We studied some ionic liquids (ILs) belonging to the pyridinium class under photocatalytic treatment. In particularly, we analysed how the length of the alkyl chain, the kind of inorganic ion and the type of substituents could influence the disappearance rate, the mineralization extent, the acut...

The synthesis and characterization of new kaolinite nanohybrid materials derived from pyridinium based ionic liquids with different functionalities located at the para position are described in this paper. Four ionic liquids (1-(2-hydroxyethyl)-4-methylpyridinium chloride (Mepyr), 1-(2-hydroxyet...

Publisher SummaryThis chapter presents a registry of toxic effects of chemical substances (RTEC). Significant efforts have been made to assemble teratogenic databases with peer-reviewed evaluations. New avenues for the structure–activity relationship (SAR) of teratogenic chemicals studies have ...

A versatile and chemoselective route has been developed for the synthesis of aliphatic fluorinated methyl ethers (ROCH2RF), specifically monofluoromethyl ethers (ROCH2F) and trifluoromethylthiomethyl ethers (ROCH2SCF3), through pyridinium-type salt intermediates derived from methoxymethyl (MOM) ...

Background: Polyphenols appear to have antioxidant activities and may mediate lipid lowering. Methods: Four groups of rats, a high-cholesterol control (HC), HC+lovastatin, HC+3,4-di(OH)-cinnamate, and HC+3,4-di(OH)-hydrocinnamate, were given a semi-synthetic diet. The cinnamate derivative or lov...

Four cholesteryl esters of cinnamic acid derivatives, cholesteryl 2″-hydroxycinnamate, cholesteryl 3″-hydroxycinnamate, cholesteryl 4″-hydroxy-cinnamate and cholesteryl 3″,4″-dihydroxycinnamate, as well as cholestanyl 2″-hydroxycinnamate, which can be used as potential inhibitors of lipids...

The comprehension of the cinnamic derivative phototransformation mechanisms is particularly important when these molecules are used as addressable photosensitive layers. In this work we show that the halo-substituted cinnamate sensitivity to the phototransformation is a function of the excitatio...

Thermal decomposition changes occurring in cholesterol esters of ferulic and sinapic acids were studied by means of TG/DTA. A one-stage decomposition has been established for their thermal degradation in the temperature interval from room temperature to 500°C. The carbon skeleton of the esters ...

Phase transitions of two isomeric derivatives of cholesteryl cinnamate, cholesteryl ferulate(CF) and cholesteryl isoferulate(CI), were studied by means of DSC and TAM(Thermoanalytical Microscopy).CF, cholesteryl 4-hydroxy-3-methoxycinnamate, showed two monotropic mesophases, smectic and choleste...

The cleavage of the N-benzyl bond characterizes the photochemical behaviour of I in methanol. Beside the coupling or the hydrogen abstraction products, the interconvertible 1,4,5,6-tetrahydropyridines VIa and VIb were obtained.

A series of novel 2-(phenylaminocarbonylmethylthio)-6-(2,6-dichlorobenzyl)-pyrimidin-4(3H)-ones have been designed and synthesized. All of the new compounds were evaluated for their anti-HIV activities in MT-4 cells. Most of these new compounds showed moderate to potent activities against wild-t...

3-(2,6-Dichlorobenzyl)-5-methyl-N-nitro-1,3,5-oxadiazinan-4-imine (DNOI) was synthesized and characterized by X-ray diffraction, FT-IR, FT-Raman and UV–Vis spectra. The X-ray diffraction study showed that DNOI has a one dimensional configuration, due to the intermolecular C9H⋯O1 and N4H⋯O2 hydr...

The regioselective benzylic metalation of toluenes using BuLi/KOtBu/TMP(H) (LiNK metalation conditions) and subsequent transmetalation to Si by reaction with TMSCl provides a general one-pot procedure for the synthesis of substituted benzyltrimethylsilanes. ArCH2Si(Me)3 derivatives are bench sta...

This paper contains a combined experimental and theoretical study of vibrational and electronic properties of Benzyl(imino(1H-pyrazol-1-yl)methyl)carbamate (BPMC) molecule. The FT-IR and FT-Raman spectra of the title molecule in solid phase were recorded in the region 4000–400 cm−1 and 4000–50...

A three new series of the ferrocene containing quinolines – 2-ferrocenyl-4-methoxyquinolines, 1-benzyl-2-ferrocenyl-2,3-dihydroquinolin-4(1H)-ones and 1-benzyl-2-ferrocenylquinolin-4(1H)-ones – were synthesized in order to test their in vitro antimicrobial activity against six strains of bacte...

This study comprises the structural and spectroscopic evaluation of a quinoline derivative, 2-chloro-3-methylquinoline (2Cl3MQ), via UV–Vis, 1H and 13C NMR, FT-IR and FT-Raman techniques experimentally, theoretically with DFT and TD-DFT quantum chemical calculations at B3LYP/6–311++G (d, p) le...

Among a variety of lipases tested, that obtained from Candida antarctica (SP 435) induced enantioselective hydrolysis of trifluoroethyl 5,5,5-trifluoro-4-(3′-indolyl)-3-thiapentanoate (1c). The selectivity could be increased by optimizing the reaction conditions. Thus, good selectivity was achi...

As a part of our quest for the synthesis of new bioactive heterocyclic compounds, in our present work we have synthesized a series of 4-(4-(arylamino)-6-(piperidin-1-yl)-1,3,5-triazine-2-ylamino)-N-(pyrimidin-2-yl)benzenesulfonamide (3a–o) derivatives. The newly synthesized compounds were scree...

A series of L-shaped ortho-quinone analogs were designed by analyzing the binding mode with NQO1. Metabolic studies demonstrated that compounds 2m, 2n and 2q exhibited higher metabolic rates than β-lapachone. The docking studies, which supported the rationalization of the metabolic studies, con...

The conformation of side chain –SCH2COOCH3 in title compounds in crystal agrees with the reactivity of these compounds in base catalysed ring closure in solution. In the 2,4-dinitro derivative, the side chain is oriented towards the unsubstituted ortho-position of benzene ring, in the case of t...