N-Bromosuccinimide supplier

Name
N-Bromosuccinimide
EINECS 204-877-2
CAS No. 128-08-5
Article Data40
CAS DataBase
Density 2.042 g/cm³
Solubility Soluble in acetone, tetrahydrofuran, dimethyl formamide, dimethyl sulfoxide and acetonitrile. Slightly soluble in water and acetic acid. Insoluble in ether, hexane and carbon tetrachloride.
Melting Point 173- 176°C
Formula C₄H₄BrNO₂
Boiling Point 221.4 °C at 760 mmHg
Molecular Weight 177.985
Flash Point 87.7 °C
Transport Information UN 3261 8/PG 2
Appearance white to off-white powder
Safety 26-36/37/39-45-37/39
Risk Codes 22-34-36/37/38
Molecular Structure
Hazard Symbols C,Xn
Synonyms N-Bromosuccinimide;N-bromobutanimide;1-Bromopyrrolidine-2,5-dione;1-bromopyrrolidine-2,5-dione;
PSA 37.38000
LogP 0.38320

Synthetic route

: 123-56-8
Succinimide

: 128-08-5
N-Bromosuccinimide

Conditions

Conditions	Yield
With hydrogenchloride; sodium chlorite; sodium bromide In water at 0 - 25℃; for 1.5h; Temperature;	96%
With sodium bromate; sulfuric acid; hydrogen bromide In water for 0.166667h; Ambient temperature;	95%
With [bis(acetoxy)iodo]benzene In tetrachloromethane at 20℃; Solvent;	94%

: 123-56-8
Succinimide

: 79-15-2
N-bromoacetamide

: 128-08-5
N-Bromosuccinimide

: 128-09-6
N-chloro-succinimide

: 128-08-5
N-Bromosuccinimide

Conditions

Conditions	Yield
With tetraethylammonium bromide halogen exchange durin complex formation between an N-halogensuccinimide and quaternary ammonium halide;
With water; sodium bromide

: 82815-39-2
benzotelluracyclopentane bromide succinimide

A: 128-08-5
N-Bromosuccinimide

B: 1,1-dibromo-3,4-benzo-1-telluracyclopentane

Conditions

Conditions	Yield
With bromine Te-N cleavage;

: 123-56-8
Succinimide

: 7726-95-6
bromine

: furan-2,3,5(4H)-trione pyridine (1:1)

: 128-08-5
N-Bromosuccinimide

...Expand

: 123-56-8
Succinimide

hypobromous acid: hypobromous acid

: 128-08-5
N-Bromosuccinimide

: 123-56-8
Succinimide

A: 128-08-5
N-Bromosuccinimide

B H2O: H2O

Conditions

Conditions	Yield
Equilibrium constant;

: 123-56-8
Succinimide

A: 128-08-5
N-Bromosuccinimide

B HBr: HBr

Conditions

Conditions	Yield
With bromine Equilibrium constant;

: 2-(4-methylphenyl)-2-(N-bromo-p-toluene-sulfonamide)-1-bromo-ethane

: 123-56-8
Succinimide

A: 128-08-5
N-Bromosuccinimide

B: 2-bromo-1-(4-methylphenyl)-1-(p-toluenesulfonamido)ethane

Conditions

Conditions	Yield
In dichloromethane-d2

...Expand

: C21H16BrS(1+)*C4H4NO2(1-)

A: 128-08-5
N-Bromosuccinimide

B: 74067-58-6
1-methylthiotriptycene

Conditions

Conditions	Yield
In dichloromethane-d2 at 22℃; Equilibrium constant; Inert atmosphere; Schlenk technique;

: 128-08-5
N-Bromosuccinimide

: 31199-21-0
dioxa-3,5 exo p-nitrophenyl-4 syn tricyclo<5.2.1.02,6>decane

: 77085-46-2
1-[(1S,2R,6S,7R)-4-(4-Nitro-phenyl)-3,5-dioxa-tricyclo[5.2.1.02,6]dec-4-yl]-pyrrolidine-2,5-dione

Conditions

Conditions	Yield
In tetrachloromethane for 1h; Heating;	100%

: 128-08-5
N-Bromosuccinimide

: 443694-36-8
5-tert-butyl-2-methoxy-3H-azepine

: 5-bromo-4-t-butyl-5,6-dihydro-7-methoxy-2-succinimidyl-2H-azepine

Conditions

Conditions	Yield
In dichloromethane at -98℃;	100%

: 20662-84-4
2,4,5-trimethyloxazole

: 128-08-5
N-Bromosuccinimide

: 141567-40-0
5-(bromomethyl)-2,4-dimethyloxazole

Conditions

Conditions	Yield
With dibenzoyl peroxide In tetrachloromethane for 1h; Heating / reflux;	100%

