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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Food Grade Vitamin A palmitate 79-81-2 HACCP Manufacturer

Cas:79-81-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Hangzhou Think Chemical Co. Ltd

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exp

High quality Vitamin A Palmitate 1.7MIU oil supplier

Cas:79-81-2

Min.Order:20 Kilogram

Negotiable

Type:Other

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Vitamin A palmitate Cas 79-81-2 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Yellow or brown yellow oily liquid Storage:Store in 2-8℃ Package:2

High quality 1.7Miu oil Vitamin A palmitate Cas 79-81-2 with favorable price

Cas:79-81-2

Min.Order:1 Kilogram

FOB Price: $190.0 / 205.0

Type:Trading Company

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Kono Chem Co.,Ltd

CAS No.: 79-81-2 Other Names: Retinol palmitate MF: C36H60O2 EINECS No.: 201-228-5 Place of Origin: Henan, China (Mainland) Type: Vitamins, Amino Acids and C

Vitamin A Palmitate Retinol Palmitate Powder/Oil

Cas:79-81-2

Min.Order:1 Kilogram

FOB Price: $95.0 / 110.0

Type:Other

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Retinol palmitate Manufacturer/High quality/Best price/In stock

Cas:79-81-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance Yellow or brown yellow oily liquid Complies Identification

Top purity Vitamin A Palmitate with high quality and best price cas:79-81-2

Cas:79-81-2

Min.Order:1 Kilogram

FOB Price: $300.0 / 400.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Retinol Palmitate supplier in China

Cas:79-81-2

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Hot sale Vitamin A Palmitate 99% min CAS NO.79-81-2

Cas:79-81-2

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

vitamin A palmitate manufacturer/supplier

Cas:79-81-2

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Hefei TNJ chemical industry co.,ltd

1, Full experience of large numbers containers loading in main Chinese seaports 2, Packing with pallet as buyer's special request 3, Best service after shipment with e-mail 4, Cargoes together with container sales service available

High Quality CAS 79-81-2 Vitamin A Palmitate Retinol palmitate

Cas:79-81-2

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Retinyl palmitate

Cas:79-81-2

Min.Order:1

Negotiable

Type:Other

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Vitamin A Palmitate

Cas:79-81-2

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Vitamin A palmitate

Cas:79-81-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Retinol palmitate Basic information Product Name: Retinol palmitate Synonyms: AROVIT;ALL TRANS-RETINOL PALMITATE;RETINOL PALMITATE;RETINOL PALMITATE ALL TRANS;RETINOL PALMITATE ALL TRANS

Retinol palmitate

Cas:79-81-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

Vitamin A palmitate 79-81-2

Cas:79-81-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 79-81-2 with competitive price

Cas:79-81-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

Retinol palmitate CAS79-81-2

Cas:79-81-2

Min.Order:1 Kilogram

FOB Price: $7.0 / 9.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: High quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Food Grade Vitamin A palmitate CAS 79-81-2 For Nutritional Supplement In Large Stock

Cas:79-81-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Retinol palmitate/ LIDE PHARMA- Factory supply / Best price

Cas:79-81-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

Prodcut name Vitamin A Palmitate CAS No. 79-81-2 Appearance Light yellow liquid Molecular Formula C36H60O2 Molecular Weight 524.87 Appearance:light yellow liquid Storage:Preserve in we

Vitamin A Palmitate

Cas:79-81-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

99% Retinol Palmitate CAS:79-81-2

Cas:79-81-2

Min.Order:10 Gram

Negotiable

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:Light Yellow to Yellow Oil Storage:Room temperature Package:25kg/Barrel Application:Used as medicines, food additives and feed additives, etc. Transportation:Express/Sea/Air Port:Any port in china

High Quality Retinol Palmitate Vitamin A Palmitate 1.7MIU Oil

Cas:79-81-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Retinol palmitate 79-81-2

Cas:79-81-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

High Quality API 99% purity Vitamin A palmitate powder pure Retinol Palmitate raw Powder

Cas:79-81-2

Min.Order:10 Gram

FOB Price: $0.6

Type:Trading Company

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HANWAYS CHEMPHARM CO.,LIMITED

Wuhan hanweishi Pharmchem Co., Ltd(Hanways chempharm) is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The leading products range are APIs, Hormones, Peptides

