The Hydroxypropyl cellulose, with the cas registry number 9004-64-2, has the systematic name of Cellulose, 2-hydroxypropyl ether. Its product categories are various, including Cellulose; Natural Polymers; Polymer Science; HU - HZPolymer Standards; Hydroxypropyl cellulose; Water Soluble Polymers; Alphabetic; H; API's. What's more, this chemical could be produced by the reaction of alkali and epoxypropane. This is a kind of white particle or fabrous powder with no odour but with thermoplasticity. It is soluble in ehanol while insoluble in diethyl ether and could become transparent to oyster white viscoloid colloidal solution. Besides, this chemical is stable chemically but combustible and incompatible with strong oxidizing agents. While using this chemical, please do avoid contacting with skin and eyes.
Uses of Hydroxypropyl cellulose:
It is widely applied in many fields. It could be usually used in pharmaceutic for being the cementing agent and membrance-forming agent in medicines; It could also be used as the film-forming agent, dispersing agent, stabilizing agent and thickening agent in cosmetic, painting and printing ink industries.
The toxicity data of Hydroxypropyl cellulose is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | > 25gm/kg (25000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. | |
mouse | LD50 | intravenous | > 500mg/kg (500mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. | |
mouse | LD50 | oral | > 5gm/kg (5000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. | |
rat | LD50 | intraperitoneal | > 25gm/kg (25000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. | |
rat | LD50 | intravenous | 250mg/kg (250mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. | |
rat | LD50 | oral | 10200mg/kg (10200mg/kg) | FAO Nutrition Meetings Report Series. Vol. 46A, Pg. 131, 1969. |
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