Product Name

  • Name

    Histamine dihydrochloride

  • EINECS 200-298-4
  • CAS No. 56-92-8
  • Article Data12
  • CAS DataBase
  • Density 1.14 g/cm3
  • Solubility 0.1 g/mL in water
  • Melting Point 249-252 °C(lit.)
  • Formula C5H11Cl2N3
  • Boiling Point 331 °C at 760 mmHg
  • Molecular Weight 184.068
  • Flash Point 180.3 °C
  • Transport Information UN 3335
  • Appearance white powder
  • Safety 22-26-36/37/39-45-37-36/37
  • Risk Codes 36/37/38-42/43-42-22
  • Molecular Structure Molecular Structure of 56-92-8 (Histamine dihydrochloride)
  • Hazard Symbols HarmfulXn, IrritantXi
  • Synonyms 1H-Imidazole-4-ethanamine,dihydrochloride (9CI);Histamine, dihydrochloride (8CI);2-(1H-Imidazol-4-yl)ethanamine dihydrochloride;4-(2-Aminoethyl)imidazole dihydrochloride;Ceplene;Histaminechloride;Histamine dichloride;1H-Imidazole-5-ethanamine,hydrochloride (1:2);
  • PSA 54.70000
  • LogP 2.21520

Synthetic route

1H-imidazole-4-carboxaldehyde oxime
57090-90-1

1H-imidazole-4-carboxaldehyde oxime

histamine dichloride
56-92-8

histamine dichloride

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen; acetyl chloride In methanol at 0℃; for 17.5h; Inert atmosphere;98%
L-histidine
71-00-1

L-histidine

histamine dichloride
56-92-8

histamine dichloride

Conditions
ConditionsYield
Stage #1: L-histidine With (R)-Carvone In propan-1-ol at 190℃; under 11251.1 Torr; for 0.2h; Sealed tube;
Stage #2: With hydrogenchloride In propan-1-ol; water at 190℃; for 0.0833333h;
92%
Multi-step reaction with 2 steps
1: propan-1-ol / 20 - 190 °C / Green chemistry
2: hydrogenchloride / propan-1-ol / 0.2 h / 190 °C / Green chemistry
View Scheme
Multi-step reaction with 3 steps
1: copper(I) bromide / 10 h / 100 - 110 °C / Inert atmosphere; Darkness
2: hydrogenchloride / 30 °C
3: hydrogenchloride / methanol / 30 °C
View Scheme
C15H21N3

C15H21N3

histamine dichloride
56-92-8

histamine dichloride

Conditions
ConditionsYield
With hydrogenchloride In propan-1-ol at 190℃; for 0.2h; Temperature; Green chemistry;92%
Nα-Trityl-L-histidin
58995-29-2

Nα-Trityl-L-histidin

histamine dichloride
56-92-8

histamine dichloride

Conditions
ConditionsYield
Stage #1: Nα-Trityl-L-histidin With (R)-Carvone In propan-1-ol at 0 - 190℃; Green chemistry;
Stage #2: With hydrogenchloride In propan-1-ol; water at 190℃; for 0.0833333h; Microwave irradiation; Green chemistry;
86%
4-(2-Azido-ethyl)-1-(toluene-4-sulfonyl)-1H-imidazole
74294-62-5

4-(2-Azido-ethyl)-1-(toluene-4-sulfonyl)-1H-imidazole

histamine dichloride
56-92-8

histamine dichloride

Conditions
ConditionsYield
With hydrogenchloride; hydrogen; palladium on activated charcoal In ethanol for 8h;90 mg
β--propionic acid hydrazide

β--propionic acid hydrazide

histamine dichloride
56-92-8

histamine dichloride

Conditions
ConditionsYield
With hydrogenchloride; n-Amyl nitrite Eindampfen des Gemisches und Kochen des Rueckstands mit konz. Salzsaeure;
2-(1H-imidazol-4-yl)ethanol
872-82-2

