L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid supplier

Name
L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
EINECS -0
CAS No. 74163-81-8
Article Data35
CAS DataBase
Density 1.225 g/cm³
Solubility
Melting Point 300 °C
Formula C₁₀H₁₁NO₂
Boiling Point 372 °C at 760 mmHg
Molecular Weight 177.203
Flash Point 178.8 °C
Transport Information
Appearance white to light yellow crystal powder
Safety 26-36/37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms 3-Isoquinolinecarboxylicacid, 1,2,3,4-tetrahydro-, (S)-;(-)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylicacid;(3S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid;(S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid;
PSA 49.33000
LogP 1.11430

Synthetic route

: 50-00-0
formaldehyd

: 63-91-2
L-phenylalanine

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
With hydrogenchloride In water at 90℃; for 12h; Pictet-Spengler Synthesis;	98%
With hydrogenchloride In water at 90℃; for 12h;	98%
With hydrogenchloride at 85℃; for 9h; Pictet-Spengler condensation;	95%

: 143767-56-0
(-)-menthyl (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
With sodium hydroxide In methanol for 6h; Ambient temperature;	94%

: 77497-96-2
(S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, phenylmethylester

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
With sodium hydroxide In water for 15h; Ambient temperature;	81%
With hydrogen; palladium on activated charcoal In ethanol; water; acetic acid for 4h; Ambient temperature;	75.4%

: 367952-43-0
(10aS)-3,3-Bis(trifluoromethyl)-1-oxo-(1,2,3,4-tetrahydroisoquinolino)[2,3-c]oxazolidine

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
With water In isopropyl alcohol at 20℃;	72%

: 67123-97-1
(R,S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
With ammonium hydroxide; borane-ammonia complex; recombinant Escherichia coli BL21 (DE3) cells expressed D-amino acid oxidase from Fusarium solani M-0718 In water at 30℃; pH=8; Resolution of racemate; Enzymatic reaction; enantioselective reaction;	68%

: 123053-49-6
(3R,10bS)-3-tert-Butyl-2-methyl-2,3,6,10b-tetrahydro-5H-imidazo[5,1-a]isoquinolin-1-one

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
With hydrogenchloride; Dowex 50-WX8; acetic acid In water; toluene at 103℃; for 126h;	67%

: 307304-56-9
(3'S,4R,5S)-1,5-dimethyl-4-phenyl-3-(1',2',3',4'-tetrahydro-3'-isoquinolinylcarbonyl)-2-imidazolidinone

A: 74163-81-8
L-Tic-OH

B: 103733-65-9
(3R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

Conditions

Conditions	Yield
With water for 12h; Hydrolysis; epimerization; Heating; Title compound not separated from byproducts.;

: 15912-55-7, 41234-43-9, 55857-63-1
ethyl 1,2,3,4-tetrahydroisoquinoline-3-(S)-carboxylate

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
With chicken liver acetone; water pH=7.5;

: 57060-86-3
1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
With chicken liver acetone; water for 2h; pH=7.5;

: (+/-)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid butyl ester

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
With chicken liver acetone; water pH=7.5;

: 91-13-4
α,α'-dibromo-o-xylene

chiral Ni complex of Schiff base of glycine and BPB: chiral Ni complex of Schiff base of glycine and BPB

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
Stage #1: α,α'-dibromo-o-xylene; chiral Ni complex of Schiff base of glycine and BPB With sodium hydroxide In acetonitrile at 20℃; for 0.666667h; Stage #2: In hydrogenchloride; methanol at 50℃; for 0.333333h; Stage #3: In ammonium hydroxide

: 63-91-2
L-phenylalanine

Gly-NH-Rink-resinEt halide: Gly-NH-Rink-resinEt halide

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 91 percent / dimethylsulfoxide 2: 65 percent / SOCl2 3: BF3*OEt2 / 20 °C 4: 72 percent / H2O / propan-2-ol / 20 °C View Scheme
Multi-step reaction with 3 steps 1: 91 percent / dimethylsulfoxide 2: 82 percent / TFA / CHCl3 / 0.5 h 3: 72 percent / H2O / propan-2-ol / 20 °C View Scheme

