Aniline-2-sulfonic acid supplier

Name
Aniline-2-sulfonic acid
EINECS 201-810-9
CAS No. 88-21-1
Article Data79
CAS DataBase
Density 1.512 g/cm³
Solubility sparingly soluble in water
Melting Point 300 °C
Formula C₆H₇NO₃S
Boiling Point 363oC
Molecular Weight 173.192
Flash Point
Transport Information UN 2585 8/PG 3
Appearance light brown powder
Safety 26-36/37/39-45-28A
Risk Codes 34
Molecular Structure
Hazard Symbols C
Synonyms Benzenesulfonicacid, o-amino- (6CI,7CI,8CI);1-Aminobenzene-2-sulfonic acid;2-Aminobenzenesulfonic acid;2-Aminobenzenesulphonic acid;2-Aminophenylsulfonic acid;2-Anilinesulfonic acid;2-Sulfoaniline;Benzenesulfonic acid,2-amino-;Aniline-o-sulphonic acid;NSC 147;Orthanilic acid;o-Aminobenzenesulfonic acid;o-Aminophenylsulfonic acid;o-Sulfanilic acid;
PSA 88.77000
LogP 2.17750

Synthetic route

: 62-53-3
aniline

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With sodium hydrogen sulfate; sulfuric acid at 200℃; for 19h; Reagent/catalyst; Temperature;	99%
With chlorosulfonic acid; 1,1,2,2-tetrachloroethane

: 80-82-0
2-nitrobenzenesulfonic acid

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With hydrogen at 120℃; under 30003 - 37503.8 Torr; for 0.75h; Reflux;	97%
With Raney nickel at 90 - 120℃; under 6000.6 - 9750.98 Torr;	4200 kg

: 62-53-3
aniline

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 121-57-3
4-aminobenzene sulfonic acid

Conditions

Conditions	Yield
With chlorosulfonic acid In 1,2-dichloro-benzene at 135℃; for 1h; Product distribution; Kinetics; Mechanism; E(activ), oth. temperatures;	A 3.2% B 96.8%
With sulfur trioxide In 1,2-dichloro-ethane at 5℃; Rate constant; Thermodynamic data; Product distribution; oth. temperature, E(activ.), var. ratios of reactants;
With sulfuric acid In 1,2-dichloro-benzene at 180℃; Kinetics; Thermodynamic data; Equilibrium constant; variation of molar ratio and temperature, Ea, ΔGo, ΔHo, ΔSo;
With sulfuric acid In 1,2-dichloro-benzene at 24.9℃; Thermodynamic data; Mechanism; Activation Free Energy, Enthalpy, Entropy of sulfonation and desulfonation;

: 522-75-8
thioindigo

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With (2,2':6',2''-terpyridine)(pyridine-2-carboxylate)iron(II)chloride; sodium hydroxide In water; acetonitrile	95%

: 4875-10-9
2-nitrothiophenol

A: 1155-00-6
bis(2-nitrophenyl)disulfide

B: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With water In 1,4-dioxane at 87℃; for 8h;	A 7% B 87%
In 1,4-dioxane; water at 87℃; for 6.25h;	A 20.4% B 16.7%
With water In 1,4-dioxane at 81 - 87℃; Rate constant; Mechanism; Product distribution; various water conc; different reaction times;

: 95-16-9
1,3-Benzothiazole

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With chloramine-B; sodium hydroxide; palladium dichloride In water; acetonitrile at 80℃; pH=12;	85%
With [RuCl(P(C6H5)3)2(O(C6H4)NCH(C4H3N))]; sodium hydroxide In water; acetonitrile at 39.84℃; Kinetics; Concentration; Solvent; Temperature;

: 1126-34-7
3-amino-benzenesulfonic acid, monosodium salt

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 62-53-3
aniline

C: 121-57-3
4-aminobenzene sulfonic acid

Conditions

Conditions	Yield
With disodium hydrogenphosphate; sodium dihydrogenphosphate In methanol for 0.0166667h; Product distribution; Mechanism; Irradiation; effect of solvent and pH;	A 15.6% B 37.2% C 39.3%
With perchloric acid; NaH2PO4-Na2HPO4 buffer; sodium chloride In water for 0.0166667h; Product distribution; Mechanism; Irradiation;	A 2.80 % Turnov. B 6.43 % Turnov. C 7.02 % Turnov.

