A series of selenides bearing benzensulfonamide were investigated as inhibitors of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1). Potent inhibitory action, in the low nanomolar range, was detected against isoforms hCA II and VII, which are known to be involved in neuropathic pain modulat...

A series of twenty four hydroxy-trifluoromethylpyrazoline-carbonyl-1,2,3-triazoles and four hydrazones bearing benzenesulfonamide moieties was obtained by condensation of carboxyhydrazides with substituted 1,3-diketones. All the newly synthesized compounds were investigated as inhibitors of phys...

The sulfonamide compound, 4-methyl-N-(naphthalene-1-yl)benzene sulfonamide (abbreviated as 4MNBS) was synthesized from the reaction of 4-methyl benzene sulfonyl chloride with 1-naphthyl amine. The 4MNBS was characterized by FTIR, 1H NMR, 13C NMR, single crystal X-ray diffraction (XRD) and therma...

Three trimethylsilyl based malonate esters, bis(trimethylsilyl) 2-methyl-2-fluoromalonate (BTMSMFM), bis(trimethylsilyl) 2-ethyl-2-fluoromalonate (BTMSEFM) and bis(trimethylsilyl) 2-propyl-2-fluoromalonate (BTMSPFM), have been used as additives in 1.0 M LiPF6/ethylene carbonate (EC)-dimethyl car...

The intermediate generated by the DIBALH reduction of carboxylic acid esters reacts with trimethylsilyl trifluoromethanesulfonate (TMSOTf) in the presence of pyridine to afford the corresponding monosilyl acetals in good yields.

N-trimethylsilyl-bis(trifluoromethanesulfonyl)imide (TMSNTf2) was readily prepared from allyltrimethylsilane and bis(trifluoromethanesulfonyl)imide. It was shown to complex carbonyl groups much more effectively than trimethylsilyl triflate. As a result, TMSNTF2 was found to be superior to TMSOTf...

One-step aldol condensation of methyl acetate with formaldehyde (or trioxane) for preparing methyl acrylate at 623 K–653 K has stimulated researchers’ attention in recent years. Herein, a new methodology for one-step synthesis of methyl acrylate from methyl acetate and trioxane promoted by gen...

Ozone initiated oxidation of tetrachloro-o-benzoquinone (3,4,5,6-Tetrachlorocyclohexa-3,5-diene-1,2-dione, TCCD) in aqueous system catalyzed by different loadings of cesium oxide supported on metal oxides namely; Al2O3, SiO2 and TiO2 was investigated. Catalyst materials were characterized using ...

The preconcentration of trace elements, namely CaII, CdII, CoII, CrIII, CuII, FeIII, MnII, NiII, PbII, PdII, PdIV and UVI, by complexation with sulphonated azo-dyes and retention on an ion-exchange resin was studied. CuII was chosen as a reference metal ion and its uptake efficiencies with 11 di...

A review is presented to evaluate existing information on genotoxicity and carcinogenicity testing of various aromatic aminosulphonic acids (AASAs). A great variety of water-soluble azo dyes can form aromatic phenyl- or naphthyl-aminosulphonic acids by chemical and enzymatic reduction. AASAs are...

Titrations based on both complex formation and ion-pair formation principles have been used in assaying nine anionic azo dyes, namely C.I. 13900, C.I. 15685. C.I. 15705, C.I. 15710, C.I. 16680, C.I. 18744, C.I. 18760, C.I. 18821 and Calmagite. The results show that the titrations of the dye anio...

Arsenic is widely distributed in the environment. Many human cancers, including urothelial carcinoma (UC), show a dose-dependent relationship with arsenic exposure in the south-west coast of Taiwan (also known as the blackfoot disease (BFD) areas). However, the molecular mechanisms of arsenic-me...

Groups of male Sprague-Dawley rats were maintained on a basal diet containing 0.05% 3′-methyl-4-dimethylaminoazobenzene (3′-MeDAB) for 9 weeks. The diets of these groups were supplemented at certain stages of the study with retinoic acid, butylated hydroxytoluene (BHT), or sorbic acid. In othe...

The localized surface plasmon resonance (LSPR) mediated enhanced chemical activity can be entitled as a promising strategy for efficient solar to chemical energy conversion. To tune the selectivity of a desired product in a chemical reaction is of paramount importance yet a great challenge. In t...

The non-ionic surfactant, Tween 80 (T80) a material with promising applications in the pharmaceutical, cosmetic, and food industries, has been explored here for the design of novel nanostructures (NS). We report here a direct one-pot seedless green method for the synthesis of gold-silver (AuAg) ...

Avoidance behaviour offers a highly relevant information as it reveals the ability to avoid (or not) possible toxic compounds in the field, hence it provides information on reasons for the presence/absence in the field. The earthworm Eisenia fetida was used to study avoidance behaviour to four s...

Electric conduction in PVC-stabilized with dibutylin laurate–maleate has been investigated. In the low voltage region, the conduction was found to be due to thermally generated carriers. At higher voltages, the conduction mechanism was identified as Poole–Frenkel type. The charge carriers inje...

Polyvinyl acetate vinyl laurate copolymer (PVAcVL) is a useful component of gum base for chewing gum production. The safety of PVAcVL was examined in a 4-week and a 13-week oral toxicity study in rats. Finely powdered PVAcVL was administered with the diet at levels of 1.25%, 2.0% and 5% in the 4...

In the present study, we established for the first time a simple method for the preparation of silver nanoparticles (Ag NPs) using saturated fatty acid and tryptophan as capping and reducing agent, respectively. The -NH2 group of tryptophan and the carboxylate group of saturated long chain carbo...

SummaryBackground & aimsβ-hydroxy-β-methylbutyrate (HMB) is purported as a key nutritional supplement for the preservation of muscle mass in health, disease and as an ergogenic aid in exercise. Of the two available forms of HMB (calcium (Ca-HMB) salt or free acid (FA-HMB)) – differences in pl...