dihydrogen peroxide In water at 0 - 20℃;	92%

: 104-93-8
4-Methylanisole

: 100-46-9
benzylamine

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
Stage #1: benzylamine With N-chloro-succinimide In acetonitrile at 20℃; for 3h; Green chemistry; Stage #2: p-methylanizole With tert.-butylhydroperoxide; iron(II) acetate In decane; acetonitrile at 82℃; for 22h; Green chemistry; Stage #3: With palladium 10% on activated carbon; hydrogen In methanol at 20℃; for 12h; Green chemistry;	92%

: 104-93-8
4-Methylanisole

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; iron(III) chloride hexahydrate; tetrabutylammonium iodide; ammonium hydroxide In water at 80℃; for 18h; Sealed tube;	91%
With tert.-butylhydroperoxide; ammonium chloride; calcium carbonate In dihydrogen peroxide; acetonitrile at 80℃; for 10h; Catalytic behavior; Inert atmosphere;	60%

: 3717-22-4
(Z)-para-methoxybenzaldehyde oxime

2: 2

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
bis[dichloro(pentamethylcyclopentadienyl)iridium(III)] In toluene at 111℃; for 6h;	90%

: 123-11-5
4-methoxy-benzaldehyde

A: 3424-93-9
4-methoxyphenylacetamide

B: 874-90-8
4-methoxybenzonitrile

C: 100-09-4
4-methoxybenzoic acid

Conditions

Conditions	Yield
With H2SO4*2NH2OH; Rh(OH)x/Al2O3 In water for 7h; Heating;	A 90% B 5 % Chromat. C 9 % Chromat.
Stage #1: 4-methoxy-benzaldehyde With pyridine; sodium persulfate; tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy; 1,1,1,3,3,3-hexamethyl-disilazane In acetonitrile at 0.2℃; for 24h; Molecular sieve; Sealed tube; Irradiation; Stage #2: With tetrabutyl ammonium fluoride In tetrahydrofuran; acetonitrile for 1h; Molecular sieve;

...Expand

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With sodium azide; iodine; sodium hydrogencarbonate In water at 100℃; for 2h; Reagent/catalyst; Temperature; Solvent;	90%
With ammonia; iodine In water at 60℃; for 1h; Lieben-Haller-Bauer reaction;	83%
With ammonia; water; iodine In tetrahydrofuran at 20℃; for 24h; Haller-Bauer reaction;	83%
With sodium azide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen; copper dichloride In water; N,N-dimethyl-formamide at 120℃; under 760.051 Torr; for 15h; Schlenk technique; chemoselective reaction;	67%
With tert.-butylhydroperoxide; ammonia; tetra-(n-butyl)ammonium iodide In water at 100℃; for 16h; Green chemistry;	53%

: 7732-18-5
water

: 874-90-8
4-methoxybenzonitrile

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With [{Au(SIPr)}2(μ-OH)][BF4] In tetrahydrofuran at 140℃; for 2h; Reagent/catalyst; Concentration; Microwave irradiation;	90%

: 696-62-8
para-iodoanisole

: potassium ferrocyanide

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With water; potassium carbonate In dimethyl sulfoxide at 110℃; for 12h;	90%

: 768-60-5
4-methoxyphenylacetylen

: 3424-93-9
4-methoxyphenylacetamide

Conditions

Conditions	Yield
With ammonia; dihydrogen peroxide; iodine In water; dimethyl sulfoxide at 20℃; for 3h; Irradiation;	90%

: 2393-23-9
4-methoxy-benzylamine

A: 3424-93-9
4-methoxyphenylacetamide

B: 874-90-8
4-methoxybenzonitrile

Conditions

Conditions	Yield
With water; oxygen at 140℃; under 3800.26 Torr; for 10h;	A 89% B n/a
With ammonium hydroxide; oxygen In tert-Amyl alcohol at 110℃; under 1500.15 Torr; for 16h;	A 13.6% B 79.3%

: 3424-93-9
4-methoxyphenylacetamide

: 2362-64-3
p-methoxythiobenzamide

Conditions

Conditions	Yield
With tetraphosphorus decasulfide In 1,4-dioxane at 50 - 68℃; for 3h; Temperature;	100%
With pyridin-1-ium-1-yl[pyridin-1-ium-1-yl(sulfido)phosphinothioyl]sulfanyl-sulfido-thioxo-phosphane In acetonitrile for 0.5h; Reflux;	88%
With Lawessons reagent In tetrahydrofuran at 20℃; Reflux;	80%

: 3424-93-9
4-methoxyphenylacetamide

: 100-51-6
benzyl alcohol

: 7465-87-4
N-benzyl-4-methoxybenzamide

Conditions

Conditions	Yield
With barium trifluoromethanesulfonate In toluene for 18h; Reflux; Inert atmosphere;	100%
With C23H24ClIrN3OS(1+)*F6P(1-); caesium carbonate In toluene at 120℃;	96%
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; caesium carbonate In toluene at 140℃; for 12h;	84%