: 128-08-5
N-Bromosuccinimide

: 511277-65-9
3-benzyloxy-4-ethyl-1-methoxybenzene

: 511277-67-1
5-benzyloxy-2-bromo-4-ethyl-1-methoxybenzene

Conditions

Conditions	Yield
In tetrachloromethane for 16h; silica gel 60 (EM Science);	100%

: 128-08-5
N-Bromosuccinimide

: N-bromosuccinamide

: 122670-62-6
2-Bromo-5-(trifluoromethyl)-6-methoxy-1-naphthalene-carboxylic acid

: 122670-68-2
2-chloro-6-methoxy-1-methyl-5-(trifluoromethyl)naphthalene

: 94-36-0
dibenzoyl peroxide

: 122670-63-7
1-bromomethyl-2-chloro-6-methoxy-5-trifluoromethylnaphthalene

Conditions

Conditions	Yield
In tetrachloromethane	100%

...Expand

: 128-08-5
N-Bromosuccinimide

: 122670-67-1
2-bromo-6-methoxy-1-methyl-5-(trifluoromethyl)naphthalene

: 122670-66-0
2-Bromo-1-(bromomethyl)-5-(trifluoromethyl)-6-methoxynaphthalene

Conditions

Conditions	Yield
With dibenzoyl peroxide In tetrachloromethane	100%

: 128-08-5
N-Bromosuccinimide

: N-bromosuccinamide

: 122670-68-2
2-chloro-6-methoxy-1-methyl-5-(trifluoromethyl)naphthalene

: 94-36-0
dibenzoyl peroxide

: 122670-63-7
1-bromomethyl-2-chloro-6-methoxy-5-trifluoromethylnaphthalene

Conditions

Conditions	Yield
In tetrachloromethane	100%

...Expand

: 128-08-5
N-Bromosuccinimide

: 122670-67-1
2-bromo-6-methoxy-1-methyl-5-(trifluoromethyl)naphthalene

: 122670-63-7
1-bromomethyl-2-chloro-6-methoxy-5-trifluoromethylnaphthalene

: 122670-66-0
2-Bromo-1-(bromomethyl)-5-(trifluoromethyl)-6-methoxynaphthalene

Conditions

Conditions	Yield
With dibenzoyl peroxide In tetrachloromethane	100%

...Expand

: 128-08-5
N-Bromosuccinimide

: 3-ethoxy-4-methyl-5-(thien-2-yl)isoxazole

: 4-bromomethyl-3-ethoxy-5-(thien-2-yl)isoxazole

Conditions

Conditions	Yield
In tetrachloromethane	100%

: 128-08-5
N-Bromosuccinimide

: 31378-26-4, 31378-27-5, 14284-93-6
tris(2,4-pentanedionato)ruthenium(III)

: tris(3-bromo-2,4-pentanedionato)ruthenium(III)

Conditions

Conditions	Yield
In chloroform column (aluminumoxid), evapn., recrystn. (EtOH), elem. anal.;	100%
In chloroform ratio of succinimide to (Ru(OCCH3CHCCH3O)3) is 3.0;; column chromatographic separation (Al2O3 90), eluent was evaporated to dryness, residue recrystd. from ethanol, crystals dried under vacuum, elem. anal., UV, NMR;

: 128-08-5
N-Bromosuccinimide

: 167033-03-6
((C2H5)2C2B4H4)Nb(Cl)2(C5H5)

: 266323-95-9
C5H5Cl2Nb((C2H5)2C2B4H3Br)

Conditions

Conditions	Yield
In tetrahydrofuran Nb-complex was dissolved in THF, ligand was added, shaken for 5 min under inert atm.; after 10 min solvent was removed by rotary evaporator, residue was redissolved in CH2Cl2, flash-chromd. on silica, solvent was removed; elem. anal.;	100%

: 128-08-5
N-Bromosuccinimide

: 1254037-04-1
((Me3Si)2CH)3C6H2(H)SnC5H6

: 1254037-01-8
((Me3Si)2CH)3C6H2(Br)SnC5H6

Conditions

Conditions	Yield
In benzene addn. of NBS in C6H6 to Sn compd. at room temp., stirring for 1 h;	100%

: 128-08-5
N-Bromosuccinimide

: C18H17N5O2

: C18H16BrN5O2

Conditions

Conditions	Yield
In tetrahydrofuran at -78℃; for 1h; Cooling with acetone-dry ice;	100%