Vitamin A palmitate CAS 79-81-2

Cas:79-81-2

Min.Order:100 Kilogram

FOB Price: $1.0 / 5.0

Type:Trading Company

inquiry

Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:oil or powder Storage:Refer to COA / MSDS Packa

Retinol palmitate 99% Vitamin A Palmitate 99% powder oil

Cas:79-81-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

GMP/DMF/COS/CEP/FDA/FAMI-QS/HALAL Appearance:yellow or brown yellow oily liquid Storage:2-8°C Package:as client requirement Application:antihypertensive Transportation:Express, Air ,Sea Port:Any port of China

Vitamin A Palmitate 1.7Miu Oil Feed Grade

Cas:79-81-2

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At presen

Vitamin A palmitate C36H60O2

Cas:79-81-2

Min.Order:25 Milliliter

FOB Price: $45.0 / 50.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Vitamin A palmitate CAS: 79-81-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interme

Vitamin A palmitate CAS: 79-81-2

Cas:79-81-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Retinol palmitate

Cas:79-81-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

RETINOL
68-26-8

RETINOL

n-hexadecanoyl chloride
112-67-4

n-hexadecanoyl chloride

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
In toluene at 35℃; for 1h;99%
With pyridine In 1,2-dichloro-ethane
palmitic anhydride
623-65-4

palmitic anhydride

RETINOL
68-26-8

RETINOL

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
With aluminum oxide In Petroleum ether at 40℃; for 2h; Solvent;97.62%
hexadecanoic acid methyl ester
112-39-0

hexadecanoic acid methyl ester

Retinol acetate
127-47-9

Retinol acetate

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
With sodium hydroxide In methanol at 55℃; under 11.2511 - 16.5017 Torr; for 3h; Concentration; Pressure; Large scale;96%
hexadecanoic acid methyl ester
112-39-0

hexadecanoic acid methyl ester

RETINOL
68-26-8

RETINOL

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
at 60℃; under 0.750075 Torr; for 3h; Temperature; Large scale;94%
4-palmitoyloxy-2-methyl-2-buten-1-al

4-palmitoyloxy-2-methyl-2-buten-1-al

5-(2,6,6-trimethylcyclohexenyl)-3-methyl-2,4-pentadienyltriphenylphosphonium bromide
62285-98-7

5-(2,6,6-trimethylcyclohexenyl)-3-methyl-2,4-pentadienyltriphenylphosphonium bromide

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
With sodium ethanolate In N,N-dimethyl-formamide at -5 - 5℃; for 3h; Wittig Olefination; Inert atmosphere;91.3%
4-palmitoyloxy-2-methyl-2-buten-1-al

4-palmitoyloxy-2-methyl-2-buten-1-al

[(2E,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dienyl]triphenylphosphonium chloride
53282-28-3

[(2E,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dienyl]triphenylphosphonium chloride

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
With potassium hydroxide In isopropyl alcohol at 5 - 20℃; for 2h; Wittig Olefination; Inert atmosphere;90.8%
diethyl 3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienylphosphonate
186194-14-9

diethyl 3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienylphosphonate

2-methyl-4-palmitoyloxy-2-butenal

2-methyl-4-palmitoyloxy-2-butenal

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Stage #1: diethyl 3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienylphosphonate With sodium t-butanolate In toluene at 0℃; for 0.5h; Inert atmosphere;
Stage #2: 2-methyl-4-palmitoyloxy-2-butenal In toluene for 3h; Reagent/catalyst; Solvent; Inert atmosphere;
89%
Retinol acetate
127-47-9

Retinol acetate

1-hexadecylcarboxylic acid
57-10-3

1-hexadecylcarboxylic acid

A

retinyl palmitate
79-81-2

retinyl palmitate

B

RETINOL
68-26-8

RETINOL

Conditions
ConditionsYield
With Novozyme 435 (from Candida antarctica immobilized on acrylic resin); Amberlyst A-21 In toluene at 20℃; for 15h; Product distribution / selectivity; Enzymatic reaction;A 78%
B n/a
pyridine
110-86-1

pyridine

RETINOL
68-26-8

RETINOL

n-hexadecanoyl chloride
112-67-4

n-hexadecanoyl chloride

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
With 1,2-dichloro-ethane
pyridine
110-86-1

pyridine

(+/-)-9-palmitoyloxy-3.7-dimethyl-1-(2.2.6-trimethyl-cyclohexen-(6)-yl)-nonatrien-(2ξ.5c.7c)-ol-(4)