: 150582-52-8
(4S)-4-Benzyl-2,2-bis(trifluoromethyl)-1,3-oxazolidin-5-one

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 65 percent / SOCl2 2: BF3*OEt2 / 20 °C 3: 72 percent / H2O / propan-2-ol / 20 °C View Scheme
Multi-step reaction with 2 steps 1: 82 percent / TFA / CHCl3 / 0.5 h 2: 72 percent / H2O / propan-2-ol / 20 °C View Scheme

: 367952-46-3
(4S)-4-Benzyl-2,2-bis(trifluoromethyl)-3-chloromethyl-1,3-oxazolidin-5-one

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: BF3*OEt2 / 20 °C 2: 72 percent / H2O / propan-2-ol / 20 °C View Scheme

: 143767-54-8
(+/-)-2-acetyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 86 percent / 6 N aq. HCl / 4 h / Heating 2: 83 percent / p-TsOH*H2O / toluene / 30 h / Heating 3: 94 percent / NaOH / methanol / 6 h / Ambient temperature View Scheme

: 612-12-4
o-Xylylene dichloride

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: NaOMe / 4 h / Heating 2: 6 N aq. HCl / 4 h / Heating 3: 83 percent / p-TsOH*H2O / toluene / 30 h / Heating 4: 94 percent / NaOH / methanol / 6 h / Ambient temperature View Scheme
Multi-step reaction with 5 steps 1: NaOMe / 4 h / Heating 2: 1.) KOH, 2.) 2 N HCl / 1.) MeOH, H2O, reflux, 4 h, 2.) EtOAc, pH 1 3: 86 percent / 6 N aq. HCl / 4 h / Heating 4: 83 percent / p-TsOH*H2O / toluene / 30 h / Heating 5: 94 percent / NaOH / methanol / 6 h / Ambient temperature View Scheme

: 143767-55-9
dimethyl 2-acetyl-1,2,3,4-tetrahydro-3,3-isoquinolinedicarboxylate

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 6 N aq. HCl / 4 h / Heating 2: 83 percent / p-TsOH*H2O / toluene / 30 h / Heating 3: 94 percent / NaOH / methanol / 6 h / Ambient temperature View Scheme
Multi-step reaction with 4 steps 1: 1.) KOH, 2.) 2 N HCl / 1.) MeOH, H2O, reflux, 4 h, 2.) EtOAc, pH 1 2: 86 percent / 6 N aq. HCl / 4 h / Heating 3: 83 percent / p-TsOH*H2O / toluene / 30 h / Heating 4: 94 percent / NaOH / methanol / 6 h / Ambient temperature View Scheme

: 91-13-4
α,α'-dibromo-o-xylene

sodium-compound of (+-)-acetylamino-cyano-acetic acid ethyl ester: sodium-compound of (+-)-acetylamino-cyano-acetic acid ethyl ester

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 75 percent / NaOMe / 4 h / Heating 2: 6 N aq. HCl / 4 h / Heating 3: 83 percent / p-TsOH*H2O / toluene / 30 h / Heating 4: 94 percent / NaOH / methanol / 6 h / Ambient temperature View Scheme
Multi-step reaction with 5 steps 1: 75 percent / NaOMe / 4 h / Heating 2: 1.) KOH, 2.) 2 N HCl / 1.) MeOH, H2O, reflux, 4 h, 2.) EtOAc, pH 1 3: 86 percent / 6 N aq. HCl / 4 h / Heating 4: 83 percent / p-TsOH*H2O / toluene / 30 h / Heating 5: 94 percent / NaOH / methanol / 6 h / Ambient temperature View Scheme

: 150-30-1
Phenylalanine

α-ureido-β-phenyl-propionic acid: α-ureido-β-phenyl-propionic acid

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 69 percent / conc. HCl View Scheme

: 50-00-0
formaldehyd

aqueous NH4OH: aqueous NH4OH

: 63-91-2
L-phenylalanine

: 7664-93-9
sulfuric acid

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
In hydrogenchloride; ethanol; water

...Expand

: 50-00-0
formaldehyd

: 1009-67-2, 5628-72-8, 14367-54-5, 14367-67-0
2-methyl-3-phenylpropionic acid

: 74163-81-8
L-Tic-OH

Conditions

Conditions	Yield
With hydrogenchloride; water Reflux;

: 67-56-1
methanol

: 74163-81-8
L-Tic-OH

: 79815-19-3
methyl (3S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate

Conditions

Conditions	Yield
With thionyl chloride	100%
With thionyl chloride at 0 - 20℃;	96%
With sulfuric acid for 12h; Reflux;	95%