...Expand

: 3345-86-6
N-phenylsulfamic acid

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With sulfuric acid; acetic acid

: 1576-59-6
2-amino-5-bromobenzenesulfonic acid

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With phosphorus; hydrogen iodide at 110℃; im Druckrohr;
With sodium hydroxide; zinc

: 154117-60-9
4-bromo-3-sulfo-benzoic acid

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With ammonia at 180℃; im Rohr;

: 7669-54-7
2-nitrobenzenesulfenyl chloride

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With methanol
Multi-step reaction with 2 steps 1: water; chlorine 2: natrium carbonate / Ansaeuern mit Essigsaeure und Kochen mit Eisenpulver View Scheme

: 100-65-2
N-Phenylhydroxylamine

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With ethanol; sulfur dioxide
With sulfur dioxide; water

: 3306-62-5
2-AMINOBENZENESULFONAMIDE

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium nitrite

: 1694-92-4
2-Nitrobenzenesulfonyl chloride

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With sodium carbonate Ansaeuern mit Essigsaeure und Kochen mit Eisenpulver;
With potassium hydroxide anschliessend Erwaermen mit N2H4+H2O und Palladium/Kohle oder Raney-Nickel;

: 98-11-3
benzenesulfonic acid

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
man reduziert das bei der Nitrierung entstandene Isomerengemisch nach Zugabe von Magnesiumoxyd mit Eisen und Schwefelsaeure;

: 3768-55-6
N-trimethylsilylaniline

: 104184-87-4
chlorine ethoxysulfonate

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 3782-61-4
ethyl phenylamidosulfate

C: 732944-81-9
N-ethyl-N-phenylamidosulfate

D: dianilinium (4-sulfonatophenylamido)sulfate

Conditions

Conditions	Yield
With acetic acid 1) CH2Cl2, (-10)-(-15) deg C, 2 h; reflux, 3 h; 2) (-10)-(-15) deg C, 3 h; Multistep reaction. Further byproducts given;

...Expand

: 2424-53-5
aniline sulfate

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 121-47-1
3-aminobenzenesulfonic acid

C: 121-57-3
4-aminobenzene sulfonic acid

Conditions

Conditions	Yield
With sulfuric acid at 40℃; Product distribution; Rate constant; Thermodynamic data; var. temperature, var. reaction time, var. ratio of reagents, presence of tetrabisulfatoboric acid, ΔE(activ.);
With sulfuric acid at 180℃; for 7h; Thermodynamic data; Kinetics; Product distribution; ΔE(act.), various time, various temperature, various excess of H2SO4;
With sulfur trioxide; mercury(II) sulfate at 7.6℃; for 0.5h; Thermodynamic data; Mechanism; Product distribution; E(activ.), various temperature, SO3 and HgSO4 concentration;

...Expand

: 2424-53-5
aniline sulfate

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 121-57-3
4-aminobenzene sulfonic acid

Conditions

Conditions	Yield
In 1,2-dichloro-benzene at 180℃; for 0.5h; Rate constant; Thermodynamic data; Kinetics; other temperature (165 and 195 deg C), reaction time 7 h, activation energy;	A 3.9 % Spectr. B 96.1 % Spectr.
In 1,2-dichloro-benzene at 180℃; for 0.5h; Equilibrium constant; Mechanism; other temperature (165 and 195 deg C), reaction time 7 h;	A 3.9 % Spectr. B 96.1 % Spectr.
In 1,2-dichloro-benzene at 183℃; for 0.5h; Rate constant; Thermodynamic data; Kinetics; water removal, other solvent and temperature (p-chlorotoluene: 162 deg C, p-bromochlorobenzene: 196 deg C), reaction time 7 h;	A 3.8 % Spectr. B 96.2 % Spectr.

