Retinyl acetate supplier | CasNO.127-47-9

Name
Retinyl acetate
EINECS 204-844-2
CAS No. 127-47-9
Article Data79
CAS DataBase
Density 0.968 g/cm³
Solubility soluble in water
Melting Point 57-58 ºC
Formula C₂₂H₃₂O₂
Boiling Point 440.5 ºC at 760 mmHg
Molecular Weight 328.495
Flash Point 124.8 ºC
Transport Information
Appearance crystalline
Safety 36/37-45-37/39-26
Risk Codes 38-63-36/37/38
Molecular Structure
Hazard Symbols Xn,Xi
Synonyms Retinol,acetate, all-trans- (8CI);Myvak;Myvax;Vitamin A acetate;Vitamin A1 acetate;all-trans-Retinol acetate;all-trans-Retinyl acetate;all-trans-Vitamin Aacetate;trans-Retinol acetate;trans-Retinyl acetate;
PSA 26.30000
LogP 6.08110

Synthetic route

: 108-24-7
acetic anhydride

: 68-26-8
RETINOL

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
In hexane at 35℃; for 1h; Solvent; Temperature;	99.5%
In hexane at 35℃; for 1h;	99.5%
With triethylamine In hexane at 25℃; for 24h; Inert atmosphere; Darkness;	76%

: (2Z,4Z)-3,7-dimethyl-6-hydroxy-9-(2',6',6'-trimethylcyclohex-1'-en-1'-yl)-nona-2,4,6,8-tetraenyl acetate

: argon

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
In N-methyl-acetamide	95.8%
In N-methyl-acetamide	94.1%
In N-methyl-acetamide	93.9%

: 337913-25-4
phosphorus pentaoxide

: (2Z,4Z)-3,7-dimethyl-6-hydroxy-9-(2',6',6'-trimethylcyclohex-1'-en-1'-yl)-nona-2,4,6,8-tetraenyl acetate

: argon

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
In N-methyl-acetamide	94.9%

...Expand

: 120591-27-7
(+/-)-(E,E,E)-9-(acetyloxy)-3,7-dimethyl-1-<2,6,6-trimethyl-1-cyclohexen-1-yl>-1,5,7-nonatrien-4-one

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With iridium on carbon; hydrogen In ethanol at 50℃; under 11251.1 - 15001.5 Torr; for 3h; Reagent/catalyst; Pressure; Temperature; Solvent; Autoclave; Inert atmosphere;	93%

: 1660-94-2
Tetraethyl methylenediphosphonate

: 26586-02-7
(E)-4-acetoxy-2-methylcrotonaldehyde

: 14398-40-4
(E)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexenyl)-2-butenal

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
Stage #1: Tetraethyl methylenediphosphonate With 18-crown-6 ether; potassium tert-butylate In toluene at 30℃; for 0.5h; [1,2]-Wittig Rearrangement; Inert atmosphere; Stage #2: (E)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexenyl)-2-butenal In toluene at -5℃; for 4.5h; Stage #3: (E)-4-acetoxy-2-methylcrotonaldehyde In toluene at -40℃; for 1h; Reagent/catalyst; Solvent; Temperature;	93%

...Expand

: 14918-80-0
3-methyl-4-oxobut-2-enyl acetate

: 1062-12-0
β-Jonylidenaethyl-triphenyl-phosphonium-chlorid

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With 1-butyl-3-methylimidazolium imidazolide; sodium hydroxide In hexane; water at 43℃; for 2h; Reagent/catalyst; Temperature; Solvent; Autoclave; Inert atmosphere;	92.92%

: 26586-02-7
(E)-4-acetoxy-2-methylcrotonaldehyde

: 53282-28-3
[(2E,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dienyl]triphenylphosphonium chloride

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With potassium hydroxide In isopropyl alcohol at 0 - 10℃; for 2h; Wittig Olefination; Inert atmosphere;	92.8%
With potassium hydroxide In N,N-dimethyl-formamide; isopropyl alcohol at 0 - 10℃; for 2h; Inert atmosphere;	91.9%