: 541-41-3
chloroformic acid ethyl ester

: 74163-81-8
L-Tic-OH

: 104882-53-3
2-carboethoxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid

Conditions

Conditions	Yield
With sodium hydrogencarbonate In tetrahydrofuran; water 1.) 0 deg C to room temperature, 2.) room temperature, 3 h;	100%

: 24424-99-5
di-tert-butyl dicarbonate

: 74163-81-8
L-Tic-OH

: 115962-35-1, 144069-68-1, 78879-20-6
(3S)-2-tert-butoxycarbonyl-1,2,3,4-tetrahydroisoquinole-3-carboxylic acid

Conditions

Conditions	Yield
With sodium hydrogencarbonate In 1,4-dioxane; water at 20℃; for 144h;	100%
With sodium hydrogencarbonate In 1,4-dioxane; water at 20℃; for 144h; Time;	100%
With sodium hydrogencarbonate In 1,4-dioxane; water at 20℃; for 144h; Concentration;	100%

: 67-56-1
methanol

: 74163-81-8
L-Tic-OH

: 78183-55-8
(S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, methyl ester, hydrochloride

Conditions

Conditions	Yield
With thionyl chloride	100%
With thionyl chloride at 0 - 40℃; for 21h; Inert atmosphere;	99%
With thionyl chloride at 0 - 40℃; for 21h; Inert atmosphere;	99%
With chloro-trimethyl-silane at 70℃; for 2h; Reflux;

: 74163-81-8
L-Tic-OH

: 501-53-1
benzyl chloroformate

: 79261-58-8
(S)-3,4-dihydro-1H-isoquinoline-2,3-dicarboxylic acid 2-benzyl ester

Conditions

Conditions	Yield
With sodium hydroxide In 1,4-dioxane; water at 20℃; for 16h;	99%
With sodium hydroxide In 1,4-dioxane; water at 0 - 20℃; for 16.5h;	99%
With sodium hydrogencarbonate In water at 20℃; for 1.5h;	97%

: 74163-81-8
L-Tic-OH

: 18881-17-9, 62855-02-1, 62928-94-3, 63006-93-9
(S)-3-hydroxymethyl-1,2,3,4-tetrahydroisoquinoline

Conditions

Conditions	Yield
With dimethylsulfide borane complex; boron trifluoride diethyl etherate In tetrahydrofuran for 6h; Reduction; Heating;	96%
With lithium aluminium tetrahydride In tetrahydrofuran for 6h; Heating;	86%
With dimethylsulfide borane complex; boron trifluoride diethyl etherate In tetrahydrofuran	78%

: 75-44-5
phosgene

: 74163-81-8
L-Tic-OH

: 186606-17-7
(10aS)-10,10a-dihydro[1,3]oxazolo[3,4-b]isoquinoline-1,3,(5H)-dione

Conditions

Conditions	Yield
In tetrahydrofuran; dichloromethane at -30 - 20℃;	95%

: 74163-81-8
L-Tic-OH

: 77141-07-2
(S)-7-nitro-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

Conditions

Conditions	Yield
With sulfuric acid; nitric acid at -20℃; for 0.5h;	93%
With sulfuric acid; nitric acid at -10℃; for 3.5h;	90%
With sulfuric acid; potassium nitrate at 5 - 20℃;

: 50-00-0
formaldehyd

: 74163-81-8
L-Tic-OH

: (S)-2-methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

Conditions

Conditions	Yield
With formic acid for 4h; Reflux;	93%

: 50-00-0
formaldehyd

: 74163-81-8
L-Tic-OH

: (S)-2-methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride

Conditions

Conditions	Yield
Stage #1: formaldehyd; L-Tic-OH With formic acid In water for 4h; Reflux; Stage #2: With hydrogenchloride In water Cooling with ice;	93%

: 64-17-5
ethanol

: 74163-81-8
L-Tic-OH

: 15912-55-7
ethyl (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

Conditions

Conditions	Yield
With thionyl chloride Reflux;	91%
With thionyl chloride
With sulfuric acid at 80℃; for 20h; Inert atmosphere;

: 7677-24-9
trimethylsilyl cyanide

: 100-52-7
benzaldehyde

: 74163-81-8
L-Tic-OH

: 1346425-09-9
2-benzyl-1,2,3,4-tetrahydroisoquinoline-3-carbonitrile

Conditions

Conditions	Yield
In butan-1-ol at 200℃; for 0.166667h; decarboxylative Strecker reaction; Microwave irradiation; enantioselective reaction;	91%