: 15790-84-8
sodium phenylsulfamate

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 121-47-1
3-aminobenzenesulfonic acid

C: 62-53-3
aniline

D: 121-57-3
4-aminobenzene sulfonic acid

Conditions

Conditions	Yield
In methanol for 0.0166667h; Product distribution; Irradiation;	A 22.2 % Chromat. B 5.1 % Chromat. C 27.0 % Chromat. D 39.4 % Chromat.
In methanol Product distribution; Mechanism; Irradiation; varying solvents;	A 22.0 % Chromat. B 5.1 % Chromat. C 27.0 % Chromat. D 39.4 % Chromat.

...Expand

: 542-16-5, 2424-53-5, 20305-50-4, 29961-02-2
dianilunium sulphate

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 121-47-1
3-aminobenzenesulfonic acid

C: 121-57-3
4-aminobenzene sulfonic acid

Conditions

Conditions	Yield
With sulfuric acid; mercury(II) sulfate at 60℃; for 1h; Title compound not separated from byproducts;	A 2.8 % Spectr. B 43.8 % Spectr. C 53.4 % Spectr.
With sulfuric acid; sulfur trioxide at 90℃; for 5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With sulfuric acid at 90℃; for 5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With sulfuric acid; mercury(II) sulfate at 60℃; for 1h; Product distribution; variation of reagent conc., time, temperature, and catalyst rate;	A 2.8 % Spectr. B 43.8 % Spectr. C 53.4 % Spectr.

...Expand

: 121-47-1
3-aminobenzenesulfonic acid

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 62-53-3
aniline

C: 121-57-3
4-aminobenzene sulfonic acid

Conditions

Conditions	Yield
In methanol for 0.0166667h; Irradiation;	A 15.6 % Turnov. B 37.2 % Turnov. C 39.3 % Turnov.

...Expand

: 62-53-3
aniline

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 121-47-1
3-aminobenzenesulfonic acid

C: 121-57-3
4-aminobenzene sulfonic acid

Conditions

Conditions	Yield
With sulfuric acid at 180℃; for 7h; Yield given. Yields of byproduct given;
With sulfuric acid; mercury(II) sulfate at 100℃; for 1h; Title compound not separated from byproducts;	A 2.4 % Spectr. B 32.0 % Spectr. C 65.6 % Spectr.
With sulfuric acid at 90℃; Kinetics; Rate constant; Thermodynamic data; other temp.(90 - 210 deg C); other conc.H2SO4 (80.06 - 99.71percent); E-activation;

...Expand

: anilinium butylamidosulfate

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 137-51-9
4-aminobenzene-1,3-disulfonic acid

C: aniline-2,6-disulfonic acid

D: 121-57-3
4-aminobenzene sulfonic acid

Conditions

Conditions	Yield
at 160℃; for 8h; Yield given. Yields of byproduct given;
at 160℃; for 8h; Product distribution; Mechanism; other di- and trimethylanilinium butylamidosulfates, var. temperatures;

...Expand

: 121-57-3
4-aminobenzene sulfonic acid

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 121-47-1
3-aminobenzenesulfonic acid

Conditions

Conditions	Yield
With sulfuric acid at 180℃; Title compound not separated from byproducts;
With sulfuric acid at 180℃; Rate constant; Kinetics; other temperatures; other conc. of H2SO4; E(activ.);
With sulfuric acid at 190℃; Product distribution; Rate constant; var. ratio of reactants, object of study - isomerization;
With sulfuric acid at 180℃; Thermodynamic data; Rate constant; E(excit.);

