Ethyl methyl carbonate supplier

Name
Ethyl methyl carbonate
EINECS 208-760-7
CAS No. 623-53-0
Article Data67
CAS DataBase
Density 0.997 g/cm³
Solubility insoluble in water
Hazard Symbols Xi
Synonyms Methyl ethyl carbonate;
PSA 35.53000
LogP 0.78930

Synthetic route

: 64-17-5
ethanol

: 79-22-1
methyl chloroformate

: 623-53-0
ethyl methyl carbonate

Conditions

Conditions	Yield
With 1,2-dimethyl-1H-imidazole at 0 - 20℃; for 1h; Product distribution / selectivity;	98.1%
With 1-methyl-1H-imidazole at 0 - 20℃; for 1h;	97.4%
With 1-methyl-1H-imidazole In bis-2-propyl carbonate at 0 - 20℃; for 1h;	97.6%

: 64-17-5
ethanol

: 616-38-6
carbonic acid dimethyl ester

: 623-53-0
ethyl methyl carbonate

Conditions

Conditions	Yield
With dicobalt octacarbonyl at 180℃; for 1h; chemoselective reaction;	98%
With Novozyme 435 at 60℃; for 24h; Green chemistry; Enzymatic reaction;	90.3%
With lanthanum(III) chloride; calcium chloride; sodium hydroxide at 90℃; for 12h; Reagent/catalyst; Molecular sieve; Glovebox;	51.47%

: 132819-56-8
3-Methyl-4-phenyl-4H-pyridine-1-carboxylic acid ethyl ester

A: 2052-92-8
3-methyl-4-phenyl-pyridine

B: 623-53-0
ethyl methyl carbonate

Conditions

Conditions	Yield
With sodium methylate In methanol at 18℃; anodic oxidation (graphite-rod electrodes), 6 F/mol passed through the solution;	A 90% B n/a

: 616-38-6
carbonic acid dimethyl ester

: 105-58-8
Diethyl carbonate

: 623-53-0
ethyl methyl carbonate

Conditions

Conditions	Yield
With Zeolitic imidazole framework (ZIF)-67 at 100℃; for 24h; Reagent/catalyst; Concentration;	83.39%
With Mg/Fe oxide calcined at 400°C at 100℃; for 1.5h; Catalytic behavior; Reagent/catalyst; Temperature;	66%
With Zn(2-methylimidazolate)2 at 100℃; for 3h; Reagent/catalyst; Temperature; Time;	65.7%

: 64-17-5
ethanol

: 616-38-6
carbonic acid dimethyl ester

A: 623-53-0
ethyl methyl carbonate

B: 105-58-8
Diethyl carbonate

Conditions

Conditions	Yield
With sodium methylate In methanol at 69 - 120℃; for 6h; Reflux;	A n/a B 73%
With silica-alumina at 78℃; under 760.051 Torr; for 2h; pH=11; Reagent/catalyst; Temperature;	A 63.9% B n/a
With 15percentMgO-5percentMgCl-2percentLa2CO3 supported on Al2O3-SiO2 at 200℃; under 760.051 Torr; Reagent/catalyst; Temperature;	A 57.37% B n/a

...Expand

: 64-17-5
ethanol

: 584-07-6
methyl N-hydroxycarbamate

A: 623-53-0
ethyl methyl carbonate

B: 616-38-6
carbonic acid dimethyl ester

Conditions

Conditions	Yield
With lead dioxide In dichloromethane at 40℃; for 0.166667h;	A 14.3% B 70%
With lead dioxide at 40℃; for 0.166667h; Product distribution; reaction at -10 deg C; other alcohols, water; oxidation of alkyl N-hydroxycarbamates in the presence of alcohols; competitive alcoholysis; effect of the nature of alkyl group, alcohol reactivity, temperature on the product ratio;	A 14.3% B 70%

...Expand

: 67-56-1
methanol

: 589-41-3
ethyl N-hydroxylcarbamate

A: 623-53-0
ethyl methyl carbonate

B: 105-58-8
Diethyl carbonate

Conditions

Conditions	Yield
With lead dioxide In dichloromethane at 40℃; for 0.166667h;	A 25.1% B 66.3%