: 3424-93-9
4-methoxyphenylacetamide

: 874-90-8
4-methoxybenzonitrile

Conditions

Conditions	Yield
With thionyl chloride; carbonic acid dimethyl ester at 80℃; for 7h; Temperature;	99.2%
With trichloromethyl chloroformate In various solvent(s) 0-5 deg C then heated to 60 deg C, 5 min;	97%
With ((1,3,5-triazine-2,4,6-triyl)tris(oxy))tris(triphenylphosphonium) chloride at 140 - 150℃; for 2h;	97%

: 3424-93-9
4-methoxyphenylacetamide

: 100-52-7
benzaldehyde

: 824-79-3
sodium 4-methylbenzenesulfinate

: 4-methoxy-N-[phenyl-(toluene-4-sulfonyl)-methyl]-benzamide

Conditions

Conditions	Yield
With chloro-trimethyl-silane In acetonitrile at 10 - 20℃; for 24h; Inert atmosphere;	99%
With chloro-trimethyl-silane In acetonitrile at 23℃;
With chloro-trimethyl-silane In acetonitrile at 0 - 20℃; Inert atmosphere;

...Expand

: 3424-93-9
4-methoxyphenylacetamide

: triethyl((3-ethylpent-3-yl)peroxy)silane

: 7403-41-0
N-ethyl-4-methoxy-benzamide

Conditions

Conditions	Yield
With copper(l) iodide; 1,10-Phenanthroline In benzene at 60℃; for 11h; Inert atmosphere;	99%
With copper(l) iodide; 1,10-Phenanthroline In benzene at 60℃; for 11h; Inert atmosphere;	99%

: 3424-93-9
4-methoxyphenylacetamide

: 123-11-5
4-methoxy-benzaldehyde

: 109163-43-1
4-methoxy-N-(4-methoxybenzyl)benzamide

Conditions

Conditions	Yield
With carbon monoxide In diethyl ether at 150 - 160℃; under 30003 Torr; Sealed tube;	99%
With carbon monoxide; C14H10Ru(2+)C11H17O(1-)*F6P(1-) In diethyl ether at 150℃; under 22801.5 Torr; for 22h; Autoclave;	70%

: 3424-93-9
4-methoxyphenylacetamide

: 1566-42-3
p-anisidine urea

Conditions

Conditions	Yield
With [bis(acetoxy)iodo]benzene; ammonia In methanol at 0 - 20℃; for 2h; Temperature; Hofmann Rearrangement; Inert atmosphere;	99%

: 3424-93-9
4-methoxyphenylacetamide

: 624-31-7
4-tolyl iodide

: 39192-94-4
N-(p-methylphenyl)-p-methoxybenzamide

Conditions

Conditions	Yield
With 2-Phenyl-1,3,2-dioxaborinane In 1,4-dioxane at 115℃; for 30h; Inert atmosphere;	99%

: 3424-93-9
4-methoxyphenylacetamide

: 124-41-4
sodium methylate

: 14803-72-6
methyl N-(4-methoxyphenyl)carbamate

Conditions

Conditions	Yield
Stage #1: 4-methoxyphenylacetamide; sodium methylate In methanol at 20℃; for 0.25h; Stage #2: With bis(1,3-dimethyl-2-imidazolidinone) hydrotribromide In methanol for 4h; Hofmann Rearrangement; Reflux;	98%
With N-Bromosuccinimide In methanol for 0.166667h; Heating;	87%

: 941-91-3
3-bromo-1-methylquinolin-2(1H)-one

: 3424-93-9
4-methoxyphenylacetamide

: 4-methoxy-N-(1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)benzamide

Conditions

Conditions	Yield
With copper; potassium carbonate; N,N`-dimethylethylenediamine In toluene at 135℃; for 2h; Ullmann type reaction; Inert atmosphere;	98%
With caesium carbonate; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 100℃; for 10h;	95%
With palladium diacetate; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 100℃;
With palladium diacetate; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 100℃; for 10h; Inert atmosphere; Sealed tube;

: 67-56-1
methanol

: 3424-93-9
4-methoxyphenylacetamide

: 51-66-1
4-methoxyacetanilide

Conditions

Conditions	Yield
With 3-[4-(diacetoxyiodo)phenoxy]-1-propyl-N,N,N-trimethylammonium 4-methylbenzenesulfonate; potassium hydroxide In chloroform at 0 - 20℃; Hofmann Rearrangement; Inert atmosphere;	98%

: 3424-93-9
4-methoxyphenylacetamide

: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With samarium diiodide; water In tetrahydrofuran at 23℃; for 0.0833333h; Reagent/catalyst; Inert atmosphere; Schlenk technique; chemoselective reaction;	98%
With samarium diiodide; water; triethylamine In tetrahydrofuran at 23℃; for 18h; Inert atmosphere; chemoselective reaction;	92%
With C24H20ClN2OPRu; potassium tert-butylate; hydrogen In tetrahydrofuran at 110℃; under 10640.7 Torr; for 36h; Inert atmosphere; Schlenk technique;	82%

