A multidimensional chromatographic strategy has been developed and optimized with the purpose of identifying different odorants potentially relevant to the aroma and flavor of aged wines from Madeira or Sherry. Different techniques of extraction and fractionation were studied in order to get cle...

A novel series of potent and specific MMP-2,3,9,13 inhibitors has been obtained by modulation on solid phase by α and aryl substitutions on 3-arylthio-N-hydroxy-propionamides starting from itaconic acid.

Anticonvulsant drugs are used to treat a wide range of non-epileptic conditions, including chronic pain. The aim of the present experiments was to examine analgesic activity of three new 3,3-diphenyl-propionamides, which had previously demonstrated anticonvulsant activity in the MES (maximal ele...

Strontium contained biomaterials have been reported as a potential bioactive material for bone regeneration, as it reduces bone resorption and stimulates bone formation. In the present investigation, the bioactive glasses were designed to partially substitute SrO for SiO2 in Na2O–CaO–SrO–P2O5...

Single crystals of pure bis (thiourea) strontium chloride (BTSC) have been grown by slow evaporation method. The solubility and meta-stable zone width of the crystals have been found to have direct relation with temperature. Orthorhombic structure and Pna21 space group of the crystals have been ...

This study reports syntheses of d-allose 6-phosphate (All6P), d-allulose (or d-psicose) 6-phosphate (Allu6P), and seven d-ribose 5-phosphate isomerase (Rpi) inhibitors. The inhibitors were designed as analogues of the 6-carbon high-energy intermediate postulated for the All6P to Allu6P isomeriza...

An enzymatic method for ready access to d-sedoheptulose-7-phosphate on a preparative scale was developed, based on the irreversible transketolase-catalyzed reaction: β-hydroxypyruvate + d-ribose-5-phosphate → d-sedoheptulose-7-phosphate. d-Sedoheptulose-7-phosphate disodium salt was obtained i...

Photoreduction of 9,10-phenanthrenequinone (PQ) in the presence of p-substituted N,N-dimethylanilines and polymethylbenzenes affords corresponding phenolethers as primary products. In the subsequent process shielded from light, phenolethers, which were formed by photoreaction of PQ with N,N-dime...

Synthesis of both enantiomers of 2-bromohexadecanoic acid is described by diastereoselective bromination of esters (+)- and (−)-3 followed by removal of the chiral auxiliary. The absolute configuration of the acids is confirmed by an independent chemical synthesis from chiral pool precursors.

The efficient preparation of enantiomerically pure (R)- and (S)-2-bromohexadecanoic acids with e.e.>95% through resolution with the use of a recoverable chiral auxiliary is described. The procedure involves three reactions: Steglich esterification, DIBAL reduction, and Sharpless oxidation. The a...

Surfaces of a Wyoming SWy-2 sodium montmorillonite were modified using microwave radiation through intercalation with the cationic surfactants octadecyltrimethylammonium bromide, dimethyldioctadecylammonium bromide, and methyltrioctadecylammonium bromide by an ion exchange mechanism. Changes in ...

Raman microprobe spectra of the clay mineral Wyoming SWy-2-sodium montmorillonite intercalated with the surfactants, methyltrioctadecylammonium bromide (TOMA) dimethyldiotadecylammonium bromide (DODMA) and octadecyl-trimethylammonium bromide (ODTMA), have been measured in the CH2 stretching regi...

Water purification is of extreme importance worldwide. p-Nitrophenol was used as a test chemical to design and test an organoclay for the removal of p-nitrophenol from an aqueous solution. Synthesis of the organoclay with methyltrioctadecylammonium bromide [CH3(CH2)17]3NBr(CH3) labeled as MTOAB ...

The effect of polymerization parameters such as crosslinking degree, solvent and porogen, on the surface area, pore structure, morphology and protein retention capacities of 2-(diethylamino)ethyl methacrylate-co-ethylene glycol dimethacrylate polymers obtained by photopolymerization was studied....

We present the synthesis and characterization of a series of pH-responsive hydrogel nanoparticles based on crosslinked 2-(diethylaminoethyl) methacrylate and poly(ethylene glycol) methyl ether methacrylate (P(DEAEMA-g-PEGMA)). Variants of this polymer were created using t-butyl methacrylate (P(D...

The pH-responsive cellulose-g-poly[2-(diethylamino)-ethyl methacrylate] (cellulose-g-PDEAEMA) copolymers were successfully synthesized by atom transfer radical polymerization (ATRP) in the ionic liquid 1-allyl-3-methylimidazolium chloride ([AMIM]Cl). As the functional monomer 2-(diethylamino)eth...

Polarized luminescence and flow birefringence methods were used in the studies of structural and dynamic characteristics of 2-(diethylamino)ethyl methacrylate and 2-deoxy-2-methacrylamido-d-glucose copolymers with varied content of cationic monomer units while changing temperature, pH and ionic ...

Copolymers containing 2-(N,N-diethylamino)ethyl methacrylate (DEAEMA) and poly(ethylene glycol) methyl ether methacrylate with Mn = 500 g mol−1 (PEGMA500) are one of the most promising combinations of smart polymers with biocompatibility character for uses in medical applications. The homo and t...

The nitroxide-mediated polymerisation (NMP) of poly(ethylene glycol) methyl ether methacrylate (PEGMA) with a small amount of styrene (S) as a comonomer was performed in water at 90 °C using 2,2'-azobis [2-(2-imidazolin-2-yl)propane]dihydrochloride (VA-044) as initiator and N-tert-butyl-N-...

The reduced graphene oxide-poly-(2-(dimethylamino)ethyl methacrylate)-Pt/Ag (RGO-PDMAEMA-Pt/Ag) nanoscrolls were prepared by rolling up the RGO-PDMAEMA-Pt/Ag sheets under freezing conditions. The compositions and structures of RGO-PDMAEMA-Pt/Ag sheets and nanoscrolls were characterized by Fourie...