1,1,1-trifluoroacetophenone
o-phenylenediamine dihydrochloride
2-phenyl-1H-benzoimidazole
Conditions | Yield |
---|---|
In N,N-dimethyl acetamide at 120 - 130℃; for 24h; | 99.6% |
o-phenylenediamine dihydrochloride
ethyl acetate
2-Methyl-1H-benzimidazole
Conditions | Yield |
---|---|
In ethylene glycol for 0.025h; microwave irradiation; | 99% |
o-phenylenediamine dihydrochloride
Ethyl propionate
2-ethylbenzimidazole
Conditions | Yield |
---|---|
In ethylene glycol for 0.025h; microwave irradiation; | 99% |
ethyl 2-hydroxyacetate
o-phenylenediamine dihydrochloride
2-(Hydroxymethyl)benzimidazole
Conditions | Yield |
---|---|
In ethylene glycol for 0.025h; microwave irradiation; | 97% |
Conditions | Yield |
---|---|
In water at 230℃; for 0.166667h; Microwave irradiation; Green chemistry; | 97% |
o-phenylenediamine dihydrochloride
chloroacetic acid ethyl ester
2-chloromethyl-1H-benzimidazole
Conditions | Yield |
---|---|
In ethylene glycol for 0.025h; microwave irradiation; | 95% |
o-phenylenediamine dihydrochloride
4-amino-benzoic acid
4-(1H-benzimidazol-2-yl)aniline
Conditions | Yield |
---|---|
With PPA for 0.0833333h; microwave irradiation; | 94.8% |
Ethyl hexanoate
o-phenylenediamine dihydrochloride
2-pentyl-1H-benzoimidazole
Conditions | Yield |
---|---|
In ethylene glycol for 0.025h; microwave irradiation; | 94% |
Conditions | Yield |
---|---|
In ethylene glycol for 0.025h; microwave irradiation; | 94% |
o-phenylenediamine dihydrochloride
diethyl malonate
bis(1H-benzo[d]imidazol-2-yl)methane
Conditions | Yield |
---|---|
In ethylene glycol for 0.025h; microwave irradiation; | 92% |
Conditions | Yield |
---|---|
In water for 0.0222222h; microwave irradiation; | 89.01% |
With hydrogenchloride In water for 4h; Inert atmosphere; Reflux; | 68% |
Stage #1: o-phenylenediamine dihydrochloride; acetic acid In water for 0.75h; Reflux; Stage #2: With ammonia In water | 60% |
o-phenylenediamine dihydrochloride
para-chlorobenzoic acid
2-(4-chlorophenyl)benzimidazole
Conditions | Yield |
---|---|
With PPA for 0.075h; microwave irradiation; | 88.63% |
trans-2-chlorocinnamic acid
o-phenylenediamine dihydrochloride
(E)-2-(2-chlorostyryl)-1H-benzo[d]imidazole
Conditions | Yield |
---|---|
In ethylene glycol for 5h; Condensation; Cycloaddition; Heating; | 88% |
(E)-2-methyl-3-(4-nitrophenyl)acrylic acid
o-phenylenediamine dihydrochloride
2-[1-methyl-2-(4-nitro-phenyl)-vinyl]-1H-benzoimidazole
Conditions | Yield |
---|---|
In ethylene glycol for 5h; Condensation; Cycloaddition; Heating; | 88% |
Conditions | Yield |
---|---|
In ethylene glycol for 5h; Condensation; Cycloaddition; Heating; | 86% |
4-nitro-trans-cinnamic acid
o-phenylenediamine dihydrochloride
(E)-2-(4-nitrostyryl)-1H-benzo[d]imidazole
Conditions | Yield |
---|---|
In ethylene glycol for 5h; Condensation; Cycloaddition; Heating; | 86% |
(E)-3-phenylacrylic acid
o-phenylenediamine dihydrochloride
(E)-2-styryl-1H-benzo[d]imidazole
Conditions | Yield |
---|---|
In ethylene glycol for 5h; Condensation; Cycloaddition; Heating; | 85% |
Conditions | Yield |
---|---|
Stage #1: bromocyane; o-phenylenediamine dihydrochloride With sodium hydrogencarbonate In water; acetonitrile at 0 - 20℃; Stage #2: With sodium carbonate In water; acetonitrile | 85% |
o-phenylenediamine dihydrochloride
benzoic acid
2-phenyl-1H-benzoimidazole
Conditions | Yield |
---|---|
With PPA for 0.075h; microwave irradiation; | 84.83% |
(E)-3-Nitrocinnamic acid
o-phenylenediamine dihydrochloride
2-(3-nitro-styryl)-1H-benzoimidazole
Conditions | Yield |
---|---|
In ethylene glycol for 5h; Condensation; Cycloaddition; Heating; | 84% |
o-phenylenediamine dihydrochloride
acetone
2,2,4-trimethyl-2,3-dihydro-1H-1,5-benzodiazepine
Conditions | Yield |
---|---|
In water at 20℃; for 7h; | 83% |
With sodium hydroxide for 18h; Ambient temperature; gas/solid reaction; |
-2-methyl-3-(4-chlorophenyl)prop-2-enoic acid
o-phenylenediamine dihydrochloride
2-[2-(4-chloro-phenyl)-1-methyl-vinyl]-1H-benzoimidazole
Conditions | Yield |
---|---|
In ethylene glycol for 5h; Condensation; Cycloaddition; Heating; | 83% |
3-(4-chlorophenyl)prop-2-enoic acid
o-phenylenediamine dihydrochloride
(E)-2-(4-chlorostyryl)-1H-benzo[d]imidazole
Conditions | Yield |
---|---|
In ethylene glycol for 5h; Condensation; Cycloaddition; Heating; | 82% |
-2-methyl-3-(4-methylphenyl)prop-2-enoic acid
o-phenylenediamine dihydrochloride
