Trifluoroacetyl chloride supplier

Name
TRIFLUOROACETYL CHLORIDE
EINECS 206-556-2
CAS No. 354-32-5
Article Data52
CAS DataBase
Density 1,335 g/cm3
Solubility
Melting Point -146ºC
Formula C2Cl F3 O
Boiling Point -27ºC
Molecular Weight 132.47
Flash Point 25.1°C
Transport Information
Appearance
Safety Corrosive to skin, eyes, and materials. When heated to decomposition it emits very toxic fumes of F⁻ and Cl⁻. See also FLUORIDES and CHLORIDES.
Risk Codes 14-35-37
Molecular Structure
Hazard Symbols C
Synonyms Acetylchloride, trifluoro- (6CI,7CI,8CI,9CI);2,2,2-Trifluoroacetyl chloride;Perfluoroacetyl chloride;Trifluoroacetyl chloride;
PSA 17.07000
LogP 1.31410

Synthetic route

: 75-90-1
2,2,2-Trifluoroacetaldehyde

: 354-32-5
trifluoracetyl chloride

Conditions

Conditions	Yield
	100%

: 407-25-0
trifluoroacetic anhydride

: 354-32-5
trifluoracetyl chloride

Conditions

Conditions	Yield
With 1-methyl-1H-imidazole; diethyl chlorophosphate	94%
With pyridine hydrochloride; trifluoroacetic acid

: 75-77-4
chloro-trimethyl-silane

: 72500-13-1
C6H9F3O4S

A: 354-32-5
trifluoracetyl chloride

B: 72500-12-0
Trimethylsilyl-1-butansulfonat

Conditions

Conditions	Yield
for 24h; Ambient temperature;	A n/a B 91%

...Expand

: 57160-01-7
1-Chlor-1,2,2,2-tetrafluorethansulfenylchlorid

A: 354-32-5
trifluoracetyl chloride

B: 754-13-2
trifluorothioacetyl fluoride

Conditions

Conditions	Yield
With Cu-cuttings In gas at 400℃; under 0.008 Torr;	A 1% B 89%

: 1493-13-6
trifluorormethanesulfonic acid

: 608-74-2
hexaiodobenzene

A: 354-32-5
trifluoracetyl chloride

B: 115162-16-8
C6I6(2+)*2CF3O3S(1-)

C: 115162-13-5
C6ClI5(1+)*2CF3O3S(1-)

Conditions

Conditions	Yield
With chlorine; trifluoroacetyl triflate at 25℃; for 4h; Product distribution; Mechanism; various oxidating agent;	A n/a B 88% C 7%
With chlorine; trifluoroacetyl triflate at 25℃; for 4h;	A n/a B 88% C 7%
With chlorin; trifluoroacetyl triflate at 25℃; for 4h;	A n/a B 88% C 7%

...Expand

: 93370-09-3
methanesulphonyltrifluoroacetic anhydride

: 75-36-5
acetyl chloride

A: 354-32-5
trifluoracetyl chloride

B: 5539-53-7
Acetyl methanesulfonate

Conditions

Conditions	Yield
at 50℃; for 1h; Yield given;	A n/a B 86.5%
at 50℃; for 1h; Yields of byproduct given;	A n/a B 86.5%

...Expand

: 76-05-1
trifluoroacetic acid

: 354-32-5
trifluoracetyl chloride

Conditions

Conditions	Yield
With phosphorus pentachloride In 1,2-dichloro-ethane for 3h;	81%
With benzoyl chloride at 200℃; for 3.5h;	50%
With phosphorus pentachloride

: 2925-25-9
trifluorothioacetic acid

A: 354-32-5
trifluoracetyl chloride

B: 132654-09-2
N-Chlorosulfuryltrifluoroacetimide

Conditions

Conditions	Yield
With isocyanate de chlorosulfonyle Ambient temperature;	A n/a B 66%

: 667-35-6
1,2-bis(trifluoroacetyl)hydrazine

A: 354-32-5
trifluoracetyl chloride

B: 58911-32-3
2,5-dichloro-1,1,1,6,6,6-hexafluoro-3,4-diaza-hexa-2,4-diene

Conditions

Conditions	Yield
With N,N-dimethylaniline hydrochloride; trichlorophosphate Heating; Yield given;	A n/a B 48%
With N,N-dimethylaniline hydrochloride; trichlorophosphate Heating; Yields of byproduct given;	A n/a B 48%