: 26586-02-7
(E)-4-acetoxy-2-methylcrotonaldehyde

: 62285-98-7
5-(2,6,6-trimethylcyclohexenyl)-3-methyl-2,4-pentadienyltriphenylphosphonium bromide

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With sodium ethanolate In N,N-dimethyl-formamide at -5 - 0℃; for 2h; Solvent; Temperature; Reagent/catalyst; Wittig Olefination; Inert atmosphere;	91%
With sodium ethanolate In N,N-dimethyl-formamide at -5 - 5℃; for 2h; Time; Inert atmosphere;	90.7%

: 475558-35-1
1-acetoxy-5.9-dibensenesulfonyl-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,6-nonadiene

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With sodium hydroxide In ethanol for 15h; Heating;	82%

: 26586-02-7
(E)-4-acetoxy-2-methylcrotonaldehyde

: [(2E,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dienyl]triphenylphosphonium hydrogensulfate

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With ammonia In water at 50℃; for 0.5h; Product distribution / selectivity; Wittig Reaction;	77%

: 127-47-9, 22586-94-3, 29443-87-6, 29444-27-7, 29584-22-3, 34356-31-5, 63568-38-7, 98462-63-6, 137121-50-7, 137121-51-8, 137121-55-2
(9Ξ,11Ξ,13Ξ)-O-acetyl-retinol

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With erythrosine B In methanol; n-heptane at 15℃; for 4h; Irradiation;	76.8%

: 7,8-dihydroretinyl acetate

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With triethanolamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone In ethyl acetate at 20 - 77℃; for 1h; Temperature; Solvent;	75%

: 75-36-5
acetyl chloride

: 388075-89-6
1,3,3-trimethyl-2-[(2E,4E,6E)-3,7-dimethyl-2,4,6,8-nonatetraenyl]cyclohexene

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
Stage #1: 1,3,3-trimethyl-2-[(2E,4E,6E)-3,7-dimethyl-2,4,6,8-nonatetraenyl]cyclohexene With NMPA; lithium diisopropyl amide In tetrahydrofuran; hexane Stage #2: With sodium hydroxide; fluorodimethoxyborane diethyl etherate In tetrahydrofuran at 25℃; for 2h; Stage #3: acetyl chloride With pyridine In dichloromethane at 25℃; for 3h; Further stages.;	41%

: 388075-83-0
(2E,6E,8E)-4-bromo-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,6,8-nonatrienyl acetate

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With 2,6-dichloro-benzonitrile In hexane at 25℃; for 6h;	31%

: 26586-02-7
(E)-4-acetoxy-2-methylcrotonaldehyde

: 128759-88-6
3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienylphosphonic acid,diethyl ester

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With dimethyl sulfoxide In tetrahydrofuran; hexane; water	7.1%
In di-isopropyl ether; water	7.9%
In N-methyl-acetamide; water; toluene	7%

: 3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienylphosphonic acid,dimethyl ester

: methyl ethyl 3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienylphosphonate

: 26586-02-7
(E)-4-acetoxy-2-methylcrotonaldehyde

: 128759-88-6
3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienylphosphonic acid,diethyl ester

: 865-48-5
sodium t-butanolate

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
In N-methyl-acetamide; toluene	6.9%

...Expand

: 110-86-1
pyridine

: 68-26-8
RETINOL

: 75-36-5
acetyl chloride

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With 1,2-dichloro-ethane
With diethyl ether

...Expand

: 14918-80-0
3-methyl-4-oxobut-2-enyl acetate

: 55497-46-6
1,5,5-trimethyl-6-(3-methyl-penta-2,4-dienylidene)-cyclohexene

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With triphenylphosphine hydrochloride

: 108-24-7
acetic anhydride

: 105096-76-2
1-hydroxy-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-9-phenylsulfonyl-2,6,8-nonatriene