2-(1H-imidazol-4-yl)ethanol

histamine dichloride
56-92-8

histamine dichloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 336 mg / pyridine / 2 h / -23 °C
2: 180 mg / lithium azide / dimethylformamide / 18 h / 21 °C
3: 90 mg / aq. hydrochloric acid, hydrogen / palladium-charcoal / ethanol / 8 h
View Scheme
histamine hydrochloride
55-36-7

histamine hydrochloride

histamine dichloride
56-92-8

histamine dichloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 34 mg / ethanol, NAD+, liver alcohol dehydrogenase, catalase, diamine oxidase from pea seedling / 48 h / 37 °C / phosphate buffer (pH 7)
2: 336 mg / pyridine / 2 h / -23 °C
3: 180 mg / lithium azide / dimethylformamide / 18 h / 21 °C
4: 90 mg / aq. hydrochloric acid, hydrogen / palladium-charcoal / ethanol / 8 h
View Scheme
With hydrogenchloride In methanol at 30℃;4.11 g
NO-bis-p-tolylsulphonylhistaminol
74294-60-3

NO-bis-p-tolylsulphonylhistaminol

histamine dichloride
56-92-8

histamine dichloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 180 mg / lithium azide / dimethylformamide / 18 h / 21 °C
2: 90 mg / aq. hydrochloric acid, hydrogen / palladium-charcoal / ethanol / 8 h
View Scheme
5-(dimethylamino)naphth-1-ylsulfonyl chloride
605-65-2

5-(dimethylamino)naphth-1-ylsulfonyl chloride

histamine dichloride
56-92-8

histamine dichloride

N,Nim-Didansylhistamine
13285-08-0

N,Nim-Didansylhistamine

Conditions
ConditionsYield
With triethylamine In dichloromethane 1.) 0 deg C, 1 h, 2.) r.t., 20 h;100%
histamine dichloride
56-92-8

histamine dichloride

sodium 4-methyl-2-oxovalerate
4502-00-5

sodium 4-methyl-2-oxovalerate

[2-[(1H-imidazol-4-yl)ethyl]amino]-3-methylpentanoic acid

[2-[(1H-imidazol-4-yl)ethyl]amino]-3-methylpentanoic acid

Conditions
ConditionsYield
silica gel; palladium In methanol100%
zinc(II) chloride hexahydrate

zinc(II) chloride hexahydrate

tri-tert-butoxysilanethiol
690-52-8

tri-tert-butoxysilanethiol

histamine dichloride
56-92-8

histamine dichloride

[2-(1H-imidazol-4-yl-κN3)ethylamine-κN]bis(tri-tert-butoxysilanethiolato-κS)zinc(II)

[2-(1H-imidazol-4-yl-κN3)ethylamine-κN]bis(tri-tert-butoxysilanethiolato-κS)zinc(II)

Conditions
ConditionsYield
With triethylamine In water Et3N added to aq. soln. of ZnCl2*6H2O, histamine*2HCl and Si-compd. added to suspn., flask closed with rubber septum and shaken vigorously for 20 min; solid collected, recrystd. from MeOH/MeCN (4/1);99%
histamine dichloride
56-92-8

histamine dichloride

ethyl 2-acetamino-2-ethoxycarbonyl-6-oxohexanoate
88238-58-8

ethyl 2-acetamino-2-ethoxycarbonyl-6-oxohexanoate

ethyl 2-acetamino-2-ethoxycarbonyl-9-(4-imidazolyl)-7-azanonanoate
88238-59-9

ethyl 2-acetamino-2-ethoxycarbonyl-9-(4-imidazolyl)-7-azanonanoate

Conditions
ConditionsYield
With sodium cyanoborohydride In methanol Ambient temperature;98%
With sodium cyanoborohydride In ethanol Yield given;
N-ethoxycarbonylphthalimide
22509-74-6

