Product Name

  • Name

    2-Bornanone

  • EINECS 200-945-0
  • CAS No. 76-22-2
  • Article Data196
  • CAS DataBase
  • Density 0.982 g/cm3
  • Solubility 0.12 g/100 mL (25 °C) in water
  • Melting Point 179 °C
  • Formula C10H16O
  • Boiling Point 207.4 °C at 760 mmHg
  • Molecular Weight 152.236
  • Flash Point 64.4 °C
  • Transport Information UN 2717 4.1/PG 3
  • Appearance Colourless solid
  • Safety 16-26-37/39
  • Risk Codes 11-22-36/37/38-20/21/22
  • Molecular Structure Molecular Structure of 76-22-2 (2-Bornanone)
  • Hazard Symbols FlammableF, HarmfulXn, IrritantXi
  • Synonyms 1,7,7-Trimethylbicyclo[2.2.1]-2-heptanone;1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one;2-Bornanone;Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-;2-Kamfanon;1,7,7-Trimethylnorcamphor;2-Camphanone;Bornane, 2-oxo-;DL-Camphor;Norcamphor, 1,7,7-trimethyl-;DL-Bornan-2-one;(+-)-Camphor;
  • PSA 17.07000
  • LogP 2.40170

Synthetic route

rac-endo-borneol
6627-72-1

rac-endo-borneol

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With tert.-butylhydroperoxide; chromium tetra(tert-butoxide) In benzene at 20℃; for 24h;100%
With peracetic acid; 2,4-dimethyl-2,4-pentanediol cyclic Cr(VI) ester In tetrachloromethane; dichloromethane at 0℃; for 12h;99%
With dimethyl sulfoxide; triethylamine; trichloromethyl chloroformate In dichloromethane92%
Conditions
ConditionsYield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; 3-[4'-(diacetoxyiodo)phenoxy]-1-propyl-N,N,N-trimethylammonium 4-methylbenzenesulfonate In dichloromethane at 20℃; for 12h;99%
With aluminum oxide; sodium bromite In dichloromethane for 24h; Ambient temperature;98%
With phosphomolybdic acid; oxygen; tetrabutylammonium acetate; palladium diacetate In toluene at 100℃; under 22502.3 Torr; for 16h; Solvent; Time;96%
With 1-methyl-1H-imidazole; tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate; 4,4'-Dimethoxy-2,2'-bipyridin; 9-azabicyclo[3.3.1]nonane N-oxyl; oxygen In acetonitrile at 70℃; for 1h;77%
With sodium dichromate; sulfuric acid for 3h; Heating;55.6%
isoborneol
24393-70-2

isoborneol

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With bis-trimethylsilanyl peroxide; dipyridinium dichromate In dichloromethane for 0.5h;98%
With dihydrogen peroxide; methyltrioctylammonium tetrakis(oxodiperoxotungsto)phosphate In 1,1,2,2-tetrachloroethylene at 90℃; for 0.75h;95%
With oxalyl dichloride; C4F9CH2CH2S(O)CH3 In dichloromethane at -30℃; Swern oxidation;94%
camphor ethanedithioketal
6787-91-3

camphor ethanedithioketal

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With ammonium iodide; dihydrogen peroxide; acetic acid In water at 20℃; for 1h;95%
Conditions
ConditionsYield
With tetraethylammonium bromate In ethanol for 3h; Heating;92%
With potassium permanganate; silica gel In water at 20℃; for 0.5h;80%
camphor oxime
18674-50-5

camphor oxime

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With dibromamine-B In tetrachloromethane at 20 - 25℃; for 0.333333h;90%
With N-iodo-succinimide; water In acetone for 0.05h; Microwave irradiation;87%
With water; oxygen In acetonitrile at 60℃; under 760.051 Torr; for 6h; Autoclave; Green chemistry;83%
With Oxone; silica gel In water; acetic acid at 25℃; for 24h;57%
1-bornenyl acetate
18529-99-2, 75524-60-6

1-bornenyl acetate

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With water; dichloro bis(acetonitrile) palladium(II) In isopropyl alcohol at 80℃; for 24h;87%
Conditions
ConditionsYield
With sodium hydrogen telluride In ethyl acetate for 1h; Ambient temperature;78%
3-exo-Bromocamphor
76-29-9

