Dimethoxymethylphenylsilane supplier

Name
Dimethoxymethylphenylsilane
EINECS 221-192-4
CAS No. 3027-21-2
Article Data24
CAS DataBase
Density 0.97 g/cm³
Solubility
Melting Point 73-75 °C
Formula C₉H₁₄O₂Si
Boiling Point 199.5 °C at 760 mmHg
Molecular Weight 182.294
Flash Point 80.6 °C
Transport Information
Appearance colorless or yellowish transparent liquid
Safety 26-36
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Silane,dimethoxymethylphenyl- (6CI,7CI,8CI,9CI);Dimethoxymethylphenylsilane;Dimethoxyphenylmethylsilane;Methylphenyldimethoxysilane;NSC 93924;Phenylmethyldimethoxysilane;SM 2;SM 2 (silane);Z 6073;
PSA 18.46000
LogP 1.25840

Synthetic route

: 75-79-6
Methyltrichlorosilane

: 1185-55-3
Methyltrimethoxysilan

: 108-90-7
chlorobenzene

: 3027-21-2
dimethoxy(methyl)phenylsilane

Conditions

Conditions	Yield
Stage #1: Methyltrimethoxysilan; chlorobenzene With magnesium In tetrahydrofuran for 1h; Reflux; Stage #2: Methyltrichlorosilane; Methyltrimethoxysilan; chlorobenzene In tetrahydrofuran for 6.5h; Concentration; Reflux;	99.6%

...Expand

: 1185-55-3
Methyltrimethoxysilan

: 100-58-3
phenylmagnesium bromide

: 3027-21-2
dimethoxy(methyl)phenylsilane

Conditions

Conditions	Yield
In diethyl ether for 1h; Reflux;	95%

: 67-56-1
methanol

: 766-08-5
methylphenylsilane

: 3027-21-2
dimethoxy(methyl)phenylsilane

Conditions

Conditions	Yield
With C18H24N2O2Zn In neat (no solvent) at 20℃; for 0.5h; Solvent; Inert atmosphere;	92%
With air; hydrido(triphenylphosphine)copper(I) hexamer In benzene for 4.5h; Ambient temperature;	83%
With C30H48N8Zn2 In tetrahydrofuran-d8 at 25℃; for 0.166667h; Inert atmosphere;

: 108-86-1
bromobenzene

: 1185-55-3
Methyltrimethoxysilan

: 3027-21-2
dimethoxy(methyl)phenylsilane

Conditions

Conditions	Yield
Stage #1: bromobenzene With magnesium; methyl iodide In tetrahydrofuran for 0.1h; Inert atmosphere; Reflux; Large scale; Stage #2: Methyltrimethoxysilan In tetrahydrofuran at 90℃; for 6.3h; Inert atmosphere; Large scale;	90.2%
With sodium at 38℃; for 2h; Temperature; Reagent/catalyst;	80%

: 67-56-1
methanol

: 124-41-4
sodium methylate

: 149-74-6
dichloromethylphenylsilane

: 3027-21-2
dimethoxy(methyl)phenylsilane

Conditions

Conditions	Yield
With hydrogenchloride In water at 40 - 70℃; for 1h;	88.6%

...Expand

: 1185-55-3
Methyltrimethoxysilan

: 108-90-7
chlorobenzene

: 3027-21-2
dimethoxy(methyl)phenylsilane

Conditions

Conditions	Yield
With 15-crown-5; sodium at 38℃; for 2h; Temperature;	87%
Stage #1: chlorobenzene With magnesium In tetrahydrofuran for 1.5h; Inert atmosphere; Reflux; Large scale; Stage #2: With methyl iodide In tetrahydrofuran for 1h; Inert atmosphere; Heating; Large scale; Stage #3: Methyltrimethoxysilan In tetrahydrofuran at 90℃; for 7h; Inert atmosphere; Large scale;	67%

