Deoxycorticosterone acetate supplier

Name
Deoxycorticosterone acetate
EINECS 200-275-9
CAS No. 56-47-3
Article Data51
CAS DataBase
Density 1.14 g/cm³
Solubility insoluble in water
Melting Point 157 °C
Formula C₂₃H₃₂O₄
Boiling Point 504.1 °C at 760 mmHg
Molecular Weight 372.505
Flash Point 218 °C
Transport Information UN 2811
Appearance Off-white solid
Safety 22-24/25
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 11-Deoxycorticosterone,acetate (8CI);Pregn-4-ene-3,20-dione, 21-hydroxy-, acetate (7CI);11-Deoxycorticosterone 21-acetate;11-Desoxycorticosterone acetate;21-Acetoxy-3,20-diketopregn-4-ene;21-Acetoxypregn-4-en-3,20-dione;21-Acetoxypregn-4-ene-3,20-dione;21-Hydroxypregn-4-ene-3,20-dione 21-acetate;21-Hydroxypregn-4-ene-3,20-dione acetate;21-Hydroxyprogesterone 21-acetate;4-Pregnene-3,20-dione 21-acetate;4-Pregnene-3,20-dione-21-ol acetate;Arcort;Bio-Corten;Cortacet;Cortate;Cortenil;Cortesan;Cortexone acetate;Cortifar;Cortigen;Cortinaq;Cortiron;Cortivis;Cortixyl;DCA;DOC acetate;DOCA;Decorten;Decortin;Decosteron;Decosterone;Decostrate;Deoxycorticosterone21-acetate;Deoxycorticosterone acetate;Deoxycortone acetate;Descorterone;Descotone;Desoxycorticosterone acetate;Desoxycortone acetate;Dorcostrin;Doxo;Doxycamon;Krinocorts;NSC 9567;Ocriten;Ocritena;Percorten;Percotol;Primocort;Primocortan;Sincortex;Steraq;Syncort;Syncorta;Syncortyl;Unidocan;
PSA 60.44000
LogP 4.26670

Synthetic route

: 64-85-7
21-Hydroxyprogesterone

: 108-24-7
acetic anhydride

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With pyridine In benzene	89%
With pyridine
With pyridine Ambient temperature;
With pyridine

: 1171-90-0
3,20-dioxo-pregna-1,4-dien-21-yl acetate

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With thallium(III) nitrate trihydrate In diethylene glycol dimethyl ether for 24h; Ambient temperature;	25%

: 110-86-1
pyridine

: 934167-52-9
20ξ-hydroxy-3-oxo-pregnen-(4)-al-(21)

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
beim anschliessenden Behandeln mit Acetanhydrid;

: 463-51-4
Ketene

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With acetone
With acetone

: 56-23-5
tetrachloromethane

: 128-08-5
N-Bromosuccinimide

: 15086-91-6
24,24-diphenyl-chola-4,20(22)ξ,23-trien-3-one

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
Reaktion ueber mehrere Stufen;

...Expand

: 566-78-9
21-acetoxypregnenolone

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With aluminum tri-tert-butoxide; acetone
With chloroform; bromine Behandeln des erhaltenen Dibromids mit CrO3 in Essigsaeure und Behandeln einer Loesung des Reaktionsprodukts mit wss. CrCl2-Loesung unter Kohlendioxyd;
With chloroform; bromine Erwaermen des Reaktionsprodukts mit Zink-Pulver und Natriumacetat in Aether und anschliessend mit Essigsaeure und Erhitzen des danach isolierten Reaktionsprodukts mit Essigsaeure;
With chloroform; bromine Erwaermen des Reaktionsprodukts mit Zink-Pulver und Natriumacetat in Aether und anschliessend mit Essigsaeure und Erhitzen des danach isolierten Reaktionsprodukts mit Essigsaeure;

: 26987-64-4
21-chloropregn-4-ene-3,20-dione

: 127-09-3
sodium acetate

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With acetic acid

: 115098-53-8
21-acetoxy-3β-formyloxy-pregn-5-en-20-one

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With cyclohexanone; aluminum isopropoxide

: 20576-46-9
11-deoxy-21-iodocorticosterone

: 127-08-2
potassium acetate

: 56-47-3
deoxycorticosterone acetate

: 15086-91-6
24,24-diphenyl-chola-4,20(22)ξ,23-trien-3-one

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With tetrachloromethane; N-Bromosuccinimide unter Belichtung anschliessend des Reaktionsprodukts mit Kaliumacetat in Essigsaeure und Behandeln einer Loesung des danach isolierten Reaktionsprodukts in Essigsaeure und 1.2-Dichlor-aethan mit CrO3 in wss. Essigsaeure;