3-exo-Bromocamphor

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With water; zinc In acetonitrile at 80℃; for 11h; Inert atmosphere; Sealed tube;76%
With Methyltrichlorosilane; sodium iodide In acetonitrile for 18h; Heating;60%
1,7,7-trimethyl-2-nitrobicyclo[2.2.1]heptane

1,7,7-trimethyl-2-nitrobicyclo[2.2.1]heptane

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
Stage #1: 1,7,7-trimethyl-2-nitrobicyclo[2.2.1]heptane With potassium hydride In 1,4-dioxane at 10℃; for 1h;
Stage #2: With chloro-trimethyl-silane In 1,4-dioxane for 15h; Nef reaction; Heating; Further stages.;
62%
(+/-)-thiocampher
7519-74-6

(+/-)-thiocampher

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With clay supported cupric nitrate In dichloromethane Ambient temperature;30%
(+/-)-thiocampher
7519-74-6

(+/-)-thiocampher

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With sodium hydroxide; oxygen; rose bengal In chloroform Irradiation;A 30%
B 15%
With sodium hydroxide; oxygen; rose bengal In chloroform Rate constant; Mechanism; Irradiation;A 30%
B 15%
pyridine
110-86-1

pyridine

bornan-2-one-diethylacetal
52162-25-1

bornan-2-one-diethylacetal

acetyl chloride
75-36-5

acetyl chloride

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
-diethylacetal;
tetrachloromethane
56-23-5

tetrachloromethane

3-iodo-bornan-2-one
15736-81-9

3-iodo-bornan-2-one

sodium methylate
124-41-4

sodium methylate

A

4,7,7-trimethyl-3-oxo-norbornane-2-carbaldehyde
6812-07-3, 30543-79-4

4,7,7-trimethyl-3-oxo-norbornane-2-carbaldehyde

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
α-iodo-d-camphor;
tetrachloromethane
56-23-5

tetrachloromethane

rac-endo-borneol
6627-72-1

rac-endo-borneol

Camphor
76-22-2

Camphor

B

2,2-dimethyl-cyclopentane-1,1,3-tricarboxylic acid
6053-45-8

2,2-dimethyl-cyclopentane-1,1,3-tricarboxylic acid

Conditions
ConditionsYield
bei der Ozonisation;
diethyl ether
60-29-7

diethyl ether

3,3-diiodo-bornan-2-one

3,3-diiodo-bornan-2-one

sodium methylate
124-41-4

sodium methylate

A

4,7,7-trimethyl-3-oxo-norbornane-2-carbaldehyde
6812-07-3, 30543-79-4

4,7,7-trimethyl-3-oxo-norbornane-2-carbaldehyde

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
α.α'-diiodo-d-camphor;
rac-endo-borneol
6627-72-1

rac-endo-borneol

1,7,7-trimethyl bicyclo[2.2.1]heptan-2-ol
507-70-0

1,7,7-trimethyl bicyclo[2.2.1]heptan-2-ol

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With tetrachloromethane; chromic acid
With chromic acid; benzene
1,7,7-trimethyl bicyclo[2.2.1]heptan-2-ol
507-70-0

1,7,7-trimethyl bicyclo[2.2.1]heptan-2-ol

A

D-(+)-camphoric acid
124-83-4

D-(+)-camphoric acid

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With tetrachloromethane; ozone
1,7,7-trimethyl bicyclo[2.2.1]heptan-2-ol
507-70-0

1,7,7-trimethyl bicyclo[2.2.1]heptan-2-ol

dl-camphene
565-00-4

dl-camphene

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With copper at 135 - 140℃;
1,7,7-trimethyl bicyclo[2.2.1]heptan-2-ol
507-70-0

1,7,7-trimethyl bicyclo[2.2.1]heptan-2-ol

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
durch Erhitzen der Daempfe mit Sauerstoff oder Luft in Gegenwart von Kupfer;
With methyllithium; calcium carbonate durch Einw. von Metalloxyden oder Superoxyden;
With chlorine
1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one
736109-58-3, 787517-91-3

