Product Name

  • Name

    Polymyxin A

  • EINECS
  • CAS No. 1404-24-6
  • Density
  • Solubility
  • Melting Point
  • Formula
  • Boiling Point
  • Molecular Weight
  • Flash Point
  • Transport Information
  • Appearance
  • Safety Poison by intraperitoneal, subcutaneous, intravenous, and intracerebral routes. When heated to decomposition it emits acrid smoke and irritating fumes.
  • Risk Codes
  • Molecular Structure Molecular Structure of 1404-24-6 (Polymyxin A)
  • Hazard Symbols
  • Synonyms Polymixin A(7CI)
  • PSA
  • LogP

Polymyxin A Chemical Properties

Product Name: Polymyxin A
CAS NO: 1404-24-6
Classification Codes : Drug / Therapeutic Agent

Polymyxin A Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 subcutaneous 88mg/kg (88mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 3, Pg. 1542, 1978.
mouse LDLo intraperitoneal 13mg/kg (13mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Lancet. Vol. 254, Pg. 127, 1948.
mouse LDLo intravenous 6mg/kg (6mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Lancet. Vol. 254, Pg. 127, 1948.
rabbit LDLo intracrebral 600ug/kg (0.6mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Annals of the New York Academy of Sciences. Vol. 51, Pg. 952, 1949.

Polymyxin A Safety Profile

Poison by intraperitoneal, subcutaneous, intravenous, and intracerebral routes. When Polymyxin A (CAS NO.1404-24-6) is heated to decomposition ,it emits acrid smoke and irritating fumes.

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