ObjectiveThis study aimed to determine the frequency, pattern and management of acute abdomen in patients with dengue fever.

AimsThis study aimed to explore the prevalence of, and factors associated with, uncontrolled diabetes mellitus (UDM) in a community setting in Pakistan.

ObjectiveTo explore the kind of care being received by a sample of middle income group subjects with diabetes in Karachi.

Childhood iron deficiency has a high incidence in Pakistan. Some but not all studies have shown that dietary iron deficiency may cause increased absorption of lead as both compete for the same transporters in the small intestine. Therefore, children in Pakistan, residing in heavily polluted citi...

BackgroundGenetic factors are involved in the development of T1D and studies have shown that the development of T1D also increases the risk of development of other autoimmune diseases.

BackgroundMultiple infections are the most common problem among HIV infected individuals. The prognostic impact of these co infections in HIV-population in resource-limited countries like Pakistan has not been fully elucidated. The aim of this study was to assess CD4 and hemoglobin (Hb) levels i...

Fetal hemoglobin (HbF) induction is a cost-effective therapeutic approach for the treatment of β-hemoglobinopathies like β-thalassemia and sickle cell anemia. The present study discusses the potential of thiourea derivatives as new class of compounds that induce the fetal hemoglobin production...

The mutagenicity of 2,4-diaminotoluene (DAT) in Ames's Salmonella/microsome test was remarkably enhanced by treatment with hydrogen peroxide. Therefore, identification of the major mutagenic reaction product of 2,4-DAT with hydrogen peroxide at room temperature has been performed. Red preci...

Four divalent metal coordination polymers containing bis(4-pyridylmethyl)piperazine (4-bpmp) and the ortho-dicarboxylate ligands phthalate (pht) or 4-methylphthalate (mpht) have been prepared by solvent diffusion or hydrothermal methods. {[Cu2(pht)2(H4-bpmp)2(H2O)2](NO3)2·H2O}n (1) and {[Cu2(ph...

Four coordination networks of composition [CuL2(H2O)(NO3)]·NO3·H2O (1) [CdL2(H2O)(NO3)]·NO3·H2O (2) (L=N,N′-bis(4-pyridylmethyl)urea), [CuL2(NO3)2]·2H2O·2EtOH (3) (L=N,N′-bis(3-pyridylmethyl)urea) and [CdL2(H2O)2]·2NO3 (4) (L=N,N′-bis(3-pyridylmethyl)urea) have been prepared. Structure...

A platinum(II)-DMSO complex has been incorporated into a thymidine based nucleoside through an N-3 pendant pyridyl nitrogen. Electrospray TOF-MS, 1H, 13C and 195Pt NMR methodologies all confirm the new structure. The complex exhibits differential stability in various media with DMSO solutions pa...

Three novel metal-organic frameworks based on the N-(4-pyridylmethyl)iminodiacetate (pmida2−), namely {[Cd(pmida)H2O]·1.8 H2O]}n (1), {[Cd(pmida)(H2O)]·2H2O}n·(2) and {[Zn(pmida)(H2O)]·2H2O}n (3), have been prepared and characterized by single crystal X-ray diffraction, IR, powder X-ray diff...

Hydrothermal reaction of a closed-shell divalent metal salt, a para aromatic dicarboxylate precursor, and the long-spanning dipyridyl ligand bis(4-pyridylmethyl)piperazine (4-bpmp) afforded three new coordination polymers, which were structurally characterized by single-crystal X-ray diffraction...

Hydrothermal synthesis has afforded divalent cadmium coordination polymers containing isophthalate (ip) or 5-methylisophthalate (mip) dicarboxylate ligands and bis(4-pyridylformyl)piperazine (4-bpfp) or bis(4-pyridylmethyl)homopiperazine (4-bpmh) tethers. {[Cd2(ip)2(H2O)2(4-bpfp)]·7H2O}n (1) di...

Hydrothermal reaction of zinc nitrate, aliphatic dicarboxylic acids, and the long-spanning hydrogen-bonding capable tethering ligand bis(4-pyridylmethyl)piperazine (4-bpmp) has produced seven coordination polymer solids that were characterized via single-crystal X-ray crystallography. [Zn(suc)(4...

Hydrothermal reaction of cadmium nitrate, 5-substituted isophthalic acid derivatives, and the long-spanning bis(4-pyridylmethyl)piperazine (4-bpmp) ligand afforded a series of crystalline coordination polymers whose topologies and mode of interpenetration depend critically on the nature of the 5...

Four Zn(II) coordination complexes, namely {[Zn(pmbm)2(tpa)]·H2O}n (1), {[Zn(pmbm)(phda)]·2(H2O)}n (2), [Zn(pmbm)(aze)]n (3), {[Zn(pmbm)(1,4-ndc)]·2(CH3OH)}n (4) [pmbm = 1-(4-pyridylmethyl)-benzimidazole, H2tpa = terephthalic acid, H2phda = phenylenediacetic acid, H2aze = azelaic acid, 1,4-nd...

Four Ni(II) reduced Schiff base complexes, {[Ni(L1)(HCOO)(H2O)](H2O)} (1), {[Ni(L2)(H2O)3](OAc)} (2), {[Ni(L3)(H2O)3](OAc)} (3) and {[Ni(L4)(HCOO)](H2O)} (4), have been synthesized by the reaction of N-(4-pyridylmethyl)-l-amino acid derivatives and Ni(OAc)2·4H2O under hydrothermal conditions. S...

The synthesis of a number of benzimidazole Schiff bases 3 and 3-oxo-pyrimido[1,2-a]benzimidazoles 4 in excellent yields by a one-step sequence from the reaction of 2-aminobenzimidazole under green chemistry conditions is described. Structural assignments of the new compounds as well as complete ...

A simple, facile, efficient and three-components procedure for the synthesis of pyrimido[1,2-a]benzimidazoles and pyrazolo[3,4-b]pyridines utilizing phenylsulfone synthon, under ultrasonic irradiation was developed.