• Name

  Triisobutyl phosphate

• EINECS 204-798-3
• CAS No. 126-71-6
• Article Data26
• CAS DataBase
• Density 0.982 g/cm³
• Solubility 264mg/L at 25℃
• Melting Point
• Formula C₁₂H₂₇O₄P
• Boiling Point 261.2 ºC at 760 mmHg
• Molecular Weight 266.318
• Flash Point 125.8 ºC
• Transport Information
• Appearance Colorless transparent liquid
• Safety 36/37
• Risk Codes 43
• Molecular Structure
• Hazard Symbols Xi
• Synonyms Isobutylphosphate ((C4H9O)3PO) (6CI,7CI);Phosphoric acid, triisobutyl ester (8CI);Antifoam TIP;Daiguard 400;NSC 62222;Reomol TIBP;
• PSA 54.57000
• LogP 4.11230

Synthetic route

78-83-1

2-methyl-propan-1-ol

A

126-71-6

triisobutyl phosphate

B

3846-81-9

diphosphoric acid tetraisobutyl ester

Conditions

Conditions	Yield
With phosphorous; tetraethylammonium iodide In water at 50℃; Electrolysis;	A 4% B 81%

78-83-1

2-methyl-propan-1-ol

A

1189-24-8

diisobutyl phosphite

B

6303-30-6

diisobutyl phosphoric acid

C

126-71-6

triisobutyl phosphate

Conditions

Conditions	Yield
With sodium hypophosphite; copper dichloride at 24.9℃; for 148h;	A 5.6% B 66.6% C 27.8%

...Expand

78-83-1

2-methyl-propan-1-ol

126-71-6

triisobutyl phosphate

Conditions

Conditions	Yield
With pyridine; trichlorophosphate; benzene
With argon; phosphan; copper(l) chloride; copper dichloride In acetonitrile
With argon; phosphan; copper(l) chloride; copper dichloride In acetonitrile at 24.9℃; Rate constant; Thermodynamic data; Product distribution; E(excit.), ΔS(excit.);

13259-29-5

sodium isobutoxide

126-71-6

triisobutyl phosphate

Conditions

Conditions	Yield
With diethyl ether; trichlorophosphate
With phosphorus trichloride

1606-96-8

triisobutyl phosphite

126-71-6

triisobutyl phosphate

Conditions

Conditions	Yield
With 2-methyl-propan-1-ol; chlorine

1606-96-8

triisobutyl phosphite

A

126-71-6

triisobutyl phosphate

B

3846-81-9

diphosphoric acid tetraisobutyl ester

Conditions

Conditions	Yield
With iodoacetophenone; silver perchlorate In benzene for 0.316667h; Title compound not separated from byproducts;

17158-87-1

phosphorochloridic acid diisobutyl ester

78-83-1

2-methyl-propan-1-ol

126-71-6

triisobutyl phosphate

Conditions

Conditions	Yield
at 60℃; Rate constant; Thermodynamic data; activation energy, activation enthalpy, other temperature (40, 50, 70, 80 deg C);

78-83-1

2-methyl-propan-1-ol

A

126-71-6

triisobutyl phosphate

B

628-55-7

diisobutyl ether

Conditions

Conditions	Yield
With phosphan; copper dichloride In N,N-dimethyl-formamide at 59.9℃;

78-83-1

2-methyl-propan-1-ol

A

126-71-6

triisobutyl phosphate

B

513-36-0

isobutyryl chloride

Conditions

Conditions	Yield
With phosphan; chlorine at 20℃; Rate constant; Thermodynamic data; Ea, ΔS(excit.); var. temp.; also in the presence of pyridine;

13529-77-6

phosphonic acid diisobutyl ester

A

126-71-6

triisobutyl phosphate

B

75340-94-2

diphosphorus (IV)-oic acid tetraisobutyl ester

C

3846-81-9

diphosphoric acid tetraisobutyl ester

Conditions

Conditions	Yield
With sodium perchlorate In acetonitrile electrochemical oxidation, 2.4 A h; Pt anode, Ni cathode; Ag/AgNO3 reference electrode; Title compound not separated from byproducts;

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7647-01-0

hydrogenchloride

zinc(II) phosphide

78-83-1

2-methyl-propan-1-ol

80937-33-3

oxygen

A

6303-30-6

diisobutyl phosphoric acid

B

126-71-6

triisobutyl phosphate

C

513-36-0

isobutyryl chloride

D

7646-85-7

zinc(II) chloride

Conditions

Conditions	Yield
copper dichloride In further solvent(s) Kinetics;

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copper phosphide

78-83-1

2-methyl-propan-1-ol

A

126-71-6

triisobutyl phosphate

B

513-36-0

isobutyryl chloride

C

copper dichloride

Conditions

Conditions	Yield
With O2; CuCl2 In neat (no solvent) Kinetics; byproducts: H2O, HCl; the alcohol was loaded together with CuCl2 into the reactor and purged with an Ar-O2 mixture; then Cu3P was added and the mixt. reacted at 293 K, 323 K or 343 K;;