A: 127-47-9
Retinol acetate

B: 29584-22-3
9-cis-Vitamin-A-acetat

C: 29443-87-6
11-cis-Vitamin-A-acetat

D: 34356-31-5
(7E,9E,11E,13Z)-retinyl acetate

Conditions

Conditions	Yield
With potassium methanolate 1.) cyclohexane, 38 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

: 108-24-7
acetic anhydride

: 103905-08-4
1-acetoxy-6-chloro-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-9-phenylsulfonyl-2,7-nonadiene

A: 127-47-9
Retinol acetate

B: 68-26-8, 2052-63-3, 6018-74-2, 17706-49-9, 22737-96-8, 29444-25-5, 34218-73-0, 39815-04-8, 69686-68-6, 69686-69-7, 74743-94-5, 84415-27-0, 84415-28-1, 85354-09-2, 85354-10-5, 93380-02-0, 98462-62-5, 137121-52-9, 22737-97-9
9-cis-retinol

C: 34356-31-5
(7E,9E,11E,13Z)-retinyl acetate

Conditions

Conditions	Yield
With potassium methanolate; triethylamine 1.) cyclohexane, 38 deg C, 2 h, 2.) hexane; Yield given. Multistep reaction;

...Expand

: 108-24-7
acetic anhydride

: 103905-09-5
1-acetoxy-6-bromo-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-9-phenylsulfonyl-2,7-nonadiene

A: 127-47-9
Retinol acetate

B: 29584-22-3
9-cis-Vitamin-A-acetat

C: 29443-87-6
11-cis-Vitamin-A-acetat

D: 34356-31-5
(7E,9E,11E,13Z)-retinyl acetate

Conditions

Conditions	Yield
With potassium methanolate 1.) cyclohexane, 38 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

: 3230-76-0, 34255-07-7, 60102-36-5, 62653-03-6
10,15-dihydroxy-9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohex-6-enyl)-8,11,13-nonatriene

A: 127-47-9
Retinol acetate

B: 34356-31-5
(7E,9E,11E,13Z)-retinyl acetate

C: 139697-18-0
(3E,5E,7E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-3,5,7-triene-1,2-diol

D: 59677-18-8, 59728-52-8, 139758-19-3
Acetic acid (2Z,4Z,6E)-8-hydroxy-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6-trienyl ester

E: 62417-07-6, 139890-93-0
Acetic acid (3E,5Z,7Z)-2-hydroxy-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-3,5,7-trienyl ester

F: 62417-07-6, 139890-93-0
Acetic acid (3E,5E,7E)-2-hydroxy-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-3,5,7-trienyl ester

Conditions

Conditions	Yield
Product distribution; Mechanism; multistep reaction; dehydrochlorination;

...Expand

: 139697-15-7, 139758-18-2
Acetic acid (2Z,4Z,6E)-8-chloro-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6-trienyl ester

A: 127-47-9
Retinol acetate

B: 139697-18-0
(3E,5E,7E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-3,5,7-triene-1,2-diol

C: 59677-18-8, 59728-52-8, 139758-19-3
Acetic acid (2Z,4Z,6E)-8-hydroxy-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6-trienyl ester

D: 62417-07-6, 139890-93-0
Acetic acid (3E,5E,7E)-2-hydroxy-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-3,5,7-trienyl ester

E: 139697-16-8, 139890-92-9
Acetic acid (3E,5Z,7Z)-2-chloro-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-3,5,7-trienyl ester

F: 139697-16-8, 139890-92-9
Acetic acid (3E,5E,7E)-2-chloro-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-3,5,7-trienyl ester

Conditions

Conditions	Yield
With hydrogenchloride at 35℃; for 3h; Rate constant; other 8- and 14-chloroacetates;

...Expand

: 105096-76-2
1-hydroxy-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-9-phenylsulfonyl-2,6,8-nonatriene