N-ethoxycarbonylphthalimide

histamine dichloride
56-92-8

histamine dichloride

2-(2-(1H-imidazol-4-yl)ethyl)isoindoline-1,3-dione
5959-80-8

2-(2-(1H-imidazol-4-yl)ethyl)isoindoline-1,3-dione

Conditions
ConditionsYield
With sodium carbonate In water at 20℃; for 2h;98%
With sodium carbonate In water at 20℃; for 2h;
3,5-di-tert-butyl-2-hydroxybenzaldehyde
37942-07-7

3,5-di-tert-butyl-2-hydroxybenzaldehyde

histamine dichloride
56-92-8

histamine dichloride

2,4-di-tert-butyl-6-{[2-(1H-imidazol-4-yl)-ethylimino]-methyl}-phenol
1374255-34-1

2,4-di-tert-butyl-6-{[2-(1H-imidazol-4-yl)-ethylimino]-methyl}-phenol

Conditions
ConditionsYield
With formic acid; sodium hydrogencarbonate In methanol for 24h; Inert atmosphere; Reflux;98%
histamine dichloride
56-92-8

histamine dichloride

n-decanoyl chloride
112-13-0

n-decanoyl chloride

N-[2-(1H-imidazol-4-yl)ethyl]decanamide

N-[2-(1H-imidazol-4-yl)ethyl]decanamide

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 20℃; for 5h; Cooling with ice;97%
C15H17O(1+)*F6P(1-)

C15H17O(1+)*F6P(1-)

histamine dichloride
56-92-8

histamine dichloride

1-[2-(1H-imidazol-4-yl)ethyl]-2,6-diethyl-4-phenylpyridinium hexafluorophosphate

1-[2-(1H-imidazol-4-yl)ethyl]-2,6-diethyl-4-phenylpyridinium hexafluorophosphate

Conditions
ConditionsYield
Stage #1: histamine dichloride With sodium methylate In methanol; water
Stage #2: C15H17O(1+)*F6P(1-) With acetic acid In methanol; water Reflux;
96%
histamine dichloride
56-92-8

histamine dichloride

isobutyraldehyde
78-84-2

isobutyraldehyde

4-isopropyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine dihydrochloride

4-isopropyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine dihydrochloride

Conditions
ConditionsYield
Stage #1: histamine dichloride With sodium hydroxide In ethanol; water at 0 - 70℃; Large scale;
Stage #2: isobutyraldehyde In ethanol; water at 0 - 76℃; for 10h; Large scale;
Stage #3: With ethanol; acetyl chloride at 0 - 25℃; Large scale;
96%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

histamine dichloride
56-92-8

histamine dichloride

Nα-(tert-butoxycarbonyl)histamine
98870-64-5

Nα-(tert-butoxycarbonyl)histamine

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane; water at 20℃; for 2h; Inert atmosphere;95%
With sodium hydroxide In 1,4-dioxane; water at 20℃; for 2h; pH=12;85%
With triethylamine In methanol; acetonitrile; Petroleum ether
ethyl trifluoroacetate,
383-63-1

ethyl trifluoroacetate,

histamine dichloride
56-92-8

histamine dichloride

trityl chloride
76-83-5

trityl chloride

2,2,2-trifluoro-N-(1-trityl-1H-imidazol-4-ylethyl)acetamide
312937-01-2

2,2,2-trifluoro-N-(1-trityl-1H-imidazol-4-ylethyl)acetamide

Conditions
ConditionsYield
Stage #1: histamine dichloride With N-ethyl-N,N-diisopropylamine In methanol Cooling with ice;
Stage #2: ethyl trifluoroacetate, In methanol at 20℃; Cooling with ice;
Stage #3: trityl chloride With triethylamine In dichloromethane at 0 - 20℃;
94%
Stage #1: histamine dichloride With triethylamine In methanol at 20℃; for 0.166667h;
Stage #2: ethyl trifluoroacetate, In methanol; dichloromethane at 0 - 20℃; for 4h;
Stage #3: trityl chloride With triethylamine In dichloromethane at 20℃;
91%
histamine dichloride
56-92-8

histamine dichloride

4-(2-azidoethyl)-1H-imidazole
1259485-83-0

4-(2-azidoethyl)-1H-imidazole

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; triflic azide; potassium carbonate In methanol; dichloromethane; water at 20℃; pH=8.3;94%
With copper(ll) sulfate pentahydrate; triflic azide; potassium carbonate In methanol; dichloromethane; water at 20℃; for 24h; Inert atmosphere;
C13H13O(1+)*F6P(1-)

