Butyl glycolate supplier | CasNO.7397-62-8

Name
Butyl hydroxyacetate
EINECS 230-991-7
CAS No. 7397-62-8
Article Data20
CAS DataBase
Density 1.027 g/cm³
Solubility 46g/L at 20℃
Melting Point -26ºC
Formula C₆H₁₂O₃
Boiling Point 183 °C at 760 mmHg
Molecular Weight 132.159
Flash Point 71.7 °C
Transport Information
Appearance clear liquid
Safety 23-24/25
Risk Codes 63-41
Molecular Structure
Hazard Symbols Xn
Synonyms Aceticacid, hydroxy-, butyl ester (9CI);Glycolic acid, butyl ester (6CI,7CI,8CI);Butoxycarbonylmethanol;Butyl hydroxyacetate;Polysolvan O;n-Butyl glycolate;
PSA 46.53000
LogP 0.32200

Synthetic route

: 50-00-0
formaldehyd

: 201230-82-2
carbon monoxide

: 71-36-3
butan-1-ol

: 7397-62-8
butyl glycolate

Conditions

Conditions	Yield
Stage #1: formaldehyd; carbon monoxide With 1,3,5-Trioxan; formic acid; sulfuric acid In 1,4-dioxane; dichloromethane at 120℃; under 67506.8 Torr; Stage #2: butan-1-ol In 1,4-dioxane; dichloromethane at 160℃; under 18001.8 Torr; for 40h;	98.3%

...Expand

: 79-14-1
glycolic Acid

: 71-36-3
butan-1-ol

: 7397-62-8
butyl glycolate

Conditions

Conditions	Yield
With ion exchange at 120℃; pH=2; pH-value; Temperature; Reagent/catalyst;	92%
With toluene-4-sulfonic acid In cyclohexane for 5h; Reflux;	85.1%
With sulfuric acid; benzene bei langsamer Destillation;

: 502-97-6
glycolide

: 71-36-3
butan-1-ol

: 7397-62-8
butyl glycolate

Conditions

Conditions	Yield
stannous octoate In hexanoic acid at 135℃;

: 79-14-1
glycolic Acid

: 71-36-3
butan-1-ol

A: 502-97-6
glycolide

B: 7397-62-8
butyl glycolate

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In cyclohexane for 5h; Reflux;	A n/a B 85.1%

...Expand

: 50-00-0
formaldehyd

: 71-36-3
butan-1-ol

: 7397-62-8
butyl glycolate

Conditions

Conditions	Yield
With sulfuric acid; water at 210 - 260℃; under 588406 - 661957 Torr; CO-Druck;

: 109-65-9
1-bromo-butane

: 79-14-1
glycolic Acid

: 7397-62-8
butyl glycolate

Conditions

Conditions	Yield
With triethylamine for 1h; Heating; Inert atmosphere; Ionic liquid;	87%

: 131543-46-9
Glyoxal

: 71-36-3
butan-1-ol

: 7397-62-8
butyl glycolate

Conditions

Conditions	Yield
With zeolite MFI-ATSn for 6h; Reagent/catalyst; Time; Sealed tube; Green chemistry;	53%

: 71-36-3
butan-1-ol

ammonium glycolate: ammonium glycolate

A: 598-42-5
glycolamide

B: 7397-62-8
butyl glycolate

Conditions

Conditions	Yield
unter Entfernen des entstehenden Wassers und Ammoniaks;

...Expand

: 71-36-3
butan-1-ol

potassium chloroacetate: potassium chloroacetate

: 7397-62-8
butyl glycolate

: 7397-62-8
butyl glycolate

: 327-92-4
1,5-difluoro-2,4-dinitrobenzene

: 122641-49-0
butyl 2,4-dinitro-5-fluorophenoxyacetate

Conditions

Conditions	Yield
With triethylamine In 1,2-dichloro-ethane at 0 - 5℃; for 2h; Large scale;	89.9%

: 7397-62-8
butyl glycolate

: 590-02-3
butyl chloroacetate

Conditions

Conditions	Yield
With N,N-dimethyl-formamide; 2-Fluorobenzoyl chloride In 1,4-dioxane at 80℃; for 16h; Sealed tube;	75%

: 7397-62-8
butyl glycolate

: 624-83-9
methyl isocyanate

: 1182358-83-3
3-(hydroxymethyl)-4-methyl-1H-1,2,4-triazol-5(4H)-one

Conditions

Conditions	Yield
Stage #1: butyl glycolate With hydrazine hydrate at 50℃; for 1h; Stage #2: methyl isocyanate In water at -10 - 20℃; Stage #3: With sodium hydroxide In water at 95℃;	74%