: 27489-27-6
<(2-Nitro-phenyl)sulfonyl>essigsaeure

: 88-21-1
2-amino-1-benzenesulfonic acid

Conditions

Conditions	Yield
With sodium hydroxide

: 7732-18-5
water

: 100-65-2
N-Phenylhydroxylamine

sulfur dioxide: sulfur dioxide

: 88-21-1
2-amino-1-benzenesulfonic acid

...Expand

: 7732-18-5
water

: 62-53-3
aniline

disodium mercury (II)-sulfite: disodium mercury (II)-sulfite

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 3345-86-6
N-phenylsulfamic acid

...Expand

: 60-29-7
diethyl ether

: 100-65-2
N-Phenylhydroxylamine

sulfur dioxide: sulfur dioxide

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 3345-86-6
N-phenylsulfamic acid

C: 542-16-5, 2424-53-5, 20305-50-4, 29961-02-2
dianilunium sulphate

D: 495-48-7
azoxybenzene

...Expand

: 62-53-3
aniline

H2SO4 (fuming): H2SO4 (fuming)

A: 88-21-1
2-amino-1-benzenesulfonic acid

B: 121-47-1
3-aminobenzenesulfonic acid

C: 121-57-3
4-aminobenzene sulfonic acid

Conditions

Conditions	Yield
at 0 - 95℃; beim Behandeln von Anilin-sulfat;

...Expand

: 88-21-1
2-amino-1-benzenesulfonic acid

: C6H8N2O3S*(x)H2O4S

Conditions

Conditions	Yield
Stage #1: 2-amino-1-benzenesulfonic acid With sodium nitrite In water at 30℃; Stage #2: With sodium sulfite In water at 100 - 120℃; Stage #3: With sulfuric acid In water at 130℃;	99.2%

: 88-21-1
2-amino-1-benzenesulfonic acid

: C6H8N2O3S*(x)ClH

Conditions

Conditions	Yield
Stage #1: 2-amino-1-benzenesulfonic acid With sodium nitrite In water at 30℃; Acidic conditions; Flow reactor; Stage #2: With sodium sulfite In water at 95 - 110℃; Stage #3: With hydrogenchloride In water at 130℃;	99.1%

: 88-21-1
2-amino-1-benzenesulfonic acid

: 20667-12-3
silver(l) oxide

: [Ag(2-aminobenzosulfonate)]

Conditions

Conditions	Yield
In water acid (2 mmol0 and Ag2O (1 mmol) stirred for 2 h; filtered, crystd. on slow evapn. overnight, elem. anal.;	96%

: 88-21-1
2-amino-1-benzenesulfonic acid

: bismuth(III) tert-butoxide

: Bi(3+)*3C6H6NO3S(1-)

Conditions

Conditions	Yield
In tetrahydrofuran at -78 - 20℃; Inert atmosphere;	96%

: 88-21-1
2-amino-1-benzenesulfonic acid

: 5977-14-0
acetoacetamido

: sodium (Z)-2-(2-(1-amino-1,3-dioxobutan-2-ylidene)hydrazineyl)benzenesulfonate

Conditions

Conditions	Yield
Stage #1: 2-amino-1-benzenesulfonic acid With sodium hydroxide; sodium nitrite In water at 0 - 5℃; for 0.0833333h; Stage #2: With hydrogenchloride In water at 0 - 5℃; for 0.5h; Stage #3: acetoacetamido With sodium acetate; sodium hydroxide In ethanol; water for 1h;	92%

: 88-21-1
2-amino-1-benzenesulfonic acid

: 612-31-7
2-sulfo-benzenediazonium-betaine

Conditions

Conditions	Yield
With sulfuric acid; sodium carbonate; sodium nitrite In water at -10℃; for 0.5h;	91%
With sodium hydroxide; sulfuric acid; sodium nitrite
With ethanol; mixture of gaseous nitrogen oxides