C13H13O(1+)*F6P(1-)

histamine dichloride
56-92-8

histamine dichloride

1-[2-(1H-imidazol-4-yl)ethyl]-2,6-dimethyl-4-phenylpyridinium hexafluorophosphate

1-[2-(1H-imidazol-4-yl)ethyl]-2,6-dimethyl-4-phenylpyridinium hexafluorophosphate

Conditions
ConditionsYield
Stage #1: histamine dichloride With sodium methylate In methanol; water
Stage #2: C13H13O(1+)*F6P(1-) With acetic acid In methanol; water Reflux;
94%
histamine dichloride
56-92-8

histamine dichloride

N-t-butyloxycarbonyl-Nε-(2-chlorobenzyloxycarbonyl)lysine pentafluorophenyl ester
78841-25-5

N-t-butyloxycarbonyl-Nε-(2-chlorobenzyloxycarbonyl)lysine pentafluorophenyl ester

Boc-Lys(Z-(2-Cl))-Hia
261784-45-6

Boc-Lys(Z-(2-Cl))-Hia

Conditions
ConditionsYield
With triethylamine In chloroform; N,N-dimethyl-formamide for 20h; Substitution;93%
phthalic anhydride
85-44-9

phthalic anhydride

histamine dichloride
56-92-8

histamine dichloride

2-(2-(1H-imidazol-4-yl)ethyl)isoindoline-1,3-dione
5959-80-8

2-(2-(1H-imidazol-4-yl)ethyl)isoindoline-1,3-dione

Conditions
ConditionsYield
With acetic acid; triethylamine for 2h; Reflux;91.6%
C17H21O(1+)*F6P(1-)

C17H21O(1+)*F6P(1-)

histamine dichloride
56-92-8

histamine dichloride

1-[2-(1H-imidazol-4-yl)ethyl]-2,6-di-iso-propyl-4-phenylpyridinium hexafluorophosphate

1-[2-(1H-imidazol-4-yl)ethyl]-2,6-di-iso-propyl-4-phenylpyridinium hexafluorophosphate

Conditions
ConditionsYield
Stage #1: histamine dichloride With sodium methylate In methanol; water
Stage #2: C17H21O(1+)*F6P(1-) With acetic acid In methanol; water Reflux;
90%
histamine dichloride
56-92-8

histamine dichloride

4-(2-bromoethyl)-1H-imidazole hydrochloride
791634-10-1

4-(2-bromoethyl)-1H-imidazole hydrochloride

Conditions
ConditionsYield
With sulfuric acid; potassium bromide; sodium nitrite at -15℃;90%
VO(OC6H4CHN(CH2C6H5))2

VO(OC6H4CHN(CH2C6H5))2

histamine dichloride
56-92-8

histamine dichloride

salicylaldehyde
90-02-8

salicylaldehyde

VO(C12H13N3O)(C14H11NO)*CH3OH

VO(C12H13N3O)(C14H11NO)*CH3OH

Conditions
ConditionsYield
With NaOH In methanol; ethanol addn. of solid NaOH to suspn. of histamine in methanol, addn. of aldehyde, stirring 15 min, addn. of V complex and ethanol, stirring overnight; precipitate filtered off and washed with ether, elem. anal.;89%
histamine dichloride
56-92-8

histamine dichloride

2,5-dimethoxybenzaldehyde
93-02-7

2,5-dimethoxybenzaldehyde

4-(2,5-dimethoxy-phenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine

4-(2,5-dimethoxy-phenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine

Conditions
ConditionsYield
With sodium hydroxide In methanol for 12h; Heating;88%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