: 3424-93-9
4-methoxyphenylacetamide

: 814-75-5
3-bromo-butanone

: 124811-80-9
2-(4-methoxy-phenyl)-4,5-dimethyl-oxazole

Conditions

Conditions	Yield
With silver(I) trifluoromethoxide In ethyl acetate at 50℃; for 4h; Darkness;	98%

: 3424-93-9
4-methoxyphenylacetamide

: 3399-73-3
2-(1-cyclohexenyl)ethylamine

: N-(2-(cyclohex-1-en-1-yl)ethyl)-4-methoxybenzamide

Conditions

Conditions	Yield
With dmap; triethylamine In dichloromethane at 20℃;	98%

: 3424-93-9
4-methoxyphenylacetamide

: 70-11-1
α-bromoacetophenone

: 25205-87-2
2-(4-methoxyphenyl)-4-phenyloxazole

Conditions

Conditions	Yield
With silver(I) trifluoromethoxide In ethyl acetate at 50℃; for 4h; Reagent/catalyst; Temperature; Darkness;	97%
at 140℃; for 1h;	80%
With silver trifluoromethanesulfonate In ethyl acetate at 50℃; Inert atmosphere;	64%
Heating;

: 70-23-5
ethyl Bromopyruvate

: 3424-93-9
4-methoxyphenylacetamide

: 78979-61-0
ethyl 2-(4-methoxyphenyl)-1,3-oxazole-4-carboxylate

Conditions

Conditions	Yield
With silver hexafluoroantimonate In 1,2-dichloro-ethane at 90℃; for 2h; Inert atmosphere; Microwave irradiation;	97%
With silver hexafluoroantimonate In dichloromethane at 90℃; under 3750.38 Torr; for 1h; Sealed tube; Microwave irradiation;
In ethanol at 70℃; for 5h;
Stage #1: ethyl Bromopyruvate; 4-methoxyphenylacetamide With sodium hydrogencarbonate In tetrahydrofuran at 60℃; for 23h; Stage #2: With trifluoroacetic anhydride In tetrahydrofuran at 20℃; for 12h;

: 3424-93-9
4-methoxyphenylacetamide

: 24424-99-5
di-tert-butyl dicarbonate

: N,N-di-Boc-4-methoxybenzamide

Conditions

Conditions	Yield
With dmap In neat (no solvent) for 4h; Milling; chemoselective reaction;	97%
With dmap In acetonitrile at 20℃; for 15h; Inert atmosphere; Sealed tube;	90%
With dmap In acetonitrile at 20℃; for 15h;	86%

: 50-00-0
formaldehyd

: 3424-93-9
4-methoxyphenylacetamide

: 41125-75-1
5-(4-methoxy)phenyl-1,3,4-oxadiazol-2(3H)-one

Conditions

Conditions	Yield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; ammonium cerium (IV) nitrate; nickel diethyldithiocarbamate; N-fluorobis(benzenesulfon)imide; 1-butyl-methylpyrrolidinium bis(trifluoromethylsulfonyl)amide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide at 60℃; for 10h;	96.8%

: 674-82-8
4-methyleneoxetan-2-one

: 3424-93-9
4-methoxyphenylacetamide

: 77656-07-6
4-Methoxy-N-(3-oxo-butyryl)-benzamide

Conditions

Conditions	Yield
With Aliquat 336 In toluene for 10h; Heating;	96%
With chloro-trimethyl-silane; sodium iodide In acetonitrile for 2h; Ambient temperature;	90%
With chloro-trimethyl-silane; sodium iodide In acetonitrile for 2h; Ambient temperature;	89.5%

4-methoxybenzamide Chemical Properties

Product Name: 4-Methoxybenzamide
The MF of 4-Methoxybenzamide (3424-93-9) is C₈H₉NO₂.

The MW of 4-Methoxybenzamide (3424-93-9) is 151.16.
Synonyms of 4-Methoxybenzamide (3424-93-9): p-Anisamide ; p-Methoxybenzamide
Product Categories: Aromatic Carboxylic Acids,Anilides, Anhydrides & Salts
Form: white crystalline powder
Index of Refraction: 1.546
EINECS: 222-319-6
Density: 1.143 g/ml
Flash Point: 161.5 °C
Boiling Point: 295.8 °C
Melting Point: 164-167 °C
BRN: 1862847

4-methoxybenzamide Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mammal (species unspecified)	LD50	unreported	1gm/kg (1000mg/kg)		Pharmaceutical Chemistry Journal Vol. 28, Pg. 335, 1994.

4-methoxybenzamide Safety Profile

Safety information of 4-Methoxybenzamide (3424-93-9):
Risk Statements
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements
22 Do not breathe dust
24/25 Avoid contact with skin and eyes
WGK Germany 3
RTECS CV5466666

Product Name

4-Methoxybenzamide

Synthetic route

4-methoxybenzamide Chemical Properties

4-methoxybenzamide Toxicity Data With Reference

4-methoxybenzamide Safety Profile

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