(+/-)-9-palmitoyloxy-3.7-dimethyl-1-(2.2.6-trimethyl-cyclohexen-(6)-yl)-nonatrien-(2ξ.5c.7c)-ol-(4)

toluene
108-88-3

toluene

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
at 90 - 95℃;
(+/-)-9-palmitoyloxy-3.7-dimethyl-1-(2.2.6-trimethyl-cyclohexen-(6)-yl)-nonatrien-(2ξ.5c.7c)-ol-(4)

(+/-)-9-palmitoyloxy-3.7-dimethyl-1-(2.2.6-trimethyl-cyclohexen-(6)-yl)-nonatrien-(2ξ.5c.7c)-ol-(4)

iodine
7553-56-2

iodine

petroleum ether

petroleum ether

retinyl palmitate
79-81-2

retinyl palmitate

4-palmitoyloxy-2-methyl-2-buten-1-al

4-palmitoyloxy-2-methyl-2-buten-1-al

3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,4-pentadienylphosphonic acid,diethyl ester
128759-92-2

3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,4-pentadienylphosphonic acid,diethyl ester

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
With sodium t-butanolate In water; N,N-dimethyl-formamide; toluene
Retinol acetate
127-47-9

Retinol acetate

1-hexadecylcarboxylic acid
57-10-3

1-hexadecylcarboxylic acid

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
With Candida sp.99-125 lipase immobilized on SBA-15 In hexane at 30℃; for 6h; Enzymatic reaction;75.2 %Chromat.
With novozyme 435 In toluene at 20℃; for 20h; Schlenk technique; Inert atmosphere; Enzymatic reaction;
farnesyl alcohol
82010-11-5

farnesyl alcohol

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: TEMPOL; copper(l) chloride / N,N-dimethyl-formamide / 2 h / 30 °C
2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 0.5 h / 50 °C
3.1: sulfuric acid / 1,2-dichloro-ethane / 0 - 5 °C
4.1: triphenylphosphine / methanol / 1 h / 45 °C
4.2: 1 h / 45 °C
5.1: toluene / 1 h / 35 °C
View Scheme
(2E)-farnesal
80442-43-9

(2E)-farnesal

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 0.5 h / 50 °C
2.1: sulfuric acid / 1,2-dichloro-ethane / 0 - 5 °C
3.1: triphenylphosphine / methanol / 1 h / 45 °C
3.2: 1 h / 45 °C
4.1: toluene / 1 h / 35 °C
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sulfuric acid / 1,2-dichloro-ethane / 0 - 5 °C
2.1: triphenylphosphine / methanol / 1 h / 45 °C
2.2: 1 h / 45 °C
3.1: toluene / 1 h / 35 °C
View Scheme
(2E,4E)-3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienal
3917-41-7

(2E,4E)-3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienal

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triphenylphosphine / methanol / 1 h / 45 °C
1.2: 1 h / 45 °C
2.1: toluene / 1 h / 35 °C
View Scheme
2-(bromomethyl)-1,3,3-trimethylcyclohex-1-ene
59633-88-4

2-(bromomethyl)-1,3,3-trimethylcyclohex-1-ene

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: hexane / 4 h / 50 - 55 °C / Inert atmosphere
2.1: potassium hydroxide / isopropyl alcohol / 1 h / -5 - 5 °C / Inert atmosphere
3.1: potassium hydroxide / water; dichloromethane / 3 h / 10 - 15 °C
3.2: 3 h / 20 - 25 °C
4.1: isopropyl alcohol / 5 h / 55 - 60 °C / Inert atmosphere
5.1: potassium hydroxide / isopropyl alcohol / 2 h / 5 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 5 steps
1.1: hexane / 4 h / 50 - 55 °C / Inert atmosphere
2.1: potassium hydroxide / isopropyl alcohol / 1 h / -5 - 5 °C / Inert atmosphere
3.1: sodium hydroxide / water; dichloromethane / 3 h / 15 - 20 °C
3.2: 3 h / 20 - 25 °C
4.1: acetonitrile / 5 h / 50 - 55 °C / Inert atmosphere
5.1: sodium ethanolate / N,N-dimethyl-formamide / 3 h / -5 - 5 °C / Inert atmosphere
View Scheme
C28H32P(1+)*Cl(1-)