histamine dichloride
56-92-8

histamine dichloride

1-t-Butoxycarbonyl-4-{2-(t-butoxycarbonyl-amino)ethyl}imidazole
127119-12-4

1-t-Butoxycarbonyl-4-{2-(t-butoxycarbonyl-amino)ethyl}imidazole

Conditions
ConditionsYield
Stage #1: histamine dichloride With triethylamine In methanol at 20℃; for 0.5h; Inert atmosphere;
Stage #2: di-tert-butyl dicarbonate In methanol at 20℃; for 1h; Inert atmosphere;
88%
With triethylamine In acetonitrile at 20℃; for 72h;
histamine dichloride
56-92-8

histamine dichloride

3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde
21487-48-9

3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde

4-(3-methyl-1-phenylpyrazol-4-yl)spinaceamine
1206607-01-3

4-(3-methyl-1-phenylpyrazol-4-yl)spinaceamine

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water Heating;88%
histamine dichloride
56-92-8

histamine dichloride

(4-isopropylbenzaldehyde)
122-03-2

(4-isopropylbenzaldehyde)

4-(4-isopropylphenyl)-4,5,6,7-tetrahydro-imidazo[4,5-c]pyridine
303021-39-8

4-(4-isopropylphenyl)-4,5,6,7-tetrahydro-imidazo[4,5-c]pyridine

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water for 1.5h; Heating / reflux;87%
3H-imidazole-4-carboxylic acid
1072-84-0

3H-imidazole-4-carboxylic acid

histamine dichloride
56-92-8

histamine dichloride

3H-imidazole-4-carboxylic acid [2-(1H-imidazol-4-yl)-ethyl]amide

3H-imidazole-4-carboxylic acid [2-(1H-imidazol-4-yl)-ethyl]amide

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane; N,N-dimethyl-formamide at 20℃; for 24h;86%
histamine dichloride
56-92-8

histamine dichloride

4-imidazoleacrylic acid
104-98-3

4-imidazoleacrylic acid

3-(3H-imidazol-4-yl)-N-[2-(1H-imidazol-4-yl)-ethyl]-acrylamide

3-(3H-imidazol-4-yl)-N-[2-(1H-imidazol-4-yl)-ethyl]-acrylamide

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane; N,N-dimethyl-formamide at 20℃; for 24h;86%
histamine dichloride
56-92-8

histamine dichloride

N,N'-bis-Boc-S-methyl-isothiourea
322474-21-5

N,N'-bis-Boc-S-methyl-isothiourea

N',N''-bis(tert-butoxycarbonyl)-N-(2-(1H-imidazol-4-yl)ethyl)guanidine
255061-12-2

N',N''-bis(tert-butoxycarbonyl)-N-(2-(1H-imidazol-4-yl)ethyl)guanidine

Conditions
ConditionsYield
Stage #1: histamine dichloride With sodium carbonate In water at 20℃; for 0.5h;
Stage #2: N,N'-bis-Boc-S-methyl-isothiourea In tetrahydrofuran; water at 55℃; for 24h; Reflux;
86%
((N-(tert-butoxycarbonyl)glycyl)glycyl)glycine
28320-73-2

((N-(tert-butoxycarbonyl)glycyl)glycyl)glycine

histamine dichloride
56-92-8

histamine dichloride

N-tert-butoxycarbonyl-glycyl-glycyl-glycyl-histamine
1267456-25-6

N-tert-butoxycarbonyl-glycyl-glycyl-glycyl-histamine

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In acetonitrile at 20℃; for 12h;85%
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate

Histamine dihydrochloride Chemical Properties

Molecule structure of Histamine dihydrochloride (CAS NO.56-92-8):