: 271576-76-2
4-[3-(4-chlorophenyl)-4-piperidin-4-yl-1H-pyrazol-5-yl]pyrimidine

: 7397-62-8
butyl glycolate

: 271576-80-8
2-{4-[3-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-5-yl]piperidin-1-yl}-2-oxoethanol

Conditions

Conditions	Yield
With 1-methyl-pyrrolidin-2-one; 1,8-diazabicyclo[5.4.0]undec-7-ene at 110℃; for 3 - 3.41667h;	78%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In xylene; butan-1-ol at 25 - 145℃; Heating / reflux;

: 7397-62-8
butyl glycolate

: 95-50-1
1,2-dichloro-benzene

: n-butyl o-chlorophenoxyacetate

Conditions

Conditions	Yield
Stage #1: butyl glycolate With magnesium ethylate at 60℃; Stage #2: 1,2-dichloro-benzene at 90℃;	98.9%

: 7397-62-8
butyl glycolate

: 95-48-7
ortho-cresol

: n-butyl o-tolyloxyacetate

Conditions

Conditions	Yield
With Mo2P5-MCM-48 at 120℃; for 3h;	99.2%

: 79-41-4
poly(methacrylic acid)

: 7397-62-8
butyl glycolate

: methacrylic butyl glycolate ester

Conditions

Conditions	Yield
With 1,1'-carbonyldiimidazole In dichloromethane at 0 - 20℃;	20%

: 7397-62-8
butyl glycolate

: 108-95-2
phenol

: 32001-59-5
butyl 2-phenoxyacetate

Conditions

Conditions	Yield
With catalyst Mo2P5-MCM-48 (molar ratio of Mo2P5 and MCM-48: 25:100) at 100 - 120℃; for 2h; Reagent/catalyst; Time; Temperature;	65.78%

: 635725-14-3, 857729-86-3
4-[3-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-5-yl]cyclohexanone

: 7397-62-8
butyl glycolate

: 2-{4-[3-(4-chloro-2-fluorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-5-yl]piperidin-1-yl}-2-oxoethanol

Conditions

Conditions	Yield
Stage #1: 4-[3-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-5-yl]cyclohexanone; butyl glycolate With sodium ethanolate In ethanol at 20 - 81℃; for 4h; Stage #2: With hydrogenchloride In ethanol; water at 40℃; Product distribution / selectivity;	70%
Stage #1: 4-[3-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-5-yl]cyclohexanone; butyl glycolate With sodium ethanolate In ethanol at 20 - 81℃; for 4h; Stage #2: With hydrogenchloride; ethanol; water at 40℃; for 0.166667h;	70%
Stage #1: 4-[3-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-5-yl]cyclohexanone; butyl glycolate With 1,8-diazabicyclo[5.4.0]undec-7-ene In ethylene glycol at 80℃; for 4.9h; Nitrogen atmosphere; Stage #2: With water In ethylene glycol at 80℃; for 1.25h;

: 110-87-2
3,4-dihydro-2H-pyran

: 7397-62-8
butyl glycolate

: 2-(tetrahydropyran-2-yloxy)-acetic acid butyl ester

Conditions

Conditions	Yield
With hydrogenchloride; sodium hydrogencarbonate
With toluene-4-sulfonic acid In dichloromethane at 20 - 35℃; for 16.5h;

: 7397-62-8
butyl glycolate

: 115-11-7
isobutene

: 116193-68-1
n-butyl 2-tert-butoxyacetate

Conditions

Conditions	Yield
With sulfuric acid In dichloromethane at 25℃; for 72h;	68%
With sulfuric acid In dichloromethane

: 7397-62-8
butyl glycolate

: 6295-06-3
butyl glyoxalate

Conditions

Conditions	Yield
With (NH4)4[CuMo6O18(OH)6]·5H2O; oxygen; sodium sulfite In water; acetonitrile at 60℃; under 760.051 Torr; for 12h;	97%

: 7397-62-8
butyl glycolate

: 109-92-2
ethyl vinyl ether

: 213548-19-7
Vinyloxy-acetic acid butyl ester

Conditions

Conditions	Yield
With mercury(II) diacetate at 0℃; for 21h;	21%
With mercury(II) trifluoroacetate for 1h; Ambient temperature;	15%

: 7397-62-8
butyl glycolate

: 501-52-0
3-Phenylpropionic acid

: 3-phenyl-propionic acid butoxycarbonylmethyl ester

Conditions

Conditions	Yield
With N,N'-dimethylaminopyridine; di-tert-butyl dicarbonate In nitromethane at 50℃; for 16h;	91%

: 121592-85-6
3-chloro-2-(2,4-difluoro-5-nitrophenyl)-4,5,6,7-tetrahydro-2H-indazole

