1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylic acid HCl monohydrate
ciprofloxacin hydrochloride
Conditions | Yield |
---|---|
In ethanol for 24 - 72h; Product distribution / selectivity; | 88% |
In iso-butanol for 2h; Product distribution / selectivity; | 88% |
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylic acid HCl monohydrate
water
Conditions | Yield |
---|---|
With 1,3-bis(dimethylamino)-2-propanol In ethanol; water High Pressure; Eu salt, ligand and 1,3-bis(dimethylamino)-2-propanol added to a mixt. of H2O and EtOH, stirred, placed in an autoclave, heated at 150°C for 48 h; crystd. for 1 wk; elem. anal.; | 47.2% |
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylic acid HCl monohydrate
water
Conditions | Yield |
---|---|
In water satd. aq. solns. ligand and HgCl2 were mixed in 2:1 ratio; ppt. was filtered off, dried in air; elem. anal.; |
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylic acid HCl monohydrate
Conditions | Yield |
---|---|
In water satd. aq. solns. ligand and CdCl2*2.5H2O were mixed in 2:1 ratio; ppt. was filtered off, dried in air; elem. anal.; |
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylic acid HCl monohydrate
Conditions | Yield |
---|---|
With HCl In hydrogenchloride solns. ligand and CdCl2*2.5H2O in concd. HCl were mixed in 1:1 ratio, mixt. was stand for several days; ppt. was filtered off, washed with acetone, dried in air; elem. anal.; |
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylic acid HCl monohydrate
Conditions | Yield |
---|---|
With HCl In hydrogenchloride solns. ligand and HgCl2 in concd. HCl were mixed in 1:1 ratio, mixt. wasstand for several days; ppt. was filtered off, washed with acetone, dried in air; elem. anal.; |
IUPAC Name: 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid hydrate hydrochloride
Molecular Formula: C17H18FN3O3.HCl.H2O
Molecular Weight: 385.82 g/mol
InChI: InChI=1/C17H18FN3O3.ClH.H2O/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;;/h7-10,19H,1-6H2,(H,23,24);1H;1H2
SMILES: N1CCN(CC1)c1c(F)cc2c(n(cc(c2=O)C(O)=O)C2CC2)c1.Cl.O
Classification Code: Antibacterial
Product Categories: Active Pharmaceutical Ingredients; Quinolones (Antibiotics for Research and Experimental Use); Antibiotics for Research and Experimental Use; Biochemistry; Antibiotic Explorer; Peptide Synthesis / Antibiotics
Flash Point: 305.6 °C
Enthalpy of Vaporization: 91.5 kJ/mol
Boiling Point: 581.8 °C at 760 mmHg
Melting Point: 318-320 °C
storage temperature: 0-6 °C
Vapour Pressure of Ciprofloxacin hydrochloride hydrate (CAS NO.86393-32-0): 2.24E-14 mmHg at 25 °C
Ciprofloxacin hydrochloride hydrate (CAS NO.86393-32-0), its Synonyms are 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, monohydrochloride, monohydrate ; Alcipro ; Belmacina ; Catex ; Cenin ; Ceprimax ; Ciprofloxacin HCl ; Ciprofloxacin hydrochloride ; Ciprofloxacin hydrochloride monohydrate .
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