...Expand

: 35661-60-0
Fmoc-Leu-OH

: 71989-31-6
Fmoc-Pro-OH

: 35661-40-6
N-Fmoc L-Phe

: 71989-16-7
Fmoc-Asn-OH

: 91000-69-0
Fmoc-L-Arg-OH

: 74163-81-8
L-Tic-OH

: 76-05-1
trifluoroacetic acid

: C46H69N15O8*C2HF3O2

Conditions

Conditions	Yield
Stage #1: Fmoc-Asn-OH With benzotriazol-1-ol; diisopropyl-carbodiimide In N,N-dimethyl-formamide for 2h; Stage #2: With piperidine In N,N-dimethyl-formamide for 0.333333h; Stage #3: Fmoc-Leu-OH; Fmoc-Pro-OH; N-Fmoc L-Phe; Fmoc-L-Arg-OH; L-Tic-OH; trifluoroacetic acid Further stages;	89%

...Expand

: 12354-84-6, 12354-85-7
bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]

: 74163-81-8
L-Tic-OH

: chloro-pentamethylcyclopentadienyltetrahydroisoquinolinecarboxylato-iridium

Conditions

Conditions	Yield
With CH3ONa In methanol; dichloromethane (Ar); addn. of a soln. of MeONa to a soln. of ligand in methanol, addn. to a soln. of iridium complex in CH2Cl2, stirring for 3 h; evapn., dissolving in CH2Cl2, filtration, concn., addn. of Et2O, filtration, washing with Et2O, pentane, drying in vac.; elem. anal.;	85%

: 6046-93-1
copper(II) acetate monohydrate

: 74163-81-8
L-Tic-OH

: bis(tetrahydroisoquinolinecarboxylato)copper

Conditions

Conditions	Yield
In methanol (Ar); addn. of ligand to a soln. of copper salt in methanol; isolation, washing with methanol, ether, drying in vac.; elem. anal.;	84%

: 74163-81-8
L-Tic-OH

: 71-36-3
butan-1-ol

: butyl (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

Conditions

Conditions	Yield
With thionyl chloride at 120℃; for 16h; Inert atmosphere;	84%

: 74163-81-8
L-Tic-OH

: 877932-98-4
N-(1-ethoxycarbonyl-3-phenylpropyl)-L-alanine

: 129178-93-4
L-alanine acid chloride

: 85441-61-8
quinapril

Conditions

Conditions	Yield
With benzenesulfonamide; phosphorus pentachloride; triethylamine In n-heptane; dichloromethane; water	83.9%

...Expand

: 74163-81-8
L-Tic-OH

: 6624-49-3
isoquinoline-3-carboxylic acid

Conditions

Conditions	Yield
With potassium permanganate In N,N-dimethyl-formamide at 0 - 20℃; for 100.5h; Inert atmosphere;	83%
With potassium permanganate	83%
With potassium permanganate In N,N-dimethyl-formamide at 20℃; for 72h; Cooling with ice;	62%

: 3375-31-3
palladium diacetate

: 74163-81-8
L-Tic-OH

: bis(tetrahydroisoquinolinecarboxylato)palladium

Conditions

Conditions	Yield
In methanol (Ar); addn. of ligand to a soln. of copper salt in methanol; isolation, washing with methanol, ether, drying in vac.; elem. anal.;	81%

: 1070-19-5
N-(tert-butyloxycarbonyl) azide

: 74163-81-8
L-Tic-OH

: 115962-35-1, 144069-68-1, 78879-20-6
(3S)-2-tert-butoxycarbonyl-1,2,3,4-tetrahydroisoquinole-3-carboxylic acid

Conditions

Conditions	Yield
With triethylamine In N,N-dimethyl-formamide at 20℃; for 48h; pH=10;	80%

: 112-77-6
(Z)-9-octadecenoyl chloride

: 74163-81-8
L-Tic-OH

: (S)-2-oleoyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

Conditions

Conditions	Yield
With potassium carbonate In water; acetone at 0 - 20℃;	78%

: 23147-58-2, 110822-84-9, 110822-85-0
glycolaldehyde dimer

: 119072-55-8, 7188-38-7
tert-butylisonitrile

: 74163-81-8
L-Tic-OH

: 1-oxo-1,3,4,9,9a,10-hexahydro-2-oxa-4a-aza-anthracene-4-carboxylic acid tert-butylamide