2-(1-methyl-2-p-tolyl-vinyl)-1H-benzoimidazole
Conditions | Yield |
---|---|
In ethylene glycol for 5h; Condensation; Cycloaddition; Heating; | 82% |
o-phenylenediamine dihydrochloride
chloroacetic acid
2-chloromethyl-1H-benzimidazole
Conditions | Yield |
---|---|
In water for 1.5h; Reflux; | 82% |
Conditions | Yield |
---|---|
With boric acid In toluene for 12h; Reflux; | 81% |
Conditions | Yield |
---|---|
In ethylene glycol for 5h; Condensation; Cycloaddition; Heating; | 80% |
2-methyl-3-(3-nitrophenyl)propenoic acid
o-phenylenediamine dihydrochloride
2-[1-methyl-2-(3-nitro-phenyl)-vinyl]-1H-benzoimidazole
Conditions | Yield |
---|---|
In ethylene glycol for 5h; Condensation; Cycloaddition; Heating; | 80% |
Conditions | Yield |
---|---|
With HCl In water N2 atmosphere; diamine dihydrochloride added to the soln. of MoCl5 in 12 M HCl (shaking) and dry HCl passed into the soln. for 1-2 h; redn. of the soln. volume to one third by gently heating; passing dry HCl into the soln. (ice-cooling); pptd. crystals vacuum-filtered, washed with ether/thionyl chloride (1:1) to avoid hydrolysis and dried over KOH; elem. anal.; | 80% |
(E/Z)-16-hydroxyhexadec-9-enoic acid
o-phenylenediamine dihydrochloride
Conditions | Yield |
---|---|
In ethylene glycol at 150 - 200℃; | 79% |
Empirical Formula: C6H10Cl2N2
Molecular Weight: 181.063 g/mol
EINECS: 210-418-7
Flash Point: 124.9 °C
Form: Tablet
Color: White to off-white
Storage tempreture: 2-8 °C
Melting point: 258 °C (dec.)(lit.)
Enthalpy of Vaporization: 49.45 kJ/mol
Boiling Point: 257 °C at 760 mmHg
Vapour Pressure: 0.0149 mmHg at 25 °C
Solubility: H2O: 1 tablet/10 mL, clear, colorless
Appearance: white to light pink powder
Stable: Stable. Incompatible with strong oxidizing agents.
Structure of o-Phenylenediamine dihydrochloride (CAS NO.615-28-1):
IUPAC Name: Benzene-1,2-diamine dihydrochloride
Product Categories of o-Phenylenediamine dihydrochloride (CAS NO.615-28-1): Powders;Core Bioreagents;Detection Substrates;Enzyme Substrates;Tablets;Peroxidase SubstratesELISA Substrates
o-Phenylenediamine dihydrochloride (CAS NO.615-28-1) has been used in the manufacture of dye.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
frog | LDLo | subcutaneous | 4gm/kg (4000mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 36, Pg. 140, 1930. | |
mouse | LD50 | intraperitoneal | 200mg/kg (200mg/kg) | National Technical Information Service. Vol. AD414-344, | |
mouse | LDLo | subcutaneous | 250mg/kg (250mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 36, Pg. 140, 1930. | |
rabbit | LD | subcutaneous | > 500mg/kg (500mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 36, Pg. 140, 1930. | |
rat | LD50 | intraperitoneal | 290mg/kg (290mg/kg) | Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the National Cancer Institut by Bio-Research Consultants, Inc. Vol. NCI-E-68-1311, Pg. 1973, | |
rat | LDLo | subcutaneous | 600mg/kg (600mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 36, Pg. 140, 1930. |
Reported in EPA TSCA Inventory.
Poison by intraperitoneal route. Questionable carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also m-PHENYLENEDIAMINE; o-PHENYLENEDIAMINE; p-PHENYLENEDIAMINE; p-PHENYLENEDIAMINE DIHYDROCHLORIDE; m-PHENYLENEDIAMINE HYDROCHLORIDE; p-PHENYLENEDIAMINESULFONIC ACID; 1,3-PHENYLENEDIAMINE-4-SULFONIC ACID and AMINES.
Hazard Codes: XnNT
Risk Statements: 22-40-43-51/53-68-50/53-36-25-20/21-36/37/38
R20/21:Harmful by inhalation and in contact with skin.
R22:Harmful if swallowed.
R25 :Toxic if swallowed.
R36:Irritating to eyes.
R36/37/38:Irritating to eyes, respiratory system and skin.
R40:Limited evidence of a carcinogenic effect.
R43:May cause sensitization by skin contact.
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R68:Possible risk of irreversible effects.
Safety Statements: 36/37-61-60-45-28-26
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28:After contact with skin, wash immediately with plenty of soap-suds.
S36/37:Wear suitable protective clothing and gloves.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
o-Phenylenediamine dihydrochloride ,its cas register number is 615-28-1. It also can be called p-Benzenediamine dihydrochloride ; m-Benzenediamine dihydrochloride ; Phenylenediamine dihydrochloride ;and 1,2-Benzenediamine, hydrochloride (1:2) .
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View