C28H32P(1+)*Cl(1-)

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium ethanolate / N,N-dimethyl-formamide / 5 h / -5 - 10 °C / Inert atmosphere
2.1: potassium hydroxide / water; dichloromethane / 3 h / 10 - 15 °C
2.2: 3 h / 20 - 25 °C
3.1: isopropyl alcohol / 5 h / 55 - 60 °C / Inert atmosphere
4.1: potassium hydroxide / isopropyl alcohol / 2 h / 5 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 4 steps
1.1: sodium ethanolate / N,N-dimethyl-formamide / 5 h / -5 - 10 °C / Inert atmosphere
2.1: sodium hydroxide / water; dichloromethane / 3 h / 15 - 20 °C
2.2: 3 h / 20 - 25 °C
3.1: acetonitrile / 5 h / 50 - 55 °C / Inert atmosphere
4.1: sodium ethanolate / N,N-dimethyl-formamide / 3 h / -5 - 5 °C / Inert atmosphere
View Scheme
diethyl [(2,2,6-trimethylcyclohexyl)methyl]phosphonate

diethyl [(2,2,6-trimethylcyclohexyl)methyl]phosphonate

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium methylate / N,N-dimethyl-formamide / 1 h / 0 - 15 °C / Inert atmosphere
2.1: potassium hydroxide / water; dichloromethane / 3 h / 10 - 15 °C
2.2: 3 h / 20 - 25 °C
3.1: isopropyl alcohol / 5 h / 55 - 60 °C / Inert atmosphere
4.1: potassium hydroxide / isopropyl alcohol / 2 h / 5 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 4 steps
1.1: sodium methylate / N,N-dimethyl-formamide / 1 h / 0 - 15 °C / Inert atmosphere
2.1: sodium hydroxide / water; dichloromethane / 3 h / 15 - 20 °C
2.2: 3 h / 20 - 25 °C
3.1: acetonitrile / 5 h / 50 - 55 °C / Inert atmosphere
4.1: sodium ethanolate / N,N-dimethyl-formamide / 3 h / -5 - 5 °C / Inert atmosphere
View Scheme
triphenyl((2,6,6-trimethylcyclohex-1-enyl)methyl)phosphonium bromide
56013-01-5

triphenyl((2,6,6-trimethylcyclohex-1-enyl)methyl)phosphonium bromide

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: potassium hydroxide / isopropyl alcohol / 1 h / -5 - 5 °C / Inert atmosphere
2.1: potassium hydroxide / water; dichloromethane / 3 h / 10 - 15 °C
2.2: 3 h / 20 - 25 °C
3.1: isopropyl alcohol / 5 h / 55 - 60 °C / Inert atmosphere
4.1: potassium hydroxide / isopropyl alcohol / 2 h / 5 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 4 steps
1.1: potassium hydroxide / isopropyl alcohol / 1 h / -5 - 5 °C / Inert atmosphere
2.1: sodium hydroxide / water; dichloromethane / 3 h / 15 - 20 °C
2.2: 3 h / 20 - 25 °C
3.1: acetonitrile / 5 h / 50 - 55 °C / Inert atmosphere
4.1: sodium ethanolate / N,N-dimethyl-formamide / 3 h / -5 - 5 °C / Inert atmosphere
View Scheme
3-methyl-5-acetoxy-1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3-pentadiene
3917-38-2

3-methyl-5-acetoxy-1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3-pentadiene

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: potassium hydroxide / water; dichloromethane / 3 h / 10 - 15 °C
1.2: 3 h / 20 - 25 °C
2.1: isopropyl alcohol / 5 h / 55 - 60 °C / Inert atmosphere
3.1: potassium hydroxide / isopropyl alcohol / 2 h / 5 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1.1: sodium hydroxide / water; dichloromethane / 3 h / 15 - 20 °C
1.2: 3 h / 20 - 25 °C
2.1: acetonitrile / 5 h / 50 - 55 °C / Inert atmosphere
3.1: sodium ethanolate / N,N-dimethyl-formamide / 3 h / -5 - 5 °C / Inert atmosphere
View Scheme
5-(2,6,6-trimethyl-cyclohex-1-enyl)-3-methyl-1-chloro-penta-2,4-diene
55732-70-2