: 128-08-5
N-Bromosuccinimide

: C19H16N2O2

: C19H15BrN2O2

Conditions

Conditions	Yield
In tetrahydrofuran at -78℃; for 1h; Cooling with acetone-dry ice;	100%

: 128-08-5
N-Bromosuccinimide

: C16H13N5O

: C16H12BrN5O

Conditions

Conditions	Yield
In tetrahydrofuran at -78℃; for 1h; Cooling with acetone-dry ice;	100%

: 1-formyl-5-(4-(2-(triisopropylsilyl)ethynyl)phenyl)dipyrromethane

: 128-08-5
N-Bromosuccinimide

: C27H33BrN2OSi

Conditions

Conditions	Yield
In tetrahydrofuran at -78℃; for 1h; Cooling with acetone-dry ice;	100%

: 128-08-5
N-Bromosuccinimide

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 39859-36-4
2-amino-5-bromobenzophenone

Conditions

Conditions	Yield
In dichloromethane at 0 - 20℃;	100%

: 17084-13-8
potassium hexafluorophosphate

: 128-08-5
N-Bromosuccinimide

: C150H106Ir3N18Ru(5+)*5F6P(1-)

: C150H102Br4Ir3N18Ru(5+)*5F6P(1-)

Conditions

Conditions	Yield
Stage #1: N-Bromosuccinimide; C150H106Ir3N18Ru(5+)*5F6P(1-) In acetonitrile at 20℃; for 38h; Stage #2: potassium hexafluorophosphate In water	100%

...Expand

: 128-08-5
N-Bromosuccinimide

: 5,15-bis(mesityl)norcorrolatonickel(II)

: C38H30Br2N4Ni

Conditions

Conditions	Yield
With pyridine In chloroform-d1 at 0℃;	100%
In methanol; dichloromethane at 20℃; for 0.333333h;	96%

: 128-08-5
N-Bromosuccinimide

: 1701-93-5
silver thiocyanate

: 163276-49-1
1-thiocyanatopyrrolidine-2,5-dione

Conditions

Conditions	Yield
In dichloromethane	100%

: 128-08-5
N-Bromosuccinimide

: 211803-10-0
N,N-dibutyl-(3,3,3-trifluoro-1-propynyl)amine

: 353301-02-7
N-[2-Bromo-1-(N',N'-dibutylamino)-3,3,3-trifluoro-1-propenyl]succinimide

Conditions

Conditions	Yield
With 4 A molecular sieve In acetonitrile at 20℃; for 1h;	99%

: 128-08-5
N-Bromosuccinimide

: 7424-72-8
9-(naphthyl-2-yl)anthracene

: 474688-73-8
9-bromo-10-(2-naphtyl)-anthracene

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide	99%

: 128-08-5
N-Bromosuccinimide

: (C5(CH3)5)Co((CH3CH2)2C2B3H4Br)

: (C5(CH3)5)Co((CH3CH2)2C2B3H3Br2)

Conditions

Conditions	Yield
In tetrahydrofuran dissoln. of Co-complex in THF, addn. of 1.5 equiv. of succinimide-compd., stirring for < 5 min (color change from orange to dark orange-brown);	99%

: 128-08-5
N-Bromosuccinimide

: [(1-pyrrolylimido)F(dpe)2tungsten](BF4)

: W(((C6H5)2PCH2)2)2FNN(CH)3CBr(1+)*BF4(1-)*ClCH2CH2Cl=[W(((C6H5)2PCH2)2)2FNN(CH)3CBr]BF4*ClCH2CH2Cl

Conditions

Conditions	Yield
In tetrahydrofuran (N2); stirring (-50°C, 9 h), addn. (5% aq. Na2S2O3); washing (5% aq. Na2S2O3, 5% NH4BF4), drying (MgSO4), evapn.; elem. anal.;	99%
In tetrahydrofuran (N2); stirring (-78°C, 26 h), addn. (5% aq. Na2S2O3); washing (5% aq. Na2S2O3, 5% NH4BF4), drying (MgSO4), evapn.; elem. anal.;	43%

: 128-08-5
N-Bromosuccinimide

: 392335-71-6
2-[2,4,6-tris(bis(trimethylsilyl)methyl)phenyl]-1,2-dihydro-2-germanaphthalene

: 392335-72-7
2-bromo-2-[2,4,6-tris(bis(trimethylsilyl)methyl)phenyl]-1,2-dihydro-2-germanaphthalene

Conditions

Conditions	Yield
With BPO In benzene bromination with NBS (BPO cat.) in refluxing benzene;	99%
With catalyst: benzoyl peroxide In benzene under Ar, soln. was refluxed for 2 h; solvent was evapd., hexane added, mixt. was filtered, solvent was evapd.; elem. anal.;	99%