IUPAC: 2-(1H-Imidazol-5-yl)ethanamine
Molecular formula: C5H11Cl2N3
Molecular Weight: 184.07 g/mol
EINECS: 200-298-4
Density: 1.14g/cm3
Melting Point: 249-252 °C
Boiling Point: 331 °C at 760 mmHg
Flash Point: 180.3 °C
Water Solubility: 0.1g/mL, clear, colorless
Stability: Stable. Incompatible with strong oxidizing agents. 
Storage Temp.: 2-8 °C
H-Bond Donor: 4
H-Bond Acceptor: 2
Rotatable Bond Count: 2
Tautomer Count: 2
Exact Mass: 183.033003
MonoIsotopic Mass: 183.033003
Topological Polar Surface Area: 54.7
Heavy Atom Count: 10 
Canonical SMILES: C1=C(NC=N1)CCN.Cl.Cl
InChI: InChI=1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H
InChIKey: PPZMYIBUHIPZOS-UHFFFAOYSA-N
Product Categories:Imidazoles & Benzimidazoles;Heterocyclic Compounds;Histidine [His, H];Amino acid salt;Imidazoles & Benzimidazoles

Histamine dihydrochloride Uses

 Histamine dihydrochloride (CAS NO.56-92-8) can be used in biochemical research because it can impact on local immune responses, regulating physiological function in the gut and as a neurotransmitter. It has also been used as substrate in determinating histamine enzyme.

Histamine dihydrochloride Production

 Histamine dihydrochloride can be extracted from Claviceps purpurea, many plants and animals.

Histamine dihydrochloride Toxicity Data With Reference

1.    

orl-mus LD50:2534 mg/kg

    ARTODN    Archives of Toxicology. 2 (1979),371.
2.    

ipr-mus LD50:184 mg/kg

    YKKZAJ    Yakugaku Zasshi. Journal of Pharmacy. 97 (1977),1117.
3.    

scu-mus LDLo:1300 mg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 166 (1932),437.
4.    

ivn-mus LD50:370 mg/kg

    ATSUDG    Archives of Toxicology, Supplement. 2 (1979),371.
5.    

ipr-rbt LDLo:200 mg/kg

    JIDIAQ    Journal of Infectious Diseases. 42 (1928),473.
6.    

ipr-gpg LD50:4602 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 77 (1943),54.
7.    

scu-gpg LD50:1250 µg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 8 (1966),339.
8.    

ivn-gpg LD50:294 µg/kg

    JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 33 (1944),80.
9.    

par-gpg LDLo:570 µg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 211 (1950),328.

Histamine dihydrochloride Consensus Reports

Reported in EPA TSCA Inventory.

Histamine dihydrochloride Safety Profile

Poison by subcutaneous, intravenous, intraperitoneal, and parenteral routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl and NOx. See also HISTAMINE.
Hazard Codes: HarmfulXn, IrritantXi
Risk Statements:36/37/38-42/43-42-22
22:(Harmful if swallowed)
36/37/38: (Irritating to the eyes piratory system and skin)
42/43:(May cause sensitization by inhalation and skin contact)
42:(May cause sensitization by inhalation)
Safety Statements:22-26-36/37/39-45-37-36/37
22:(Do not breathe dust)
26: (In case of contact with eyes,rinse immediately with plenty of water and seek medical advice)
36/37/39:(Wear suitable protective clothing, gloves and eye/face protection)
45:(In case of accident or if you feel unwell, seek medical advice immediately (show label where possible))
37:(Wear suitable gloves)
36/37:(Wear suitable protective clothing and gloves)
WGK Germany:2
RTECS:MS1575000
F:1-8-9
Hazard Note:Irritant

Histamine dihydrochloride Specification

 Histamine dihydrochloride (CAS NO.56-92-8) is also named as 2-(1H-Imidazol-4-yl)ethanamine dihydrochloride ; 2-(1H-Imidazol-4-yl)ethylamine dihydrochloride ; 4-(2-Aminoethyl)imidazole dihydrochloride ; AI3-24394 ; Bichlorhydrate d'histamine ; Bichlorhydrate d'histamine [French] ; Ceplene ; Histamine HCl ; Histamine chloride ; Histamine dichloride ; Histamine dihydrochloride ; NSC 257873 ; Peremin ; UNII-3POA0Q644U . Histamine dihydrochloride (CAS NO.56-92-8) is white powder.

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