-
Name
Acrivastine
- EINECS
- CAS No. 87848-99-5
- Article Data5
- CAS DataBase
- Density 1.17 g/cm3
- Solubility
- Melting Point 55.5-59.5°C(lit.)
- Formula C22H24N2O2
- Boiling Point 555.1 °C at 760 mmHg
- Molecular Weight 348.445
- Flash Point 289.5 °C
- Transport Information
- Appearance
- Safety
- Risk Codes R22; R43
-
Molecular Structure
-
Hazard Symbols
Xn,
Xi
- Synonyms 2-Propenoicacid, 3-[6-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-2-pyridinyl]-,(2E)- (9CI);2-Propenoic acid,3-[6-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-2-pyridinyl]-, (E,E)-;BW 0270C;BW 825C;BW A825C;Semprex;
- PSA 53.43000
- LogP 3.95320
Acrivastine Chemical Properties
Molecular structure of Acrivastine (CAS NO.87848-99-5) is:
Product Name: Acrivastine
CAS Registry Number: 87848-99-5
IUPAC Name: (E)-3-[6-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridin-2-yl]prop-2-enoic acid
Molecular Weight: 348.43816 [g/mol]
Molecular Formula: C22H24N2O2
XLogP3: 1.6
H-Bond Donor: 1
H-Bond Acceptor: 4
Surface Tension: 52.2 dyne/cm
Density: 1.17 g/cm3
Flash Point: 289.5 °C
Enthalpy of Vaporization: 88 kJ/mol
Boiling Point: 555.1 °C at 760 mmHg
Vapour Pressure: 3.72E-13 mmHg at 25°C
Classification Code: Antihistaminic ;Histamine Agents ;Histamine Antagonists ;Histamine H1 Antagonists, Non-Sedating ;Histamine H1 antagonists ;Neurotransmitter Agents
Acrivastine Uses
Acrivastine (CAS NO.87848-99-5) is used for the treatment of allergies and hay fever. It is a second-generation H1-receptor antagonist antihistamine and works by blocking H1 histamine receptors.It is sold under the brand name Benadryl Allergy Relief in the U.K. by Pfizer. It is the active ingredient in the Semprex brand. Semprex-D is also acrivastine based, but contains a decongestant, pseudoephedrine.
Acrivastine Specification
Acrivastine , its cas register number is 87848-99-5. It also can be called Semprex-D ; (E)-6-((E)-3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)-2-pyridineacrylic acid ; (E)-6-((E)-3-(1-Pyrrolidinyl-1-p-tolylpropenyl)-2-pyridinacrylsaeure ; 2-Propenoic acid, 3-(6-(1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-2-pyridinyl)-, (E,E)- ; Acrivastin ; Acrivastina ; Acrivastinum ; Semprex .
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