: 57-83-0
Progesterone

: 546-67-8
lead(IV) tetraacetate

: 64-19-7
acetic acid

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
at 75 - 85℃;

...Expand

: 111438-07-4
21-chloro-5β-pregnane-3,20-dione

: 64-19-7
acetic acid

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With bromine Erhitzen der Reaktionsloesung mit Kaliumacetat;
With bromine Erhitzen der Reaktionsloesung mit Kaliumacetat;

: 53892-00-5
21-Diazoprogesterone

: 64-19-7
acetic acid

: 56-47-3
deoxycorticosterone acetate

: 108-05-4
vinyl acetate

: 64-85-7
21-Hydroxyprogesterone

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With Candida antarctica lipase B In tetrahydrofuran at 45℃; Rate constant;

17-hydroxy-20ξ.21-diacetoxy-17βH-pregnen-(4)-one of mp: 162-163: 17-hydroxy-20ξ.21-diacetoxy-17βH-pregnen-(4)-one of mp: 162-163

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With toluene; zinc

17-hydroxy-20ξ.21-diacetoxy-17βH-pregnen-(4)-one of mp: 180-181: 17-hydroxy-20ξ.21-diacetoxy-17βH-pregnen-(4)-one of mp: 180-181

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With toluene; zinc

21-chloro-3β-hydroxy-pregnen-(5)-one-(20): 21-chloro-3β-hydroxy-pregnen-(5)-one-(20)

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
With chloroform; bromine Behandeln des Reaktionsprodukts mit CrO3 in Essigsaeure und Erwaermen des danach erhaltenen Reaktionsprodukts mit Natriumacetat und Essigsaeure, zuletzt unter Zusatz von Zink-Pulver;
With chloroform; bromine Behandeln des Reaktionsprodukts mit CrO3 in Essigsaeure und Erwaermen des danach erhaltenen Reaktionsprodukts mit Natriumacetat und Essigsaeure, zuletzt unter Zusatz von Zink-Pulver;

: 2402-25-7
21-acetoxy-5β-pregnane-3,20-dione

: 7726-95-6
bromine

: 64-19-7
acetic acid

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
und Erhitzen des Reaktionsprodukts mit Pyridin;
und Erhitzen des Reaktionsprodukts mit Kaliumacetat;
und Erhitzen des Reaktionsprodukts mit Kaliumacetat;

...Expand

: 7647-01-0
hydrogenchloride

: 64-17-5
ethanol

: 33439-96-2
3β.5.14.21-tetrahydroxy-3β.14β-pregnanone-(20)

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
Behand. des Reakt.pr. mit Acetanhydrid und Pyridin, Hydr.in Essigsaeure an Platin, Behand. mit CrO3 in Essigsaeure und Erhitzen mit Essigsaeure;

...Expand

: 566-78-9
21-acetoxypregnenolone

: 7726-95-6
bromine

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
Behandlung des erhaltenen Dibromids mit CrO3 in Essigsaeure und anschliessende Debromierung;
Behandlung des erhaltenen Dibromids mit CrO3 in Essigsaeure und anschliessende Debromierung;

: 853-27-0
3,20-dioxo-4-pregnen-21-al

: 64-19-7
acetic acid

zinc-powder: zinc-powder

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
Behandeln des Reaktionsprodukts mit Acetanhydrid und Pyridin;

...Expand

: 64-85-7
21-Hydroxyprogesterone

: 108-24-7
acetic anhydride

A: 56-47-3
deoxycorticosterone acetate

B: 115097-15-9
3,21-diacetoxy-pregna-3,5-dien-20-one

Conditions

Conditions	Yield
With toluene-4-sulfonic acid for 0.0833333h; microwave irradiation;

...Expand

: 104203-45-4
21-Benzoyloxy-4-pregnen-3,20-dion

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 67 percent / KHCO3 (saturated aq. sol.) / 3 h / Heating 2: 89 percent / pyridine / benzene View Scheme

: 104203-44-3
21-Benzoyloxy-4-pregnen-3,20-dion-3-ethylendithioacetal

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 76 percent / HgO, BF3-Et2O / tetrahydrofuran; H2O / Ambient temperature 2: 67 percent / KHCO3 (saturated aq. sol.) / 3 h / Heating 3: 89 percent / pyridine / benzene View Scheme

: 7150-18-7
3β-acetoxyetienic acid

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: benzene; thionyl chloride 2: diethyl ether / Behandeln des erhaltenen 3β-Acetoxy-21-diazo-pregnen-(5)-ons-(20) mit methanol. KOH 3: acetic acid 4: bromine; chloroform / Erwaermen des Reaktionsprodukts mit Zink-Pulver und Natriumacetat in Aether und anschliessend mit Essigsaeure und Erhitzen des danach isolierten Reaktionsprodukts mit Essigsaeure View Scheme