...Expand

: 82126-20-3
1-ethoxycarbonyl-4-phenyl-1,4-dihydropyridine

A: 939-23-1
p-phenylpyridine

B: 623-53-0
ethyl methyl carbonate

Conditions

Conditions	Yield
With sodium methylate In methanol at 18℃; anodic oxidation (graphite-rod electrodes), 6 F/mol passed through the solution;	A 65% B n/a

: 132819-55-7
2-Methyl-4-phenyl-4H-pyridine-1-carboxylic acid ethyl ester

A: 15032-21-0
2-methyl-4-phenylpyridine

B: 623-53-0
ethyl methyl carbonate

Conditions

Conditions	Yield
With sodium methylate In methanol at 18℃; anodic oxidation (graphite-rod electrodes);	A 60% B n/a

: 631-22-1
diethyl dibromomalonate

: 110-83-8
cyclohexene

A: 623-53-0
ethyl methyl carbonate

B: 2415-79-4
7,7-dibromonorcarane

Conditions

Conditions	Yield
With sodium methylate at 0℃;	A n/a B 60%
With sodium methylate at 0℃; Mechanism; reactions under var. conditions;	A n/a B 60%

...Expand

: 64-17-5
ethanol

: 124-38-9
carbon dioxide

: 74-88-4
methyl iodide

: 623-53-0
ethyl methyl carbonate

Conditions

Conditions	Yield
Stage #1: carbon dioxide With 1-butyl-3-methyl-1H-imidazol-3-iumhydrogencarbonate at 25℃; under 760.051 Torr; for 6h; Stage #2: ethanol; methyl iodide at 25℃; under 760.051 Torr; for 12h;	57.6%

...Expand

: 141-78-6
ethyl acetate

: 616-38-6
carbonic acid dimethyl ester

A: 79-20-9
acetic acid methyl ester

B: 623-53-0
ethyl methyl carbonate

C: 105-58-8
Diethyl carbonate

Conditions

Conditions	Yield
lithium methanolate at 77℃; for 3h; Product distribution / selectivity;	A n/a B 50% C n/a
lithium amide at 78℃; for 4h; Product distribution / selectivity;	A n/a B 50% C n/a
lithium methanolate at 78℃; for 3h; Product distribution / selectivity;	A n/a B 50% C n/a
lithium amide at 77℃; for 4h; Product distribution / selectivity;	A n/a B 47% C n/a

...Expand

: 79-20-9
acetic acid methyl ester

: 105-58-8
Diethyl carbonate

A: 623-53-0
ethyl methyl carbonate

B: 616-38-6
carbonic acid dimethyl ester

Conditions

Conditions	Yield
lithium methanolate at 78℃; for 3h; Product distribution / selectivity;	A 50% B n/a

...Expand

: 67-56-1
methanol

: 745829-72-5
ethyl N-acetoxy-N-methoxycarbamate

A: 623-53-0
ethyl methyl carbonate

B: 3871-28-1
N-Ethoxycarbonyl-O-methylhydroxylamine

C: ethyl N,N-dimethoxycarbamate

Conditions

Conditions	Yield
at 20℃; for 98h;	A 44.4% B 7.3% C 33.9%

...Expand

: 67-56-1
methanol

: ethyl N-acetoxy-N-isopropoxycarbamate

A: 623-53-0
ethyl methyl carbonate

B: ethyl N-isopropoxy-N-isopropoxycarbamate

Conditions

Conditions	Yield
at 20℃; for 120h;	A 38.7% B 44%

...Expand

: 64-17-5
ethanol

: 616-38-6
carbonic acid dimethyl ester

A: 67-56-1
methanol

B: 623-53-0
ethyl methyl carbonate

C: 105-58-8
Diethyl carbonate

Conditions

Conditions	Yield
lithium methanolate at 78℃; for 4h; Product distribution / selectivity;	A n/a B 44% C n/a

...Expand

: 63755-37-3
4-methyl-2-phenyl-2H-pyridine-1-carboxylic acid ethyl ester

A: 623-53-0
ethyl methyl carbonate

B: 3475-21-6
4-methyl-2-phenylpyridine

Conditions

Conditions	Yield
With sodium methylate In methanol at 18℃; anodic oxidation (graphite-rod electrodes);	A n/a B 38%

