Significant metabolism of 5α-androstane-3β,17β-diol to 17β-hydroxy-5α-androstan-3-one was recorded in several tissues and organs from rats and humans. This bioconversion was further investigated in rat testis homogenates. 5α-Androstane-3β,17β-diol was readily metabolized to 17β-hydroxy-...

Mass spectrometric identification and characterization of steroids using electrospray ionization and tandem mass spectrometry has advantages in drug testing and doping control analysis attributable to limitations of gas chromatography followed by electron ionization mass spectrometry. Steroids w...

Infrared spectroscopy studies of 17β-hydroxy-17-methyl-2-oxa-5α-androstan-3-one (HMOA) in 20 different pure organic solvents were undertaken to investigate the solute–solvent interactions and to correlate solvent properties, such as the KBM equation, the solvent acceptor number (AN), Schleyer...

The catalytic behavior of insoluble polyorganosiloxane gels containing amino groups or phosphonium salts was examined in the reaction of oxiranes with S-phenyl thioacetate. The catalysts, poly(p-chloromethyl)phenylsiloxanes containing phosphonium salts, have high catalytic activity and the obser...

Microbial infection remains one of the most serious complications associated with the use of indwelling medical devices.Antimicrobial agents are those materials capable of killing pathogenic microorganisms. In general, they are low molecular weight compounds. However, most of these molecules are...

Two mutually reactive two-component copolymers were prepared to use as humidity-sensitive membranes. The major component of humid membrane is cross-linked polyelectrolyte prepared from cross-linked copolymers of 4-vinylpyridine (VP)/vinylbenzyl tributyl phosphonium chloride (VTBPC): 3/1, 4/1 and...

Several simple, lightly cross-linked quaternary phosphonium- and ammonium-based polymer coatings were found to effectively resist the non-specific adsorption of proteins (i.e., bovine serum albumin (BSA) and fibrinogen (Fg)) from aqueous solution under both static exposure and dynamic membrane f...

New phosphonium salt-containing monomer, (vinylbenzyl)tributyl-phosphonium chloride (VTBPC) was prepared and polymerized for humidity-sensitive polyelectrolyte. The humidity-sensitive membranes were composed of cross-linked copolymers with different contents of VTBPC, n-butyl acrylate (n-BA) and...

Synergistic effects of synthetic phosphonium sulfonates (PhSs) bearing different groups with expandable graphite (EG) on flame retardancy properties in poly(ethylene-co-vinyl acetate) (EVA) rubber blends have been studied by limiting oxygen index (LOI), UL-94 test, cone calorimeter test (CCT), a...

Sodium montmorillonite (MMT) was modified with several organic phosphonium salts. Organoclays with water soluble surfactants were prepared by the traditional cation exchange reaction. An alternative procedure was used to prepare organoclays with water insoluble salts. The effect of chemical comp...

Room-temperature ionic liquids (ILs) have been shown to be successful as stationary phases (SPs) for gas chromatography in several fields of applications because of their unique and tunable selectivity, low vapor pressure and volatility, high thermal stability (over 300 °C), and good chromatogr...

After studying three polymorphs for clofexamide hydrochloride we have established the phase diagram of the binary system clofexamide hydrochloride(I)-phenylbutazone(I) by different methods: differential scanning calorimetry, differential thermal analysis, transparency method and thermomicroscopy...

Hydrogen sulfide has important biomedical significance because it plays a regulatory role in a variety of physiological processes. In our previous work, we investigated the effect of substituents on Stokes shift of BODIPY and found that methoxy groups on phenyl substituents at 3,5-positions coul...

4-Nitrophenyl[bis(benzylthio)]methane was synthesized and used in structural study by X-ray diffraction combined with NMR and spectrophotometric method. In the crystal structure the molecule assumes the conformation where the acidic H-atom is difficult to access due to sterical hindrances of thr...

An efficient and convenient Meglumine catalyzed procedure for the synthesis of bis(indolyl) methanes at ambient temperature under aqueous conditions in high yields. The catalytic reaction proceeds very smoothly. Clean reaction, ease of product isolation/purification, easily available reactants, ...

New poly(1,3,4-oxadiazole-imide)s containing dimethylsilane units have been prepared by solution polycondensation reaction of an aromatic dianhydride incorporating dimethylsilane group, namely bis(3,4-dicarboxyphenyl)dimethylsilane dianhydride, with different aromatic diamines having preformed 1...

The (E) and (Z) isomers of α bromo 2 hydroxy-4-nitrochalcone both exhibited the unusual ability to undergo nucleophilic addition to the α position of the double bond. They differed markedly, however, in their preferred mode, the former favoured α addition, the latter β addition. It is propos...

A potentially useful second harmonic generation (SHG) organic material, 4-OCH3-4′-nitrochalcone (MNC), has been synthesized and grown as a high-quality single crystal by the slow evaporation technique. The grown crystals were characterized by FT-IR, single-crystal X-ray diffraction (XRD), therm...

A series containing twelve substituted styryl 4′-nitrophenyl ketones have been synthesized using solvent free SiO2–H2SO4 catalysed aldol reaction under microwave condition. The yield of chalcones is found to be more than 80%. These synthesized ketones have been characterized by their physical ...

An efficient method for construction of 3-arylquinolin-4(1H)-ones via in situ Meinwald rearrangement/intramolecular reductive cyclization of 2′-nitrochalcone epoxides has been developed. The practical approach is of excellent functional groups compatibility with as high as 98% yield under mild ...