-
Name
PROTAMINE SULFATE
- EINECS 232-726-0
- CAS No. 9009-65-8
- Density
- Solubility H2O: 10 mg/mL
- Melting Point
- Formula H2O4S
- Boiling Point
- Molecular Weight 0
- Flash Point
- Transport Information
- Appearance amorphous powder
- Safety Poison by intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects: anaphylaxis, blood pressure lowering, decreased urine volume or anuria. When heated to decomposition it emits very toxic fumes of NOx and SOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Protamine sulfates;Novoprotamine sulfate;Protamine sulfate;
- PSA 0.00000
- LogP 0.00000
Protamine sulfate Consensus Reports
Protamine sulfate Specification
The Protamine sulfate, with the CAS registry number 9009-65-8, is also known as Sulfate de protamine. It belongs to the product categories of Organic matters.What's more,Its systematic name is Protamine sulfate.It is white amorphous powder.And it is used in gene transfer, protein purification and tissue cultures. It is also used to reverse the large dose of heparin administered during the heart surgery.It is hamfull to the health ,do not breathe dust and avoid contact with skin and eyes.
The toxicity data of Protamine sulfate as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | intraperitoneal | 120mg/kg (120mg/kg) | Drugs in Japan Vol. 6, Pg. 726, 1982. | |
| guinea pig | LD50 | intravenous | 120mg/kg (120mg/kg) | Drugs in Japan Vol. 6, Pg. 726, 1982. | |
| guinea pig | LD50 | subcutaneous | 200mg/kg (200mg/kg) | Drugs in Japan Vol. 6, Pg. 726, 1982. | |
| man | LDLo | intravenous | 2174ug/kg/25M (2.174mg/kg) | VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED | Drug Intelligence and Clinical Pharmacy. Vol. 22, Pg. 211, 1988. |
| mouse | LD50 | intraperitoneal | 94mg/kg (94mg/kg) | Drugs in Japan Vol. 6, Pg. 726, 1982. | |
| mouse | LD50 | intravenous | 38mg/kg (38mg/kg) | Russian Pharmacology and Toxicology Vol. 38, Pg. 73, 1975. | |
| mouse | LD50 | subcutaneous | 200mg/kg (200mg/kg) | Drugs in Japan Vol. 6, Pg. 726, 1982. | |
| rabbit | LD50 | subcutaneous | 200mg/kg (200mg/kg) | Drugs in Japan Vol. 6, Pg. 726, 1982. | |
| rat | LD50 | intraperitoneal | 120mg/kg (120mg/kg) | Drugs in Japan Vol. 6, Pg. 726, 1982. | |
| rat | LD50 | intravenous | 75mg/kg (75mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 165, Pg. 374, 1967. |
Related Products
- Protamine sulfate
- 90097-45-3
- 90097-52-2
- 90098-04-7
- 9009-99-8
- 9010-06-4
- 9010-08-6
- 9010-10-0
- 90101-16-9
- 90101-20-5
- 90101-22-7
Hot Products
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View