: 88-21-1
2-amino-1-benzenesulfonic acid

: sodium ortho-iodobenzenesulfonate

Conditions

Conditions	Yield
Stage #1: 2-amino-1-benzenesulfonic acid With toluene-4-sulfonic acid In acetonitrile for 0.166667h; Stage #2: With potassium iodide; sodium nitrite In water; acetonitrile at 10 - 20℃; for 1.16667h;	91%
Stage #1: 2-amino-1-benzenesulfonic acid With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 0.5h; Stage #2: With sodium iodide In water at 0 - 50℃; for 14h;	65%
Stage #1: 2-amino-1-benzenesulfonic acid With hydrogenchloride; sodium nitrite In water at 0℃; Stage #2: With sodium iodide In water at 0 - 50℃; for 14h;	60%

: 88-21-1
2-amino-1-benzenesulfonic acid

: 7087-68-5
N-ethyl-N,N-diisopropylamine

: 35037-73-1
1-isocyanato-4-trifluoromethoxy-benzene

: N-ethyl-N-isopropylpropan-2-aminium 2-(3-(4-(trifluoromethoxy)phenyl)ureido)benzenesulfonate

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 8h;	91%

...Expand

: 88-21-1
2-amino-1-benzenesulfonic acid

: 109-77-3
malononitrile

: 120814-56-4
2-(2-(dicyanomethylene)hydrazinyl)benzenesulfonic acid

Conditions

Conditions	Yield
Stage #1: 2-amino-1-benzenesulfonic acid With sodium hydroxide In water at 20℃; Stage #2: With hydrogenchloride; sodium nitrite In water at -0.16℃; for 1h; Stage #3: malononitrile With sodium acetate In ethanol; water at -0.16℃; for 1h; Japp-Klingemann reaction;	90%

: 88-21-1
2-amino-1-benzenesulfonic acid

: 104-12-1
p-chlorphenylisocyanate

: 7087-68-5
N-ethyl-N,N-diisopropylamine

: N-ethyl-N-isopropylpropan-2-aminium 2-(3-(4-chlorophenyl)ureido)benzenesulfonate

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 8h;	89%

...Expand

: 88-21-1
2-amino-1-benzenesulfonic acid

: CB 3GA

: C35H22N8O14S4(4-)*4Na(1+)

Conditions

Conditions	Yield
With sodium carbonate In water at 90℃; for 5h; pH=5 - 7;	88%

: 88-21-1
2-amino-1-benzenesulfonic acid

: sodium 2-azidobenzenesulfonate

Conditions

Conditions	Yield
Stage #1: 2-amino-1-benzenesulfonic acid With sulfuric acid; sodium nitrite In water at 0℃; for 0.5h; Stage #2: With sodium azide In water at 20℃; for 15h;	88%

: 88-21-1
2-amino-1-benzenesulfonic acid

: 2469-99-0
Cyanoaceton

: sodium 2-(2-(1-cyano-2-oxopropylidene)hydrazinyl)benzenesulfonate

Conditions

Conditions	Yield
Stage #1: 2-amino-1-benzenesulfonic acid With hydrogenchloride; sodium hydroxide; sodium nitrite In water at 0 - 5℃; for 1h; Stage #2: Cyanoaceton With sodium acetate; sodium hydroxide In ethanol; water at 0℃; Japp-Klingemann Hydrazone Synthesis;	86%

: 37859-25-9
2-naphthylacetyl chloride

: 88-21-1
2-amino-1-benzenesulfonic acid

: 7087-68-5
N-ethyl-N,N-diisopropylamine

: N-ethyl-N-isopropylpropan-2-aminium 2-(2-(naphthalen-2-yl)acetamido)benzenesulfonate

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 4h;	85%

...Expand

: 88-21-1
2-amino-1-benzenesulfonic acid

: 7087-68-5
N-ethyl-N,N-diisopropylamine

: 1548-13-6
p-trifluoromethyl-phenylisocyanate

: N-ethyl-N-isopropylpropan-2-aminium 2-(3-(4-(trifluoromethyl)phenyl)ureido)benzenesulfonate

