The unique interconnected mesoporous structure and high specific surface area facilitate the diffusion and absorption of Na+, making ordered mesoporous carbon a promising candidate for the anode of sodium-ion batteries. However, low electronic conductivity and scanty defects cause unsatisfied so...

Pantoprazole sodium, a substituted benzimidazole derivative, is an irreversible proton pump inhibitor which is primarily used for the treatment of duodenal ulcers, gastric ulcers, and gastroesophageal reflux disease (GERD). The monographs of European Pharmacopoeia (Ph. Eur.) and United States Ph...

A novel transformation of 7-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-4-chromanone (1) to intramolecular 1,3-arene-alkene photocycloadduct, (1S,2R,5S,7S,10S,13R)6,6,10-trimethyl-14-oxapentacyclo[8.3.1.01,7.02,1305,13] tetradecane-3,12-dione (3) via secondary photorearrangement of 1,2-arene-alkene...

Two new triterpene glycosides isolated from the root bark Guettarda angelica were proven to be quinovic acid-3β-O-[β-d-glucopyranosyl-(1 → 3)-α-l-rhamnopyranoside] and quinovic acid-3β-O-β-d-glucopyranosyl-(28 → 1)-β-d-glucopyranosyl ester. In addition quinovic acid and two known glycosi...

Samples from the Turin Shroud (TS) furnished by STERA Inc. have been analyzed and compared with both material coming from the TS and sticky tapes taken from a copy of the TS produced in 1656 and conserved at Palma di Montechiaro, Sicily, Italy. The attention has been focalized to the many reddis...

Evaluation of analogs of the blocked insect myotropic neuropeptide leucopyrokinin (LPK) has demonstrated its relative insensitivity to amino acid substitution in the N-terminal in contrast to the C-terminal region. Truncated analogs of LPK without the first, second, and third N-terminal amino ac...

An insect neuropeptide leucopyrokinin (LPK) (pQTSFTPRLamide) accelerates pupariation in wandering larvae of the fleshfly Sarcophaga bullata. The period of sensitivity to the action of LPK begins approximately 4 h before pupariation. Within this period the degree of acceleration of contraction in...

The antinociceptive effect of intracerebroventricular injections of [2–8]-leucopyrokinin (LPK), a truncated leucopyrokinin analogue, was determined in rats, by means of a tail immersion test. We found a significant antinociceptive effect of three i.c.v. doses of [2–8]-LPK: 1, 5 and 10 nmol. Pr...

Initial responses and adaptation of the porcine pituitary-adrenal axis to a chronic intermittent stressor (45-min daily restraint for 8 or 9 d) and effects of this stressor on binding to adrenocortical ACTH receptors were measured. Blood samples were obtained via indwelling jugular catheters on ...

GnRH has several direct actions on rat granulosa cells. Specific receptors for GnRH have been demonstrated on rat and human ovaries. Whether the porcine ovary has specific receptors for GnRH is still debated and the physiological actions of GnRH on porcine granulosa cells have not yet been clari...

It has been proved that TRAM-Derived Decoy peptides have anti-inflammatory properties. In this study, we synthesized a TRAM-Derived decoy peptide (TM6), belongs to TRAM TIR domain, of which sequence is “N”-RQIKIWFQNRRMKWK, KENFLRDTWCNFQFY-“C” and evaluated the effects of TM6 on lipopolysacch...

TRAM/TICAM-2 is used by Toll-like receptor 4 (TLR4) as a bridging adaptor during the mammalian innate immune response. It recruits TRIF, another TIR domain-containing adaptor protein, to TLR4 via TIR domain interactions, which leads to the activation of transcription factors responsible for the ...

Conjugative transfer plays a major role in the transmission of antibiotic resistance in bacteria. pIP501 is a Gram-positive conjugative model plasmid with the broadest transfer host-range known so far and is frequently found in Enterococcus faecalis and Enterococcus faecium clinical isolates. Th...

The translocating chain-associating membrane protein (TRAM) is a glycoprotein involved in the translocation of secreted proteins into the endoplasmic reticulum (ER) lumen and in the insertion of integral membrane proteins into the lipid bilayer. As a major step toward elucidating the structure o...

The conjugative transfer of bacterial F plasmids relies on TraM, a plasmid-encoded protein that recognizes multiple DNA sites to recruit the plasmid to the conjugative pore. In spite of the high degree of amino acid sequence conservation between TraM proteins, many of these proteins have markedl...

The polyphenols and phaseolin interaction in common bean varieties was studied. Raw beans of three different colours were analysed: black (BRS Supremo), brown (BRS Pontal) and white (WAF-75). Based on the phaseolin digestibility in vitro and phaseolin–polyphenol complexation obtained by SDS–PA...

Monoclonal antibodies A5 and C6 have been reported previously to recognize developmentally regulated determinants involving N-acetyllactosamine [Fenderson B.A., O'Brien D.A., Millette C.F. and Eddy E.M. (1984) Devl Biol. 103, 117–128]. In the present study, the specificity of these antibod...

Coastal water clarity varies at high temporal and spatial scales due to weather, climate, and human activity along coastlines. Systematic observations are crucial to assessing the impact of water clarity change on aquatic habitats. In this study, Secchi disk depths (ZSD) from Boston Harbor, Buzz...

BackgroundRecommendations aimed at reducing infants’ risk for rapid weight gain primarily focus on promoting caregivers’ use of responsive feeding practices and styles. These recommendations are grounded in the belief that infants will effectively signal hunger and satiation to their caregiver...

ObjectivesStatistical methods to adjust for treatment switching are commonly applied to randomized controlled trials (RCTs) in oncology. Nevertheless, RCTs with extension studies incorporating nonrandomized dropout require consideration of alternative adjustment methods. The current study used a...