: 5931-17-9
1,3-bis(4-hydroxybutyl)tetramethyldisiloxane

: 3027-21-2
dimethoxy(methyl)phenylsilane

A: 67-56-1
methanol

B hydroxybutyl-terminated polymethylsiloxane with fifty percent phenyl content: hydroxybutyl-terminated polymethylsiloxane with fifty percent phenyl content

Conditions

Conditions	Yield
With hydrogenchloride In water for 4.5h; Heating / reflux;	A n/a B 100%

...Expand

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 328-57-4
methyldifluorophenylsilane

Conditions

Conditions	Yield
With sodium hexaflorophosphate In various solvent(s) at 200℃; for 0.75h;	98%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 1068-55-9
isopropylmagnesium chloride

: 40299-93-2
rac-isopropylmethoxymethylphenylsilane

Conditions

Conditions	Yield
In tetrahydrofuran; diethyl ether for 18h; Inert atmosphere; Reflux;	97%

: 111-87-5
octanol

: 3027-21-2
dimethoxy(methyl)phenylsilane

: (methoxy)(octoxy)(methyl)(phenyl)silane

Conditions

Conditions	Yield
With CBV600 at 110℃; for 0.0833333h; Temperature; Microwave irradiation; Inert atmosphere;	95.8%
With CBV600 at 80℃; for 0.0833333h; Temperature; Reagent/catalyst; Microwave irradiation;

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 1365801-87-1
1-oxo-1-methyl-4-ethyl-4-hydroxymethyl-2,6-dioxa-1-phosphacyclohexane

: C15H25O5PSi

Conditions

Conditions	Yield
In monoethylene glycol diethyl ether at 110℃; for 9h; Temperature; Solvent; Inert atmosphere;	95.2%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 1365801-87-1
1-oxo-1-methyl-4-ethyl-4-hydroxymethyl-2,6-dioxa-1-phosphacyclohexane

: methylphenylbis(1-oxo-1-methyl-4-ethyl-1-phospha-2,6-dioxacyclohexyl-4-methoxy)silane

Conditions

Conditions	Yield
With methoxybenzene; sodium hydroxide at 150℃; for 11h; Reagent/catalyst; Temperature;	92.7%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 824-11-3
ethriol phosphite

: methylphenylbis(1-oxo-1-methyl-4-ethyl-1-phospha-2,6-dioxacyclohexyl-4-methoxy)silane

Conditions

Conditions	Yield
With methyl p-toluene sulfonate In 1,2-dimethoxyethane at 150℃; for 15h; Concentration; Solvent; Reagent/catalyst; Temperature; Inert atmosphere;	90.5%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 824-11-3
ethriol phosphite

: C15H25O5PSi

Conditions

Conditions	Yield
With methyl p-toluene sulfonate In N,N-dimethyl-formamide at 140℃; for 14h; Solvent; Temperature; Concentration; Reagent/catalyst; Inert atmosphere;	90.3%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 90-11-9
1-Bromonaphthalene

: 3553-88-6, 16544-83-5, 16952-14-0, 18544-02-0
methoxy(methyl)(1-naphthyl)phenylsilane

Conditions

Conditions	Yield
Stage #1: 1-Bromonaphthalene With magnesium In tetrahydrofuran; diethyl ether Inert atmosphere; Stage #2: dimethoxy(methyl)phenylsilane In tetrahydrofuran; diethyl ether for 12h; Reflux; Inert atmosphere;	90%
With magnesium In tetrahydrofuran; diethyl ether; toluene for 13h; Reflux;	89%
With magnesium 1) ether+benzene+THF; 2) ether+benzene+THF; 55 deg C, 12 h.; Yield given. Multistep reaction;
With magnesium In tetrahydrofuran; toluene for 12h; Inert atmosphere; Reflux;