1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With aluminium trichloride; toluene at 80 - 85℃; Behandeln des Reaktiongemisches mit Wasser;
Conditions
ConditionsYield
With chromic acid; acetic acid at 140℃; <5-oxo-d-bornyl>-acetate;
d-borneol
464-43-7

d-borneol

dl-camphene
565-00-4

dl-camphene

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With nickel catalysts
With copper
d-borneol
464-43-7

d-borneol

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
at 300℃; beim Leiten ueber Kupfer;
Multi-step reaction with 2 steps
1: 145 °C
2: chromic acid; glacial acetic acid / 140 °C
View Scheme
4,7,7,4',7',7'-hexamethyl-[2,2']binorbornyl-3,3'-dione
25611-66-9

4,7,7,4',7',7'-hexamethyl-[2,2']binorbornyl-3,3'-dione

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
at 250℃; isodicamphor;
Camphor
76-22-2

Camphor

Conditions
ConditionsYield
at 205 - 210℃; α--quinone-hydrazone-(3);
2-carbethoxy-3-oxo-4,7,7-trimethylbicyclo<2,2,1>heptane
134234-71-2

2-carbethoxy-3-oxo-4,7,7-trimethylbicyclo<2,2,1>heptane

sodium ethanolate
141-52-6

sodium ethanolate

Camphor
76-22-2

Camphor

B

3-ethoxycarbonylmethyl-1,2,2-trimethyl-cyclopentanecarboxylic acid

3-ethoxycarbonylmethyl-1,2,2-trimethyl-cyclopentanecarboxylic acid

C

(3-ethoxycarbonyl-2,2,3-trimethyl-cyclopentyl)-acetic acid ethyl ester

(3-ethoxycarbonyl-2,2,3-trimethyl-cyclopentyl)-acetic acid ethyl ester

Conditions
ConditionsYield
at 200℃; im Autoklaven; d-camphocarboxylic acid ethyl ester;
2-iodo-4,7,7-trimethyl-3-oxo-norbornane-2-carbaldehyde

2-iodo-4,7,7-trimethyl-3-oxo-norbornane-2-carbaldehyde

sodium methylate
124-41-4

sodium methylate

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
<3-iodo-d-camphoryl-(3)>-formaldehyde;
2-nitrosohydroxylamino-2-cyano-camphane

2-nitrosohydroxylamino-2-cyano-camphane

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
at 160 - 170℃; das Silbersalz reagiert;
rac-endo-borneol
6627-72-1

rac-endo-borneol

A

D-(+)-camphoric acid
124-83-4

D-(+)-camphoric acid

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With tetrachloromethane; ozone
Conditions
ConditionsYield
With potassium 9-t-butyl-9-boratabicyclo<3.3.1>nonane In tetrahydrofuran at 0℃;99.9%
Camphor
76-22-2

Camphor

ethane-1,2-dithiol
540-63-6

ethane-1,2-dithiol

camphor ethanedithioketal
6787-91-3

camphor ethanedithioketal

Conditions
ConditionsYield
zinc trifluoromethanesulfonate In 1,2-dichloro-ethane for 15h; Heating;99%
With Cu(OTf)2-SiO2 In toluene at 80℃; for 60h;91%
With silica gel; toluene-4-sulfonic acid In dichloromethane for 24h; Heating;86%
With silica gel; zirconium(IV) chloride In dichloromethane for 72h; Ambient temperature;96 % Chromat.
2-methylbut-2-enal
497-03-0

2-methylbut-2-enal

Camphor
76-22-2

Camphor

(1S,4S)-3-((E)-1-Hydroxy-2-methyl-but-2-enyl)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one

(1S,4S)-3-((E)-1-Hydroxy-2-methyl-but-2-enyl)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one

Conditions
ConditionsYield
98%
Camphor
76-22-2

Camphor

acrolein
107-02-8

acrolein

(1S,4S)-3-(1-Hydroxy-allyl)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one

(1S,4S)-3-(1-Hydroxy-allyl)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one

