Compared with solvent-based resins, waterborne resins still have defects such as insufficient anti-corrosion efficiency. In this paper, the sulfonated graphene/zinc phosphate composites were prepared as an anti-corrosion filler and doped into waterborne polyurethane resin. The morphology of comp...

A new technique for quantifying sphingosine phosphate lyase activity in biological samples is described. In this procedure, 2-hydrazinoquinoline is used to convert (2E)-hexadecenal into the corresponding hydrazone derivative to improve ionization efficiency and selectivity of detection. Combined...

The removal of phosphates, to levels below the detection limit, was achieved over a 30 to 60 min period, depending on the initial phosphate concentration, with Al−Mg anodes in an electrocoagulation cell at 11.0 mA cm−2 with a surface area to volume ratio of 11.7 m−1. The Al−Mg alloy performed we...

A thermally stable esterase from Klebsiella oxytoca is explored as an excellent enantioselective biocatalyst (E > 100) for the hydrolytic resolution of (R,S)-tropic acid esters and (R,S)-ethyl α-methoxyphenyl acetate in biphasic media. An expanded Michaelis–Menten mechanism for the enzymatic a...

The first kinetic resolution of tropic acid ethyl ester (TAEE) with lipase PS and vinyl acetate as an acylating agent is reported. The resulting (S)-(−)-3-acetoxy tropic acid ethyl ester and (R)-(+)-tropic acid ethyl ester are produced in high yields and in excellent ee (87–94%). The method has...

The following porous aluminosilicates were tested as acid catalysts in the reaction of furfuryl alcohol (FA) with ethanol, at 140 °C: micro/mesoporous composite Beta/TUD-1 and the correspondent nanocrystalline (large pore) zeolite H-Beta; ITQ-2 and its zeolite counterpart (medium pore) H-MCM-22...

Efficient iridium-catalyzed decarboxylative annulation reactions between 2-oxo-2-phenylacetic acids and alkyne derivatives has been achieved. [IrCp*Cl2]2 with a (CH3OC6H4)3P ligand, AgSbF6 and Cu(OAc)2 additives was the most efficient catalytic system for this transformation. This reaction is su...

A new series of C-phenyl d-glucitol derivatives was designed and synthesized, and their SGLT1 inhibitory potency and absorbability were evaluated. We also investigated whether kidney drug retention could be avoided by creating molecules with different excretion pathways. To achieve a class of mo...

Rare earth (RE) carboxylates are considered as effective metal-organic precursors (MOPs) for chemical preparation of RE oxide nanomaterials via thermal decomposition. However RE oxocarbonates being the intermediate products of this process require high temperature treatment to be decomposed, tha...

Tryptase is a serine protease found almost exclusively in mast cells. It has trypsin-like specificity, favoring cleavage of substrates with an arginine (or lysine) at the P1 position, and has optimal catalytic activity at neutral pH. Current evidence suggests tryptase β is the most important fo...

A treatment of the ligands, 3-benzyl-substituted 5-(pyridin-2-ylmethylidene)-2-thioxoimidazolidin-4-ones, with Cu(acac)2 in CH2Cl2 affords the mononuclear bis-ligand copper(II) complexes of the corresponding thiohydantoins.

A new organic ligand (4Z,4Z’)-1,1’-[disulfanediylbis(ethane-2,1-diyl)]bis[2-methylthio-4-(pyridin-2-ylmethylidene)-1H-imidazol- 5(4H)-one] chemisorbed on gold electrode surface forms coordination compound with copper(ii), which catalyzes the electrochemical reduction of nitrite in water solution.

In this work, the experimental and theoretical study of new semicarbazone have been reported. The new semicarbazone was synthesized and characterized by FT-IR, FT-Raman and NMR, and the crystal structure was determined by X-ray single-crystal diffraction. The crystallographic asymmetric unit was...

A systematic series of seven mercury compounds of (E)-N-(pyridin-2-ylmethylidene)arylamine (L), where L is a variously R substituted ligand, with the formulations [HgX2L]2: X = Cl; R = 4-CH2CH3 (4), 4-OCH2CH3 (5), 4-Cl (6), 2-CO2CH3 (7), or 4-CO2CH3 (8); X = Br; R = 4-CO2CH3 (9a) and [HgX2L]: X ...

Five mononuclear complexes, i.e. ZnLCl2 (1), [ZnLBr2](CH3CN) (2), ZnLBr2 (3), CdLCl2 (4), and CdLBr2 (5), with L = 2-(methylsulfanyl)-N-(pyridin-2-ylmethylidene)aniline, have been synthesized and characterized. For [ZnLBr2](CH3CN) only a few crystals were obtained from the main batch of ZnLBr2. ...

The Janus kinase (JAK) family of tyrosine kinases has been proven to provide targeted immune modulation. Orally available JAK inhibitors have been used for the treatment of immune-mediated inflammatory diseases, such as rheumatoid arthritis (RA). Here, we report the design, synthesis and biologi...

ROCK1 and ROCK2 are highly homologous isoforms. Accumulated studies indicate that they have distinct different functions, and the development of isoform selective ROCK inhibitors will pave new roads for the treatment of various diseases. In this work, a series of amide-chroman derivatives were s...

The photophysical properties such as singlet absorption, molar absorptivity, fluorescence spectra, fluorescence quantum yield (ϕf) and transition dipole moment (μ12) of 3-(4-dimethylamino-phenyl)-1-{6-[3-(4-dimethylamino-phenyl)-acryloyl]-pyridin-2-yl}-propanone (DMAPAPP) have been studied in d...

Four coordination compounds, that include the discrete binuclear complex [Zn(H2O)4(bda4Py)]2(SO4)2 (1), two isomorphous one-dimensional coordination polymers, {[Zn(NO3)2(bda4Py)2]·2H2O}n (2) and {[Cd(NO3)2(bda4Py)2]·2H2O}n (3), and one two-dimensional coordination polymer {[Cd(bda4Py)2(dpa)2]·...

Three bulky conjugated 4-(2,6-di(pyrazin-2-yl)pyridin-4-yl)benzoate (L)-based coordination polymers (CPs), {[Cu(L)Cl]·2.25H2O}n (1), {[Cu(H2O)(L)](NO3)·H2O}n (2) and {[Zn(H2O)(L)(NO3)][Zn(H2O)2(L)](NO3)H2O}n (3), were solvothermally synthesized by varying transition metal ions and pH values of...