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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Benzp-Dinitride-Thio-Ketone supplier in China in stock

Cas:4547-02-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

BENZP-DINITRIDE-THIO-KETONE Basic information Product Name: BENZP-DINITRIDE-THIO-KETONE Synonyms: BENZP-DINITRIDE-THIO-KETONE;7-Chloro-5-phenyl-1H-benzo[e][1,4]diaz

BENZP-DINITRIDE-THIO-KETONE

Cas:4547-02-8

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione CAS 4547-02-8

Cas:4547-02-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 4547-02-8 with competitive price

Cas:4547-02-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione 4547-02-8

Cas:4547-02-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

BENZP-DINITRIDE-THIO-KETONE CAS:4547-02-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organi

BENZP-DINITRIDE-THIO-KETONE CAS:4547-02-8

Cas:4547-02-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Advantage cof, mof ligand manufacturer Product Detail bes

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione

Cas:4547-02-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: BENZP-DINITRIDE-THIO-KETONE Synonyms: BENZP-DINITRIDE-THIO-KETONE;7-Chloro-5-phenyl-1H-benzo[e][1,4]diazepine-2(3H)-thione;Thionordiazepam;7-Chloro-5-phenyl-1H-benzo[e][1,4]diazepine-2(3H);Benzodiazepines Intermediate 1 CAS: 4547

BENZP-DINITRIDE-THIO-KETONE big supplier with lower price

Cas:4547-02-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

BENZP-DINITRIDE-THIO-KETONE

Cas:4547-02-8

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione

Cas:4547-02-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanxi Ankesi Biotechnology Co., Ltd

Our Advantage 1. Rich experience We specialize in this filed for many years, our APIs exported to all over the world and and we established long friendly relations of cooperation with our clients. 2. Great quality,purity and favorable Good qual

BENZP-DINITRIDE-THIO-KETONE CAS 4547-02-8 with competitive price AKS

Cas:4547-02-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Triumph International Development Limilted

Appearance:white or yellowish white flaky crystal Storage:Keep the sun from direct sunlight ;prevention against high temperature Package:As customer request Application:Used for research and industrial manufacture. Transportatio

7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepine-2-thione

Cas:4547-02-8

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione; Benzp-dinitride-thio-ketone

Cas:4547-02-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione; Benzp-dinitride-thio-ketone

Cas:4547-02-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione

Cas:4547-02-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Benzp-Dinitride-Thio-Ketone

Cas:4547-02-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

7-Chloro-5-phenyl-1H-benzo[e]-[1,4]diazepine-2(3H)-thioneAppearance:white powder Storage:Store in dry, dark and ventilated place Package:according to customers' requirements Application:chemical research Transportation:By air(EMS or EUB or FedEx or T

7-Chloro-5-phenyl-1H-benzo[e]-[1,4]diazepine-2(3H)-thione

Cas:4547-02-8

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Benzp-Dinitride-Thio-Ketone supplier in China in stock

Cas:4547-02-8

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:light yellow crystal solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:Hypn

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione

Cas:4547-02-8

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

tianfu-chem_4547-02-8// 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione

Cas:4547-02-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 7-Chloro-1,3-dihydro-5-Phenyl-2H-1,4-Benzodiazepine-2-Thione CAS No.:4547-02-8 Molecule Formula:C15H11ClN2S Molecule Weight:286.78 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standar

Best Quality 7-Chloro-1,3-dihydro-5-Phenyl-2H-1,4-Benzodiazepine-2-Thione

Cas:4547-02-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Benzp-Dinitride-Thio-Ketone

Cas:4547-02-8

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Top Purity SupplierBENZP-DINITRIDE-THIO-KETONE

Cas:4547-02-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Benzp-Dinitride-Thio-Ketone supplier in China in stock

Cas:4547-02-8

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

BENZP-DINITRIDE-THIO-KETONE

Cas:4547-02-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione; Benzp-dinitride-thio-ketone

