The 13C NMR spectra of several 1,3-pyridylmethyl ureas and their corresponding thioureas have been obtained. The 13C chemical shifts, and the direct and long range 13C1H coupling constants have been deduced. The results indicate an E, Z molecular conformation for 1,3-pyridylmethyl ureas and th...

A cell line in which RD-HGA16 cells were stably transfected with the hTAAR 1 receptor was created and utilized to carry out a systematic evaluation of a series of β-phenethylamines. Fair agreement was observed with data obtained for aryl and ethylene chain substituted analogs in an AV12-664 cel...

A number of chiral 1-arylethylamines and 1-alkylethylamines were resolved with the 3-carboxy-2-naphthoate of isopropylidene glycerol 2, previously reported to be an even more efficient resolving agent for 1-phenylethylamine than the corresponding hemiphthalate 1. The results obtained for the 1-a...

N-[2-(4-iodophenyl)ethyl]-N-methyl-2-(1-piperidinyl)ethylamine, IPEMP, and the corresponding bromo derivative, BrPEMP, have been synthesized and characterized. Both BrPEMP and IPEMP were evaluated for sigma-1 and sigma-2 subtype receptor affinities and found to possess very high affinities for b...

The Ullmann coupling of (S)-[1-(3-bromophenyl)-ethyl]-ethylamine (1) with a variety of N–H heteroarenes using microwave heating is described.

An efficient biocatalytic process has been developed for the resolution of 1-(3′-bromophenyl)ethylamine (RS)-1 by way of enantioselective lipase-mediated (R)-selective acylation with ethyl 2-methoxyacetate to afford (S)-amine (S)-1 and (R)-2″-methoxyacetamide ((R)-2) in 91–95% and 90–92% iso...

Reaction of ferrocenecarbothioamide and N-(ethoxycarbonyl)ferrocenecarbothioamide with alkyl (mainly benzyl) halides in the presence of K2CO3 has been studied. The former compound yielded cyanoferrocene in high yield whereas the latter was transformed into the corresponding thioimidates as a res...

The reaction of ethyl 3-(o-trifluoroacetamidoaryl)-1-propargylic esters with ethyl iodoacetate or α-bromoacetophenone in the presence of K2CO3 in DMSO provides a new simple access to 2-acyl- and 2-ethoxycarbonyl-3-alkenyl indoles.

Tetrakis(alkoxycarbonyl)porphyrin and its β-octafluoro-substituted derivatives were synthesized via Lindsey method and transformed to their zinc complexes. Single crystal X-ray structures of corresponding Zn(II) porphyrins revealed that β-octafluorination will give more compactness of porphyri...

The title compound has been synthesized in the reaction of ferrocene with ethoxycarbonyl isocyanate in methanesulfonic acid. It has been found that it undergoes N-alkylation with benzyl alcohols under classical Mitsunobu conditions (PPh3/DEAD). However, in the reaction with cholesterol and stigm...

Single mineral flotation of chalcopyrite, molybdenite and pyrite with a regular collector (potassium amyl xanthate) and a selective collector (N-isopropoxypropyl-N′-ethoxycarbonyl thiourea) for chalcopyrite in both de-ionized water and synthetic sea water were investigated in this study. The re...

For the first time, a very simple, efficient, mild, catalytic, and one-step procedure for the synthesis of a series of new 3-ethoxycarbonyl-3-indolylsubstituted-isoindol-1-one derivatives has been achieved via a Friedel–Crafts alkylation of indoles with 3-hydroxy-3-ethoxycarbonylisoindolin-1-on...

The crystal structure of silver(II) 5,10,15,20-tetra(ethoxycarbonyl)porphyrin (Ag[II]TECP) revealed it formed a one-dimensional coordination polymer through weak Ag–O interactions with an unusual six-coordinated central silver(II) atom.

This review describes synthetic methods for the preparation of such modern and versatile building-blocks as 2-CF3-4-pyrones (2-(trifluoromethyl)-4H-pyran-4-ones), and their use in regioselective syntheses of various CF3-containing compounds. Synthesis of 2-CF3-4-pyrones bearing a substituent (su...

The behaviour of different types of native starch (regular, waxy, and high-amylose maize starch) and modified starch (acetylated/adipate maize starch with regular basis and hydroxypropylated/phosphate maize starch with waxy basis) in mixtures with calcium caseinate (CN) and embedded in casein ma...

Starch was commonly used to improve the stability of set yogurt. In this research, casein and modified starches were placed in a simulated yoghurt system giving the advantage of a low variation in the environment parameters compared to a natural yoghurt system. The interactions between modified ...

Effects of adlay starch on the rheological and conformational changes in wheat gluten gel were investigated in this study. Rheological measurement showed that adlay starch-gluten composite gels exhibited higher storage modulus G′ and loss modulus G″ compared with pure gluten gels. This result ...

Structural changes of chemically modified rice starch (CMRS) by one-step reactive extrusion (REX) via esterification, acetylation, hydroxypropylation, and cross-linking or dual-modification (hydroxypropylation-cross-linking and acetylation-cross-linking) were investigated. REX treatments exhibit...

The hydroxypropyl distarch phosphate (HPDSP) was added to set yoghurt system as stabilizer in present work. Herein, the interaction between casein and HPDSP was researched. During the course of the study, casein and modified starch were placed in a simulation yoghurt environment in order to faci...

The distributions of phosphorus and hydroxypropyl groups within granules of cross-linked and hydroxypropylated sweet potato starches were investigated. Chemical surface peeling of starch granules was performed after sieving of native and modified starches into large-size (diameter ≥ 20 μm) and...