5-(2,6,6-trimethyl-cyclohex-1-enyl)-3-methyl-1-chloro-penta-2,4-diene

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: isopropyl alcohol / 5 h / 55 - 60 °C / Inert atmosphere
2: potassium hydroxide / isopropyl alcohol / 2 h / 5 - 20 °C / Inert atmosphere
View Scheme
3-methyl-5-bromo-1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3-pentadiene
38987-92-7

3-methyl-5-bromo-1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3-pentadiene

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetonitrile / 5 h / 50 - 55 °C / Inert atmosphere
2: sodium ethanolate / N,N-dimethyl-formamide / 3 h / -5 - 5 °C / Inert atmosphere
View Scheme
3,7-dimethylocta-1,6-dien-3-ol
78-70-6

3,7-dimethylocta-1,6-dien-3-ol

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: hydrogen bromide; sodium hydroxide / water; dichloromethane / 2 h / 30 - 35 °C / Inert atmosphere
1.2: 2 h / 35 - 40 °C
2.1: hexane / 4 h / 50 - 55 °C / Inert atmosphere
3.1: potassium hydroxide / isopropyl alcohol / 1 h / -5 - 5 °C / Inert atmosphere
4.1: sodium hydroxide / water; dichloromethane / 3 h / 15 - 20 °C
4.2: 3 h / 20 - 25 °C
5.1: acetonitrile / 5 h / 50 - 55 °C / Inert atmosphere
6.1: sodium ethanolate / N,N-dimethyl-formamide / 3 h / -5 - 5 °C / Inert atmosphere
View Scheme
Multi-step reaction with 6 steps
1.1: hydrogen bromide; sodium hydroxide / water; dichloromethane / 2 h / 30 - 35 °C / Inert atmosphere
1.2: 2 h / 35 - 40 °C
2.1: hexane / 4 h / 50 - 55 °C / Inert atmosphere
3.1: potassium hydroxide / isopropyl alcohol / 1 h / -5 - 5 °C / Inert atmosphere
4.1: potassium hydroxide / water; dichloromethane / 3 h / 10 - 15 °C
4.2: 3 h / 20 - 25 °C
5.1: isopropyl alcohol / 5 h / 55 - 60 °C / Inert atmosphere
6.1: potassium hydroxide / isopropyl alcohol / 2 h / 5 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 6 steps
1.1: sodium hydroxide; thionyl chloride / 1,2-dichloro-ethane; water / 3 h / 40 - 45 °C
1.2: 5 h / 70 - 75 °C
2.1: acetonitrile / 4 h / 60 - 65 °C / Inert atmosphere
3.1: sodium ethanolate / N,N-dimethyl-formamide / 5 h / -5 - 10 °C / Inert atmosphere
4.1: sodium hydroxide / water; dichloromethane / 3 h / 15 - 20 °C
4.2: 3 h / 20 - 25 °C
5.1: acetonitrile / 5 h / 50 - 55 °C / Inert atmosphere
6.1: sodium ethanolate / N,N-dimethyl-formamide / 3 h / -5 - 5 °C / Inert atmosphere
View Scheme
1,3,3-trimethyl-2-chloromethylcyclohexene