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 13315-17-8
4,4'-bis(dimethylsilyl)diphenyl ether

polymer, Mw 15.9 KDa, Mw/Mn 2.20; monomer(s): 4,4\-bis(dimethylsilyl)diphenyl ether; methylphenyldimethoxysilane: polymer, Mw 15.9 KDa, Mw/Mn 2.20; monomer(s): 4,4\-bis(dimethylsilyl)diphenyl ether; methylphenyldimethoxysilane

Conditions

Conditions	Yield
With tris(pentafluorophenyl)borate In toluene	89%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 71-36-3
butan-1-ol

: 15576-83-7
di(butoxy)(methyl)(phenyl)silane

Conditions

Conditions	Yield
With Amberlyst 15 at 100℃; for 0.333333h; Microwave irradiation; Inert atmosphere;	89%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 5467-58-3
1-bromo-4-methoxynaphthalene

: methoxy(4-methoxy-1-naphthyl)methylphenylsilane

Conditions

Conditions	Yield
at 80℃; for 15h; Grignard reaction;	88%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 556-82-1
3-methyl-2-buten-1-ol

: (methoxy)(3-methyl-2-butenoxy)(methyl)(phenyl)silane

Conditions

Conditions	Yield
With CBV780 at 23℃; for 0.0833333h; Time; Microwave irradiation;	86.3%
With CBV 780 at 23℃; for 0.0833333h; Temperature; Microwave irradiation;

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 71-36-3
butan-1-ol

: (methoxy)(butoxy)(methyl)(phenyl)silane

Conditions

Conditions	Yield
With CBV600 at 23℃; for 0.333333h; Reagent/catalyst; Temperature;	86.1%
With HSZ-320HOA at 110℃; for 0.0833333h; Reagent/catalyst; Temperature; Microwave irradiation;

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 16413-71-1
N,N-dimethyl(naphthalen-1-yl)methanamine

: 1-(8-(methoxy(methyl)(phenyl)silyl)naphthalen-1-yl)-N,N-dimethylmethanamine

Conditions

Conditions	Yield
Stage #1: N,N-dimethyl(naphthalen-1-yl)methanamine With n-butyllithium In diethyl ether at 0 - 20℃; for 24h; Inert atmosphere; Schlenk technique; Stage #2: dimethoxy(methyl)phenylsilane In diethyl ether at -50 - 20℃; for 24h; Inert atmosphere; Schlenk technique;	86%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 18156-74-6
1-(Trimethylsilyl)imidazole

: 1453266-13-1
1-[methoxy(methyl)phenylsilyl]-1H-imidazole

Conditions

Conditions	Yield
With aluminum isopropoxide Heating; Inert atmosphere;	85.7%

: 111-87-5
octanol

: 3027-21-2
dimethoxy(methyl)phenylsilane

: di(octoxy)(methyl)(phenyl)silane

Conditions

Conditions	Yield
With Amberlyst 15 at 100℃; for 0.333333h; Microwave irradiation; Inert atmosphere;	85%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 18290-96-5
3,5-dimethyl-1-(trimethylsilyl)-1H-pyrazole

: 1453266-14-2
1-[methoxy(methyl)phenylsilyl]-3,5-dimethyl-1H-pyrazole

Conditions

Conditions	Yield
With aluminum isopropoxide Heating; Inert atmosphere;	84.4%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 75-65-0
tert-butyl alcohol

: (methoxy)(tert-butoxy)(methyl)(phenyl)silane

Conditions

Conditions	Yield
With CBV780 at 70℃; for 0.25h; Concentration; Microwave irradiation;	84.2%
With CBV 780 at 70℃; for 0.25h; Concentration; Microwave irradiation;

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 108-24-7
acetic anhydride

: 17998-91-3
di(acetoxy)methyl(phenyl)silane

Conditions

Conditions	Yield
With CBV780 at 110℃; for 0.0833333h; Sealed tube; Microwave irradiation;	81%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 123-62-6
propionic acid anhydride