A: 127-47-9
Retinol acetate

B: 29584-22-3
9-cis-Vitamin-A-acetat

C: 29443-87-6
11-cis-Vitamin-A-acetat

D: 34356-31-5
(7E,9E,11E,13Z)-retinyl acetate

Conditions

Conditions	Yield
With potassium methanolate In cyclohexane at 38℃; for 2h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

(+-)-9-acetoxy-3.7-dimethyl-1-<2.2.6-trimethyl-cyclohexen-(6)-yl>-nonatrien-(2ξ.5c.7ξ)-ol-(4): (+-)-9-acetoxy-3.7-dimethyl-1-<2.2.6-trimethyl-cyclohexen-(6)-yl>-nonatrien-(2ξ.5c.7ξ)-ol-(4)

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With iodine; Petroleum ether; Tocopherol bei Siedetemperatur;
With pyridine; toluene; trichlorophosphate at 90 - 95℃; Durchleiten von Stickstoff;

3,7-dimethyl-9-<2,6,6-trimethyl-cyclohex-1-enyl>-nona-2c,4c,7ξ-triene-1,6-diol: 3,7-dimethyl-9-<2,6,6-trimethyl-cyclohex-1-enyl>-nona-2c,4c,7ξ-triene-1,6-diol

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
Acetylierung und aufeinanderfolgendes Behandeln mit HCl und mit NaHCO3 ;
Acetylierung und aufeinanderfolgendes Behandeln mit HCl und mit NaHCO3 ;

: 14918-80-0
3-methyl-4-oxobut-2-enyl acetate

3-methyl-5t-<2,6,6-trimethyl-cyclohex-1-enyl>-penta-2t,4-dien-1-ol: 3-methyl-5t-<2,6,6-trimethyl-cyclohex-1-enyl>-penta-2t,4-dien-1-ol

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
With triphenylphosphine hydrochloride

: 110-86-1
pyridine

: 62417-05-4, 95404-32-3
(+/-)-9-acetoxy-3.7-dimethyl-1-(2.2.6-trimethyl-cyclohexen-(6)-yl)-nonatrien-(2ξ.5c.7c)-ol-(4)

: 108-88-3
toluene

: 10025-87-3, 12599-09-6, 63736-95-8
trichlorophosphate

: 127-47-9
Retinol acetate

Conditions

Conditions	Yield
at 90 - 95℃;

...Expand

: 112-39-0
hexadecanoic acid methyl ester

: 127-47-9
Retinol acetate

: 79-81-2
retinyl palmitate

Conditions

Conditions	Yield
With sodium hydroxide In methanol at 55℃; under 11.2511 - 16.5017 Torr; for 3h; Concentration; Pressure; Large scale;	96%

: 127-47-9
Retinol acetate

: 7235-40-7
beta-carotene

Conditions

Conditions	Yield
Stage #1: Retinol acetate With sulfuric acid; triphenylphosphine In methanol at 0 - 5℃; for 10.5h; Stage #2: With palladium diacetate; β‐cyclodextrin In ethanol; dichloromethane; water under 16501.7 Torr; for 8h; Reagent/catalyst; Solvent; Pressure; Temperature; Autoclave;	90.6%
Stage #1: Retinol acetate With aniline In ethanol Stage #2: With hydrogenchloride; triphenylphosphine In ethanol; water at 10 - 25℃; for 26h; Reagent/catalyst; Solvent; Further stages;	58.75%

: 127-47-9
Retinol acetate

: 68-26-8
RETINOL

Conditions

Conditions	Yield
With methyllithium In tetrahydrofuran at -15℃; for 0.75h; Inert atmosphere;	83%
With water
With methyllithium In diethyl ether at -15℃; for 2h;	600 mg

: 127-47-9
Retinol acetate

: 29584-22-3
9-cis-Vitamin-A-acetat

Conditions

Conditions	Yield
In acetonitrile at 25℃; for 24h; UV-irradiation;	80%
With dichloro bis(acetonitrile) palladium(II); triethylamine In hexane at 65℃; for 20h; Catalytic behavior; Reagent/catalyst; Solvent; Inert atmosphere;	n/a

