The atmospheric concentrations of chlorodifluoromethane (HCFC-22) have been continuously measured for over a decade in long-term monitoring experiments. Comparison of these data with the industrial and regulatory databases of production and sales indicates that containment of this material is im...

The density of the binary mixture 40/60 wt% of monochlorodifluoromethane (HCFC 22) and 1-chloro-1,1-difluoroethane (HCFC 142b) in the liquid phase, has been measured between 300 and 370 K and pressures up to 19 MPa, with an oscillating fork densimeter, operating in a relative mode. Toluene and v...

Taiwan, a small island country located in the southeastern rim of Asia, is playing a vital role of mitigating hydrochlorofluorocarbons (HCFCs) mitigation, although it is not a signatory to the Montreal Protocol. Furthermore, the Government has established a ministry-level organization, National ...

Saturated liquid densities and vapor pressures of HCFC 225ca and HCFC 225cb were measured at temperatures from 280 to 400 K by a magnetic densimeter coupled with a variable volume cell; 28 and 36 measurements were obtained, respectively. The experimental uncertainties in temperature, pressure, a...

A blend of the hydrochlorofluorocarbon isomers HCFC-225ca and HCFC-225cb has been proposed as a potential substitute for CFC-113, an important solvent and cleaning agent. The toxicity following repeated inhalation of an HCFC-225 isomer mixture was assessed in male Crl:CDBR rats. Three groups of ...

In our continuing efforts into designing boronic acid-based sensors that recognize cell-surface carbohydrates, it has been necessary to examine various factors that affect the binding affinity between a boronic acid moiety and a diol. The current prevailing view is that the strongest boronic aci...

9α-Hydroxyandrost-4-ene-3, 17-dione 1, when allowed to react with dipotassium acetylide in tetrahydrofuran, resulted, after chromatographic separation, in 4-methyl-19-norandrosta-4, 9-diene-1, 17-dione 2, 4ξ-methyl-19-norandrosta-5(10), 9(11)-diene-1, 17-dione 3. 4-methyl-17α-ethynyl-17β-hyd...

A series of novel chiral aminophosphine ligands with a 5,5,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl backbone (H8-MAPs) have been synthesized. The application of these ligands in asymmetric allylic substitutions was examined and higher enantioselectivity was observed than that by using the pa...

The total syntheses of penmacric acid and its three stereoisomers were accomplished through the intermolecular radical addition reaction of the 4-pyrrolidyl radical derived from trans-4-hydroxy-l-proline. Furthermore, 1′,3-diepi-penmacric acid was synthesized stereoselectively via double stereo...

In the framework of the EUROfusion Consortium the Helium Cooled Pebble Bed (HCPB) breeding blanket (BB) is being developed. A blanket attachment system is also under development, which allows the integration of the BB into the EU DEMO tokamak. The blanket attachment system is thereby responsible...

Extremely endangered wildlife can be effectively protected by ex situ conservation programs. Despite that, the effects of human activity on the health of captive populations are still unclear. Using reduced representation bisulfite sequencing and RNA-seq, we assessed epigenetic and gene transcri...

Although clinical management of melanoma has changed considerably in recent years, intrinsic treatment resistance remains a severe problem and strategies to design personal treatment regimens are highly warranted. We have applied a three-dimensional (3D) ex vivo drug efficacy assay, exposing dis...

In a recently published and validated definition of fluid overload (FO), grade ≥ 2 FO was significantly associated with an increased risk of nonrelapse mortality (NRM) after unmodified and haploidentical allogeneic hematopoietic cell transplantation (allo-HCT) using calcineurin inhibitor (CNI)-...

ABSTRACTThe aim of this study was to evaluate the ex vivo and in vivo studies immune potential of α- and κ-casein. Ex vivo, naïve mouse splenocytes were stimulated with α- or κ-casein. After 120 h of culture, the proliferation index (PI), determined by 3-(4,5 dimethylthiazol-2yl)-2,5-dipheny...

Since the death of Steve Jobs, Apple has distributed eleven quarterly dividends. Of these, cash was paid 7 days after the ex-dividend date on nine occasions, and twice after 8 days. However, it used to pay cash at least 18 days after the ex-dividend date. When examining the whole market, firms t...

The technologies related to ex vivo models and lab-on-a-chip devices for studying the regeneration of brain, spinal cord, and peripheral nerve tissues are essential tools for neural tissue engineering and regenerative medicine research. The need for ex vivo systems, lab-on-a-chip technologies an...

Ex-post evaluations of benefit-cost analyses (BCAs) of transportation projects are scarce in the literature. If conducted frequently, they could reveal the extent to which objectives are achieved and may give inputs that can improve the quality of ex-ante BCAs. We first explain the usefulness of...

Bacterial infections and antibiotic resistant bacteria have become a growing problem over the past decade. As a result, the Centers for Disease Control predict more deaths resulting from microorganisms than all cancers combined by 2050. Currently, many traditional models used to study bacterial ...

Traditionally, futures Minimum Variance Hedge Ratios (MVHRs) are determined ex post. In this paper, we derive 3 increasingly realistic ex ante MVHRs, based on the carry cost and the Vasicek model. The hedging performance of the most realistic ex ante MVHR determination method is compared to, and...

Cationic polyamidoamine dendrimers are known to be highly branched cascade polymers. Tripeptide growth factor, glycyl-l-histidyl-l-lysine (GHK), was employed as a ligand for activation or attachment of cells from a rat hepatoma cell line, H4-H-E-C3, and immobilized at the terminus of the dendrim...