Cas:4547-02-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Synthetic route

desmethyldiazepam
1088-11-5

desmethyldiazepam

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

Conditions
ConditionsYield
With n-butyllithium; tetraphosphorus decasulfide In tetrahydrofuran; hexane for 16h; Heating;87%
With tetraphosphorus decasulfide In pyridine Heating; 1.) 30 min. reflux, 2.) 1 h;67%
With tetraphosphorus decasulfide; sodium hydrogencarbonate In acetonitrile for 24h; Heating;
With Lawessons reagent In 1,2-dimethoxyethane at 75℃;
With tetraphosphorus decasulfide; triethylamine In toluene at 75℃; for 8h; Solvent; Temperature; Inert atmosphere;175 g
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one
2898-08-0

2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

Conditions
ConditionsYield
Stage #1: 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one With aluminum (III) chloride; chlorine In dichloromethane at 10 - 20℃;
Stage #2: With sodiumsulfide nonahydrate; tetrabutylammomium bromide; dihydrogen peroxide for 2h; Reflux;
78.7%
di-morpholin-4-yl-phosphinic acid 7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl ester
59318-11-5

di-morpholin-4-yl-phosphinic acid 7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl ester

triethylimine

triethylimine

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

Conditions
ConditionsYield
In tetrahydrofuran
2-Amino-5-chlorobenzophenone
719-59-5

2-Amino-5-chlorobenzophenone

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: cyclohexane / 4 h / 60 - 81 °C
2: hexamethylenetetramine; ammonium bicarbonate / ethanol / 6 h / 40 - 50 °C
3: triethylamine; tetraphosphorus decasulfide / toluene / 8 h / 75 °C / Inert atmosphere
View Scheme
(2-Aminomethyl-[1,3]dioxolan-2-yl)-methanol
45649-48-7

(2-Aminomethyl-[1,3]dioxolan-2-yl)-methanol

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

{2-[(7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-methyl]-[1,3]dioxolan-2-yl}-methanol
59820-66-5

{2-[(7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-methyl]-[1,3]dioxolan-2-yl}-methanol

Conditions
ConditionsYield
In ethanol at 100℃; for 3h;90%
N-Methylhydroxylamine
593-77-1

N-Methylhydroxylamine

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

N-(7-Chlor-5-phenyl-3H-1,4-benzodiazepin-2-yl)-N-methylhydroxylamin
77175-99-6

N-(7-Chlor-5-phenyl-3H-1,4-benzodiazepin-2-yl)-N-methylhydroxylamin

Conditions
ConditionsYield
In methanol for 1.5h; Heating;87%
(3-azidoacetonyl)amine, ethylene ketal
57963-29-8

(3-azidoacetonyl)amine, ethylene ketal

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

(2-azidomethyl-[1,3]dioxolan-2-ylmethyl)-(7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)-amine
57963-28-7

(2-azidomethyl-[1,3]dioxolan-2-ylmethyl)-(7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)-amine

Conditions
ConditionsYield
In ethanol87%
In ethanol; water
2-(methanesulfonamido)propionhydrazide
117267-37-5

2-(methanesulfonamido)propionhydrazide

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

N-[1-(8-Chloro-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulen-1-yl)-ethyl]-methanesulfonamide
124938-99-4

N-[1-(8-Chloro-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulen-1-yl)-ethyl]-methanesulfonamide

Conditions
ConditionsYield
Heating;84%
7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

ethylhydrazine carboxylate
4114-31-2

ethylhydrazine carboxylate

3-(7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-yl)carbazic acid ethyl ester
31262-81-4

3-(7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-yl)carbazic acid ethyl ester

Conditions
ConditionsYield
In ethanol for 24h; Heating;77%
glycine
56-40-6

glycine

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

N-(7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)-glycine
61197-97-5

N-(7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)-glycine

Conditions
ConditionsYield
With sodium carbonate In ethanol; water77%
7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

4-methyl-1-piperazinylacetic acid hydrazide
24632-44-8

4-methyl-1-piperazinylacetic acid hydrazide

8-chloro-1-(4-methyl-piperazin-1-ylmethyl)-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine
40070-25-5

8-chloro-1-(4-methyl-piperazin-1-ylmethyl)-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine

Conditions
ConditionsYield
In butan-1-ol for 4h; Heating;72%
ethyl(methylthio)acetic hydrazide
74085-88-4

ethyl(methylthio)acetic hydrazide

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

8-Chloro-1-methylsulfanylmethyl-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulene
85677-78-7