Conditions

Conditions	Yield
In 2,2,2-trifluoroethanol at -40 - 20℃; for 12h; Ugi reaction;	77%

...Expand

: 52462-29-0
[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2

: 74163-81-8
L-Tic-OH

: chloro-p-cymenetetrahydroisoquinolinecarboxylato-ruthenium

Conditions

Conditions	Yield
With CH3ONa In methanol; dichloromethane (Ar); addn. of a soln. of MeONa to a soln. of ligand in methanol, addn. to a soln. of ruthenium complex in CH2Cl2, stirring for 3 h; evapn., dissolving in CH2Cl2, filtration through celite, concn., addn. to pentane, filtration, washing with pentane, drying in vac.; elem. anal.;	77%

: 15692-96-3
trans-di-μ-chloro-dichlorobis(triethylphosphine)diplatinum

: 74163-81-8
L-Tic-OH

: chloro-triethylphosphanetetrahydroisoquinolinecarboxylato-platinum

Conditions

Conditions	Yield
With CH3ONa In methanol; dichloromethane (Ar); addn. of a soln. of MeONa to a soln. of ligand in methanol, addn. to a soln. of platinum complex in CH2Cl2, stirring for 3 h; evapn., dissolving in CH2Cl2, filtration, addn. of pentane, washing withpentane, drying in vac.; elem. anal.;	77%

: dichlorobis(triethylphosphine)-μ-dichlorodipalladium(II)

: 74163-81-8
L-Tic-OH

: chloro-triethylphosphanetetrahydroisoquinolinecarboxylato-palladium

Conditions

Conditions	Yield
With CH3ONa In methanol; dichloromethane (Ar); addn. of a soln. of MeONa to a soln. of ligand in methanol, addn. to a soln. of palladium complex in CH2Cl2, stirring for 3 h; evapn., dissolving in CH2Cl2, filtration, evapn., addn. of pentane, cooling to -20°C, washing with pentane, drying in vac.; elem. anal.;	76%

: 13139-17-8
N-(Benzyloxycarbonyloxy)succinimide

: 74163-81-8
L-Tic-OH

: 79261-58-8
(S)-3,4-dihydro-1H-isoquinoline-2,3-dicarboxylic acid 2-benzyl ester

Conditions

Conditions	Yield
With sodium hydroxide In N,N-dimethyl-formamide at 0 - 20℃; for 27h;	74.7%

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Chemical Properties

IUPAC Name: (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Synonyms of L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid (CAS NO.74163-81-8): 3-Isoquinolinecarboxylicacid, 1,2,3,4-tetrahydro-, (S)- ; (3S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid ; S-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
CAS NO: 74163-81-8
Molecular Formula: C₁₀H₁₁NO₂
Molecular Weight: 177.20
Molecular Structure:
H bond acceptors: 3
H bond donors: 2
Freely Rotating Bonds: 1
Polar Surface Area: 29.54 Å²
Index of Refraction: 1.576
Molar Refractivity: 47.88 cm³
Molar Volume: 144.5 cm³
Surface Tension: 48.2 dyne/cm
Density: 1.225 g/cm³
Flash Point: 178.8 °C
Enthalpy of Vaporization: 65.31 kJ/mol
Boiling Point: 372 °C at 760 mmHg
Vapour Pressure: 3.41E-06 mmHg at 25°C
Melting point: 300 °C
Alpha: -157.4 º (24°C)
Storage temp: Store at 0-5°C
Appearance: white to light yellow crystal powder
Product Categories of L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid (CAS NO.74163-81-8): Amino Acids;Carboxylic Acids;Quinolines, Isoquinolines & Quinoxalines;chiral;(intermediate of quinapril);Carboxylic Acids;Quinolines, Isoquinolines & Quinoxalines;IsoquinolinesPeptide Synthesis;Chiral Building Blocks;Heterocyclic Building Blocks;Others;Unnatural Amino Acid Derivatives;Peptide Synthesis;a-amino

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Safety Profile

Safety Information about L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid (CAS NO.74163-81-8):
Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany: 3

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Specification

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Store in a cool, dry place. Store in a tightly closed container.

Product Name

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

Synthetic route

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Chemical Properties

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Safety Profile

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Specification

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