: 306-83-2
1,1,1-trifluoro-2,2-dichloroethane

A: 354-32-5
trifluoracetyl chloride

B: 76-05-1
trifluoroacetic acid

Conditions

Conditions	Yield
With oxygen; chlorine Irradiation.UV-Licht;

: 98-88-4
benzoyl chloride

: 76-05-1
trifluoroacetic acid

: 354-32-5
trifluoracetyl chloride

: 98-07-7
Benzotrichlorid

: 76-05-1
trifluoroacetic acid

: 354-32-5
trifluoracetyl chloride

Conditions

Conditions	Yield
With zinc(II) chloride

: 354-58-5
1,1,1-Trichloro-2,2,2-trifluoroethane

: 354-32-5
trifluoracetyl chloride

Conditions

Conditions	Yield
With sulfur trioxide

: 2923-18-4
sodium 2,2,2-trifluoroacetate

: 354-32-5
trifluoracetyl chloride

Conditions

Conditions	Yield
With p-toluenesulfonyl chloride

: 814-49-3
diethyl chlorophosphate

: 407-25-0
trifluoroacetic anhydride

A: 354-32-5
trifluoracetyl chloride

B: 650-09-9
O,O-Diethyl O-Trifluoroacetyl Phosphate

Conditions

Conditions	Yield
With 1-methyl-1H-imidazole Ambient temperature;

...Expand

: 407-25-0
trifluoroacetic anhydride

A: 354-32-5
trifluoracetyl chloride

B: 650-09-9
O,O-Diethyl O-Trifluoroacetyl Phosphate

Conditions

Conditions	Yield
With 1-methyl-1H-imidazole; diethyl chlorophosphate Ambient temperature; Yield given;

: 88099-83-6
1,1,1-trifluoro-2-chloroethylperoxyl radical

A: 354-32-5
trifluoracetyl chloride

B: 1-Chloro-2,2,2-trifluoro-ethanol

C: 147703-34-2
C2HClF3O

Conditions

Conditions	Yield
at 22.9℃; Rate constant; self-reaction;

...Expand

: 147703-34-2
C2HClF3O

: 354-32-5
trifluoracetyl chloride

Conditions

Conditions	Yield
With oxygen at 22.9℃; under 700 Torr; Product distribution;

: 306-83-2
1,1,1-trifluoro-2,2-dichloroethane

: 354-32-5
trifluoracetyl chloride

Conditions

Conditions	Yield
With oxygen; chlorine Oxidation; Photolysis;	102 %
Stage #1: 1,1,1-trifluoro-2,2-dichloroethane With oxygen at 20 - 40℃; under 1000 - 2000 Torr; Stage #2: for 8h; Conversion of starting material; UV-irradiation;
With ozone; copper(II) sulfate at 30℃; for 730.5h; Reagent/catalyst; Temperature; Irradiation;
With oxygen at 5℃; for 1h; Concentration; Temperature; Irradiation;

trifluoroacetate_of barium: trifluoroacetate_of barium

: 354-32-5
trifluoracetyl chloride

Conditions

Conditions	Yield
With phosphorus trichloride

trifluoroacetate_of sodium: trifluoroacetate_of sodium

: 354-32-5
trifluoracetyl chloride

Conditions

Conditions	Yield
With trichlorophosphate

: 75-90-1
2,2,2-Trifluoroacetaldehyde

: 7782-50-5
chlorine

A: 354-32-5
trifluoracetyl chloride

B: 75-46-7
trifluoromethan

C: 75-72-9
chlorotrifluoromethane

Conditions

Conditions	Yield
im UV-Licht;

...Expand

: 354-58-5
1,1,1-Trichloro-2,2,2-trifluoroethane

oxygen: oxygen

A: 354-32-5
trifluoracetyl chloride

B: 15719-64-9, 15719-76-3, 97762-63-5
methylammonium carbonate

Conditions

Conditions	Yield
UV-Licht.Irradiation;