8-Chloro-1-methylsulfanylmethyl-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulene

Conditions
ConditionsYield
In butan-1-ol Heating;65%
2-[2-(2-Aminomethyl-[1,3]dioxolan-2-yl)-ethyl]-isoindole-1,3-dione
63200-67-9

2-[2-(2-Aminomethyl-[1,3]dioxolan-2-yl)-ethyl]-isoindole-1,3-dione

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

A

2-{2-[2-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-ethyl]-[1,3]dioxolan-2-ylmethyl}-isoindole-1,3-dione
76879-47-5

2-{2-[2-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-ethyl]-[1,3]dioxolan-2-ylmethyl}-isoindole-1,3-dione

B

N-(2-{2-[(7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-methyl]-[1,3]dioxolan-2-yl}-ethyl)-phthalimide
63200-73-7

N-(2-{2-[(7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-methyl]-[1,3]dioxolan-2-yl}-ethyl)-phthalimide

Conditions
ConditionsYield
In ethanol at 60℃;A 36%
B 65%
In ethanol at 60℃; overnight;A 36%
B 58%
2-(ethanesulfonamido)propionhydrazide
117267-38-6

2-(ethanesulfonamido)propionhydrazide

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

Ethanesulfonic acid [1-(8-chloro-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulen-1-yl)-ethyl]-amide
124939-02-2

Ethanesulfonic acid [1-(8-chloro-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulen-1-yl)-ethyl]-amide

Conditions
ConditionsYield
Heating;63%
(ethanesulfonamido)acethydrazide
117267-36-4

(ethanesulfonamido)acethydrazide

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

Ethanesulfonic acid (8-chloro-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulen-1-ylmethyl)-amide
117267-42-2

Ethanesulfonic acid (8-chloro-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulen-1-ylmethyl)-amide

Conditions
ConditionsYield
Heating;61%
4-hydroxy-but-2-ynamine
63200-68-0

4-hydroxy-but-2-ynamine

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

4-(7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-but-2-yn-1-ol
63200-69-1

4-(7-chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-but-2-yn-1-ol

Conditions
ConditionsYield
In tetrahydrofuran Ambient temperature;57%
(methanesulfonamido)acethydrazide
117267-35-3

(methanesulfonamido)acethydrazide

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

N-(8-Chloro-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulen-1-ylmethyl)-methanesulfonamide
117267-39-7

N-(8-Chloro-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulen-1-ylmethyl)-methanesulfonamide

Conditions
ConditionsYield
Heating;57%
N-<<2-(aminomethyl)-1,3-dioxolan-2-yl>methyl>phthalimide
57963-14-1

N-<<2-(aminomethyl)-1,3-dioxolan-2-yl>methyl>phthalimide

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

A

C21H16N2O6
76879-39-5

C21H16N2O6

B

N-<<2-<<7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-yl>amino>methyl>-1,3-dioxolan-2-yl>methylphthalimide
57963-16-3

N-<<2-<<7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-yl>amino>methyl>-1,3-dioxolan-2-yl>methylphthalimide

Conditions
ConditionsYield
In ethanol at 60℃; for 18h;A 1.9 g
B 52.8%
N-benzyl hydroxylalmine
622-30-0

N-benzyl hydroxylalmine

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

N-Benzyl-N-(7-chlor-5-phenyl-3H-1,4-benzodiazepin-2-yl)-hydroxylamin
77176-00-2

N-Benzyl-N-(7-chlor-5-phenyl-3H-1,4-benzodiazepin-2-yl)-hydroxylamin

Conditions
ConditionsYield
In methanol for 1.5h; Heating;48%
aqueous potassium hydroxide

aqueous potassium hydroxide

1-chloro-2-(4-methyl-1-piperazinyl)ethane dihydrochloride
5753-26-4, 92333-85-2, 126055-32-1

1-chloro-2-(4-methyl-1-piperazinyl)ethane dihydrochloride

(2E)-but-2-enedioic acid
110-17-8

(2E)-but-2-enedioic acid

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

2-[2-(4-methyl-1-piperazinyl)ethylthio]-5-phenyl-7-chloro-3H-1,4-benzodiazepine difumarate

