Novel polymeric complexes with a potentially bidentate ligand N-[β-(ethylamino)] acrylamide (EA), formed by amidation of 1,2-diaminoethane with acryloyl chloride were synthesized and characterized on the basis of elemental analyses, IR, 1H NMR, UV–Vis, magnetic susceptibility measurements, ESR...

In this work, a new class of highly potent antituberculosis agents, 1-substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their oxa and selanyl analogs, is described. The minimal inhibitory concentration (MIC) values reached 1 μM (0.36–0.44 μg/mL) against Mycobacterium tuberculosis ...

1-Substituted-5-alkylsulfanyl-1H-tetrazoles are well known class of organic substances with various applications in medicinal chemistry or photographic industry. Their selenium analogues, 1-substituted-5-alkylselanyl-1H-tetrazoles are, however, much less explored because of the lack of suitable ...

Reaction of 5-arylethynyl-2-methyl-2H-tetrazoles (acetylene tetrazoles) with arenes under the action of Brønsted superacid CF3SO3H or acidic zeolite HUSY CBV-720 gives rise to E-/Z-5-(2,2-diarylethenyl)-2-methyl-2H-tetrazoles, as products of hydroarylation of acetylene bond, in yields up to 98% ...

The syntheses of 1-(4-methoxyphenyl)-4-methyl-1H-tetrazol-5(4H)-thione 1a, 1-methyl-4-phenyl-1H-tetrazole-5(4H)-thione 1b, 1-(4-chlorophenyl)-4-methyl-1H-tetrazol-5(4H)-thione 1c, 1-methyl-4-(4-nitrophenyl)-1H-tetrazol-5(4H)-thione 1d were carried out and their electronic absorption spectra were...

In this paper, we report the synthesis of a biphenyl molecule containing tetrazole and triazolone moieties (MTBT) and confirmed its structure by elemental analyses, FT-IR, 1H & 13C NMR, GC-MS in addition to single crystal X-ray diffraction study. The molecular geometry, vibrational frequencies a...

A New and efficient magnetic nanocatalyst has been fabricated via covalent grafting of an aza-crown ether Cu(II) complex on silica coated iron oxide support. The above mentioned magnetic nanocatalyst has been characterized by various techniques such as SEM, TEM, XRD, FT-IR, TGA and ICP. After pr...

Benzoylhydrazine based Schiff base-ligated two new copper(II) complexes, [Cu(L1)2] (1) and [Cu(L2)2] (2) were synthesized by the reaction of Cu(CH3COO)2·H2O with respective Schiff base ligand 1-[(4-nitrophenyl)ethylidene] benzohydrazide (HL1) or 1-[(4-methoxyphenyl)ethylidene] benzohydrazide (H...

A series of 4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5(3)-(6-methylpyridin-2-yl)imidazoles and -pyrazoles 14a–c, 15a–c, 16a, 16b, 19a–d, 21a, and 21b has been synthesized and evaluated for their ALK5 inhibitory activity in an enzyme assay and in a cell-based luciferase reporter assay. Among the...

Branched cyclomalto-oligosaccharides are formed when pullulanase from Bacillus acidopullulyticus is incubated with α-maltosyl fluoride (α-G2F) as substrate in the presence of cyclomalto-oligosaccharides as acceptor. It was shown by enzymic and chemical methods that the structures of these bran...

The physicochemical and biological properties of the new branched cyclomaltooligosaccharides (cyclodextrins; CDs), 2-O-α-d-galactosyl-cyclomaltohexaose (2-O-α-d-galactosyl-α-cyclodextrin, 2-Gal-αCD) and 2-O-α-d-galactosyl-cyclomaltoheptaose (2-O-α-d-galactosyl-β-cyclodextrin, 2-Gal-βCD),...

The performance adjustment of known response motifs is important to further expand their practical applications. In this study, a fluorescent probe based on nitrobenzofurazan response motif anchored structurally asymmetric naphthorhodamine, named NRH-NBD, has been reported for the rapid and sele...

A simple novel dihydrophenazine-based chemosensor R has been developed for the detection of SO32− in DMSO-H2O solution with turn-on fluorescence. Upon the addition of sulfite, the ICT (intramolecular charge transfer) system of the probe was destroyed owing to the nucleophilic addition of sulfite...

Sulfite is a commonly used preservative in food products, alcoholic beverages and pharmaceutical products. We investigated the effect of sulfite, on locomotor activity as well as the relationship of these effects with oxidant and antioxidant capacities, cPLA2 enzyme activity. Thirty male Wistar ...

This study highlights a green approach for the reduction of graphene oxide (GO) using the ultraviolet/sulfite advanced reduction process (UV/sulfite process). X-ray photoelectron spectroscopy (XPS) provided a strong evidence on the efficient reduction of GO by increasing the C/O ratio from 2.0 t...

We report a process using NiFe2O4 nanocatalyst for the heterogeneous activation of sulfite ions for estriol (E3) oxidation. This NiFe2O4-sulfite system consisted of NiFe2O4 as an catalyst, sulfite as a reductant, O2 as an oxidant, and oxysulfur radicals (SO3−, SO4− and SO5−) and hydroxyl radical...

This study was focused on the sulfite-sulfate oxidation mechanisms in the nitrite-sulfite mixed solutions. Results showed that the oxidation rate of sulfite was first order with respect to the sulfite or oxygen concentration in the sulfite solution, while the oxidation rate of sulfite was accele...

BackgroundDiagnostic delay contributes to high morbidity and mortality in infective endocarditis. A readily available diagnostic marker of infective endocarditis is desirable. S-procalcitonin has been proposed as a candidate, but data on its yield are conflicting. We tested its diagnostic value ...

Background/AimsVCH-759 is a non-nucleoside inhibitor of HCV RNA-dependent polymerase with sub-micromolar IC50 values versus genotype 1a/1b replicons.

Microbial iron transport studies of the structure and conformation dependent ferrichrome uptake system in Ustilago sphaerogena have been limited previously to kinetically labile metal ions such as the native ferrichrome complex and the aluminum(III) and gallium(III) analogs. Although two coordin...