: 149-73-5
trimethyl orthoformate

: 745829-70-3
ethyl N-chloro-N-methoxycarbamate

A: 623-53-0
ethyl methyl carbonate

B: 3871-28-1
N-Ethoxycarbonyl-O-methylhydroxylamine

Conditions

Conditions	Yield
In methanol at -8 - 5℃; for 21h;	A 22% B 35%

...Expand

: 132819-57-9
2-Butyl-4-methyl-2H-pyridine-1-carboxylic acid ethyl ester

A: 6304-31-0
2-n-butyl-4-methylpyridine

B: 623-53-0
ethyl methyl carbonate

Conditions

Conditions	Yield
With sodium methylate In methanol at 18℃; anodic oxidation (graphite-rod electrodes);	A 31% B n/a

: 67-56-1
methanol

: 745829-70-3
ethyl N-chloro-N-methoxycarbamate

A: 623-53-0
ethyl methyl carbonate

B: 3871-28-1
N-Ethoxycarbonyl-O-methylhydroxylamine

C: 90222-29-0
N,N'-bis(ethoxycarbonyl)-N,N'-dimethoxyhydrazine

Conditions

Conditions	Yield
With sodium acetate at 30 - 31℃; for 96h;	A 30% B 11% C 14%

...Expand

: 67-56-1
methanol

: 64-17-5
ethanol

: 124-38-9
carbon dioxide

A: 623-53-0
ethyl methyl carbonate

B: 616-38-6
carbonic acid dimethyl ester

C: 105-58-8
Diethyl carbonate

Conditions

Conditions	Yield
titanium tetramethoxide at -168 - 150℃; for 15h; Cooling with ethanol-dry ice;	A 23% B 2% C 3%

...Expand

: 67-56-1
methanol

: 87463-09-0
(ethoxydichloromethyl)sulfenyl chloride

A: 74-87-3
methylene chloride

B: 623-53-0
ethyl methyl carbonate

...Expand

: 67-56-1
methanol

: 541-41-3
chloroformic acid ethyl ester

: 623-53-0
ethyl methyl carbonate

: 124-41-4
sodium methylate

: 541-41-3
chloroformic acid ethyl ester

: 623-53-0
ethyl methyl carbonate

: 141-52-6
sodium ethanolate

: 79-22-1
methyl chloroformate

: 623-53-0
ethyl methyl carbonate

: 67-56-1
methanol

: 100314-09-8
trans-N.N'-Dinitroso-N.N'-dicarbethoxy-1.4-diamino-cyclohexan

: 623-53-0
ethyl methyl carbonate

Conditions

Conditions	Yield
With sodium methylate In cyclohexanone

: 64-17-5
ethanol

: 107820-42-8
1-Methoxycarbonyl-3,5-dimethyl-pyridinium; chloride

A: 623-53-0
ethyl methyl carbonate

B: 36316-70-8
3,5-dimethyl-pyridinium-chloride

Conditions

Conditions	Yield
at 25℃; Thermodynamic data; ΔH(excit.), ΔS(excit.);

...Expand

: 64-17-5
ethanol

: 3-Cyano-1-methoxycarbonyl-pyridinium; chloride

A: 623-53-0
ethyl methyl carbonate

B: 65520-09-4
3-cyanopyridine hydrochloride

Conditions

Conditions	Yield
at 25℃; Mechanism; Thermodynamic data; other 1-methoxycarbonylpyridinium chlorides; ΔH(excit.), ΔS(excit.);

...Expand

: 1609-47-8
diethyl dicarbonate

: 4525-33-1
dimethyl dicarbonate

A: 623-53-0
ethyl methyl carbonate

B: 124-38-9
carbon dioxide

Conditions

Conditions	Yield
In dichloromethane Ambient temperature;

...Expand

: 160663-37-6
2,2-Dichloro-3,3-diethoxy-propionic acid ethyl ester

: 124-41-4
sodium methylate

A: 619-33-0
dichloroacetaldehyde diethyl acetal

B: 623-53-0
ethyl methyl carbonate

Conditions

Conditions	Yield
In diethyl ether at 20℃; for 4h;