: 7397-62-8
butyl glycolate

: 121592-84-5
3-chloro-2-(2-fluoro-4-butyloxycarbonylmethoxy-5-nitrophenyl)-4,5,6,7-tetrahydro-2H-indazole

Conditions

Conditions	Yield
With potassium fluoride In 1,4-dioxane
With potassium fluoride In 1,4-dioxane

: 7397-62-8
butyl glycolate

: 76-83-5
trityl chloride

: 1449782-41-5
butyl 2-(trityloxy)acetate

Conditions

Conditions	Yield
With pyridine at 65℃; for 18h;	96%

: 5330-98-3
2-chloro-3-nitrothiophene

: 7397-62-8
butyl glycolate

: 2-(3-Nitro-2-thienyloxy)essigsaeurebutylester

Conditions

Conditions	Yield
With potassium carbonate In tetrahydrofuran at 40℃; for 48h;	84%

: 153577-85-6
3-(2,4-difluoro-5-nitrophenyl)-5-methyl-6-trifluoromethylpyrimidine-4-one

: 7397-62-8
butyl glycolate

: 3-(4-butoxycarbonylmethoxy-2-fluoro-5-nitrophenyl)-5-methyl-6-trifluoromethylpyrimidin-4-one

Conditions

Conditions	Yield
With potassium fluoride In 1,4-dioxane; ethyl acetate

: 7397-62-8
butyl glycolate

: 124-63-0
methanesulfonyl chloride

: n-butyl methylsulfonyloxyacetate

Conditions

Conditions	Yield
With triethylamine In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane

: 1-(2-chlorobenzyl)-4-chloro-5-formyl-2,3,6,7-tetrahydro-1H-azepine

: 7397-62-8
butyl glycolate

: Butyl 6-(2-chlorobenzyl)-5,6,7,8-tetrahydro-4H-furo[2,3-d]azepine-2-carboxylate

Conditions

Conditions	Yield
With nitrogen In 1,4-dioxane; chloroform; water; ethyl acetate

: 3238-40-2
furan-2,5-dicarboxylic acid

: 7397-62-8
butyl glycolate

: furandiformyl-butyl glycolate

Conditions

Conditions	Yield
With toluene-4-sulfonic acid at 160℃;

: 3265-14-3
3-diazo-1-methyl-1,3-dihydro-indol-2-one

: 7397-62-8
butyl glycolate

: butyl 2-((1-methyl-2-oxoindolin-3-yl)oxy)acetate

Conditions

Conditions	Yield
In dichloromethane at 25℃; for 24h; Irradiation;	56%

: 288-32-4
1H-imidazole

: 7397-62-8
butyl glycolate

: 18162-48-6
tert-butyldimethylsilyl chloride

: 114790-31-7
n-butyl <(tert-butyldimethylsilyl)oxy>acetate

Conditions

Conditions	Yield
In hexane
In hexane

...Expand

: 7397-62-8
butyl glycolate

: 70097-89-1
4-cyano-5-methyl-tetrahydrofuran-3-one

Conditions

Conditions	Yield
In tetrahydrofuran

Butyl glycolate Chemical Properties

IUPAC Name: Butyl 2-hydroxyacetate
Following is the structure of Acetic acid,2-hydroxy-, butyl ester (CAS NO.7397-62-8):

Empirical Formula: C₆H₁₂O₃
Molecular Weight: 132.1577
EINECS: 230-991-7
Index of Refraction: 1.429
Molar Refractivity: 33.15 cm³
Molar Volume: 128.5 cm³
Density: 1.027 g/cm³
Flash Point: 71.7 °C
Surface Tension: 34.8 dyne/cm
Enthalpy of Vaporization: 48.8 kJ/mol
Boiling Point: 183 °C at 760 mmHg
Appearance of Acetic acid,2-hydroxy-, butyl ester (CAS NO.7397-62-8): clear liquid
Vapour Pressure of Acetic acid,2-hydroxy-, butyl ester (CAS NO.7397-62-8): 0.227 mmHg at 25 °C
Canonical SMILES: CCCCOC(=O)CO
InChI: InChI=1S/C6H12O3/c1-2-3-4-9-6(8)5-7/h7H,2-5H2,1H3
InChIKey: VFGRALUHHHDIQI-UHFFFAOYSA-N

Butyl glycolate Safety Profile

Safety Statements: 23-24/25
S23:Do not breathe vapour.
S24/25:Avoid contact with skin and eyes.
WGK Germany: 1

Butyl glycolate Specification

Acetic acid,2-hydroxy-, butyl ester , its cas register number 7397-62-8. It also can be called Polysolvan 0 ; Butyl glycolate ; and Butyl hydroxyacetate .

Product Name

Butyl hydroxyacetate

Synthetic route

Butyl glycolate Chemical Properties

Butyl glycolate Safety Profile

Butyl glycolate Specification

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