: 7429-97-2
3β-acetoxy-5-etienic acid chloride

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: diethyl ether / Behandeln des erhaltenen 3β-Acetoxy-21-diazo-pregnen-(5)-ons-(20) mit methanol. KOH 2: acetic acid 3: bromine; chloroform / Erwaermen des Reaktionsprodukts mit Zink-Pulver und Natriumacetat in Aether und anschliessend mit Essigsaeure und Erhitzen des danach isolierten Reaktionsprodukts mit Essigsaeure View Scheme

: 33769-71-0
21-diazo-3β-hydroxy-pregn-5-en-20-one

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: acetic acid 2: bromine; chloroform / Erwaermen des Reaktionsprodukts mit Zink-Pulver und Natriumacetat in Aether und anschliessend mit Essigsaeure und Erhitzen des danach isolierten Reaktionsprodukts mit Essigsaeure View Scheme
Multi-step reaction with 2 steps 1: acetone; aluminium tert-butylate; benzene / 14-stdg. bzw. 20-taegiges Behandeln bei Siedetemperatur bzw. bei Raumtemperatur View Scheme

: 57-83-0
Progesterone

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: iodine View Scheme
Multi-step reaction with 7 steps 2: benzene; toluene-4-sulfonic acid 3: pyridine 4: benzene; sodium ethylate; diethyl ether 5: ethanolic KOH 6: iodine / anschliessend Behandeln mit wss. KOH View Scheme
Multi-step reaction with 8 steps 2: benzene; toluene-4-sulfonic acid 3: pyridine 4: benzene; sodium ethylate; diethyl ether 5: aqueous acetic acid 7: iodine / anschliessend Behandeln mit wss. KOH View Scheme

: 911442-53-0
3β-hydroxypregn-5-ene-16,20-dione

: 56-47-3
deoxycorticosterone acetate

Conditions

Conditions	Yield
Multi-step reaction with 6 steps 2: toluene-4-sulfonic acid 5: palladium/charcoal; ethyl acetate / Hydrogenation 6: cyclohexanone; aluminium isopropylate View Scheme

: 56-47-3
deoxycorticosterone acetate

A: 303-01-5
21-hydroxy-5β-pregnane-3,20-dione

B: 111464-71-2
4,5-epoxy-21-hydroxypregnane-3,20-dione

Conditions

Conditions	Yield
With sodium hydroxide; 1-imidazolylsulfonylimidazolide; dihydrogen peroxide In tert-butyl alcohol for 3h;	A 29% B 62%
With sodium hydroxide; 1-imidazolylsulfonylimidazolide; dihydrogen peroxide In tert-butyl alcohol for 3h;	A 29% B 62%

: 56-47-3
deoxycorticosterone acetate

A: 567-02-2, 567-03-3, 800-10-2, 33995-21-0, 51548-31-3, 108450-73-3, 567-01-1
(3β,5α)-3,21-dihydroxypregnan-20-one

B: 298-36-2
5α-pregnan-21-ol-3,20-dione

Conditions

Conditions	Yield
In ethanol at 24 - 26℃; for 96h; Penicillium decumbens ATCC 10436, potato dextrose broth;	A 4% B 44%

: 50-00-0
formaldehyd

: 56-47-3
deoxycorticosterone acetate

: 100323-02-2
17β-(1(3)H-imidazol-4-yl)-androst-4-en-3-one

Conditions

Conditions	Yield
With ammonium hydroxide; copper diacetate In ethanol for 6h; Heating;	17%

: 108-22-5
Isopropenyl acetate

: 56-47-3
deoxycorticosterone acetate

: 115097-15-9
3,21-diacetoxy-pregna-3,5-dien-20-one

Conditions

Conditions	Yield
With toluene-4-sulfonic acid

: 74-90-8
hydrogen cyanide

: 56-47-3
deoxycorticosterone acetate

: 22-acetoxy-20-hydroxy-3-oxo-23,24-dinor-20ξH-chol-4-ene-21-nitrile

: 56-47-3
deoxycorticosterone acetate

: 64-85-7
21-Hydroxyprogesterone

Conditions

Conditions	Yield
With methanol; potassium hydrogencarbonate
With methanol; potassium carbonate

: 56-47-3
deoxycorticosterone acetate

: 1171-90-0
3,20-dioxo-pregna-1,4-dien-21-yl acetate

Conditions

Conditions	Yield
With selenium(IV) oxide; acetic acid; tert-butyl alcohol
mit Hilfe von Corynebacterium simplex;
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In benzene

: 56-47-3
deoxycorticosterone acetate

: 595-71-1
14,21-dihydroxy-pregn-4-ene-3,20-dione

Conditions

Conditions	Yield
mit Hilfe von Mucor griseo-cyanus;