...Expand

: 306-83-2
1,1,1-trifluoro-2,2-dichloroethane

oxygen: oxygen

A: 7647-01-0
hydrogenchloride

B: 354-32-5
trifluoracetyl chloride

C: 15719-64-9, 15719-76-3, 97762-63-5
methylammonium carbonate

D: 76-05-1
trifluoroacetic acid

Conditions

Conditions	Yield
im UV-Licht;

...Expand

: 306-83-2
1,1,1-trifluoro-2,2-dichloroethane

: 7782-50-5
chlorine

oxygen: oxygen

A: 7647-01-0
hydrogenchloride

B: 354-32-5
trifluoracetyl chloride

C: 15719-64-9, 15719-76-3, 97762-63-5
methylammonium carbonate

D: 76-05-1
trifluoroacetic acid

Conditions

Conditions	Yield
im UV-Licht;

...Expand

: 1004-47-3
3-chlorotrifluoro-1,2-oxathietane 2,2-dioxide

: 933-29-9
4-chlorotrifluoro-1,2-oxathietane 2,2-dioxide

A: 3935-49-7
chlorotrifluoroethylene oxide

B: 354-32-5
trifluoracetyl chloride

C: 354-27-8
chlorodifluoroacetyl fluoride

Conditions

Conditions	Yield
byproducts: SO2; at 245-255°C; detected by IR- and mass spectroscopy;
byproducts: SO2; at 245-255°C;

...Expand

: 102687-65-0
trans-1-chloro-3,3,3-trifluoropropene

A: 354-32-5
trifluoracetyl chloride

B: 2565-30-2
formyl chloride

C: 75-90-1
2,2,2-Trifluoroacetaldehyde

D: 19256-25-8
3,3,3-trifluoro-2-chloropropionaldehyde

E: 431-54-9
3,3,3-trifluoro-2-chloropropionyl chloride

Conditions

Conditions	Yield
With nitrogen; oxygen; chlorine at 21.84℃; under 700 Torr; UV-irradiation;

...Expand

: 102687-65-0
trans-1-chloro-3,3,3-trifluoropropene

A: 354-32-5
trifluoracetyl chloride

B: 2565-30-2
formyl chloride

C: 75-90-1
2,2,2-Trifluoroacetaldehyde

D: 19256-25-8
3,3,3-trifluoro-2-chloropropionaldehyde

E: 431-54-9
3,3,3-trifluoro-2-chloropropionyl chloride

F: 126266-75-9
3,3-dichloro-1,1,1-trifluoroacetone

Conditions

Conditions	Yield
With nitrogen; oxygen; chlorine at 21.84℃; under 700 Torr; UV-irradiation;

...Expand

: 102687-65-0
trans-1-chloro-3,3,3-trifluoropropene

A: 354-32-5
trifluoracetyl chloride

B: 2565-30-2
formyl chloride

C: 19256-25-8
3,3,3-trifluoro-2-chloropropionaldehyde

D: 431-54-9
3,3,3-trifluoro-2-chloropropionyl chloride

E: 126266-75-9
3,3-dichloro-1,1,1-trifluoroacetone

Conditions

Conditions	Yield
With nitrogen; oxygen; chlorine at 21.84℃; under 700 Torr; UV-irradiation;

...Expand

: 354-32-5
trifluoracetyl chloride

: 114351-53-0
2-Amino-3-trifluoromethylsulfanyl-benzoic acid

: 114351-18-7
2-Trifluoromethyl-8-trifluoromethylsulfanyl-benzo[d][1,3]oxazin-4-one

Conditions

Conditions	Yield
With 4-methyl-morpholine In dichloromethane for 20h; Ambient temperature;	100%

: 354-32-5
trifluoracetyl chloride

: 503-39-9
di-H-trifluoroethane-2-sulfonyl fluoride

: 121-44-8
triethylamine

: (Z)-1,1,1,4,4,4-Hexafluoro-3-hydroxy-but-2-ene-2-sulfonyl fluoride; compound with triethyl-amine

Conditions

Conditions	Yield
In diethyl ether at -70 - 20℃;	100%

...Expand

: 354-32-5
trifluoracetyl chloride

: 109-92-2
ethyl vinyl ether

: 1095142-49-6
4-chloro-4-ethoxy-1,1,1-trifluoro-3-butan-2-one

Conditions

Conditions	Yield
at -30℃; Product distribution / selectivity;	100%
at 0 - 25℃; for 3.95h; Product distribution / selectivity;	93%
at 0 - 25℃; for 3.95h; Product distribution / selectivity;	93%