: methyl(phenyl)di(propanoyloxy)silane

Conditions

Conditions	Yield
With CBV780 at 110℃; for 0.5h; Sealed tube; Microwave irradiation;	81%

: 2488-01-9
1,4-bis(dimethylsilyl)benzene

: 3027-21-2
dimethoxy(methyl)phenylsilane

polymer, Mw 11.7 KDa, Mw/Mn 1.65; monomer(s): 1,4-bis(dimethylsilyl)benzene; methylphenyldimethoxysilane: polymer, Mw 11.7 KDa, Mw/Mn 1.65; monomer(s): 1,4-bis(dimethylsilyl)benzene; methylphenyldimethoxysilane

Conditions

Conditions	Yield
With tris(pentafluorophenyl)borate In toluene	80%

: 3027-21-2
dimethoxy(methyl)phenylsilane

: 123-62-6
propionic acid anhydride

: methyl(methoxy)(phenyl)(propanoyloxy)silane

Conditions

Conditions	Yield
With CBV780 at 25℃; for 0.25h; Sealed tube;	77%

Dimethoxymethylphenylsilane Consensus Reports

Reported in EPA TSCA Inventory.

Dimethoxymethylphenylsilane Specification

The Dimethoxymethylphenylsilane, with the CAS registry number 3027-21-2, has the systematic name of Benzene, (dimethoxymethylsilyl)-. Being a kind of colorless or yellowish transparent liquid, its product categories are including Organics; Dialkoxysilanes; Functional Materials; Si (Classes of Silicon Compounds); Silane Coupling Agents; Silane Coupling Agents (Intermediates); Si-O Compounds; Phenyl Silanes.

The characteristics of this chemical are as follows: (1)ACD/LogP: 3.82; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.82; (4)ACD/LogD (pH 7.4): 3.82; (5)ACD/BCF (pH 5.5): 473.63; (6)ACD/BCF (pH 7.4): 473.63; (7)ACD/KOC (pH 5.5): 2862.1; (8)ACD/KOC (pH 7.4): 2862.1; (9)#H bond acceptors: 2; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 18.46; (13)Index of Refraction: 1.475; (14)Molar Refractivity: 52.87 cm³; (15)Molar Volume: 187.6 cm³; (16)Polarizability: 20.96×10^-24 cm³; (17)Surface Tension: 26.1 dyne/cm; (18)Density: 0.97 g/cm³; (19)Flash Point: 80.6 °C; (20)Enthalpy of Vaporization: 41.79 kJ/mol; (21)Boiling Point: 199.5 °C at 760 mmHg; (22)Vapour Pressure: 0.48 mmHg at 25°C; (23)Exact Mass: 182.076306; (24)MonoIsotopic Mass: 182.076306; (25)Topological Polar Surface Area: 18.5; (26)Heavy Atom Count: 12; (27)Complexity: 129.

When you are dealing with this chemical, you should be cautious. For being a kind of chemical which is irritating to eyes, respiratory system and skin, it may also cause inflammation to the skin or other mucous membranes. Therefore, you should wear suitable protective clothing. And if in case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

In addition, you could convert the following datas into the molecular structure:
(1)Canonical SMILES: CO[Si](C)(C1=CC=CC=C1)OC
(2)InChI: InChI=1S/C9H14O2Si/c1-10-12(3,11-2)9-7-5-4-6-8-9/h4-8H,1-3H3
(3)InChIKey: CVQVSVBUMVSJES-UHFFFAOYSA-N

Below are the toxicity information of this chemical:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	680mg/kg (680mg/kg)		"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1234, 1986.
rat	LD50	oral	892mg/kg (892mg/kg)	BEHAVIORAL: FLUID INTAKE BEHAVIORAL: COMA	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 22(2), Pg. 50, 1978.

Product Name

Dimethoxymethylphenylsilane

Synthetic route

Dimethoxymethylphenylsilane Consensus Reports

Dimethoxymethylphenylsilane Specification

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