Acetyl chloride

Molecular Structure of Acetyl chloride (CAS NO.75-36-5):

IUPAC Name: acetyl chloride
Empirical Formula: C₂H₃ClO
Molecular Weight: 78.4976
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 0
Polar Surface Area: 17.07Ų
Index of Refraction: 1.379
Molar Refractivity: 16.19 cm³
Molar Volume: 70 cm³
Surface Tension: 24.1 dyne/cm
Density: 1.12 g/cm³
Flash Point: 4.4 °C
Enthalpy of Vaporization: 28.98 kJ/mol
Boiling Point: 46 °C at 760 mmHg
Vapour Pressure: 342 mmHg at 25°C
EINECS: 200-865-6
Melting point: -112 °C
Storage temp: Store at RT
Sensitive: Moisture Sensitive
Merck: 14,85
BRN: 605303
Stability: Stability Highly flammable. Reacts violently with DMSO, water, lower alcohols, and amines to generate toxic fumes. May form an explosive mixture with air. Note low flash point. Incompatible with water, alcohols, amines, strong bases, strong oxidizing agents, most common metals
Product Categories: Pharmaceutical Intermediates; Organics; Nucleosides, Nucleotides & Related Reagents; Protecting Agents for Hydroxyl and Amino Groups; Protecting Agents, Phosphorylating Agents & Condensing Agents;Biochemistry; Organic Chemicals; Chemistry; A-B, Puriss p.a.; Analytical Reagents for General Use; Puriss p.a.; Essential Chemicals; Reagent Grade; Routine Reagents; Reagent Plus; Acid Halides; Carbonyl Compounds; Organic Building Blocks
InChI
InChI=1/C2H3ClO/c1-2(3)4/h1H3
Smiles
C(C)(=O)Cl

 Acetyl chloride (CAS NO.75-36-5) can be used as  a reagent for acetylation in the synthesis or derivatization of chemical compounds. Examples of acetylation reactions include acylation processes such as esterification (see below) and the Friedel-Crafts reaction).

 Acetyl chloride (CAS NO.75-36-5) also can be used as raw materials of organic synthesis, used in the production of pharmaceutical, pesticide, new plating complexing agent,acylation agent, as well as other various fine synthetic organic intermediates.

  Acetyl chloride (CAS NO.75-36-5) may  be synthesized from the catalytic carbonylation of methyl chloride.
  Acetyl chloride can also be synthesized by the reaction of acetic acid (CH₃COO-H) with thionyl chloride (O=SCl₂) under liberation of sulfur dioxide (SO₂).
  CH₃COO-H + O=SCl₂ → CH₃COCl + SO₂ + H-Cl

Reported in EPA TSCA Inventory.

Poison by inhalation. Moderately toxic by ingestion. A human systemic irritant by inhalation. Violent hydrolysis reaction with Water or steam produces heat, acetic acid, HCl, and other corrosive chlorides. May decompose during preparation. Dangerous fire hazard when exposed to heat or flame. Explosion hazard by spontaneous chemical reaction with dimethyl sulfoxide or ethanol. Also incompatible with PCl₃. When heated to decomposition it emits highly toxic fumes of phosgene and Cl^-. To fight fire, use CO₂ or dry chemical. See also Chlorides.
Hazard Codes: F,C
Risk Statements: 11-14-34
R11:Highly flammable. 
R14 :Reacts violently with water. 
R34:Causes burns.
Safety Statements: 9-16-26-45-1/2
S9:Keep container in a well-ventilated place. 
S16:Keep away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S1/2:Keep locked up and out of the reach of children.
RIDADR: UN 1717 3/PG 2
WGK Germany: 1
RTECS: AO6390000
F: 3
HazardClass: 3
PackingGroup: II
HS Code: 29159080

DOT Classification:  3; Label: Flammable Liquid, Corrosive

 Acetyl chloride , with CAS number of 75-36-5, can be called Acetyl chloride ; Acetic chloride ; Ethanoyl chloride ; 3-(2-methoxyethoxymethoxymethyl)-2,5,7,9-tetrathiabicyclo[4.3.0]non-10-ene-8-thione ; Acetic acid, chloride ; Cellulose,esters,acetate ; Acetyl chloride, 98+% . It is a colourless to light yellow liquid with a pungent.