: 354-32-5
trifluoracetyl chloride

: 109-92-2
ethyl vinyl ether

A: 59938-06-6, 17129-06-5
4-ethoxy-1,1,1-trifluoro-3-butene-2-one

B: 1095142-49-6
4-chloro-4-ethoxy-1,1,1-trifluoro-3-butan-2-one

Conditions

Conditions	Yield
With sodium hydroxide at -10 - 80℃; under 262.526 - 760.051 Torr; Product distribution / selectivity;	A 85% B 100%

...Expand

: 354-32-5
trifluoracetyl chloride

: 1190-91-6
4-dimethylamino-3-buten-2-one

: 3-dimethylaminomethylene-1,1,1-trifluoro-2,4-pentanedione

Conditions

Conditions	Yield
In dichloromethane at 0℃; for 2h; Inert atmosphere;	100%

: 354-32-5
trifluoracetyl chloride

: 31230-17-8
3-methyl-5-aminopyrazole

: 198213-31-9
3-trifluoroacetylamino-5-methylpyrazole

Conditions

Conditions	Yield
With triethylamine In 1,4-dioxane at 10 - 20℃;	99%

: 354-32-5
trifluoracetyl chloride

: 2407-68-3
3-dimethylaminoacrylonitrile

: 339011-85-7
2-((dimethylamino)methylene)-4,4,4-trifluoro-3-oxobutyronitrile

Conditions

Conditions	Yield
With pyridine In toluene Product distribution / selectivity; Cooling with ice; Inert atmosphere;	99%

: 354-32-5
trifluoracetyl chloride

: 1019453-85-0
2-(2,4-dimethylphenylsulphanyl)benzeneamine

: N-(2-(2,4-dimethylphenylthio)phenyl)-2,2,2-trifluoroacetamide

Conditions

Conditions	Yield
With sodium hydroxide In acetonitrile	98%

: 354-32-5
trifluoracetyl chloride

: 64-17-5
ethanol

: 383-63-1
ethyl trifluoroacetate,

Conditions

Conditions	Yield
at 35 - 58℃; for 1h; Temperature;	97.86%
With hydrogenchloride In water; ethyl acetate at 40 - 60℃; for 0.333333h; Temperature;

: 354-32-5
trifluoracetyl chloride

: 464-00-6
2-chloro-2,2-difluoroethanol

: 2-chloro-2,2-difluoroethyl trifluoroacetate

Conditions

Conditions	Yield
In N,N-dimethyl-formamide for 4h; Heating;	97%

: 354-32-5
trifluoracetyl chloride

: 2-(2-bromopyridin-3-yl) ethanamine

: 1310552-76-1
N-(2-(2-bromopyridin-3-yl)ethyl)-2,2,2-trifluoroacetamide

Conditions

Conditions	Yield
With pyridine In dichloromethane at 0 - 20℃; Inert atmosphere;	97%

: 354-32-5
trifluoracetyl chloride

: Hg(NSOF2)2

: 56697-78-0
sulfinyl difluoride trifluoroacetylimide

Conditions

Conditions	Yield
20°C, 12 h, shaking in autoclave;	96.5%
20°C, 12 h, shaking in autoclave;	96.5%

: 354-32-5
trifluoracetyl chloride

: 55759-55-2
1,1,1-trifluoro-3-(triphenylphosphoranylidene)-2-propanone

: Bismethylenetriphenylphosphorane

Conditions

Conditions	Yield
In toluene 1.) 110 deg C, 4 h, 2.) r.t., 1 h;	96%

: 354-32-5
trifluoracetyl chloride

: 4-((3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7-(8H)-yl)methyl)benzenamine

: 2,2,2-trifluoro-N-(4-((3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methyl)phenyl)acetamide

Conditions

Conditions	Yield
In acetonitrile at 55℃; for 0.416667h; Microwave irradiation;	96%

: 354-32-5
trifluoracetyl chloride

: 926-66-9
2-ethoxyprop-1-ene

: 144219-75-0
1,1,1-trifluoro-4-ethoxypent-3-en-2-one

Conditions

Conditions	Yield
With diethylamine In cyclohexane at 5 - 10℃; for 3h; Reagent/catalyst; Solvent; Temperature; Large scale;	96%