1,3,3-trimethyl-2-chloromethylcyclohexene

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: acetonitrile / 4 h / 60 - 65 °C / Inert atmosphere
2.1: sodium ethanolate / N,N-dimethyl-formamide / 5 h / -5 - 10 °C / Inert atmosphere
3.1: sodium hydroxide / water; dichloromethane / 3 h / 15 - 20 °C
3.2: 3 h / 20 - 25 °C
4.1: acetonitrile / 5 h / 50 - 55 °C / Inert atmosphere
5.1: sodium ethanolate / N,N-dimethyl-formamide / 3 h / -5 - 5 °C / Inert atmosphere
View Scheme
Multi-step reaction with 5 steps
1.1: acetonitrile / 4 h / 60 - 65 °C / Inert atmosphere
2.1: sodium ethanolate / N,N-dimethyl-formamide / 5 h / -5 - 10 °C / Inert atmosphere
3.1: potassium hydroxide / water; dichloromethane / 3 h / 10 - 15 °C
3.2: 3 h / 20 - 25 °C
4.1: isopropyl alcohol / 5 h / 55 - 60 °C / Inert atmosphere
5.1: potassium hydroxide / isopropyl alcohol / 2 h / 5 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 5 steps
1.1: 4 h / 105 - 110 °C / Inert atmosphere
2.1: sodium methylate / N,N-dimethyl-formamide / 1 h / 0 - 15 °C / Inert atmosphere
3.1: potassium hydroxide / water; dichloromethane / 3 h / 10 - 15 °C
3.2: 3 h / 20 - 25 °C
4.1: isopropyl alcohol / 5 h / 55 - 60 °C / Inert atmosphere
5.1: potassium hydroxide / isopropyl alcohol / 2 h / 5 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 5 steps
1.1: 4 h / 105 - 110 °C / Inert atmosphere
2.1: sodium methylate / N,N-dimethyl-formamide / 1 h / 0 - 15 °C / Inert atmosphere
3.1: sodium hydroxide / water; dichloromethane / 3 h / 15 - 20 °C
3.2: 3 h / 20 - 25 °C
4.1: acetonitrile / 5 h / 50 - 55 °C / Inert atmosphere
5.1: sodium ethanolate / N,N-dimethyl-formamide / 3 h / -5 - 5 °C / Inert atmosphere
View Scheme
1-hexadecylcarboxylic acid
57-10-3

1-hexadecylcarboxylic acid

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: magnesium chloride; di-tert-butyl dicarbonate / ethyl acetate / 5 h / 25 - 35 °C
2.1: selenium(IV) oxide; tert.-butylhydroperoxide / 18 h / 25 - 30 °C / Inert atmosphere
3.1: sodium t-butanolate / toluene / 0.5 h / 0 °C / Inert atmosphere
3.2: 3 h / Inert atmosphere
View Scheme
3-methyl-2-buten-1-ol
556-82-1

3-methyl-2-buten-1-ol

retinyl palmitate
79-81-2

retinyl palmitate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: magnesium chloride; di-tert-butyl dicarbonate / ethyl acetate / 5 h / 25 - 35 °C
2.1: selenium(IV) oxide; tert.-butylhydroperoxide / 18 h / 25 - 30 °C / Inert atmosphere
3.1: sodium t-butanolate / toluene / 0.5 h / 0 °C / Inert atmosphere
3.2: 3 h / Inert atmosphere
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

Hexadecanoic acid 2-hexadecanoyloxymethyl-3,6-dimethyl-5-[(1Z,3E)-2-methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-buta-1,3-dienyl]-6-[(1E,3E,5E)-4-methyl-6-(2,6,6-trimethyl-cyclohex-1-enyl)-hexa-1,3,5-trienyl]-cyclohex-3-enylmethyl ester

Hexadecanoic acid 2-hexadecanoyloxymethyl-3,6-dimethyl-5-[(1Z,3E)-2-methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-buta-1,3-dienyl]-6-[(1E,3E,5E)-4-methyl-6-(2,6,6-trimethyl-cyclohex-1-enyl)-hexa-1,3,5-trienyl]-cyclohex-3-enylmethyl ester

Conditions
ConditionsYield
at 80℃; for 120h; Kinetics; Further Variations:; Solvents; Temperatures; Dimerization;
retinyl palmitate
79-81-2

retinyl palmitate

13-cis-retinoic acid
4759-48-2

13-cis-retinoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: aq. 5percent KOH / ethanol / 0.5 h / Heating
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

all-trans-retinoic-acid
302-79-4

all-trans-retinoic-acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
View Scheme
Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

20,14-retro-Retinoic acid
138093-35-3

20,14-retro-Retinoic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
4: 1.) lithium diisopropylamide, HMPA / 1.) THF, hexane, -60 deg C, 5 min, 2.) THF, hexane, -70 deg C, 45 min
View Scheme
Multi-step reaction with 4 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
4: 1.) n-BuLi, diisopropylamine / 1.) THF, hexane, 0 deg C, 10 min, 2.) THF, hexane, -60 deg C, 5 min
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

