Product Name

  • Name

    Bis(2-butoxyethyl)ether

  • EINECS 204-001-9
  • CAS No. 112-73-2
  • Article Data7
  • CAS DataBase
  • Density 0.888 g/cm3
  • Solubility Water Solubility :0.3 g/100 mL (20 °C)
  • Melting Point -60 °C(lit.)
  • Formula C12H26O3
  • Boiling Point 254.6 °C at 760 mmHg
  • Molecular Weight 218.337
  • Flash Point 117.2 °C
  • Transport Information
  • Appearance clear colorless to yellowish liquid
  • Safety 23-24/25
  • Risk Codes
  • Molecular Structure Molecular Structure of 112-73-2 (Bis(2-butoxyethyl)ether)
  • Hazard Symbols
  • Synonyms Ether,bis(2-butoxyethyl) (7CI,8CI);2,2'-Dibutoxyethyl ether;2-(2-Butoxyethoxy)-1-butoxyethane;2-Butoxyethyl ether;5,8,11-Trioxapentadecane;Bis(2-butoxyethyl) ether;DBDG;DibutylCarbitol;Hisolve BDB;Butane,1,1'-[oxybis(2,1-ethanediyloxy)]bis-;
  • PSA 27.69000
  • LogP 2.63640

Synthetic route

n-Butyl chloride
109-69-3

n-Butyl chloride

diethylene glycol
111-46-6

diethylene glycol

diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

Conditions
ConditionsYield
With sodium hydroxide; water; tetra(n-butyl)ammonium hydrogensulfate at 60℃; for 4h;97%
With perhydrodibenzo-18-crown-6; potassium hydroxide In water at 70℃; for 5h; Yield given;
1-chloro-hexan-3-ol
52418-81-2

1-chloro-hexan-3-ol

A

-butyl vinyl ether
111-34-2

-butyl vinyl ether

B

diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

Conditions
ConditionsYield
With sodium hydroxide
1-(2-bromoethoxy)butane
6550-99-8

1-(2-bromoethoxy)butane

A

-butyl vinyl ether
111-34-2

-butyl vinyl ether

B

diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

Conditions
ConditionsYield
With sodium hydroxide
3-oxa-1,5-dichloropentane
111-44-4

3-oxa-1,5-dichloropentane

sodium butanolate
2372-45-4

sodium butanolate

diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

Conditions
ConditionsYield
With butan-1-ol
3-oxa-1,5-dichloropentane
111-44-4

3-oxa-1,5-dichloropentane

butan-1-ol
71-36-3

butan-1-ol

diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

Conditions
ConditionsYield
With perhydrodibenzo-18-crown-6; potassium hydroxide In water Yield given;
1-bromo-butane
109-65-9

1-bromo-butane

diethylene glycol
111-46-6

diethylene glycol

diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

Conditions
ConditionsYield
With perhydrodibenzo-18-crown-6; potassium hydroxide In water at 70℃; for 5h; Yield given;
1-(2-bromoethoxy)butane
6550-99-8

1-(2-bromoethoxy)butane

sodium hydroxide

sodium hydroxide

A

-butyl vinyl ether
111-34-2

-butyl vinyl ether

B

diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

2-Butoxyethanol
111-76-2

2-Butoxyethanol

diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dimethylaniline; diethyl ether; PBr3
2: NaOH
View Scheme
1-bromo-butane
109-65-9

1-bromo-butane

Diethylene glycol monobutyl ether
112-34-5

Diethylene glycol monobutyl ether

diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

Conditions
ConditionsYield
With sodium hydride In toluene at 50℃;
diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

trityl azide
14309-25-2

trityl azide

N-(diphenylmethylidene)phenylamine
574-45-8

N-(diphenylmethylidene)phenylamine

Conditions
ConditionsYield
at 170 - 190℃; Rate constant;
diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

hydrogen bromide
10035-10-6, 12258-64-9

hydrogen bromide

1-bromo-butane
109-65-9

1-bromo-butane

diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

4-chloro-trityl azide
13189-73-6

4-chloro-trityl azide

x-chloro-benzophenone-phenylimine

x-chloro-benzophenone-phenylimine

Conditions
ConditionsYield
at 169.4℃; Rate constant;
at 179.8℃; Rate constant;
at 191℃; Rate constant;
diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

4-methyl-trityl azide
13189-72-5

4-methyl-trityl azide

x-methyl-benzophenone-phenylimine

x-methyl-benzophenone-phenylimine

Conditions
ConditionsYield
at 170℃; Rate constant;
at 180℃; Rate constant;
at 191℃; Rate constant;
diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