: 354-32-5
trifluoracetyl chloride

: 209466-99-9, 209810-40-2, 209810-47-9, 209810-48-0
9,10,11-Trimethoxy-3-methylsulfanyl-6,7-dihydro-5H-dibenzo[a,c]cyclohepten-5-ol

: Trifluoro-acetic acid 9,10,11-trimethoxy-3-methylsulfanyl-6,7-dihydro-5H-dibenzo[a,c]cyclohepten-5-yl ester

Conditions

Conditions	Yield
In pyridine	95.2%

: 354-32-5
trifluoracetyl chloride

: 56239-25-9
2-Oxa-3-azabicyclo<2.2.2>oct-5-ene hydrochloride

: N-(trifluoroacetyl)-2-oxa-3-azabicyclo<2.2.2>oct-5-ene

Conditions

Conditions	Yield
With triethylamine In dichloromethane for 12h;	95%

: 354-32-5
trifluoracetyl chloride

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 350-09-4
N-trifluoroacetyl-L-phenylalanine

Conditions

Conditions	Yield
In trifluoroacetic acid	95%

: 354-32-5
trifluoracetyl chloride

: 116-09-6
hydroxy-2-propanone

: trifluoroacetoxyacetone

Conditions

Conditions	Yield
at -30℃;	95%

: 354-32-5
trifluoracetyl chloride

: 61637-95-4
dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonothioate

: trifluoro-acetic acid 2,2,2-trichloro-1-(dimethoxy-thiophosphoryl)-ethyl ester

Conditions

Conditions	Yield
With triethylamine In dichloromethane at -20 - 20℃;	94.7%

: 354-32-5
trifluoracetyl chloride

: 151889-10-0
2-phenyl-5-methoxyltryptamine

: N-<2-(5-methoxy-2-phenylindol-3-yl)ethyl>trifluoroacetamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane for 3h; Ambient temperature;	94%
With triethylamine In dichloromethane

: 354-32-5
trifluoracetyl chloride

: 1217-80-7
2-(2-phenyl-1H-indol-3-yl)ethylamine

: N-<2-(2-phenylindol-3-yl)ethyl>trifluoroacetamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane for 3h; Ambient temperature;	94%
With triethylamine In dichloromethane

: 354-32-5
trifluoracetyl chloride

: 1217896-33-7
methyl 2-(4-{[4-(trifluoromethyl)-1,3-thiazol-2-yl]amino}phenyl)propanoate

: 1217896-34-8
methyl 2-(4-{(trifluoroacetyl)[4-(trifluoromethyl)-1,3-thiazol-2-yl]amino}phenyl)propanoate

Conditions

Conditions	Yield
With potassium carbonate In tetrahydrofuran for 4h; Reflux;	94%

: 354-32-5
trifluoracetyl chloride

: 122-00-9
para-methylacetophenone

: 720-94-5
4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione

Conditions

Conditions	Yield
Stage #1: para-methylacetophenone With sodium methylate In di-isopropyl ether at 50℃; for 6h; Stage #2: trifluoracetyl chloride In toluene at 40℃; for 2h; Reagent/catalyst; Concentration; Temperature; Solvent;	93%

: 354-32-5
trifluoracetyl chloride

: 109-92-2
ethyl vinyl ether

: 59938-06-6, 17129-06-5
4-ethoxy-1,1,1-trifluoro-3-butene-2-one

Conditions

Conditions	Yield
With pyridine In toluene at 0 - 5℃; for 4h; Temperature; Sealed tube;	92.3%
at 0 - 80℃; Product distribution / selectivity; thermolysis;	90.4%
at 10 - 80℃; for 8h; Product distribution / selectivity; Inert atmosphere; Industry scale;	87%
With 2,6-di-tert-butyl-4-methyl-phenol at 0 - 80℃; Product distribution / selectivity; thermolysis;	83%

: 354-32-5
trifluoracetyl chloride

: 31252-42-3
4-benzylpyperidine

: 157338-47-1
1-(trifluoroacetyl)-4-benzylpiperidine

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃; for 1h; Acylation;	92%

: 354-32-5
trifluoracetyl chloride

: 22195-47-7
2,2-dimethyl-1,3-dioxolane-4-methanamine

: N-[((+/-)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-2,2,2-trifluoroacetamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane Cooling with ice;	92%