Conditions
ConditionsYield
98%
trans-Crotonaldehyde
123-73-9

trans-Crotonaldehyde

Camphor
76-22-2

Camphor

(1S,4S)-3-((E)-1-Hydroxy-but-2-enyl)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one

(1S,4S)-3-((E)-1-Hydroxy-but-2-enyl)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one

Conditions
ConditionsYield
97%
Camphor
76-22-2

Camphor

camphor hydrazone

camphor hydrazone

Conditions
ConditionsYield
With hydrazine hydrate; acetic acid In ethanol for 24h; Reflux;97%
Camphor
76-22-2

Camphor

camphor oxime
18674-50-5

camphor oxime

Conditions
ConditionsYield
With hydroxylamine hydrochloride In ethanol for 4h; Mechanism; Reflux;94%
With hydroxylamine hydrochloride; sodium acetate In ethanol at 60℃; for 24h; Inert atmosphere;85%
With hydroxylamine hydrochloride; sodium hydroxide In ethanol; water at 20℃;73%
Camphor
76-22-2

Camphor

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
464-49-3

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

Conditions
ConditionsYield
94%
Multi-step reaction with 2 steps
1: sodium tetrahydroborate
2: borneol dehydrogenase 2 from Salvia officinalis L.; NAD / acetonitrile; water / 24 h / 20 °C / pH 8 / Resolution of racemate; Enzymatic reaction
View Scheme
Camphor
76-22-2

Camphor

(1S,4R)-3,3-Dibromo-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one

(1S,4R)-3,3-Dibromo-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one

Conditions
ConditionsYield
With N-Bromosuccinimide In chloroform; dimethyl sulfoxide at 25℃; for 240h; Mechanism; Darkness;94%
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

Camphor
76-22-2

Camphor

Conditions
ConditionsYield
With MDTBP In dichloromethane for 48h; Ambient temperature;93%
chloroform
67-66-3

chloroform

Camphor
76-22-2

Camphor

(E)-2-(chloromethylene)-1,7,7-trimethylbicyclo[2.2.1]heptane

(E)-2-(chloromethylene)-1,7,7-trimethylbicyclo[2.2.1]heptane

Conditions
ConditionsYield
With titanium tetrachloride; magnesium In tetrahydrofuran at 10 - 25℃; for 1h;92%
Camphor
76-22-2

Camphor

benzylamine
100-46-9

benzylamine

C17H23N

C17H23N

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 130℃; for 12h; Dean-Stark; Inert atmosphere;92%
Camphor
76-22-2

Camphor

1,8,8-trimethyl-2-oxabicyclo(3.2.1)oct-3-one
1126-91-6, 28973-92-4, 74867-81-5, 111056-61-2

1,8,8-trimethyl-2-oxabicyclo(3.2.1)oct-3-one

1,8,8-trimethyl-3-oxabicyclo(3.2.1)oct-2-one
507-96-0, 30860-35-6

1,8,8-trimethyl-3-oxabicyclo(3.2.1)oct-2-one

Conditions
ConditionsYield
With bis-trimethylsilanyl peroxide; 1-(n-butyl)-3-methylimidazolium triflate at 40℃; for 15h; Baeyer-Villiger oxidation; Ionic liquid; Inert atmosphere;A 89%
B n/a
With 3-chloro-benzenecarboperoxoic acid Yield given. Yields of byproduct given. Title compound not separated from byproducts;
Conditions
ConditionsYield
With water-d2; sodium In 1,4-dioxane at 50℃; for 168h;88%
Camphor
76-22-2

Camphor

oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

ethyl 2-(3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-en-2-yl)-2-oxoacetate

ethyl 2-(3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-en-2-yl)-2-oxoacetate

Conditions
ConditionsYield
With sodium hydride In toluene at 60℃; for 1h;88%
Camphor
76-22-2

Camphor

lithium 4-lithio-2-methyl-3-butyn-2-olate

lithium 4-lithio-2-methyl-3-butyn-2-olate

(+/-)-endo-2-(3-hydroxy-3-methyl-1-butynyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-exo-ol

(+/-)-endo-2-(3-hydroxy-3-methyl-1-butynyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-exo-ol

