Recently, tetrakis(hydroxymethyl)phosphonium sulfate (THPS) was found to play an important role in the sludge pretreatment process. However, the effects of THPS pretreatment on the characteristics of sewage sludge are still insufficiently understood. The properties of sludge after pretreatment w...
Agricultural production in many emerging economies suffer losses owing to the challenges posed by weeds. Owing to cost, ecological, environmental and other human health safety issues regarding the use and application of chemicals as a control option against invasive weeds, there has been a renew...
Two binuclear Pd (II) and Ir(IV) complexes with new bis [4-hydroxy-6-methyl-3-{(1E)-N-[2-(ethylamino) ethyl] ethanimidoyl}-2H-pyran-2-one] ligand (Schiff base: L) have been prepared and characterized by elemental analysis, ESI-MS, conductivity, NMR (1H NMR, 13C NMR, COSY-NMR, HMBC-NMR and HSQC-N...
Studies on substituted 5H-dibenzo[c,h][1,6]naphthyridin-6-ones and 6H-dibenzo[c,h][2,6]naphthyridin-5-ones have demonstrated that hydrophilic substituents at the 2-position of an ethyl group at the 5- and 6-positions, respectively, can enhance biological activity. The compatibility of such hydro...
The quantitative analysis of a new designer doping agent, 2-ethylamino-1-phenylbutane (EAPB) and its metabolite, 2-amino-1-phenylbutane (APB) in urine samples, and the determination of EAPB in dietary supplement samples, have been presented. The main purpose of the present study was to develop s...
The molecular structure of 2-N-ethylamino-5-methyl-4-nitropyridine (EN5MP) and its vibrational spectra have been analyzed in terms of quantum chemical DFT calculations (B3LYP/6-311++G(d,p) approaches) and related to the XRD data. The EN5MP crystal is triclinic and centrosymmetric and its unit-ce...
Sixteen novel N-(3-carboxyl-9-benzyl-β-carboline-1-yl)ethylamino acids (6a–p) were synthesized as intercalating lead compounds. In the in vitro cytotoxic assay their IC50 values against five human carcinoma cell lines ranged from 10.95 μM to about 400 μM. On S180 mouse model eight of them ex...
The electrochemical behavior of 1-(2-ethylamino)-2-methylimidazoline (imidazoline), its precursor N-[3-(2-amino-ethylamino-ethyl)]-acetamide (amide) and its derivative 1-(2-ethylamino)-2-methylimidazolidine (imidazolidine), is evaluated by using potentiodynamic polarization curves and electroche...
3-Ethylamino-2-(4-nitro-benzoyl)-but-2-enoic acid phenylamide is synthesized, isolated, spectroscopical and structural characterized by means of linear-polarized IR-spectroscopy (IR-LD) of oriented solids as a colloidal suspension in nematic liquid crystal. The experimental IR-band assignment an...
We have designed an efficient, synthetic nucleic acid vector, which is relatively non-toxic. [N-(2-ethylamino)-6-O-glycolchitosan – EAGC] polymers were 10–50 fold less toxic than Lipofectamine 2000, able to complex DNA, mRNA and siRNA into positively charged (zeta potential = + 40 − 50 mV), 50...
In this work, new piperazine containing copolymer membrane was developed from acrylic acid and 2-(2-(piperazin-1-yl)ethylamino)-2-hydroxyethyl methacrylate through free radical polymerization method by means of AIBN as an initiator, in bulk. The monomer feed ratio was varied to obtain various co...
In this paper, a novel β-Oxo thioamide surfactant 3-(ethylamino)-N-phenyl-3-thioxopropanamide (EAPhTXPA) was synthesized and first used as flotation collector for galena and sphalerite. The results of micro-flotation tests showed that EAPhTXPA possessed not only stronger collecting ability but ...
Due to wide variety of biological and pharmacological activities of benzimidazole derivatives, the differences between 2-(2-Chlorophenyl)benzimidazole and 2-(4-Chlorophenyl) benzimidazole were researched by employing terahertz time-domain spectroscopy and density functional theory systematically...
In the present study 2-allyl amino 4-methyl sulfanyl butyric acid (AMSB) was synthesized in good yield. AMSB was characterized by Fourier transforms infrared spectroscopy (FTIR), Nuclear magnetic resonance (NMR) (1H and 13C) and Liquid chromatography mass spectrometry (LCMS). The radical scaveng...
PurposeThe response of 2-amino-4-([14C]methylthio)butyric acid ([14C]Met) uptake and [125I]3-iodo-alpha-methyl-l-tyrosine ([125I]IMT) uptake to radiotherapy of C10 glioma cells was compared to elucidate the intracellular reactions that affect the response of 2-amino-4-([11C]methylthio)butyric ac...
Two new two-dimensional conjugated polymers PBDTT-4S-TT and PBDTT-4S-BDD based on benzo[1,2-b:4,5-b']dithiophene unit with 4-methylthio substituted thiophene side chains were designed and synthesized. The two polymers exhibit slightly blue-shifted absorptions and deeper-lying highest occupi...
PIM kinase family (PIM-1, PIM-2 and PIM-3) is an appealing target for the discovery and development of selective inhibitors, useful in various disease conditions in which these proteins are highly expressed, such as cancer. The significant effort put, in the recent years, towards the development...
It has been reported that aryl/heteroaryl sulfonamide compounds may act as anticancer agents through a variety of mechanisms and the most prominent of these mechanisms is through the inhibition of carbonic anhydrase isozymes. The present work reports the possible utility of 4-(cyclohexenylamino)...
A Selectfluor and base mediated protocol for the synthesis of cyclohexanone ring fused isoxazole derivatives from isoxazoline N-oxides has been successfully developed. This rapid, one-pot, two-step transformation is achieved in acetonitrile, through nitroso intermediate followed by hydration, de...
The series of 2-{2,6-bis[di(4-fluorophenyl)methyl]-4-chlorophenylimino}-3-aryliminobutane derivatives (L1–L5) and their nickel(II) dibromide complexes (Ni1–Ni5) were synthesized, and all organic compounds were fully characterized by the Fourier transform infrared (FT-IR) and nuclear magnetic r...
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