Trifluoroacetyl chloride Chemical Properties

IUPAC Name: 2,2,2-Trifluoroacetyl chloride (354-32-5)
Synonyms: Trifluoroacetyl chloride ; Acetyl chloride, trifluoro- ; Perfluoroacetylchloride ; Trifluoro-acetylchlorid ;Trifluoroacetyl chloride cyl. with 800 ; Trifluoroacetylchloride97% ; Trifluoracetylchlorid ; Trifluoroacetic acid chloride
CAS: 354-32-5
Molecular Formula: C₂ClF₃O
Molecular Weight:132.47
Molecular Structure:
EINECS: 206-556-2
Product Categories: Chemical Synthesis;Compressed and Liquefied Gases;Synthetic Reagents
Mol File: 354-32-5.mol
Surface Tension: 18.3 dyne/cm
Density: 1.532 g/cm³
Melting point: -146 °C(lit.)
Enthalpy of Vaporization: 23.25 kJ/mol
Boiling Point: -27 °C(lit.)
Vapour Pressure: 3760 mmHg at 25°C
Vapor density: 4.6 (vs air)

Trifluoroacetyl chloride Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LC	inhalation	> 35300ppb/6H (35.3ppm)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	National Technical Information Service. Vol. OTS0536764,
mouse	LCLo	inhalation	35300ppb/6H (35.3ppm)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	National Technical Information Service. Vol. OTS0536764,
rat	LCLo	inhalation	35300ppb/6H (35.3ppm)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	National Technical Information Service. Vol. OTS0536764,

Trifluoroacetyl chloride Consensus Reports

Reported in EPA TSCA Inventory.

Trifluoroacetyl chloride Safety Profile

Hazard Codes C
Risk Statements 14-35-37
14: Trifluoroacetyl chloride (354-32-5) reacts violently with water
35: Trifluoroacetyl chloride (354-32-5) can causes severe burns
37: Irritating to the respiratory system
Safety Statements 26-36/37/39-45
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37/39: Trifluoroacetyl chloride (354-32-5) used, please wear suitable protective clothing, gloves and eye/face protection
RIDADR UN 3057 2.3
WGK Germany 2
RTECS AO7150000
F 4.5-19-21
Hazard Note Corrosive
HazardClass 2.3 .

Trifluoroacetyl chloride Standards and Recommendations

DOT Classification: 2.2; Label: Nonflammable Gas, Corrosive

Trifluoroacetyl chloride Specification

1.General Description: A colorless gas. Shipped as a liquid under own vapor pressure. Contact with the unconfined liquid may frostbite unprotected skin. Very toxic by inhalation and may severely irritate skin, eyes, and mucous membranes. Under prolonged exposure to fire or heat the containers may rupture violently and rocket.
2.Air & Water Reactions: Reacts avidly with water and with moisture in the air to give fumes of hydrogen chloride, a water-soluble toxic gas.
3.Reactivity Profile: Trifluoroacetyl chloride is incompatible with strong oxidizing agents, alcohols, amines, alkalis. Reacts vigorously with amines and alkalis. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
4.Health Hazard: Toxic; may be fatal if inhaled, ingested or absorbed through skin. Vapors are extremely irritating and corrosive. Contact with gas or liquefied gas may cause burns, severe injury and/or frostbite. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control may cause pollution.
5.Fire Hazard: Some may burn but none ignite readily. Vapors from liquefied gas are initially heavier than air and spread along ground. Some of these materials may react violently with water. Cylinders exposed to fire may vent and release toxic and/or corrosive gas through pressure relief devices. Containers may explode when heated. Ruptured cylinders may rocket.

Product Name

TRIFLUOROACETYL CHLORIDE

Synthetic route

Trifluoroacetyl chloride Chemical Properties

Trifluoroacetyl chloride Toxicity Data With Reference

Trifluoroacetyl chloride Consensus Reports

Trifluoroacetyl chloride Safety Profile

Trifluoroacetyl chloride Standards and Recommendations

Trifluoroacetyl chloride Specification

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