...Expand

: 623-53-0
ethyl methyl carbonate

: 7637-07-2
boron trifluoride

: 220991-85-5
BF3-EMC

Conditions

Conditions	Yield
for 48h; Schlenk technique; Inert atmosphere; Glovebox;	97%

: 75-89-8
2,2,2-trifluoroethanol

: 623-53-0
ethyl methyl carbonate

: methyl (2,2,2-trifluoroethyl) carbonate

Conditions

Conditions	Yield
With tributylmethylammonium bis(trifluoromethanesulfonyl)imide salt In triethylamine at 50 - 80℃; for 15h; Temperature; Autoclave; Large scale;	91%

: 623-53-0
ethyl methyl carbonate

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 2881-83-6
ethyl 4-methoxybenzoylacetate

Conditions

Conditions	Yield
Stage #1: ethyl methyl carbonate With sodium hydride at 20℃; Inert atmosphere; Stage #2: 1-(4-methoxyphenyl)ethanone for 4h; Inert atmosphere; Reflux;	86%

: 623-53-0
ethyl methyl carbonate

: 122-00-9
para-methylacetophenone

: 27835-00-3
ethyl (4-methylbenzoyl)acetate

Conditions

Conditions	Yield
Stage #1: ethyl methyl carbonate With sodium hydride at 20℃; Inert atmosphere; Stage #2: para-methylacetophenone for 4h; Inert atmosphere; Reflux;	83%

: 623-53-0
ethyl methyl carbonate

: 99-90-1
para-bromoacetophenone

: 26510-95-2
ethyl 4-Bromobenzoylacetate

Conditions

Conditions	Yield
Stage #1: ethyl methyl carbonate With sodium hydride at 20℃; Inert atmosphere; Stage #2: para-bromoacetophenone for 4h; Inert atmosphere; Reflux;	80%

Ethyl methyl carbonate Chemical Properties

Molecule structure of Ethyl methyl carbonate (CAS NO.623-53-0):

IUPAC Name: Ethyl methyl carbonate
Molecular Weight: 104.10452 g/mol
Molecular Formula: C₄H₈O₃
Density: 0.997 g/cm³
Melting Point: -14.5 °C
Boiling Point: 107.5 °C at 760 mmHg
Flash Point: 26.7 °C
Index of Refraction: 1.378
Molar Refractivity: 24.1 cm³
Molar Volume: 104.4 cm³
Surface Tension: 25.9 dyne/cm
Enthalpy of Vaporization: 34.63 kJ/mol
Vapour Pressure: 27 mmHg at 25 °C
XLogP3-AA: 0.9
H-Bond Acceptor: 3
Rotatable Bond Count: 3
Exact Mass: 104.047344
MonoIsotopic Mass: 104.047344
Topological Polar Surface Area: 35.5
Heavy Atom Count: 7
Canonical SMILES: CCOC(=O)OC
InChI: InChI=1S/C4H8O3/c1-3-7-4(5)6-2/h3H2,1-2H3
InChIKey: JBTWLSYIZRCDFO-UHFFFAOYSA-N
Product Categories: CARBONATES

Ethyl methyl carbonate Uses

Ethyl methyl carbonate (CAS NO.623-53-0) is used in organic synthesis.

Ethyl methyl carbonate Safety Profile

Risk Statements: 10
R10:Flammable.
Safety Statements: 16
S16:Keep away from sources of ignition.
RIDADR: 3272

Ethyl methyl carbonate Specification

Ethyl methyl carbonate (CAS NO.623-53-0) is also named as carbonic acid, ethyl methyl ester ; Ethyl-methylcarbonat ; Carbonic acid, ethyl-, methyl ester ; Ethoxyacetic acid, methyl ester . Ethyl methyl carbonate (CAS NO.623-53-0) is colorless liquid. It is insoluble in water, soluble in ether, alcohol.

Product Name

Ethyl methyl carbonate

Synthetic route

Ethyl methyl carbonate Chemical Properties

Ethyl methyl carbonate Uses

Ethyl methyl carbonate Safety Profile

Ethyl methyl carbonate Specification

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