2-Bromoethyl glycosides can easily and in high yields be transformed into sulfones by treatment with a suitable thiol followed by oxidation with mCPBA. The observation that the so formed sulfones were cleaved by treatment with NaOMe/MeOH was used to design a new safety catch linker for synthesis...

Substantial effort has been devoted toward understanding the psychopharmacological effects of tryptamine hallucinogens, which are thought to be mediated by activation of 5-HT2A and 5-HT1A receptors. Recently, several psychoactive tryptamines based on the N,N-diallyltryptamine (DALT) scaffold hav...

Carbocyclic inosine is a potent inhibitor for the growth of the promastigote form of Leishmania tropica and Leishmania donovani. In culture, the EC50 values of carbocyclic inosine are 8.3 × 10−8 and 1.3 × 10−7M for the promastigotes of L. tropica and L. donovani, respectively. On the other han...

The effect of (+)-sotalol and deoxysotalol on prostaglandin (PGF2a and 15-methyl PGF2α)-evoked contractions was studied using the isolated rat uterus. After control responses to prostaglandins had been obtained the uterus was exposed to the nutrient fluid containing 10 μg/ml of (+)-sotalol, de...

Here we present the preparation of 14 pairs of cis- and trans-diammine monochlorido platinum(II) complexes, coordinated to heterocycles (i.e., imidazole, 2-methylimidazole and pyrazole) and linked to various acylhydrazones, which were designed as potential inhibitors of the selenium-dependent en...

Hydroxy aluminium octacarboxy phthalocyanine (Al(OH)OCPc) was conjugated with a diammine platinum complex to give conjugates containing two or three platinum complexes (represented as: Al(OH)OCPc(Pt)2 and Al(OH)OCPc(Pt)3). It was found that the complexes were soluble in water at a pH > 8.2. Both...

Silver nanoparticles (∼30–70 nm) have been impregnated on the activated graphite powder by an electroless plating method. The so prepared silver decorated graphite powders are characterized by field emission scanning electron microscopy, powder X-ray diffraction, energy dispersive X-ray and X-...

The adsorption of silver diammine complexes on carbon surfaces has been investigated. Well-characterized carbon supports with known active surface area have been used. The silver complex is adsorbed on edge carbon sites which are part of the active surface area. Once adsorbed the complex decompo...

ObjectivesTo investigate the effectiveness of silver diammine fluoride (SDF) solution application in arresting dental root caries and to assess the color of arrested caries lesions.

To determine whether the method of “strong electrostatic adsorption” (SEA) can be extended to the preparation of uniform and highly dispersed supported Ag catalysts, the adsorption of silver diammine, Ag(NH3)2+, also known as Tollen’s reagent, has been examined over five supports (i.e., SiO2,...

ObjectivesThe objective of this study was to investigate the effect on the microtensile bond strength of a glass-ionomer cement (GIC), which is used for Atraumatic Restorative Treatment (ART), to normal and artificial carious dentine surface that had been treated with silver diammine fluoride (S...

In this study, a bio-electrochemical system was used to investigate the recovery of silver from diammine complex [Ag(NH3)2]+, coupled with power generation and wastewater treatment, measured in terms of chemical oxygen demand (COD) removal. Acetate was oxidized by anodic microorganisms to produc...

The crystal and molecular structures of three bis(phosphine) copper(I) tetrahydroborate complexes have been determined at 125 K. Bis(tricyclohexylphosphine) copper(I) tetrahydroborate, (Cy3P)2Cu(BH4) (1), bis(tri-p-tolylphosphine) copper(I) tetrahydroborate, (p-tolyl3P)2Cu(BH4) (2) and bis(tri-p...

The synthesis and characterization of (TptBu,Me)Yb(BH4)(THF)n (n = 0, 3; n = 1, 4) complexes are reported. The compounds represent rare examples of lanthanide (II) tetrahydroborate complexes. The X-ray crystal structure of complex 4 has been determined and it shows a monomeric, formally seven co...

The tetrahydroborates represent a class of complex hydrides with the largest gravimetric and volumetric hydrogen density for hydrogen. Therefore, these compounds are potential hydrogen storage materials for mobile applications. The alkali metal and alkali earth metal tetrahydroborates have been ...

A highly efficient two-step regio and stereoselective method for the synthesis of both cis-vinyltrimethylstannanes and cis-vinylpinacolboronates is described. This method takes advantage of the known lithium/tellurium exchange pathway providing a versatile alternative to known literature methods...

The efficient and expeditious syntheses of both enantiomers of the amphibian alkaloid cis-225H have been achieved. Utilizing a common cis-2,5-disubstituted pyrrolidine building block derived from (+)-2-tropinone, the enantioselective syntheses have established the absolute configuration of these...

The Raman spectra of several pairs of alkenyl methyl ethers of general structure R1R2CCR5C(R3R4)OCH3 and R1R2C(OCH3)C(R5)CR3R4 (R1, R2, R3, R4, R5 = H or CnH2n+1, n = 1–3) are reported and discussed, with a view to establishing whether Raman spectroscopy offers a viable means of distinguishing ...

4-Pentenoxyl radicals cyclize 2,3-cis-selectively, when substituted by an allylic hydroxy, acetyloxy, or benzoyloxy group. Additional substituents increase or decrease the fraction of 2,3-cis-cyclized product, depending on relative configuration, positioning, and their chemical nature. The prefe...

The adsorption ratio of isobutane/1-butene on the catalyst surface is one of the most important factors for the C4 alkylation process. Regulation of isobutane/1-butene adsorption ratio on the zeolite-supported acid catalyst is a big challenge for catalyst preparation. To regulate the isobutane/1...