: 128-08-5
N-Bromosuccinimide

: 403830-45-5
N-[5-(10,20-diphenylporphirinato) zinc(II)]-N'-(octyl)pyromellitic diimide

: 403830-46-6
N-[5-(15-bromo-10,20-diphenylporphinato)zinc(II)]-N'-(octyl)pyromellitic diimide

Conditions

Conditions	Yield
In dichloromethane ligand in CH2Cl2 was added to soln. of Zn-complex in CH2Cl2 under N2, stirred at room temp. for 5 min, quenched with acetone; washed with water, dried over Na2SO4, volatiles were removed, chromd. onsilica gel with CHCl3;	99%

: 3-(dimesitylboryl)-2,2'-bithiophene

: 128-08-5
N-Bromosuccinimide

: 942612-25-1
5,5'-dibromo-3-(dimesitylboryl)-2,2'-bithiophene

Conditions

Conditions	Yield
In dichloromethane thiophene-compd. and N-bromosuccinimide in CH2Cl2;	99%

: 128-08-5
N-Bromosuccinimide

: 1051971-71-1
5,15-bis-(3-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}phenyl)porphyrin zinc

: 1051971-72-2
C46H46Br2N4O8Zn

Conditions

Conditions	Yield
With pyridine In chloroform for 0.75h;	99%

: 128-08-5
N-Bromosuccinimide

: 1062503-73-4
C57H61N5O10Zn

: 1062503-75-6
C57H60BrN5O10Zn

Conditions

Conditions	Yield
With pyridine In chloroform at 0℃;	99%

: 128-08-5
N-Bromosuccinimide

: 1008133-49-0
[Ir(1,3-di(2-pyridyl)-4,6-dimethylbenzene-N,C2,N)(6-phenyl-2,2'-bipyridine(-H))](hexafluorophosphate)

: 1008133-64-9
[Ir(1-bromo-3,5-di(2-pyridyl)-2,6-dimethylbenzene-N,C4,N)(6-(p-bromophenyl)-2,2'-bipyridine(-H))](hexafluorophosphate)

Conditions

Conditions	Yield
In acetonitrile treatment of iridium compd. with 2 equiv. of NBS in CH3CN at 20°Cfor several hs; NMR;	99%

N-Bromosuccinimide Chemical Properties

Molecular Structure :

IUPAC Name: 1-bromopyrrolidine-2,5-dione
Empirical Formula: C₄H₄BrNO₂
Molecular Weight: 177.9841
Product Categories: Nitrogen cyclic compounds; Medical Intermediates; Biochemistry; Bromination; Halogenation; N-Substituted Maleimides, Succinimides & Phthalimides; N-Substituted Succinimides; Reagents for Oligosaccharide Synthesis; Synthetic Organic Chemistry
Melting Point: 175-180 °C (dec.)(lit.)
Storage temperature: 0-6 °C
Sensitive: Moisture Sensitive
Stability: Stable. Incompatible with strong oxidizing agents, halogenated hydrocarbons.
Index of Refraction: 1.606
Surface Tension: 67.8 dyne/cm
Density: 2.042 g/cm³
Flash Point: 87.7 °C
Enthalpy of Vaporization: 45.79 kJ/mol
Boiling Point: 221.4 °C at 760 mmHg
Vapour Pressure of N-Bromosuccinimide (CAS NO.128-08-5): 0.107 mmHg at 25 °C

N-Bromosuccinimide Uses

N-Bromosuccinimide (CAS NO.128-08-5) is a chemical reagent which is used in radical substitution and electrophilic addition reactions in organic chemistry.It also can be considered a convenient source of cationic bromine.

N-Bromosuccinimide Safety Profile

Hazard Codes Corrosive C, Harmful Xn
Risk Statements 22-34-36/37/38
R22:Harmful if swallowed.
R34:Causes burns.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-36/37/39-45-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37/39:Wear suitable gloves and eye/face protection.

N-Bromosuccinimide Specification

N-Bromosuccinimide (CAS NO.128-08-5), its Synonyms are 2,5-Pyrrolidinedione, 1-bromo- ; 1-Bromo-2,5-pyrrolidinedione ; Akos bbs-00004413 ; Bromosuccinimide ; Bromosuccinimide-n;succinimide, N-bromo- ; Succinbromide ; Succinbromimide . It is white to light yellow crystalline powder.

Product Name

N-Bromosuccinimide

Synthetic route

N-Bromosuccinimide Chemical Properties

N-Bromosuccinimide Uses

N-Bromosuccinimide Safety Profile

N-Bromosuccinimide Specification

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