• Name

  PIPES

• EINECS 227-057-6
• CAS No. 5625-37-6
• Article Data3
• CAS DataBase
• Density 1.505 g/cm³
• Solubility 0.1 M NaOH: 0.25 g/mL, clear, colorless
• Melting Point >300 °C(lit.)
• Formula C₈H₁₈N₂O₆S₂
• Boiling Point
• Molecular Weight 302.373
• Flash Point
• Transport Information
• Appearance White/clear crystalline powder
• Safety 22-24/25-37/39-26
• Risk Codes 36/37/38
• Molecular Structure
• Hazard Symbols Xi
• Synonyms 1,4-Piperazinebis(ethanesulfonicacid);1,4-Piperazinebis(ethansulfonic acid);NSC 157117;1,4-Piperazinediethanesulfonicacid;Piperazine-1,4-bis(2-ethanesulfonic acid);Piperazine-N,N'-bis(2-ethanesulfonicacid);
• PSA 131.98000
• LogP 0.41700

Synthetic route

110-85-0

piperazine

15484-44-3

Na-salt of 2-chloroethane-1-sulfonic acid

5625-37-6

2,2'-piperazine-1,4-diyl-bis-ethanesulfonic acid

Conditions

Conditions	Yield
With sodium hydroxide In water for 3h; pH=9 - 9.5;	86.3%

5625-37-6

2,2'-piperazine-1,4-diyl-bis-ethanesulfonic acid

A

131543-46-9

Glyoxal

B

25127-57-5

2,2'-Ethylendiimido-diethansulfonsaeure

Conditions

Conditions	Yield
With (batho)2CuII (batho = 2,9-dimethyl-4,7-diphenyl-1,10-phenanthrolinedisulfonate); water at 25℃; for 24h; Rate constant; pH 8;

100-97-0

hexamethylenetetramine

563-63-3

silver(I) acetate

5625-37-6

2,2'-piperazine-1,4-diyl-bis-ethanesulfonic acid

2Ag(1+)*(CH2)4N2(CH2CH2SO3)2(2-)*2N4(CH2)6*14H2O=[Ag2(C8H16N2O6S2)(C6H12N4)2(H2O)2]*12H2O

Conditions

Conditions	Yield
In ammonia; water aq. NH3; acid and amine added to aq. soln. of AgCH3COO; stirred for 15 min; ppt. dissolved by dropwise addn. of aq. NH3; soln. evapd. for 2 d at room temp.;

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ammonium metavanadate

cobalt(II) chloride hexahydrate

5625-37-6

2,2'-piperazine-1,4-diyl-bis-ethanesulfonic acid

2C8H18N2O6S2*3Co(2+)*18H2O*10V(5+)*28O(2-)

Conditions

Conditions	Yield
With sodium hydroxide In methanol; water for 1.5h; pH=6;

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PIPES Chemical Properties

PIPES Safety Profile

PIPES Specification