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 8h;	85%

...Expand

: 88-21-1
2-amino-1-benzenesulfonic acid

: 34893-92-0
3,4-dichlorophenyl isocyanate

: 7087-68-5
N-ethyl-N,N-diisopropylamine

: N-ethyl-N-isopropylpropan-2-aminium 2-(3-(3,5-dichlorophenyl)ureido)benzenesulfonate

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 8h;	85%

...Expand

: 108-77-0
1,3,5-trichloro-2,4,6-triazine

: 88-21-1
2-amino-1-benzenesulfonic acid

: 90-20-0
4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid

: 1-amino-2-sulfonic acid-4-(3-amino-2,4,6-trimethyl-5-sulfoamidophenyl)anthraquinone monosodium salt

: C42H27ClN9O18S5(5-)*5Na(1+)

Conditions

Conditions	Yield
Stage #1: 1,3,5-trichloro-2,4,6-triazine; 1-amino-2-sulfonic acid-4-(3-amino-2,4,6-trimethyl-5-sulfoamidophenyl)anthraquinone monosodium salt In water at 0 - 5℃; for 4h; pH=4- 6.5; Stage #2: 4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid In water at 28 - 35℃; pH=3.5 - 4; Stage #3: 2-amino-1-benzenesulfonic acid Further stages;	84.23%

...Expand

: 88-21-1
2-amino-1-benzenesulfonic acid

: 159596-05-1
4-morpholino-2-naphthol

: sodium (Z)-2-{2-[4-morpholino-2-oxonaphthalen-1(2H)-ylidene]hydrazinyl}benzenesulfonate

Conditions

Conditions	Yield
Stage #1: 2-amino-1-benzenesulfonic acid With potassium carbonate In water Stage #2: With hydrogenchloride; sodium nitrite In water at 5 - 10℃; Stage #3: 4-morpholino-2-naphthol With sodium hydroxide In water for 0.5h; Cooling;	84%

: 88-21-1
2-amino-1-benzenesulfonic acid

: 135-19-3
β-naphthol

: sodium (Z)-2-{2-[4-morpholino-2-oxonaphthalen-1(2H)-ylidene]hydrazinyl}benzenesulfonate

Conditions

Conditions	Yield
Stage #1: 2-amino-1-benzenesulfonic acid With potassium carbonate In water Stage #2: With hydrogenchloride; sodium nitrite In water at 5℃; Stage #3: β-naphthol With sodium hydroxide In water for 0.5h; Cooling;	84%

: 88-21-1
2-amino-1-benzenesulfonic acid

: 874-60-2
4-methyl-benzoyl chloride

: 2-(4-methylbenzamido)benzenesulfonic acid

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 4h;	84%

: 88-21-1
2-amino-1-benzenesulfonic acid

: 5416-93-3
4-Methoxyphenyl isocyanate

: 7087-68-5
N-ethyl-N,N-diisopropylamine

: N-ethyl-N-isopropylpropan-2-aminium 2-(3-(4-methoxyphenyl)ureido)benzenesulfonate

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 8h;	84%

...Expand

: 88-21-1
2-amino-1-benzenesulfonic acid

: 24677-78-9
2,3-dihydroxybenzaldehyde

: 2-[(2,3-dihydroxyphenyl)methylideneamino]benzenesulfonic acid trihydrate

Conditions

Conditions	Yield
With water In methanol at 20℃; for 24h;	83%

: 88-21-1
2-amino-1-benzenesulfonic acid

: 63059-25-6
2-iodobenzenesulfonic acid

Conditions

Conditions	Yield
Stage #1: 2-amino-1-benzenesulfonic acid With sodium carbonate In water Stage #2: With sodium nitrite In water at 0℃; for 0.75h; Further stages;	82%
durch Diazotierung und Zersetzung der Diazoverbindung mit rauch.Jodwasserstoffsaeure;
With sulfuric acid Diazotization.Erwaermen des Reaktionsprodukts mit Kaliumjodid;