...Expand

109-72-8, 29786-93-4

n-butyllithium

126-71-6

triisobutyl phosphate

10092-77-0

diisobutyl butylphosphonate

Conditions

Conditions	Yield
In tetrahydrofuran; hexane at -78 - 0℃;	93%

126-71-6

triisobutyl phosphate

uranium(IV) perrhenate pentahydrate

[U(perrhenato)4(tri-iso-butyl phosphate)4]

Conditions

Conditions	Yield
In acetonitrile (N2 or Ar); ligand added to a soln. of U salt; crystd. overnight at room temp.; elem. anal.;	87%

126-71-6

triisobutyl phosphate

(232)thorium perrhenate*4H2O

[(232)Th(perrhenato)4(triisobutylphosphate)4]

Conditions

Conditions	Yield
In methanol addn. of phosphorus compd. to a soln. of thorium compd. in methanol; centrifugation, sepn., washing ppt. with methanol, centrifugation, sepn., evapn. of supernatant, drying in vac., dissolving in methanol, filtration, keeping at 4°C for 3 d; elem. anal.;	75%

UO2(2+)*2ReO4(1-)*H2O=[UO2(ReO4)2(H2O)]

126-71-6

triisobutyl phosphate

[UO2(ReO4)2(H2O)(tri-iso-butylphosphate)2]

bis[(μ2-perrhenato)(perrhenato)bis(tri-iso-butylphosphate)dioxouranium(VI)]

Conditions

Conditions	Yield
In ethanol soln. of P ligand (2 equiv.) in EtOH was added dropwise to soln. of U compd. in EtOH; evapd.; crystd. (hexane, away from direct sunlight); filtered; dried in air; elem. anal.;	A n/a B 70%

...Expand

302-17-0

chloral hydrate

126-71-6

triisobutyl phosphate

38457-66-8

(2,2,2-trichloro-1-hydroxy-ethyl)-phosphonic acid diisobutyl ester

Conditions

Conditions	Yield
In hexane Heating;	60%

europium(III) chloride hexahydrate

126-71-6

triisobutyl phosphate

89-05-4

1,2,4,5-benzenetetracarboxylic acid

Eu4(PM)3*3H2O*TIBP3

Conditions

Conditions	Yield
In ethanol; water To an aqueous soln. of EuCl3*6H2O was added an ethanolic soln. of pyromellitic acid and triisobutyl phosphate, neutralization with NH3 to pH 6 and warming to 30°C for 30-40 min.; Elem. anal.;	55%

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UO2(2+)*2ReO4(1-)*H2O=[UO2(ReO4)2(H2O)]

126-71-6

triisobutyl phosphate

[U(perrhenato)4(tri-iso-butyl phosphate)4]

Conditions

Conditions	Yield
In ethanol Irradiation (UV/VIS); allowed to evap. slowly in direct sunlight; decanted; elem. anal.;	35%

126-71-6

triisobutyl phosphate

134-32-7

1-amino-naphthalene

109556-56-1

diisobutyl-[1]naphthyl-amine

126-71-6

triisobutyl phosphate

91-59-8

naphthalen-2-ylamine

109554-95-2

diisobutyl-[2]naphthyl-amine

126-71-6

triisobutyl phosphate

789-24-2

9-Phenylfluorene

102889-20-3

9-Isobutyl-9-phenyl-fluoren

Conditions

Conditions	Yield
Multistep reaction;

109-72-8, 29786-93-4

n-butyllithium

126-71-6

triisobutyl phosphate

C12H26LiO3P

Conditions

Conditions	Yield
In diethyl ether at 0℃; Yield given;
In tetrahydrofuran; hexane at -78 - 0℃;

126-71-6

triisobutyl phosphate

83561-06-2

tris(2-methyl-1-propyl) phosphate radical

Conditions

Conditions	Yield
In water at 18.9℃; pulse radiolysis, pH 4.5-5; fast hydrolysis of alkyl radicals radiolytically formed;

126-71-6

triisobutyl phosphate

A

2466-73-1

Phosphorsaeure-sec.-butylester

B

6303-30-6

diisobutyl phosphoric acid

Conditions

Conditions	Yield
With sodium hydroxide In methanol; water at 100℃; for 2h; Title compound not separated from byproducts.;

126-71-6

triisobutyl phosphate

112292-29-2

diisobutyl (1-methylbutyl)phosphonate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: tetrahydrofuran; hexane / -78 - 0 °C 2: 89 percent / tetrahydrofuran; hexane / -78 - -20 °C View Scheme
Multi-step reaction with 2 steps 1: diethyl ether / 0 °C 2: 83 percent View Scheme

126-71-6

triisobutyl phosphate

10092-77-0

diisobutyl butylphosphonate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether / 0 °C 2: 73 percent / H3O(1+) View Scheme

51108-30-6

4-chloro-1H-isoindole-1,3(2H)-dione

117-21-5

3-chlorophthalic anhydride

126-71-6

triisobutyl phosphate

5329-14-6

aminosulfonic acid

A

4743-17-3

5-Chloroisatoic anhydride

B

63497-60-9

8-chloro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione

Conditions

Conditions	Yield
In water; formamide

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Triisobutyl phosphate Chemical Properties

Triisobutyl phosphate Uses

Triisobutyl phosphate Toxicity Data With Reference

Triisobutyl phosphate Consensus Reports

Triisobutyl phosphate Safety Profile

Triisobutyl phosphate Specification