For biomedical applications, chitosan and oligochitosan must be appropriately characterized and meet pharmacological requirements in terms of contamination by residual heavy metals.In this work, a series of commercial chitosans was analyzed by ICP-MS method, and high concentration of Fe (44–382...

The synthesis of a series of 4-[1-(substituted phenyl)-2-oxo-pyrrolidin-4-yl]methyloxybenzoic acids and related compounds, and their evaluation for inhibitory capacity toward fatty-acid and sterol biosyntheses using rats' liver slices in vitro and rabbits in vivo, are described. Among the c...

A novel series of 3-(1-(1-substituted piperidin-4-yl)-1H-1,2,3-triazol-4-yl)-5-substituted phenyl-1,2,4-oxadiazoles bearing 1,2,3-triazole and piperidine ring has been synthesized in one step from amidoxime using Carbonyl diimidazole (CDI) and K2CO3. All the synthesized compounds (4a–4r) are no...

Eight different Dichloro(bis{2-[1-(4-R-phenyl)-1H-1,2,3-triazol-4-yl-κN3]pyridine-κN})iron(II) compounds, 2–9, have been synthesised and characterised, where group R = CH3 (L2), OCH3 (L3), COOH (L4), F (L5), Cl (L6), CN (L7), H (L8) and CF3 (L9). The single crystal X-ray structure was determi...

The Raman spectra (50–1200 cm−1) of gaseous, liquid, and solid (Cl3Si)2O have been recorded. The infrared spectra of the gas and solid have been recorded from 55–2000 cm−1 . The spectra of the gas have been interpreted in detail on the basis of C2v symmetry with the A1 skeletal Si-O-Si bend as...

The IR spectra of hexachlorodisiloxane, (SiCl3)2O, in argon, krypton and nitrogen matrices have been investigated in the region from 1500–200 cm−1. The data in all three of the matrices are unusual in that the antisymmetric Si-O-Si stretch is a doublet. The maximum separation of the doublet is ...

The infrared and Raman spectra of hexachlorodisiloxane indicate a nonlinear Si-O-Si linkage, and the results are analyzed in terms of a bent C2vv, model. Earlier results are shown to be in error because of misassignments or because samples had been contaminated with impurities. In the present wo...

The vibrational spectrum of hexachlorodisiloxane has been re-examined using more accurate depolarization ratio data than was available earlier. The molecular skeleton is shown to be bent and vibrational assignments are discussed.

Several complexes with tosylamides were synthesised by the electrochemical oxidation of cobalt in an acetonitrile solution of [(4-methylphenyl)sulfonyl]-imino-1H-pyridine (HL) and the appropriate neutral coligand: L′ (pyridine, 2,2′-bipyridine, 1,10-phenanthroline or N,N-dimethylformamide). Th...

The molecular structural parameters, thermodynamic properties and vibrational frequencies of the fundamental modes of 2,2-dichloro-N-(2,3-dichlorophenyl) acetamide (2,3CPA) and 2,2-dichloro-N-(2,4-dichlorophenyl) acetamide (2,4CPA) have been obtained using density functional theory (DFT) techniq...

8-Bromo-N6-phenoxyacetyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine-3′-O-(2-cyanoethyl-N,N-diisopropyl) phosphoramidite was synthesized and used to introduce 8-bromo-2′-deoxyadenosine (8-Br-dA) into oligodeoxynucleotides by means of automated synthesis. 8-Br-dA was found not to affect ad...

Commercial riboflavin production with Bacillus subtilis has been developed by combining rational and classical strain development for almost two decades, but how an improved riboflavin producer can be created rationally is still not completely understood. In this study, we demonstrate the combin...

Commercially available preparations of flavin adenine dinucleotide (FAD) have been found to be 94% pure, the remaining 6% being composed of four or five minor contaminants which can be separated from FAD by reverse-phase high-performance liquid chromatography. FAD purified in this manner has bee...

The blockage of the de novo pyrimidine biosynthetic pathway at the orotidine-5′-phosphate decarboxylase level was previously demonstrated to affect riboflavin production in the industrial producer fungus Ashbya gossypii. However, the molecular basis for the unusual sensitivity to uracil display...

The addition of Lewis acids changes the path of the reaction of N-vinylpyrroles with 3,4-dihydroisoquinoline-N-oxides: formal (3 + 3)-cycloaddition proceeds instead of (3 + 2)-cycloaddition. In the case of benzoyl(3,4-dihydroisoquinolin-2-ium-2-yl)amides, reaction path does not change in the sam...

We study the decomposition as an SO(3)-module of the multiplicity space corresponding to the branching from SO(n+3) to SO(n). Here, SO(n) (resp. SO(3)) is considered embedded in SO(n+3) in the upper left-hand block (resp. lower right-hand block). We show that when the highest weight of the irred...

An efficient algorithm for enumerating representations of U(3) that occur in a representation of the unitary group U(N) is introduced. The algorithm is applicable to U(N) representations associated with a system of identical fermions (protons, neutrons, electrons, etc.) distributed among the N=(...

N-3 fatty acids, including docosahexaenoic acid (DHA), have a beneficial effect in both pain and psychiatric disorders. In fact, we previously reported that stress-induced pain prolongation might be mediated through the suppression of the G-protein coupled-receptor 40/free fatty acid receptor 1 ...

Optical spectral studies of Tm(III) ion in nitrate, sulphate, and acetate solutions of thulium, ammonium, magnesium, potassium and sodium have been made. Second derivative spectra recorded for the first time revealed interesting results in all the fifteen samples studied. Lifetimes of the laser ...

In this work thermoluminescent properties of α-Al2O3 samples doped with Tb3+ and Tm3+, prepared by the combustion synthesis route, were studied. Samples were prepared by mixing stoichiometric amounts of aluminum nitrate, urea and dopants with different amounts of terbium and thulium nitrates va...