Epitestosterone supplier | CasNO.481-30-1

Name
Epitestosterone
EINECS 200-835-2
CAS No. 481-30-1
Article Data14
CAS DataBase
Density 1.12 g/cm³
Solubility
Melting Point 218-220oC
Formula C₁₉H₂₈O₂
Boiling Point 432.9 °C at 760 mmHg
Molecular Weight 288.43
Flash Point 184.7 °C
Transport Information
Appearance Off-white to pale yellow solid
Safety 22-36
Risk Codes 68
Molecular Structure
Hazard Symbols Xn
Synonyms Androst-4-en-3-one,17a-hydroxy- (8CI);17-Epitestosterone;17a-Hydroxyandrost-4-en-3-one;17a-Hydroxyandrost-4-ene-3-one;17a-Testosterone;17a-cis-Testosterone;4-Androstene-17a-ol-3-one;Androst-4-en-17a-ol-3-one;Isotestosterone;NSC 26499;Testosterone, cis-;cis-Testosterone;epi-Testosterone;
PSA 37.30000
LogP 3.87920

Synthetic route

: 36025-82-8
3-oxoandrost-4-en-17α-yl benzoate

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
With potassium hydroxide In methanol at 65℃; for 4h;	80%
With potassium hydroxide

: 958883-18-6
17-epitestosterone 2-(prenyloxymethyl)benzoate

A: 107-86-8
3,3-dimethyl acrylaldehyde

B: 481-30-1
epitestosterone

C: 38978-06-2
17-methyl-18-norandrosta-4,13(17)-dien-3-one

D: 17β-Methyl-18-norandrosta-4,13-dien-3-on

Conditions

Conditions	Yield
Stage #1: 17-epitestosterone 2-(prenyloxymethyl)benzoate With 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane; water at 20℃; for 6h; Stage #2: In dichloromethane at 20℃; for 24h; Further stages.;	A n/a B 30% C n/a D n/a

...Expand

: 63-05-8
Androstenedione

A: 58-22-0
testosterone

B: 481-30-1
epitestosterone

Conditions

Conditions	Yield
With sodium acetate at 60℃; Reduktion an Blei-Kathoden;

: 1963-03-7
androst-5-ene-3β,17α-diol

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
mit Hilfe von Actinomyces viridochromogenes;

: 51067-43-7
Androstene oxide

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
With manganese(IV) oxide; lithium aluminium tetrahydride

: 1425-09-8
3-oxoandrost-4-en-17α-yl acetate

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
With potassium hydroxide In methanol Heating; Yield given;

17α-acetoxy-androsten-(4)-one-(3): 17α-acetoxy-androsten-(4)-one-(3)

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
With potassium hydroxide

: C27H34O4

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: Yb(OTf)3H2O / CH2Cl2 / 7 h / 20 °C 2.1: 85 percent / triphenylphosphine; diisopropyl azodicarboxylate / tetrahydrofuran / 1 h / 65 °C 3.1: DDQ / CH2Cl2; H2O / 6 h / 20 °C 3.2: 30 percent / Yb(ONf)3xH2O / CH2Cl2 / 24 h / 20 °C View Scheme

: 58-22-0
testosterone

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: 85 percent / triphenylphosphine; diisopropyl azodicarboxylate / tetrahydrofuran / 1 h / 65 °C 2.1: DDQ / CH2Cl2; H2O / 6 h / 20 °C 2.2: 30 percent / Yb(ONf)3*xH2O / CH2Cl2 / 24 h / 20 °C View Scheme

: 850848-14-5
testosterone 2-(prenyloxymethyl)benzoate

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: DDQ / CH2Cl2; H2O / 6 h / 20 °C 2.1: Yb(OTf)3H2O / CH2Cl2 / 7 h / 20 °C 3.1: 85 percent / triphenylphosphine; diisopropyl azodicarboxylate / tetrahydrofuran / 1 h / 65 °C 4.1: DDQ / CH2Cl2; H2O / 6 h / 20 °C 4.2: 30 percent / Yb(ONf)3xH2O / CH2Cl2 / 24 h / 20 °C View Scheme

: 58-22-0
testosterone

<2,4,6-triiodo-phenoxy>-acetyl chloride: <2,4,6-triiodo-phenoxy>-acetyl chloride

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 100 percent / pyridine / 0.25 h / 0 - 20 °C 2: 76 percent / 18-crown-6 / benzene / 72 h / Heating 3: 5percent KOH / methanol / Heating View Scheme
Multi-step reaction with 3 steps 1: 100 percent / pyridine / 0.25 h / 0 - 20 °C 2: 76 percent / CsOAc, 18-crow-6 / benzene / 72 h / Heating 3: 5percent KOH / methanol / Heating View Scheme

