• Name

  Ethyl 6,8-dichlorooctanoate

• EINECS 435-080-1
• CAS No. 1070-64-0
• Density 1.094 g/cm³
• Solubility
• Melting Point
• Formula C₁₀H₁₈Cl₂O₂
• Boiling Point 288.5 °C at 760 mmHg
• Molecular Weight 241.158
• Flash Point 105.1 °C
• Transport Information
• Appearance Colorless to yellowish transparent liquid
• Safety 26-36
• Risk Codes 36/37/38
• Molecular Structure
• Hazard Symbols Xi
• Synonyms 6,8-Dichlorooctanoicacid ethyl ester;
• PSA 26.30000
• LogP 3.34620

Synthetic route

1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

Conditions

Conditions	Yield
With phosgene; N,N'-dimethylbenzylamine In 1,2-dichloro-ethane at 10 - 75℃; for 2.5h; Concentration; Solvent; Reagent/catalyst; Temperature;	96.69%
With pyridine; thionyl chloride; benzene
With thionyl chloride In toluene at 100℃; for 5h; Reagent/catalyst; Solvent; Cooling with ice; Large scale;	480 kg

C10H20O4

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

Conditions

Conditions	Yield
With thionyl chloride at 80℃; for 4h; Reagent/catalyst; Temperature; Alkaline conditions;	87%

626-86-8

adipinic acid monoethyl ester

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1,1,2,2-tetrachloro-ethane; thionyl chloride / anschliessendes Behandeln mit Aethylen und Aluminiumchlorid und Behandeln der nach dem Versetzen mit wss.Salzsaeure erhaltenen nicht-waessrigen Phase des Reaktionsgemisches mit Natriumboranat in Aethanol 2: benzene; pyridine; thionyl chloride View Scheme

22054-13-3

7-hydroxyheptanal

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: Pt/γ-Al2O3 / toluene / 100 °C 2: alumina / 350 °C 3: Amberlyst-15 / 10 h / 100 °C 4: Pd/γ-Al2O3; hydrogen / water / 100 °C / 37503.8 Torr / Sealed tube 5: thionyl chloride / 4 h / 80 °C / Alkaline conditions View Scheme

6149-48-0

ethyl 7-hydroxyheptanoate

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: alumina / 350 °C 2: Amberlyst-15 / 10 h / 100 °C 3: Pd/γ-Al2O3; hydrogen / water / 100 °C / 37503.8 Torr / Sealed tube 4: thionyl chloride / 4 h / 80 °C / Alkaline conditions View Scheme

25118-23-4

ethyl 6-heptenoate

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: Amberlyst-15 / 10 h / 100 °C 2: Pd/γ-Al2O3; hydrogen / water / 100 °C / 37503.8 Torr / Sealed tube 3: thionyl chloride / 4 h / 80 °C / Alkaline conditions View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1200-22-2

(R)-1,2-dithiolane-3-pentanoic acid

Conditions

Conditions	Yield
With ammonium hydrogen sulfite; sodium sulfide nonahydrate; sulfur In propan-1-ol; water; isopropyl alcohol at 70℃; for 3.5h; Temperature; Solvent; Reagent/catalyst; Inert atmosphere; Darkness;	30.6%

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

98997-92-3

6,8-dichloro-octan-1-ol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride; diethyl ether

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

100911-03-3

5,7-dichloro-heptanoic acid

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

120089-31-8

8-bromo-1,3-dichloro-octane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: lithium alanate; diethyl ether 2: tetrachloromethane; phosphorus (III)-bromide View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

99062-11-0

7,9-dichloro-nonanenitrile

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: lithium alanate; diethyl ether 2: tetrachloromethane; phosphorus (III)-bromide 3: aqueous ethanol View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

5,7-dichloro-heptanoic acid ethyl ester

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 2: benzene; sulfuric acid View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

100402-37-7

7,9-dichloro-nonanoic acid ethyl ester

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: lithium alanate; diethyl ether 2: tetrachloromethane; phosphorus (III)-bromide 3: aqueous ethanol 4: ethanol; hydrogen chloride 5: water View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

110358-77-5

7,9-dichloro-nonaneimidic acid ethyl ester; hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: lithium alanate; diethyl ether 2: tetrachloromethane; phosphorus (III)-bromide 3: aqueous ethanol 4: ethanol; hydrogen chloride View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

41443-60-1

(+)-6,8-dichloro-octanoic acid

Conditions

Conditions	Yield
Alkaline aqueous solution;

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

46353-61-1

1,2-dithiolan-3-yl pentanoic acid ethyl ester

Conditions

Conditions	Yield
With sodium sulfide; tetrabutylammomium bromide; sulfur In toluene for 5h; Reflux;
With sodium sulfide; tetrabutylammomium bromide; sulfur In water at 85℃; for 3h; Temperature; Reagent/catalyst;
With sodium sulfide; sulfur In water at 50 - 84℃; for 3h;

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1451075-56-1

sodium 6,8-dichlorooctanoate

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 50℃; for 1.5h;
With water; sodium hydroxide In ethanol at 50℃; for 1.5h; Green chemistry;
With sodium hydroxide In water at 65℃; for 3h;
With water; sodium hydroxide In ethanol at 50℃; for 2h; Temperature; Solvent;

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-63-9

N'-(4-chlorobenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate 5.1: ethanol / 20 °C View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-64-0

N'-(furan-2-ylmethylene)-5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate 5.1: ethanol / 20 °C View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-65-1

N'-(2-chlorobenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate 5.1: ethanol / 20 °C View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-66-2

N'-(2-hydroxybenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate 5.1: ethanol / Reflux View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-67-3

N'-(4-methylbenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate 5.1: ethanol / Reflux View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-68-4

N'-(3-methoxy-4-hydroxybenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate 5.1: ethanol / Reflux View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-69-5

N'-(3-hydroxy-4-methoxybenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate 5.1: ethanol / Reflux View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-70-8

N'-(4-(dimethylamino)benzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate 5.1: ethanol / Reflux View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-71-9

N'-(4-methoxybenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate 5.1: ethanol / Reflux View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-72-0

N'-(4-hydroxybenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate 5.1: ethanol / Reflux View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1451075-57-2

C8H13O2Se2(1-)*Na(1+)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2: disodium diselenide / ethanol; water / 2 h / 65 °C View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-73-1

N'-(3,4-dihydroxybenzylidene)-5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate 5.1: ethanol / Reflux View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

6708-13-0

5-(1,2-diselenolan-3-yl)pentanoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-57-1

ethyl 5-(1,2-diselenolan-3-yl)pentanoate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C View Scheme

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

1456816-58-2

5-(1,2-diselenolan-3-yl)pentanehydrazide

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: sodium hydroxide / ethanol; water / 1.5 h / 50 °C 2.1: disodium diselenide / ethanol; water / 2 h / 65 °C 2.2: 0 °C / pH 1 3.1: acetyl chloride / 2 h / 20 °C 3.2: 20 °C 4.1: hydrazine hydrate View Scheme

Ethyl 6,8-dichlorooctanoate Chemical Properties

Ethyl 6,8-dichlorooctanoate Uses

Ethyl 6,8-dichlorooctanoate Toxicity Data With Reference

Ethyl 6,8-dichlorooctanoate Safety Profile