Conditions
ConditionsYield
In tetrahydrofuran at 20 - 23℃;81%
Camphor
76-22-2

Camphor

phenylacetylene
536-74-3

phenylacetylene

(+/-)-2-endo-(2-phenyl-1-ethynyl)-2-exo-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptane
124620-27-5

(+/-)-2-endo-(2-phenyl-1-ethynyl)-2-exo-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptane

Conditions
ConditionsYield
Stage #1: phenylacetylene With n-butyllithium In tetrahydrofuran; hexane at -40 - -20℃; for 1h;
Stage #2: Camphor In tetrahydrofuran; hexane at -20 - 20℃;
Stage #3: With water In tetrahydrofuran; hexane
80%
1,3-dehydroadamantane
24569-89-9

1,3-dehydroadamantane

Camphor
76-22-2

Camphor

A

1,1'-Biadamantane
3732-31-8

1,1'-Biadamantane

endo/exo-3-(1-adamantyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

endo/exo-3-(1-adamantyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

C

(1R,1'R,3R,3'R,4R,4'R)-3,3'-Bibornane-2,2'-dione

(1R,1'R,3R,3'R,4R,4'R)-3,3'-Bibornane-2,2'-dione

Conditions
ConditionsYield
at 100℃; for 5h; Inert atmosphere;A n/a
B 80%
C n/a
Camphor
76-22-2

Camphor

Trimethylenediamine
109-76-2

Trimethylenediamine

N,N’-(propane-1,3-diyl)bis(1,7,7-trimethylbicyclo[2.2.1]heptan-2-imine)

N,N’-(propane-1,3-diyl)bis(1,7,7-trimethylbicyclo[2.2.1]heptan-2-imine)

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 110℃;78%
methanol
67-56-1

methanol

Camphor
76-22-2

Camphor

d,l-camphor dimethyl acetal

d,l-camphor dimethyl acetal

Conditions
ConditionsYield
With trimethyl orthoformate at 20℃; for 24h;77%
Camphor
76-22-2

Camphor

ethyl iodide
75-03-6

ethyl iodide

phenylacetylene
536-74-3

phenylacetylene

(+/-)-2-endo-(2-phenyl-1-ethynyl)-2-exo-ethoxy-1,7,7-trimethylbicyclo[2.2.1]heptane

(+/-)-2-endo-(2-phenyl-1-ethynyl)-2-exo-ethoxy-1,7,7-trimethylbicyclo[2.2.1]heptane

Conditions
ConditionsYield
Stage #1: phenylacetylene With n-butyllithium In tetrahydrofuran; hexane at -40 - -20℃; for 1h;
Stage #2: Camphor In tetrahydrofuran; hexane at -20 - 20℃;
Stage #3: ethyl iodide In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane at 20℃; for 18h;
75%

Camphor History

In the 9th century, the Arab chemist, Al-Kindi, provided the earliest recipe for the production of camphor in his Kitab Kimiya' al-'Itr.
Already in the 19th century, it was known that with nitric acid, camphor could be oxidized into camphoric acid. Haller and Blanc published a semisynthesis of camphor from camphoric acid, which, although demonstrating its structure, would not prove it. In 1903,the first complete total synthesis for camphoric acid was published by Gustaf Komppa. 
In 1907, Komppa began industrial production of camphor in Tainionkoski, Finland.

Camphor Standards and Recommendations

OSHA PEL: TWA 2 mg/m3
ACGIH TLV: TWA 2 ppm; STEL 3 ppm; Not Classifiable as a Human Carcinogen
DFG MAK: 2 ppm (13 mg/m3)
DOT Classification:  4.2; Label: Flammable Solid

Camphor Analytical Methods

For occupational chemical analysis use NIOSH: Ketones II (desorption in 99:1 CS2:methanol) 1301.

Camphor Specification

The Camphor with CAS registry number of 76-22-2 is also known as Norcamphor, 1,7,7-trimethyl-. The IUPAC name is 4,7,7-Trimethylbicyclo[2.2.1]heptan-3-one. It belongs to product categories of Fine Chemical & Intermediates; Miscellaneous Natural Products; Ketone; Bicyclic Monoterpenes; Biochemistry; Camphor, etc. (Plasticizer); Functional Materials; Plasticizer; Terpenes. Its EINECS registry number is 200-945-0. In addition, the formula is C10H16O and the molecular weight is 152.23. This chemical is a colourless solid and should be stored in cool and dry place.

