Lignin is one of the most abundant by-products of pulp and paper manufacturing and second-generation biorefineries. Presently it is mainly used for energy production, but it is evident that higher added-value utilization options would be beneficial. One possible process is to use lignin as build...

A leveler containing quaternary ammonium cations, namely poly (1-vinyl imidazole co 1, 4-butanediol diglycidyl ether) (VIBDGE) was synthesized and studied in this work. Quantum chemical calculations and molecular dynamics simulation of VIBDGE were employed to get insight to the adsorption model ...

We investigated the broadband terahertz spectra (0.1–5.0 THz) of glass-forming liquids, propylene glycol (PG), its oligomers poly (propylene glycol)s (PPGs), and poly (propylene glycol) diglycidyl ether (PPG-de) using broadband terahertz time-domain spectroscopy and low-frequency Raman scatteri...

Cationic photopolymerization studies of poly(propylene glycol)diglycidyl ether with and without 25 wt% of resorcinol diglycidyl ether were carried out in presence of bis(4-methylphenyl)iodonium hexafluorophosphate as photoinitiator. Analyses were carried out using polychromatic radiation at diff...

Our aim was to discover RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors that possess strong activity and sufficient oral absorption, and thus, we selected a 5-amino-linked thiazolo[5,4-d]pyrimidine derivative as the lead compound because of its potential kinase inhibitory a...

Neurofibrillary tangles (NFTs) composed of hyperphosphorylated and aggregated tau are common pathological characteristics in Alzheimer's disease (AD) and other tauopathies. Aberrant tau phosphorylation is an early and pivotal event in the pathogenesis of tauopathies, and since GSK-3 is a ke...

SummaryBoth enantiomers of 2-(dimethylamino)-1-[3-methoxy-2-(1-methylethoxy)phenyl)ethanol were synthetized by a stereoselective route and evaluated in vitro for their uroselectivity in comparison with other α1-adrenoceptor agonists. The most potent enantiomer was structurally characterized by ...

Two new Co(II) coordination polymer, namely [Co2(L)2(H2O)]n (1) and [Co(L)(phen)(H2O)]n·xH2O (2) (H2L = 5-(benzyloxy)isophthalic acid, phen = 1,10-phenanthroline) have been hydrothermally synthesized and characterized by elemental analysis, powder X-ray diffraction, thermal analysis and single ...

Ortho-thymotic acid and nine homologs were submitted for general, analgesic, and antistress evaluations in the rat. While all appeared to be nonspecific central nervous system depressants, only 2-methyl-5-tert-butylsalicylic acid appeared to have significant analgesic ability in the rat tail fli...

The constant volume energy of combustion of crystalline 3,5-di-tert-butylsalicylic acid (t-BSA) in oxygen at 298.15 K was determined using combustion calorimeter to be −8292.57±2.51 kJ mol−1. The standard molar enthalpies of combustion and formation of 3,5-di-tert-butylsalicylic acid were deriv...

The ground state electronic structure of boron, zinc and aluminum complexes of 3,5-di-tert-butylsalicylic acid (t-BSA) was studied by fluorescence spectroscopy. These compounds are negative charge control additives (CCAs) commercially known as LR120, Bontron E84 and Bontron E88 respectively. The...

Microwave assisted solid-state reaction between equimolar quantities of sterically encumbered 3,5-di-tert-butylsalicylic acid (H2-DTBSA) and n-butylstannoic acid results in the formation of hexameric drum shaped stannoxane [nBuSn(O)(H-DTBSA)]6 (1). Synthesis of 1 could not be achieved under norm...

Alkaline earth metal trichloroacetates M(O2CCCl3)2·nH2O where M = Be (1), n = 4; M = Mg (2), n = 6; M = Ca (3) or Sr (4) or Ba (5), n = 4 were synthesized by reacting BeSO4 with hydrated barium trichloroacetate for 1 and neutralization of respective metal carbonates with trichloroacetic acid fo...

Discrete Zn(II) and Cu(II) complexes have been synthesized by using N-hydroxy-N,N′-diarylformamidine ligands: N-hydroxy-N,N′-bis(2,6-diisopropylphenyl)formamidine (L1), N-hydroxy-N,N′-bis(2,6-dimethyl)formamidine (L2), N-hydroxy-N-(2-methoxyphenyl)-N′-(2,6-diisopropylphenyl)formamidine (L3),...

An intriguing selectivity towards the formation of the formamidine was observed upon the reaction of an amine with sodium hydride and trifluoroacetic anhydride in dimethyl formamide. Various aromatic amines were reacted with a series of N,N-disubstituted formamides as a solvent under the influen...

Tyrosinase (EC 1.14.18.1) is the key enzyme of most food enzymatic oxidation. Tyrosinase inhibitors are important in food industry. In the present paper, 2-chlorcinnamic acid and 2,4-dichlorocinnamic acid were synthesized and the inhibitory kinetics on mushroom tyrosinase were investigated. The ...

The solid-state structures of the previously known para-substituted diphenyltellurium dichlorides, (p-XC6H4)2TeCl2 (X=H (1), Me (2), MeO (3)) were investigated by 125Te MAS NMR spectroscopy and in case of 2 by single crystal X-ray diffraction. The 125Te-NMR shielding anisotropy (SA) was studied ...

N,N-Alkyl monothiocarbamate derivatives of diphenyltellurium, Ph2Te[SCONR2]2 and Ph2TeCl[SCONR2], where NR=NEt2, NCH2(CH2)2CH2, and NCH2(CH2)3CH2, were obtained by the reaction of NaSCONR2 with Ph2TeCl2 and characterized by vibrational, 1H and 13C NMR spectroscopy. Molecular structures were dete...

The design of mixed-ligand complexes are of increasing interest from fundamental as well as technological and curative aspects. Having that in mind, we studied zinc complex containing 2,2′-dipyridylamine (dipya) and dianion of isophthalic acid (ipht), [Zn(dipya)(ipht)]n, as promising precursor ...

The synthesis of four cationic mixed–ligand Ni(II) complexes with 2,2′–dipyridylamine (dpamH) and substituted salicylaldehydes (X–saloH) was undertaken in an effort to discover new biologically active compounds. The complexes with the general formula [Ni(dpamH)2(X–salo)]Cl, 3–6, namely [Ni...