Several cholesteryl naphthalimide-derived compounds have been sythesized and developed as CO2 sensors. The derivatives, incorporating ether chains, were found to be capable of gelating various organic solvents, due to the modulation of the hydrophilicity/hydrophobility properties of them. The re...
Electrochemical cholesterylation of various sugars with cholesteryl diphenylphosphate was studied. The reaction afforded mono-, di-, tri-, and tetra-cholesterylated products using equivalent amounts of the reagent. The reactions turned out to be completely stereoselective with respect to both su...
In previous studies, retinyl palmitate hydrolase activity in rat liver was partly characterized and was found to correlate and to partially copurify with hydrolytic activities against Cholesteryl oleate and triolein. The present studies were designed to further explore relationships between thes...
A pair of first and second generation poly(alkyl ether imine) dendrimers is prepared, having covalently attached cholesteryl moieties at their peripheries. The pairs in each generation differ in the alkyl-linker which constitute the dendritic core moieties, even when the number of cholesteryl mo...
The aim of this work is to obtain Sn-doped MAO coatings with yellow color on magnesium alloy in a new sodium stannate (Na2SnO3) electrolyte system, which is different from traditional micro arc oxidation (MAO) colored-coating with transition metal salt addition. The formation mechanism, microstr...
Dispersants are used to remove oils slicks from sea surfaces and to generate small oil-droplet dispersions, which may result in enhanced biodegradation of the oil. In this study, dispersibility and biodegradation of chemically dispersed oils with different physical-chemical properties (paraffini...
Extensive attention has been focused on the development of rare-earth-free phosphors, due to their low cost, good absorption and emission properties. However, the yellow light emitted phosphors with good quantum yield and thermal stability are still urgent. Herein, we successfully prepare the si...
Attapulgite/bismuth yellow hybrid pigments were successfully fabricated by sol-gel method followed by a calcining process. The color of the hybrid pigments was superior to BiVO4 samples after incorporating of the “magic wand” of attapulgite, and this strategy was also in favor of controlling t...
Extraction of disperse yellow 54 with supercritical carbon dioxide was conducted at 393.2 K and 30 MPa over a wide range of contact times. Saturated solubilities of the disperse dyestuff in supercritical carbon dioxide with or without cosolvent were also measured over the temperature and pressur...
It is still a challenge to disperse yellow iron oxides in organic media due to their susceptible aggregation, which limits their application in ceramic material area. In order to achieve colloidal stabilization in organic liquid, yellow iron oxides were dispersed in ethanol with p[methyl methacr...
The southwestern South Yellow Sea (SYS) is influenced by tremendous sediment loads derived from the Yellow River (Huanghe) and the Yangtze River (Changjiang). However, the influence of Yangtze River sediments and their transport mechanism in this area remain unresolved. In this study, we present...
BackgroundYellow Dust (YD) is a natural source of particulate matter (PM) in Korea. It remarkably increases the concentration of PM. However, characteristics of PM in YD period are different from those of PM in non-YD period.
Condensation reactions of dialdehydes and naphthols have been carried out and the structures of the products have been investigated. Naphthofuronaphthofuran type compounds have been obtained in the case of using glyoxal and 2-naphthol or dihydroxynaphthalenes. Malonaldehyde and glutaraldehyde ha...
Dibromodulcitol (DBD), labelled with [3−H] at position C-1, was administered orally to 6 patients in a single dose of 15 mg/kg. Kinetic parameters were calculated for the effective drug (DBD + BrEpG + DAG), protein-bound hexitol moieties and free metabolites. Approximate values were estimated fo...
The effect of dibromodulcitol (DBD) on the incorporation of labelled precursors into DNA and RNA fractions of PHA-stimulated human lymphocytes and of P388F lymphoma cells at various stages of their growth was studied. Both cell systems showed sensitivity to the drug within the concentration rang...
The bromine content of human gliomas and white matter was determined by neutron activation analysis (NAA) following p.o. administration of a single dose of 400–500 mg/m2 dibromodulcitol (DBD). In another group of patients with brain gliomas, the bromine content was measured subsequent to applic...
A combination of dibromodulcitol 500 mg orally, mitomycin C 10 mg i.v. and vinblastine 10 mg i.v. all given on day 1 and repeated every 4 weeks was given to 40 patients with advanced breast cancer. All but one had received previous endocrine therapy. The response rate (CR + PR) in 24 previously ...
A-431 squamous cell carcinoma cells were treated in vitro with either 4 Gy radiatio of 15 (or 45) μg/ml dibromodulcitol (DBD), as well as with combined 4 Gy irradiation and DBD, with the latter as either a pretreatment or post-treatment. DBD alone or in combination with radiation had a greater ...
SummaryThis article has surveyed the current status of dibromodulcitol with respect to chemistry, mechanism of action, animal and human pharmacology and experimental and clinical antitumor activity. The following conclusions may be drawn:(1)As an alpha, omega dibrominated hexitol, DBD shares man...
The rate and extent of dibromodulcitol (DBD) conversion by 9000 g rat liver supernatant with an NADPH-generating system (S-9 mix) were studied using 3H-labelled drug. Results indicated that S-9 mix seemed to exert an initial protective effect delaying the solvolysis of DBD for about 30 min at 37...
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