: 88-21-1
2-amino-1-benzenesulfonic acid

: 148-53-8
3-methoxy-2-hydroxybenzaldehyde

: 2-[(2-hydroxy-3-methoxyphenyl)methylideneamino]benzenesulfonic acid

Conditions

Conditions	Yield
In ethanol; water at 20℃; for 24h;	82%

Aniline-2-sulfonic acid Chemical Properties

The molecular structure of Aniline-2-sulfonic acid (CAS NO.88-21-1):

IUPAC Name: 2-Aminobenzenesulfonic acid
Molecular Weight: 173.18968 g/mol
Molecular Formula: C₆H₇NO₃S
Density: 1.512 g/cm³
Melting Point: 300 °C
Index of Refraction: 1.629
Molar Refractivity: 40.71 cm³
Molar Volume: 114.4 cm³
Surface Tension: 67.5 dyne/cm
Water Solubility: sparingly soluble
XLogP3: 0.4
H-Bond Donor: 2
H-Bond Acceptor: 4
Rotatable Bond Count: 1
Exact Mass: 173.014664
MonoIsotopic Mass: 173.014664
Topological Polar Surface Area: 80.4
Heavy Atom Count: 11
Canonical SMILES: C1=CC=C(C(=C1)N)S(=O)(=O)O
InChI: InChI=1S/C6H7NO3S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H,8,9,10)
InChIKey: ZMCHBSMFKQYNKA-UHFFFAOYSA-N
EINECS: 201-810-9
Product Categories: Intermediates of Dyes and Pigments

Aniline-2-sulfonic acid Uses

Aniline-2-sulfonic acid (CAS NO.88-21-1) is used as dyes intermediates.

Aniline-2-sulfonic acid Toxicity Data With Reference

mma-sat 6667 µg/plate

EMMUEG Environmental and Molecular Mutagenesis. 11 (Suppl 12)(1988),1.

Aniline-2-sulfonic acid Consensus Reports

Reported in EPA TSCA Inventory.

Aniline-2-sulfonic acid Safety Profile

Hazard Codes: Corrosive C
Risk Statements: 34
R34:Causes burns.
Safety Statements: 26-36/37/39-45-28A
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S28:After contact with skin, wash immediately with plenty of soap-suds.
RIDADR: UN 2585 8/PG 3
WGK Germany: 3
RTECS: DB4727700
HazardClass: 8
PackingGroup: III

Aniline-2-sulfonic acid Specification

Aniline-2-sulfonic acid (CAS NO.88-21-1) is also named as 1-Aminobenzene-2-sulfonic acid ; 2-Aminobenzenesulfonic acid ; AI3-52212 ; Aniline-2-sulfonic acid ; Aniline-o-sulfonic acid ; Aniline-o-sulphonic acid ; Anilino-o-sulfonic acid ; Anilino-o-sulphonic acid ; CCRIS 4575 ; NSC 147 ; Orthanilic acid ; o-Aminobenzenesulfonic acid ; o-Aminophenylsulfonic acid ; o-Sulfanilic acid . Aniline-2-sulfonic acid (CAS NO.88-21-1) is light brown powder. It is soluble in water. Aniline-2-sulfonic acid is an amino acid. It reacts weakly with both acids and bases. Flash point data for Aniline-2-sulfonic acid are not available, however it is probably combustible.

Product Name

Aniline-2-sulfonic acid

Synthetic route

Aniline-2-sulfonic acid Chemical Properties

Aniline-2-sulfonic acid Uses

Aniline-2-sulfonic acid Toxicity Data With Reference

Aniline-2-sulfonic acid Consensus Reports

Aniline-2-sulfonic acid Safety Profile

Aniline-2-sulfonic acid Specification

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