Physical properties about Camphor are: (1)ACD/LogP: 2.13; (2)ACD/LogD (pH 5.5): 2.13; (3)ACD/LogD (pH 7.4): 2.13; (4)ACD/BCF (pH 5.5): 24.39; (5)ACD/BCF (pH 7.4): 24.39; (6)ACD/KOC (pH 5.5): 342.47; (7)ACD/KOC (pH 7.4): 342.47; (8)#H bond acceptors: 1; (9)Index of Refraction: 1.485; (10)Molar Refractivity: 44.39 cm3; (11)Molar Volume: 154.8 cm3; (12)Surface Tension: 31.5 dyne/cm; (13)Density: 0.982 g/cm3; (14)Flash Point: 64.4 °C; (15)Enthalpy of Vaporization: 44.37 kJ/mol; (16)Boiling Point: 207.4 °C at 760 mmHg; (17)Vapour Pressure: 0.225 mmHg at 25 °C.

Preparation of Camphor: it is prepared by reaction of Turpentine. Camphene is obtained by the isomerization after pinene extraction. Then product is obtained by esterification, hydrolysis and dehydrogenation of camphen.

Uses of Camphor: it is used as chemical-based raw material and pharmaceutical intermediate. It is used to produce camphor-trimethylsilyl-enolether by reaction with chloro-trimethyl-silane. The reaction occurs with reagents NaI, triethylamine and solvents acetonitrile, pentane at ambient temperature for 96 hoursfor  hours. The yield is about 59%.

Camphor is used to produce camphor-trimethylsilyl-enolether by reaction with chloro-trimethyl-silane.

When you are using this chemical, please be cautious about it. As a chemical, it is irritating to eyes, respiratory system and skin. It is harmful by inhalation, in contact with skin and if swallowed. What's more, it is highly flammable. During using it, wear suitable protective clothing and eye/face protection. Keep away from sources of ignition. If contact with eyes accidently, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
1. Canonical SMILES: CC1(C2CCC1(C(=O)C2)C)C
2. InChI: InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3
3. InChIKey: DSSYKIVIOFKYAU-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intraperitoneal 400mg/kg (400mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
child LDLo unreported 100mg/kg (100mg/kg)   Yakkyoku. Pharmacy. Vol. 31, Pg. 1499, 1980.
child TDLo oral 51mg/kg (51mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
American Journal of Emergency Medicine. Vol. 7, Pg. 41, 1989.
dog LDLo oral 800mg/kg (800mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
frog LDLo subcutaneous 240mg/kg (240mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 50, Pg. 199, 1903.
infant LDLo oral 70mg/kg (70mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
American Journal of Pathology. Vol. 30, Pg. 857, 1954.
man LDLo unreported 29mg/kg (29mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
mouse LCLo inhalation 400mg/m3/3H (400mg/m3) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 22(11), Pg. 83, 1957.
mouse LD50 intraperitoneal 3gm/kg (3000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: REGIDITY

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
American Journal of Pathology. Vol. 30, Pg. 857, 1954.
mouse LD50 oral 1310mg/kg (1310mg/kg)   Shika Gakuho. Journal of Dentistry. Vol. 75, Pg. 934, 1975.
mouse LDLo subcutaneous 200mg/kg (200mg/kg) BEHAVIORAL: EXCITEMENT "Pharmakologische Prufung von Analgetika, Dissertation," Herrlen, G., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1933Vol. -, Pg. -, 1933.
rabbit LDLo oral 2gm/kg (2000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: REGIDITY
American Journal of Pathology. Vol. 30, Pg. 857, 1954.
rat LD50 subcutaneous 70mg/kg (70mg/kg)   "Ueber die Pharmakologische Wirkung eines dem Pentamethylentetrazol Vol. -, Pg. -, 1934.
rat LDLo intraperitoneal 900mg/kg (900mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 65, Pg. 275, 1939.

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