Collagen is a major structural protein, with properties such as low toxicity, low immune response and promoting cellular growth. If there is an excess of collagen accumulation, especially in the myocardium it leads to fibrosis, which in turn impairs the normal functioning of the myocardial tissu...

Currently, l-serine is mainly produced by enzymatic conversion, in which serine hydroxymethyltransferase (SHMT) is the key enzyme, suggesting the importance of searching for a SHMT with high activity. Shewanella algae, a methanol-utilizing marine bacterium showing high SHMT activity, was selecte...

The interactions between dopamine hydrochloride (DH) and nicotinamide (NA) in aqueous solution were studied using CV, NMR and quantum chemistry calculations. According to the cyclic voltammetry and the 1H NMR spectra, it was found that the hydrogen bond and π-π stacking between DH and NA were ...

Objective and patientsWe report on two new cases of serine deficiency due respectively to 3-phosphoglycerate dehydrogenase (PHGDH) deficiency (Patient 1) and phosphoserine aminotransferase (PSAT1) deficiency (Patient 2), presenting with congenital microcephaly (

Single crystal of l-serine methyl ester hydrochloride (LSMEHCl), was grown using slow evaporation solution growth technique. The grown crystal was confirmed by single crystal X-ray diffraction and the presence of functional groups were identified by FT-IR analysis. From the Optical transmission ...

The interactions of l-serine and l-threonine with drug metformin hydrochloride (Metformin-HCl) as a function of temperature have been investigated by combination of volumetric and acoustic methods. Densities and speeds of sound of l-serine and l-threonine in (0.00, 0.03, 0.045, 0.06 and 0.09) mo...

The volumetric, acoustic and viscometric properties are used for investigating the interactions of l-serine and l-arginine in aqueous solutions of a vitamin, namely, thiamine hydrochloride, over a temperature range of (293.15–313.15) K and at atmospheric pressure. The limiting apparent molar vo...

A β-glucosidase gene from Bacillus cellulosilyticus was expressed in Escherichia coli BL21 and characterized. The recombinant enzyme (BcBgl1A) showed the optimal activity at 40 °C, and the half-life of BcBgl1A activity at 40 °C was 24 h. BcBgl1A was sensitive to heat and exhibited obvious col...

A new platform based on 4-Fluoro-3-nitrophenyl (FNP) grafted gold disk electrode prepared via electrochemical reduction of 4-fluoro-3-nitrobenzene diazonium ion has been developed and utilized for biosensor fabrication. Anti-interleukin-2 (anti-IL2) antibody has been covalently immobilized onto ...

The photoprocesses of nifedipine, a 4-(2-nitrophenyl)-1,4-dihydropyridine, and nimodipine and nitrendipine, two 3-nitrophenyl Hantzsch-type analogues, were studied by steady-state and time-resolved methods. The intramolecular photoreduction of nifedipine into its nitrosophenyl product takes plac...

1.As a background for studies of the action mechanisms of biological alkylating agents a number of methanesulfonic esters were investigated with respect to rates of hydrolysis and reaction with different nucleophiles, mostly at 20°, 25° and 37°.2.The reaction patterns of monofunctional alkyla...

Synthesis of trihydroxylated pyrrolizidines, the enantiomer of 2-epihyacinthacine A2 and indolizidine analogues of the natural alkaloids is reported. The key step of these syntheses is the stereoselective samarium diodide-induced coupling of the chiral nitrone prepared from d-ribose with methyl ...

6-Ethoxycarbonyl-5-hydroxy-benzo[a]carbazoles were prepared from ethyl 3-(1-methyl-1H-indol-3-yl)-3-oxopropanoates in two steps: the first step involved α-arylation of the indicated starting materials via Ullmann–Hurtley reaction; in the key second step, the thus formed coupling products under...

Phosphorescence from the triplet probe erythrosin B provides spectroscopic characteristics such as emission energy and lifetime that are specifically sensitive to molecular mobility of the local environment. This study used phosphorescence of erythrosin B to investigate how variation in NaCl con...

A thin film dissolved oxygen sensor was fabricated by trapping erythrosin B in a sol–gel matrix. No phosphorescence was observed when the sensor was immersed in water. Very weak phosphorescence was observed when erythrosin B was dissolved in aqueous ethanol and acetone solutions. However, fluor...

Herein, an amorphous MoS3 sample suitable for cost-effective and large-scale photocatalytic hydrogen production was prepared via a very simple and practicable wet chemistry method. Using Erythrosin B (EB) as sensitizer, the obtained MoS3 exhibits much higher hydrogen evolution performance (1190....

Erythrosin B (EB) binding to proteins causes a decrease in the fluorescence maximum of EB at 550 nm. Based on this, a new, fast and simple fluorescence quenching method for the determination of proteins is developed. The linear range of this assay is 1.36–20.4 μg ml−1. The method has very few ...

BackgroundIn spite of the urgent necessity for a screening test of urinary protein for the early diagnosis of kidney diseases, a rapid, accurate and cost-effective method for their detection has yet to be developed.

Cu-Cu2O nanoparticles (NPs) decorated porous graphitic carbon nitride (g-C3N4) (Cu-Cu2O/g-C3N4) photocatalysts were prepared. When investment of copper source materials in the experiment increased to 7 wt%, the highest H2 evolution rate (400 μmol g−1 h−1) was obtained under visible light irradi...

Erythrosin B (EB) sensitized graphitic carbon nitride (g-C3N4) for photocatalytic hydrogen evolution was investigated using triethanolamine (TEOA) as an electron donor under visible light irradiation (λ > 420 nm). MoSx was loaded on g-C3N4 as a cocatalyst by an in situ photoreduction method dur...