The growing interest in the physical properties of double sulphate crystals is due to the fact that they show anomalous behavior at transition points (M.E.Kassem et.al., 1984). Sodium potassium sulphate is a member of the family of crystals having the general formula M′M″BX4(where M′ stands f...

We investigated the effect of small amounts of ammonium sulfate (NH4)2SO4 on compound fertilizer granulation. We examined the following raw materials: humic acid, ammonium chloride, urea, potassium chloride, and monoammonium phosphate. The mass ratio of organic matter, nitrogen, phosphorus, and ...

The aqueous solubility of the least soluble salts in mixtures of sodium hydrogen succinate, sodium succinate, sodium hydrogen glutarate, and sodium glutarate with and without ammonium sulfate present has been studied. Solubility temperatures were determined in solutions of known concentration us...

Air filters operate in versatile environments, such as different relative humidities (RH), temperatures. Those factors could affect the state of atmospheric hygroscopic salt pollutants, mainly ammonium sulfate and ammonium nitrate. Air filters operation performance can be affected by operation e...

Ammonium nitrate (AN) has proven to be an unstable and hazardous component of mineral fertilizers. In order to analyze the influence of various potassium salts on thermal properties of ammonium nitrate, differential thermal analysis coupled with thermogravimetry and mass spectrometry was used. E...

This study aims to research the relative humidity (RH) effect of the cellulose filter media loading. The filter loading characteristics of test particles under various RHs (15%, 30%, 45%, 60%, and 75%) are evaluated. Besides commonly used potassium chloride particles, ammonium sulfate and ammoni...

Recently we described a novel class of imidazopyridine compounds that showed exceptional anti-RSV potency in cell culture. However, unfavorable pharmacokinetic (PK) properties and glutathione (GSH) adduct liabilities impeded their further development. In a bid to address the PK and early safety ...

In this work the 4,6-dichloro-2-(methylsulfonyl)pyrimidine (DCMSP) has been synthesized from 4,6-dichloro-2-(methylthio)pyrimidine, its molecular and electronic structure was authenticated by detailed spectroscopic signature studies (via SCXRD, FT-Raman, FT-IR and (1H & 13C) NMR), Hirshfeld surf...

The solid-liquid equilibrium for 1-methyl-4-(methylsulfonyl)benzene in nine solvents (methanol, ethanol, acetonitrile, ethyl acetate, acetone, N,N-dimethylformamide, n-butanol, n-propanol, isopropanol) were determined at temperatures from 278.15 K to 318.15 K by using the isothermal saturation m...

5-Amino-4-hydroxyiminopyrazoles and (E)-N1-aryl-3-aryl-4-[(substitutedpyrazolyl)diazenyl]pyrazoles derivatives were conveniently synthesized as the corresponding products by reacting 5-aminopyrazoles with ethyl nitrite or sodium nitrite in ∼10% aqueous HCl solution. All of 5-amino-4-hydroxyimin...

Negative allosteric modulators of metabotropic glutamate receptor 5 (mGlu5) showed efficacy in a number of animal models of different CNS diseases including anxiety and depression. Virtually all of the compounds which reached the clinic belong to the same chemotype having an acetylenic linker th...

Background and objectivesThe objective of this study is to synthesize and evaluate 1-(4-chlorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrobenzylidene) pyrazolidine-3,5-dione (CD59) analogues to establish structure–activity relationship and mechanism of action.

This work described a novel and efficient synthesis of 3-amino-4-cyano-5-phenyl-1H-pyrrole-2-carboxamides. The synthesis was carried out via a simple three-component reaction between arylidenmalononitrile, malononitrile and hydroxylamine hydrochloride in solvent-free conditions. Short reaction t...

A novel class of non-steroidal progesterone receptor antagonists with aromatic β-amino-ketone scaffold have been synthesized and characterized with high binding affinity and great selectivity for the cognate receptors. Among them, compound 22 was shown to be the most potent progesterone recepto...

The development and optimization of a palladium-catalyzed asymmetric conjugate addition of arylboronic acids to cyclic enone conjugate acceptors is described. These reactions employ air-stable and readily-available reagents in an operationally simple and robust transformation that yields β-quat...

The incorporation of a trans-1,2-diaminocyclohexane in place of DPEN provides improvements in enantioselectivity to asymmetric ketone hydrogenation reactions using BrXuPHOS–Ru–diamine catalysts. Substrates containing halogenated aryl rings are particularly compatible with this catalyst, howeve...

Co-entrapment of palladium nanoparticles and soluble [Rh(cod)(μ-Cl)]2 in a silica sol–gel matrix forms a catalyst that promotes exhaustive hydrogenation and hydrogenolysis of various aromatic ketones. While the hydrogenation of acetophenone may proceed by initial formation of α-phenylethanol ...

A series of α-branched α,β-unsaturated ketones were prepared via boron trifluoride etherate mediated reaction between arylalkynes and carboxaldehydes. The evaluation of the antiproliferative activity over hematological (NB4) and solid cancer (A549, MCF-7) cell lines provided a structure-activ...

The synthesis and characterisation of two new Ru(II) catalysts for the asymmetric transfer hydrogenation (ATH) of ketones is described. In the case of 4, the novelty lies in the use of a benzyl tethering group between the asymmetric ligand part (TsDPEN) and the η6-arene ring, which increases th...

A series of ketones underwent an allylation reaction using diallyldibutyltin in the presence of a catalytic amount of In(OTf)3. The method was found to be superior to most of the known methods. Thus, a new allyltin reagent Bu2Sn(allyl)2/In(OTf)3 for ketones was developed.