: 182243-71-6
Chloro-methanesulfonic acid (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 76 percent / 18-crown-6 / benzene / 72 h / Heating 2: 5percent KOH / methanol / Heating View Scheme
Multi-step reaction with 2 steps 1: 76 percent / CsOAc, 18-crow-6 / benzene / 72 h / Heating 2: 5percent KOH / methanol / Heating View Scheme

: 1259-22-9
5-androstene-3β,17β-diol 3-acetate 17-p-toluene-δ-sulfonate

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: 44 percent / NaNO2 / dimethylsulfoxide / 1 h / 135 °C 2: 64 percent / pyridine / 20 h / Ambient temperature 3: 90 percent / conc. HCl / CHCl3; methanol / 64 h / Ambient temperature 4: 89 percent / aluminium isopropoxide / toluene; cyclohexanone / 0.75 h / Heating 5: 80 percent / 5percent KOH / methanol / 4 h / 65 °C View Scheme

: 853-23-6
prasterone acetate

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 7 steps 1: 99 percent / NaBH4 / methanol; ethyl acetate; CH2Cl2 / 1 h 2: pyridine / 72 h / 30 °C 3: 44 percent / NaNO2 / dimethylsulfoxide / 1 h / 135 °C 4: 64 percent / pyridine / 20 h / Ambient temperature 5: 90 percent / conc. HCl / CHCl3; methanol / 64 h / Ambient temperature 6: 89 percent / aluminium isopropoxide / toluene; cyclohexanone / 0.75 h / Heating 7: 80 percent / 5percent KOH / methanol / 4 h / 65 °C View Scheme

Yield

Multi-step reaction with 7 steps
1: 99 percent / NaBH4 / methanol; ethyl acetate; CH2Cl2 / 1 h
2: pyridine / 72 h / 30 °C
3: 44 percent / NaNO2 / dimethylsulfoxide / 1 h / 135 °C
4: 64 percent / pyridine / 20 h / Ambient temperature
5: 90 percent / conc. HCl / CHCl3; methanol / 64 h / Ambient temperature
6: 89 percent / aluminium isopropoxide / toluene; cyclohexanone / 0.75 h / Heating
7: 80 percent / 5percent KOH / methanol / 4 h / 65 °C
View Scheme

: 1639-43-6
androstenediol-3-acetate

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 6 steps 1: pyridine / 72 h / 30 °C 2: 44 percent / NaNO2 / dimethylsulfoxide / 1 h / 135 °C 3: 64 percent / pyridine / 20 h / Ambient temperature 4: 90 percent / conc. HCl / CHCl3; methanol / 64 h / Ambient temperature 5: 89 percent / aluminium isopropoxide / toluene; cyclohexanone / 0.75 h / Heating 6: 80 percent / 5percent KOH / methanol / 4 h / 65 °C View Scheme

: 40768-03-4
androst-5-ene-3β,17α-diyl 3-acetate 17-benzoate

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 90 percent / conc. HCl / CHCl3; methanol / 64 h / Ambient temperature 2: 89 percent / aluminium isopropoxide / toluene; cyclohexanone / 0.75 h / Heating 3: 80 percent / 5percent KOH / methanol / 4 h / 65 °C View Scheme

: 40768-04-5
3β-hydroxyandrost-5-en-17α-yl benzoate

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 89 percent / aluminium isopropoxide / toluene; cyclohexanone / 0.75 h / Heating 2: 80 percent / 5percent KOH / methanol / 4 h / 65 °C View Scheme

: 100428-85-1
17α-hydroxyandrost-5-en-3β-yl 3-acetate

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 64 percent / pyridine / 20 h / Ambient temperature 2: 90 percent / conc. HCl / CHCl3; methanol / 64 h / Ambient temperature 3: 89 percent / aluminium isopropoxide / toluene; cyclohexanone / 0.75 h / Heating 4: 80 percent / 5percent KOH / methanol / 4 h / 65 °C View Scheme

: 58-22-0
testosterone

A: 63-05-8
Androstenedione

B: 481-30-1
epitestosterone

Conditions

Conditions	Yield
With unidentified fungal species isolated from grinded corn In water at 37℃; for 1h; pH=7; aq. phosphate buffer; Microbiological reaction; Enzymatic reaction;

: 83-46-5
β-sitosterol

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction 2: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction 3: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction View Scheme
Multi-step reaction with 4 steps 1: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction 2: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction 3: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction 4: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction View Scheme

Yield

Multi-step reaction with 3 steps
1: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction
2: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction
3: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction
View Scheme

Multi-step reaction with 4 steps
1: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction
2: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction
3: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction
4: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction
View Scheme

: 63-05-8
Androstenedione

: 481-30-1
epitestosterone

Conditions

Yield

Multi-step reaction with 2 steps
1: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction
2: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction
View Scheme