14-ethyl-20,14-retro-retinoic acid
138093-38-6

14-ethyl-20,14-retro-retinoic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
4: 1.) lithium diisopropylamide, HMPA / 1.) THF, hexane, -60 deg C, 5 min, 2.) THF, hexane, -70 deg C, 45 min
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

14-isopropyl-20,14-retro-retinoic acid
138093-39-7

14-isopropyl-20,14-retro-retinoic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
4: 1.) lithium diisopropylamide, HMPA / 1.) THF, hexane, -60 deg C, 5 min, 2.) THF, hexane, -70 deg C, 45 min
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

methyl 14-ethyl-20,14-retro-retinoate
138093-44-4

methyl 14-ethyl-20,14-retro-retinoate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
4: 1.) lithium diisopropylamide, HMPA / 1.) THF, hexane, -60 deg C, 5 min, 2.) THF, hexane, -70 deg C, 45 min
5: 77 percent / diethyl ether / 20 h / 0 °C
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

methyl 14-isopropyl-20,14-retro-retinoate
138093-45-5

methyl 14-isopropyl-20,14-retro-retinoate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
4: 1.) lithium diisopropylamide, HMPA / 1.) THF, hexane, -60 deg C, 5 min, 2.) THF, hexane, -70 deg C, 45 min
5: 89 percent / diethyl ether / 0.5 h / 0 °C
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

13-cis-14-Ethylretinoic acid
138231-98-8

13-cis-14-Ethylretinoic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
4: 1.) lithium diisopropylamide, HMPA / 1.) THF, hexane, -60 deg C, 5 min, 2.) THF, hexane, -70 deg C, 45 min
5: 77 percent / diethyl ether / 20 h / 0 °C
6: 1.) MeONa, 2.) 10percent aq. KOH / 1.) MeOH, reflux, 7 h, 2.) EtOH, reflux
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

14-Ethylretinoic acid
138093-41-1

14-Ethylretinoic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
4: 1.) lithium diisopropylamide, HMPA / 1.) THF, hexane, -60 deg C, 5 min, 2.) THF, hexane, -70 deg C, 45 min
5: 77 percent / diethyl ether / 20 h / 0 °C
6: 1.) MeONa, 2.) 10percent aq. KOH / 1.) MeOH, reflux, 7 h, 2.) EtOH, reflux
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

13-cis-14-Isopropylretinoic acid
138231-99-9

13-cis-14-Isopropylretinoic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
4: 1.) lithium diisopropylamide, HMPA / 1.) THF, hexane, -60 deg C, 5 min, 2.) THF, hexane, -70 deg C, 45 min
5: 89 percent / diethyl ether / 0.5 h / 0 °C
6: 1.) NaH, 2.) 20percent aq. KOH, 18-crown-6 / 1.) DMF, 50 deg C, 90 min, 2.) EtOH, reflux
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

14-Isopropylretinoic acid
138093-42-2

14-Isopropylretinoic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
4: 1.) lithium diisopropylamide, HMPA / 1.) THF, hexane, -60 deg C, 5 min, 2.) THF, hexane, -70 deg C, 45 min
5: 89 percent / diethyl ether / 0.5 h / 0 °C
6: 1.) NaH, 2.) 20percent aq. KOH, 18-crown-6 / 1.) DMF, 50 deg C, 90 min, 2.) EtOH, reflux
View Scheme
retinyl palmitate
79-81-2

retinyl palmitate

(2Z,4E,6E,8E)-2-Ethyl-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid methyl ester
138232-01-6

(2Z,4E,6E,8E)-2-Ethyl-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 90 percent / aq. 10percent KOH / propan-2-ol; ethanol / 1.25 h / 90 °C
2: 58 percent / MnO2, NaCN / acetonitrile; acetic acid / 62 h / 20 °C
3: 77 percent / aq. 5percent KOH / ethanol / 0.5 h / Heating
4: 1.) lithium diisopropylamide, HMPA / 1.) THF, hexane, -60 deg C, 5 min, 2.) THF, hexane, -70 deg C, 45 min
5: 77 percent / diethyl ether / 20 h / 0 °C
6: MeONa / methanol / 7 h / Heating
View Scheme

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