2-[2-(4-methyl-1-piperazinyl)ethylthio]-5-phenyl-7-chloro-3H-1,4-benzodiazepine difumarate

Conditions
ConditionsYield
In tetrahydrofuran; ethanol42%
5-methyl-1H-imidazole-4-carboxylic acid hydrazide
71704-67-1

5-methyl-1H-imidazole-4-carboxylic acid hydrazide

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

8-chloro-1-(5-methyl-4-imidazolyl)-6-phenyl-4H-s-triazolo<4,3-a>-1,4-benzodiazepine
117267-50-2

8-chloro-1-(5-methyl-4-imidazolyl)-6-phenyl-4H-s-triazolo<4,3-a>-1,4-benzodiazepine

Conditions
ConditionsYield
In butan-1-ol for 8h; Heating;38%
3-ethyl-2-methylsulfanyl-benzothiazolium; toluene-4-sulfonate
50716-34-2

3-ethyl-2-methylsulfanyl-benzothiazolium; toluene-4-sulfonate

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

7-chloro-3-(3-ethyl-3H-benzothiazol-2-ylidene)-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepine-2-thione
35579-60-3

7-chloro-3-(3-ethyl-3H-benzothiazol-2-ylidene)-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepine-2-thione

Conditions
ConditionsYield
With triethylamine In ethanol
(2-chloroethyl)dimethylamine hydrochloride
4584-46-7

(2-chloroethyl)dimethylamine hydrochloride

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

2-(2-dimethylaminoethylthio)-5-phenyl-7-chloro-3H-1,4-benzodiazepine
67974-46-3

2-(2-dimethylaminoethylthio)-5-phenyl-7-chloro-3H-1,4-benzodiazepine

Conditions
ConditionsYield
With potassium hydroxide In tetrahydrofuran; water for 1.5h; Ambient temperature; Yield given;
C-(2-Dimethylaminomethyl-[1,3]dioxolan-2-yl)-methylamine
76879-44-2

C-(2-Dimethylaminomethyl-[1,3]dioxolan-2-yl)-methylamine

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

7-chloro-5-phenyl-2-[[3-(dimethylamino)acetonyl]amino]-3H-1,4-benzodiazepine, ethylene ketal
57963-30-1

7-chloro-5-phenyl-2-[[3-(dimethylamino)acetonyl]amino]-3H-1,4-benzodiazepine, ethylene ketal

Conditions
ConditionsYield
In butan-1-ol at 60℃; for 0.5h;
2-[2-(2-Aminomethyl-[1,3]dioxolan-2-yl)-ethyl]-isoindole-1,3-dione
63200-67-9

2-[2-(2-Aminomethyl-[1,3]dioxolan-2-yl)-ethyl]-isoindole-1,3-dione

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

A

2-[4-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-2-oxo-butyl]-isoindole-1,3-dione
76879-48-6

2-[4-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-2-oxo-butyl]-isoindole-1,3-dione

B

2-[4-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-3-oxo-butyl]-isoindole-1,3-dione
76900-22-6

2-[4-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-ylamino)-3-oxo-butyl]-isoindole-1,3-dione

C

N-[2-(8-chloro-6-phenyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-1-yl)-ethyl]-phthalimide
63232-06-4

N-[2-(8-chloro-6-phenyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-1-yl)-ethyl]-phthalimide

Conditions
ConditionsYield
With sulfuric acid 1.) EtOH, 60 deg C, 2.) RT; Yield given. Multistep reaction. Yields of byproduct given;
With sulfuric acid 1.) EtOH, 60 deg C 2.) RT; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
methylamine
74-89-5

methylamine

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

(7-chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-ylidene)-methyl-amine
4393-72-0

(7-chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-ylidene)-methyl-amine

Conditions
ConditionsYield
In water; acetonitrile at 20℃; for 3h;
7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione
4547-02-8

7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

7-chloro-2-(N-nitrosomethylamino)-5-phenyl-3H-1,4-benzodiazepine
819793-73-2

7-chloro-2-(N-nitrosomethylamino)-5-phenyl-3H-1,4-benzodiazepine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetonitrile; H2O / 3 h / 20 °C
2: 0.55 g / sodium nitrite; AcOH / 3 h / 20 °C
View Scheme

Raw Materials

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