: 897-06-3
Androsta-1,4-diene-3,17-dione

A: 63-05-8
Androstenedione

B: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction 2: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction View Scheme

: 897-06-3
Androsta-1,4-diene-3,17-dione

: 481-30-1
epitestosterone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction 2: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction 3: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction View Scheme

Yield

: 16029-98-4
trimethylsilyl iodide

: 481-30-1
epitestosterone

: (8R,9S,10R,13S,14S)-10,13-Dimethyl-3,17-bis-trimethylsilanyloxy-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene

Conditions

Conditions	Yield
With 1,4-dithio-erythritol; N-methyl-N-trimethylsilyl-2,2,2-trifluoroacetamide at 60℃; for 0.25h;	99%

: 481-30-1
epitestosterone

: 530-62-1
1,1'-carbonyldiimidazole

: 17α-(1H-Imidazol-1-yl)androst-4-ene-3,17-dione

Conditions

Conditions	Yield
In acetonitrile for 5h; Substitution; Heating;	95%

: 481-30-1
epitestosterone

: 112-13-0
n-decanoyl chloride

: 5721-91-5
3-oxoandrost-4-en-17α-yl decanoate

Conditions

Conditions	Yield
With pyridine Ambient temperature;	91%

: 64-18-6
formic acid

: 481-30-1
epitestosterone

: 43124-39-6
3-oxoandrost-4-en-17α-yl formate

Conditions

Conditions	Yield
With pyridine; acetic anhydride Ambient temperature;	90%

: 112-16-3
n-dodecanoyl chloride

: 481-30-1
epitestosterone

: 219296-38-5
3-oxoandrost-4-en-17α-yl dodecanoate

Conditions

Conditions	Yield
With pyridine Ambient temperature;	89%

: 481-30-1
epitestosterone

: 7β-hydroxyepitestosterone

Conditions

Conditions	Yield
With potassium dihydrogenphosphate; cytochrome P450 monooxygenase Lg-23 mutant at 25℃; for 20h; Enzymatic reaction; regioselective reaction;	82%

: 481-30-1
epitestosterone

: 112-64-1
tetradecanoyl chloride

: 219296-39-6
3-oxoandrost-4-en-17α-yl tetradecanoate

Conditions

Conditions	Yield
With pyridine Ambient temperature;	80%

: 481-30-1
epitestosterone

: 65-85-0
benzoic acid

: 36025-82-8
3-oxoandrost-4-en-17α-yl benzoate

Conditions

Conditions	Yield
With di-isopropyl azodicarboxylate; triphenylphosphine In toluene at 80℃; for 1h;	72%

: 481-30-1
epitestosterone

: 112-76-5
Stearoyl chloride

: 219296-40-9
3-oxoandrost-4-en-17α-yl octadecanoate

Conditions

Conditions	Yield
With pyridine Ambient temperature;	71%

: 481-30-1
epitestosterone

A: 571-24-4
5alpha-Androstane-17alpha-ol-3-one

B: 5692-03-5
5beta-Androstane-17alpha-ol-3-one

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In ethanol	A 13% B 67%
With hydrogen; Lindlar's catalyst In tetrahydrofuran for 2h;	A 11% B 66%
With hydrogen; palladium on activated charcoal In methanol	A 22 % Chromat. B 76 % Chromat.

: 481-30-1
epitestosterone

: 108-24-7
acetic anhydride

: 1425-09-8
3-oxoandrost-4-en-17α-yl acetate

Conditions

Conditions	Yield
With pyridine Ambient temperature;	62%

: 481-30-1
epitestosterone

: 79-03-8
propionyl chloride

: 58769-88-3
3-oxoandrost-4-en-17α-yl propionate

Conditions

Conditions	Yield
With pyridine Ambient temperature;	57%

: 481-30-1
epitestosterone

: 141-75-3
butyryl chloride

: 219296-35-2
3-oxoandrost-4-en-17α-yl butyrate

Conditions

Conditions	Yield
With pyridine for 6h; Ambient temperature;	55%

: 481-30-1
epitestosterone

: 81290-20-2
(trifluoromethyl)trimethylsilane

: (8R,9S,10R,13S,14S,17R)-10,13-dimethyl-17-(trifluoromethoxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

Conditions

Conditions	Yield
With potassium fluoride; 2-fluoropyridine; silver trifluoromethanesulfonate; Selectfluor In ethyl acetate at 20℃; for 12h; Glovebox; Inert atmosphere;	54%

