A facile surface-enhanced Raman scattering (SERS) substrate based on the self-assembly of silver nanoparticles on the modified silicon wafer was obtained, and for the first time, an advanced SERS analysis method basing on this as-prepared substrate was established for high sensitive and rapid de...

The fresh [email protected] Zeolite Imidazolate Framework-8 ([email protected]) was exploited as an prospective adsorbent for the removal and abruption of U(VI) ions from aqueous solutions for the first time. The material exhibited a latent adsorption capacity of 277.77 mg g−1 and an eminent sel...

The speciation of uranium(VI) extracted by a molecular extractant N,N,N′,N′-tetra(n-octyl)diglycolamide (TODGA) and a hydrophobic ionic liquid (IL), namely 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide [C4mim][Tf2N], mixture from acidic nitrate media in 1,2-dichloroethane (DCE...

In the framework of spent nuclear fuel reprocessing, N,N‑dialkylamides are molecules of interest for the selective recovery of uranium and plutonium. Two monoamides, DEHBA (N,N‑di‑2‑ethylhexyl‑butyramide) and MOEHA (N,N‑methyl, octyl‑2‑ethylhexanamide), were investigated to evaluate the effect o...

The solubility of uranyl nitrate hexahydrate was determined as a function of nitric acid concentration and temperature, and the crystallization yield was calculated. Results showed an increase in crystal formation at lower initial nitric acid concentrations upon cooling a saturated solution of U...

The conformations of drugs and receptors play a very important role in determining their biological properties. In order to understand the role of the conformation of β-adrenergic blocking agents, perturbative configuration interaction using localized orbitals (PCILO) computations were done on ...

BackgroundBuame [17β-(butylamino)-1,3,5(10)-estratrien-3-ol] possesses anticoagulant and antiplatelet activities that are potentially antithrombotic. Since its estrogenicity is unknown, it was evaluated by established methods.

The chiral synthesis of β-blockers such as (S)-timolol requires a sensitive analytical method for the enantioseparation of its intermediate, 3-tert.-butylamino-1,2-propanediol, in the ng/ml range. The method developed is based on on-line normal-phase LC–MS–MS using a chiral stationary phase a...

Topoisomerase II poison blocks the transitorily generated DNA double-strand breaks (DSBs) from religation, thereby causes severe DNA damage and gene toxicity. While topoisomerase II catalytic inhibitor does not form cleavable DNA-enzyme complex because its function attributes to inhibition of th...

Four new n-butylamino and two sulfur-containing derivatives of polyfluoro-1,4-naphthoquinone were synthesized and their mutagenic and antioxidant properties in Salmonella cells, as well as the cytotoxicity in human myeloma (RPMI 8226), human mammary adenocarcinoma (MCF-7), mouse fibroblasts (LMT...

The present study reports the synthesis and characterization of 2,2'-(diazene-1,2-diylbis(4,1-phenylene))bis(6-(butylamino)-1H-benzo[de]isoquinoline-1,3(2 H)-dione) (4) using a dual approach consisting of experimental and computational techniques. The indigenously synthesized compound 4 is ...

A method for the separation and quantitation of the enantiomers of 3-tert.-butylamino-1,2-propanediol by high-performance liquid chromatography and evaporative light scattering detection has been developed. Separation of the enantiomers was performed in normal-phase liquid chromatography on a Ch...

Proton/carbon-13 chemical correlations were determined for four trans-trimedlure isomers whose eight cyclohexyl protons, detected as a complex pattern in the region of 1.50–2.60 ppm, had not been previously assigned or correlated. The effects of axial and equatorial chloro substitution in the 4...

The conformation of 1,1-dimethylethyl 5-chloro-cis-2-methylcyclohexane-1-carboxylate (trimedlure-Y) was confirmed as 1,2,5 equatorial, axial, equatorial via 13C, 1H, APT, CSCM and COSY NMR analyses. The carbon and proton nuclei in trimedlure-Y and the previously unassigned eight cyclohexyl proto...

Many countries operate regional trapping programs for the detection of exotic tephritid fruit flies, which because of their polyphagous habits pose a serious threat to fruit and vegetable crops. Detection of the Mediterranean fruit fly (medfly), Ceratitis capitata (Wiedemann), relies primarily o...

Reversed-phase high-performance liquid chromatographic methods were developed for the separation of enantiomers of eleven unnatural β2-amino acids on a new chiral stationary phase, using the 11-methylene-unit spacer of aminoundecylsilica gel for the bonding of (+)-(18-crown-6)-2,3,11,12-tetraca...

Both enantiomers of 2-benzylpropanol and 2-benzylpropionic acid have been synthesized using a lipase-catalyzed resolution in an organic solvent and in water.

Cathodically formed 1,4-diacetylbenzene dianion may react as a reducing species toward aromatic halides. It also reacts as an electrogenerated base with the starting product considered as a pronucleophile (source of enolate). The concomitant presence in solution of aromatic radicals and electrog...

The new ligands 1,4-diformylbenzene bishydrazone (DFBH) and 1,4-diacetylbenzene bishydrazone (DABH) have been prepared. DFBH forms complexes with transition metal(II) ions of types MX2(DFBH) (M = Co, Ni, Mn, Zn or Cd, X = Cl; M = Co or Ni, X = SCN; M = Ni, X = Br) and MX2(DFBH)2 (M = Co, Ni, Mn,...

Styrene is one of the most important industrial intermediates consumed in the world and is mainly used as a monomer for reinforced plastics and rubber. Styrene has been found to be hepatotoxic and pneumotoxic in humans and experimental animals. The toxicity of styrene is suggested to be metaboli...