4-nitro-trityl azide
13189-74-7

4-nitro-trityl azide

x-nitro-benzophenone-phenylimine

x-nitro-benzophenone-phenylimine

Conditions
ConditionsYield
at 169.7℃; Rate constant;
at 179.8℃; Rate constant;
at 190.4℃; Rate constant;
diethylene glycol dibutyl ether
112-73-2

diethylene glycol dibutyl ether

ethyl 2-cyanoacrylate
7085-85-0

ethyl 2-cyanoacrylate

Co3(tris-(3-pyridyl)triazine)4(NCS)6

Co3(tris-(3-pyridyl)triazine)4(NCS)6

4C18H12N6*6CNS(1-)*3Co(2+)*2C6H7NO2*4C12H26O3

4C18H12N6*6CNS(1-)*3Co(2+)*2C6H7NO2*4C12H26O3

Conditions
ConditionsYield
Stage #1: Co3(tris-(3-pyridyl)triazine)4(NCS)6 In diethyl ether at 20℃; for 72h;
Stage #2: diethylene glycol dibutyl ether In diethyl ether at 20℃; under 2.8 Torr; Molecular sieve;
Stage #3: ethyl-2-cyanoacrilate at 4℃; for 48h; Inert atmosphere;

Diethylene glycol dibutyl ether Chemical Properties

MF: C12H26O3
MW: 218.33
EINECS: 204-001-9
mp:  -60 °C(lit.)
bp:  256 °C(lit.)
density:  0.885 g/mL at 25 °C(lit.)
vapor density:  >1 (vs air)
vapor pressure:  <0.01 mm Hg ( 20 °C)
refractive index:  n20/D 1.423(lit.)
Fp: 243 °F
Water Solubility:  0.3 g/100 mL (20 oC
Appearance: clear colorless to yellowish liquid
Product Categories: Functional Materials;Plasticizer;Polyalcohol Ethers, Esters (Plasticizer)
Synonyms: 1,1’-(oxybis(2,1-ethanediyloxy))bis-butan ; 1,1’-[oxybis(2,1-ethanediyloxy)]bis-butan ; 1,1’-[oxybis(2,1-ethanediyloxy)]bis-Butane ; 1-[2-(2-Butoxyethoxy)ethoxy]butane ; 2-(2-Butoxyethoxy)-1-butoxyethane ; 5,8,11-Trioxapentadecane ; Butane,1,1’-[oxybis(2,1-ethanediyloxy)]bis- ; Dibutylether diethylenglykolu 
The structure of  Diethylene glycol dibutyl (CAS NO.112-73-2) ether is:
 

 

Diethylene glycol dibutyl ether Uses

 Diethylene glycol dibutyl (CAS NO.112-73-2) can be used as solvent in electrochemistry, boracium chemistry and polymer, gas adsorption, extractant ,high boiling reaction medium, or used in fuel, lubricant,textile, medicine and pesticide.

Diethylene glycol dibutyl ether Toxicity Data With Reference

1.    

skn-rbt 500 mg open MLD

    UCDS**    Union Carbide Data Sheet. (Industrial Medicine and Toxicology Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017) 4/21 ,1967.
2.    

eye-rbt 500 mg open

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 10 (1954),61.
3.    

orl-mus TDLo:16 g/kg (7-14D preg):REP

    EVHPAZ    EHP, Environmental Health Perspectives. Subseries of DHEW Publications. 57 (1984),141.
4.    

orl-rat LD50:3900 mg/kg

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 10 (1954),61.
5.    

skn-rbt LD50:4040 mg/kg

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 10 (1954),61.

Diethylene glycol dibutyl ether Consensus Reports

 Diethylene glycol dibutyl (CAS NO.112-73-2) is reported in EPA TSCA Inventory. Glycol ether compounds are on the Community Right-To-Know List.

Diethylene glycol dibutyl ether Safety Profile

Safety Statements: 23-24/25 
S23: Do not breathe vapour
S24/25: Avoid contact with skin and eyes
WGK Germany: 1
RTECS: KN0350000
HS Code: 29091900
Moderately toxic by ingestion. Mildly toxic by skin contact. Experimental reproductive effects. A skin and eye irritant.Combustible when exposed to heat or flame. To fight fire, use foam or alcohol foam. When heated to decomposition it emits acrid smoke and irritating fumes.

Diethylene glycol dibutyl ether Specification

1、Fire Fighting Measures 
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. 
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. 
2、Handling and Storage 
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. 
Storage: Store in a cool, dry place. Store in a tightly closed container. 

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