: 481-30-1
epitestosterone

: 2528-61-2
Heptanoic acid chloride

: 315-37-7
3-oxoandrost-4-en-17α-yl heptanoate

Conditions

Conditions	Yield
With pyridine Ambient temperature;	53%

: 481-30-1
epitestosterone

: 761-01-3
triethylamine sulfur trioxide

: epitestosterone-17-sulfate triethylammoniumsalt

Conditions

Conditions	Yield
With pyridine at 20℃;	41%

: 481-30-1
epitestosterone

: 5856-11-1
5alpha-Androstane-3beta,17alpha-diol

Conditions

Conditions	Yield
With sodium In pentan-1-ol for 0.666667h; Heating;	7%
Multi-step reaction with 2 steps 1: 13 percent / hydrogen / 10percent Pd/C / ethanol 2: 20 percent / hydrogen / platinum / acetic acid View Scheme

: 481-30-1
epitestosterone

: 98-59-9
p-toluenesulfonyl chloride

: 493036-62-7
17α-(toluene-4-sulfonyloxy)-androst-4-en-3-one

: 357-83-5
N-(2-chloro-1,1,2-trifluoroethyl)diethylamine

: 481-30-1
epitestosterone

: 3-Oxo-androst-4-en-17α-yl-chlorfluoracetat

Conditions

Conditions	Yield
In tetrahydrofuran

: 481-30-1
epitestosterone

: 17β-Methyl-18-norandrosta-4,13-dien-3-on

Conditions

Conditions	Yield
With N-(2-chloro-1,1,2-trifluoroethyl)diethylamine In tetrahydrofuran
Multi-step reaction with 2 steps 1: pyridine / 0 °C 2: Zn(OAc)2 / dioxane / 8 h / 90 °C View Scheme
Multi-step reaction with 2 steps 1: pyridine / 0 °C 2: Zn(OAc)2 / dioxane / 24 h / 90 °C View Scheme

: 481-30-1
epitestosterone

: 13α-Fluor-17β-methyl-18-norandrosten-(4)-on-(3)

Conditions

Conditions	Yield
With N-(2-chloro-1,1,2-trifluoroethyl)diethylamine In tetrahydrofuran

: 481-30-1
epitestosterone

: 63-05-8
Androstenedione

Conditions

Conditions	Yield
reaction with green cell suspension culture of Marchantia polymorpha;

: 481-30-1
epitestosterone

: 4579-56-0
Epitestosterone sulfate

Conditions

Conditions	Yield
With propylene glycol; human adrenal hydroxysteroid sulfotransferase (EC 2.8.2.2); PAPS for 0.166667h; Kinetics;

: 481-30-1
epitestosterone

: 18162-48-6
tert-butyldimethylsilyl chloride

: 70419-25-9
(8R,9S,10R,13S,14S,17R)-17-(tert-Butyl-dimethyl-silanyloxy)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

Conditions

Conditions	Yield
With 1H-imidazole In N,N-dimethyl-formamide Ambient temperature;

: 481-30-1
epitestosterone

: epitestosterone

Conditions

Conditions	Yield
With potassium tert-butylate; tert-butyl alcohol

Epitestosterone Chemical Properties

Molecular Structure of Epitestosterone (CAS NO.481-30-1):

Molecular Formula: C₁₉H₂₈O₂
Molecular Weight: 288.4244
IUPAC Name: (8R,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Synonyms of Epitestosterone (CAS NO.481-30-1): (17-alpha)-17-Hydroxyandrost-4-en-3-one ; 17-Epitestosterone ; 17-alpha-Hydroxyandrost-4-en-3-one ; 17-alpha-Testosterone ; 17alpha-Hydroxyandrost-4-en-3-one ; 17alpha-Testosterone ; BRN 1915396 ; Isotestosterone ; NSC 26499 ; cis-Testosterone ; Androst-4-en-3-one, 17-alpha-hydroxy- ; Androst-4-en-3-one, 17-hydroxy-, (17-alpha)- (9CI) ; Androst-4-en-3-one, 17-hydroxy-, (17alpha)- ; Androst-4-en-3-one, 17alpha-hydroxy- (8CI)
CAS NO: 481-30-1
Classification Code: Hormone ; Reproductive Effect
Polar Surface Area: 26.3 Å²
Index of Refraction: 1.56
Molar Refractivity: 83.11 cm³
Molar Volume: 256.9 cm³
Surface Tension: 44.4 dyne/cm
Density of Epitestosterone (CAS NO.481-30-1): 1.12 g/cm³
Flash Point: 184.7 °C
Enthalpy of Vaporization: 79.52 kJ/mol
Boiling Point: 432.9 °C at 760 mmHg
Vapour Pressure: 2.6E-09 mmHg at 25°C

Epitestosterone Safety Profile

Hazard Codes of Epitestosterone (CAS NO.481-30-1): Harmful Xn
Risk Statements: 68
R68: Possible risk of irreversible effects.
Safety Statements: 22-36
S22: Do not breathe dust.
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: BV8395600

Product Name

Epitestosterone

Synthetic route

Epitestosterone Chemical Properties

Epitestosterone Safety Profile

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