: 56-47-3
deoxycorticosterone acetate

: 600-67-9
4-pregnen-11α,21-dionl-3,20-dione

Conditions

Conditions	Yield
mit Hilfe von Rhizopus nigricans;

: 56-47-3
deoxycorticosterone acetate

: 298-65-7
6β,21-dihydroxypregna-4-en-3,20-dione

Conditions

Conditions	Yield
mit Hilfe von Rhizopus arrhizus;

: 56-47-3
deoxycorticosterone acetate

: 80-92-2
pregnanediol

Conditions

Conditions	Yield
biochemische Umwandlung;

: 56-47-3
deoxycorticosterone acetate

: 22630-66-6
pregn-4-ene-3β,20βF,21-triol

Conditions

Conditions	Yield
With tetrahydrofuran; lithium aluminium tetrahydride; diethyl ether

: 56-47-3
deoxycorticosterone acetate

A: 16α,21-dihydroxy-5β-pregnane-3,20-dione

B: 601-39-8
16α,21-Dihydroxyprogesterone

Conditions

Conditions	Yield
mit Hilfe von Streptomyces argenteolus;

: 56-47-3
deoxycorticosterone acetate

: 112685-38-8
21-acetoxy-pregn-4-ene-3β,20βF-diol

Conditions

Conditions	Yield
With sodium tetrahydroborate

: 56-47-3
deoxycorticosterone acetate

: 640-39-1
9α,21-dihydroxyprogesterone

Conditions

Conditions	Yield
mit Hilfe von Mucor parasiticus;

: 56-47-3
deoxycorticosterone acetate

: 96346-36-0
21-acetoxy-6β-hydroxy-pregn-4-ene-3,20-dione

Conditions

Conditions	Yield
With Isopropenyl acetate; toluene-4-sulfonic acid anschliessende Umsetzung mit Monoperoxyphthalsaeure;

: 56-47-3
deoxycorticosterone acetate

: 114398-19-5
21-acetoxy-4β,5-dichloro-5α-pregnane-3,20-dione

Conditions

Conditions	Yield
With chlorine; propionic acid

: 56-47-3
deoxycorticosterone acetate

: 119076-63-0
21-acetoxy-3,3-dihydroperoxy-pregn-4-en-20-one

Conditions

Conditions	Yield
With diethyl ether; dihydrogen peroxide

: 56-47-3
deoxycorticosterone acetate

: 122703-58-6
4ξ,21-diacetoxy-5-hydroxy-5ξ-pregnane-3,20-dione

Conditions

Conditions	Yield
With osmium(VIII) oxide; dihydrogen peroxide folgende Umsetzung mit Acetanhydrid in Pyridin;

Deoxycorticosterone acetate Chemical Properties

Chemical Name: Deoxycorticosterone acetate
IUPAC NAME: [2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
CAS No.: 56-47-3
EINECS: 200-275-9
RTECS: HG0525000
RTECS Class: Tumorigen ; Reproductive Effector
Molecular Formula: C₂₃H₃₂O₄
Molecular Weight: 372.5 g/mol
Melting Point: 157°C
Density: 1.14 g/cm³
Flash Point: 218 °C
Boiling Point: 504.1 °C at 760 mmHg
Following is the structure of 11-Deoxycorticosterone acetate (56-47-3):

Product Categories about 11-Deoxycorticosterone acetate (56-47-3) are Biochemistry ; Hydroxyketosteroids ; Steroids
The chemical synonymous of 11-Deoxycorticosterone acetate (56-47-3) are 11-Deoxycorticosterone21-acetate ; 20-Dione,21-hydroxy-pregn-4-ene-acetate ; 21-Acetoxy-3,20-diketopregn-4-ene ; 21-Acetyloxypregn-4-ene-3,20-dione ; 21-Hydroxypregn-4-ene-3,20-dione21-acetate ; 4-Pregnene-3,20-dione-21-olacetate ; Arcort ; Bio-Corten

Deoxycorticosterone acetate Uses

11-Deoxycorticosterone acetate (56-47-3) is mainly used for biochemical studies and used as an adrenal cortex hormones drugs,it also has anti-inflammatory, anti-allergy effects.

Deoxycorticosterone acetate Safety Profile

Questionable carcinogen with experimental tumorigenic data. Experimental reproductive effects. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes.
Safety Statements about 11-Deoxycorticosterone acetate (56-47-3):
S22 Do not breathe dust.
S24/25: Avoid contact with skin and eyes.

Product Name

Deoxycorticosterone acetate

Synthetic route

Deoxycorticosterone acetate Chemical Properties

Deoxycorticosterone acetate Uses

Deoxycorticosterone acetate Safety Profile

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