: 127-47-9
Retinol acetate

: 57-10-3
1-hexadecylcarboxylic acid

A: 79-81-2
retinyl palmitate

B: 68-26-8
RETINOL

Conditions

Conditions	Yield
With Novozyme 435 (from Candida antarctica immobilized on acrylic resin); Amberlyst A-21 In toluene at 20℃; for 15h; Product distribution / selectivity; Enzymatic reaction;	A 78% B n/a

...Expand

: 127-47-9
Retinol acetate

: 1077-28-7, 62-46-4
Thioctic acid

A: retinyl lipoate

B: 68-26-8
RETINOL

Conditions

Conditions	Yield
With Novozyme 435 (from Candida antarctica immobilized on acrylic resin); Amberlyst A-21 In toluene at 20℃; for 21h; Product distribution / selectivity; Enzymatic reaction; Sonication;	A 71% B n/a

...Expand

: 60-33-3
linoleic acid

: 127-47-9
Retinol acetate

A: retinyl linoleate

B: 68-26-8
RETINOL

Conditions

Conditions	Yield
With Novozyme 435 (from Candida antarctica immobilized on acrylic resin); Amberlyst A-21 In toluene at 20℃; for 2 - 50h; Product distribution / selectivity; Enzymatic reaction;	A 71% B n/a
With Novozyme 435 (from Candida antarctica immobilized on acrylic resin) In toluene at 20 - 50℃; for 1 - 2h; Product distribution / selectivity; Enzymatic reaction;
With Lipozyme TI IM; Amberlyst A-21 In toluene at 20℃; for 45h; Product distribution / selectivity; Enzymatic reaction;

...Expand

: 112-80-1
cis-Octadecenoic acid

: 127-47-9
Retinol acetate

A: 631-88-9
retinyl stearate

B: 68-26-8
RETINOL

Conditions

Conditions	Yield
With Novozyme 435 (from Candida antarctica immobilized on acrylic resin); Amberlyst A-21 In toluene at 20℃; for 15h; Product distribution / selectivity; Enzymatic reaction;	A 69% B n/a

...Expand

: 127-47-9
Retinol acetate

A: 166584-42-5
Acetic acid (4E,6E,8E)-(2S,3S)-2,3-dihydroxy-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-4,6,8-trienyl ester

B: Acetic acid (3E,5E,7E)-(1S,2S)-2-hydroxy-1-hydroxymethyl-2,6-dimethyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trienyl ester

Conditions

Conditions	Yield
With potassium osmate(VI); Hydroquinone 1,4-phthalazinediyl diether; methanesulfonamide; potassium carbonate; potassium hexacyanoferrate(III) In water; tert-butyl alcohol at 0℃; for 4h; Yields of byproduct given;	A 63% B n/a

: 127-47-9
Retinol acetate

A: 113563-63-6
Hexahydrovitamin A acetate

B: 113563-62-5
9,13-Dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-8,13-nonadien-15-ol acetate

Conditions

Conditions	Yield
With hydrogen; nickel In methanol for 0.5h; Ambient temperature; Yields of byproduct given;	A 62.5% B n/a
With hydrogen; nickel In methanol for 0.5h; Ambient temperature; Yield given. Yields of byproduct given;

: 1968-40-7
ethyl 4-pentenoate

: 127-47-9
Retinol acetate

A: 43219-55-2
(1E,3E)-3-methyl-1-[2,6,6-trimethylcyclohex-1-enyl]hexa-1,3,5-triene

B: ethyl (11Z)-13-nor-13,14-dihydroretinoate

C: 1332483-21-2
ethyl (11E)-13-nor-13,14-dihydroretinoate

Conditions

Conditions	Yield
With Hoveyda-Grubbs catalyst second generation In toluene at 20℃; for 96h; Inert atmosphere; optical yield given as %de; diastereoselective reaction;	A 33% B n/a C n/a

...Expand

: 127-47-9
Retinol acetate

: 1332483-19-8
(2E,4EZ)-N-(4-hexyloxyphenyl)-3-methylhexa-2,4-dienamide

: 1332483-22-3
N-(4-hexyloxyphenyl)retinamide

Conditions

Conditions	Yield
With Hoveyda-Grubbs catalyst second generation In dichloromethane; toluene at 20℃; for 96h; Inert atmosphere; optical yield given as %de; diastereoselective reaction;	26%

: 127-47-9
Retinol acetate

: 43219-27-8
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-amine

Conditions

Conditions	Yield
Stage #1: Retinol acetate With sodium hydroxide Stage #2: With manganese(IV) oxide In hexane Further stages;	23.5%

: 127-47-9
Retinol acetate

: N-(4-hydroxyphenyl)sorbamide

: 1332483-33-6
N-(4-hydroxyphenyl)-13-apo-β-caroten-13-amide

Conditions

Conditions	Yield
With Hoveyda-Grubbs catalyst second generation In toluene at 20℃; Inert atmosphere; optical yield given as %de; diastereoselective reaction;	13%

Retinyl acetate Chemical Properties

IUPAC Name: [(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] acetate
Molecular Formula: C₂₂H₃₂O₂
Molecular Weight: 328.49 g/mol
SMILES: O=C(OCC=C(C=CC=C(C=C/C1=C(/CCCC1(C)C)C)C)C)C Copy
InChI: InChI=1/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3
EINECS: 204-844-2
Classification Code: Adjuvants, immunologic; Anticarcinogenic agents; Antineoplastic Agents; Immunologic Factors; Mutation data; Protective Agents; Reproductive Effect; Tumor data
Melting Point: 57-58 °C
storage temperature: 2-8 °C
solubility: absolute ethanol: 25 mg/mL
Water Solubility: soluble
Index of Refraction: 1.531
Molar Refractivity: 105 cm³
Molar Volume: 339 cm³
Surface Tension: 35.3 dyne/cm
Density: 0.968 g/cm³
Flash Point: 124.8 °C
Enthalpy of Vaporization: 69.76 kJ/mol
Boiling Point: 440.5 °C at 760 mmHg
Vapour Pressure of Retinyl acetate (CAS NO.127-47-9): 5.86E-08 mmHg at 25 °C

Retinyl acetate Uses

Retinyl acetate (CAS NO.127-47-9) is used for vitamin A deficiency.

Retinyl acetate Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	432mg/kg (432mg/kg)		United States Patent Document. Vol. #3878202,
mouse	LD50	oral	4100mg/kg (4100mg/kg)		Journal of the American Academy of Dermatology. Vol. 6, Pg. 652, 1982.

Retinyl acetate Safety Profile

Hazard Codes: Harmful Xn, Irritant Xi
Risk Statements: 38-63-36/37/38
R38:Irritating to skin.
R63:Possible risk of harm to the unborn child.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 36/37-45-37/39-26
S36/37:Wear suitable protective clothing and gloves.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37/39:Wear suitable gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 2
RTECS of Retinyl acetate (CAS NO.127-47-9): VH6825000

Retinyl acetate Specification

Retinyl acetate (CAS NO.127-47-9), its Synonyms are Acetic acid, retinyl ester ; Vitamin A acetate ; Retinol, acetate, all-trans- ; Vitamin A alcohol acetate ; Vitamin A ester ; Vitamin A1 acetate ; Retinol, acetate, all-trans- (8CI) ; all-trans-Retinylacetate ; all-trans-Vitamin A acetate . It is crystalline.

Product Name

Retinyl acetate

Synthetic route

Retinyl acetate Chemical Properties

Retinyl acetate Uses

Retinyl acetate Toxicity Data With Reference

Retinyl acetate Safety Profile

Retinyl acetate Specification

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