Publisher SummaryThis chapter lists the important subjects on organic synthesis that are discussed in the publication Studies in Natural Products Chemistry, Volumes 1–30, such as abietic acid, Abramov reaction, acid-labile protecting groups, sugar aglycone linkage, sulfoxides, Swern oxidation, ...

Nanomedicine has made great progress toward the diagnosis and treatment of diseases by exploiting physicochemical properties and biological interactions of nanomaterials that differ from the corresponding conventional materials. In the past decade, the advancement of biocompatible and biodegrada...

Near-infrared (NIR) fluorescent sensors have been actively pursued due to organisms exhibiting little autofluorescence in near-infrared regions. Capable of emitting luminesence under 980 nm excitation, upconversion nanoparticles have shown promise as optical agents for in vivo bioimaging. Based ...

The development of photocatalysts responsive towards a broader region of the solar (UV-to-NIR) light is important for efficient harvesting of sunlight for photochemical and photoelectrical applications. In this study, two photocatalytic systems (BV/LEDs and BV/UCPs where UCPs stands for NaYbF4:T...

Grated Parmigiano–Reggiano cheese holds a valuable market segment and its quality strictly depends on the amount of rind, size, shape of cheese particles and original cheese properties. Textural properties of the rind and inner part of the cheese significantly affect size and shape of grated pa...

Hazardous chemicals excruciatingly contaminated water, air, and soil for the past few decades. Eco-friendly techniques to clean and or destroy these harmful chemicals is an urgent requirement at this moment. In this direction, a large number of methodologies had been suggested to eliminate the a...

Total polyphenols (TP), caffeine, and free amino acids (FAA) constitute tea taste. The feasibility of developing a cross-category model for predicting TP, caffeine and FAA contents in Chinese black, dark, oolong, and green teas, was investigated. Diffuse reflectance spectra (4000–10,000 cm−1) o...

The increasing desire to control quality in foods in real-time (e.g. on-line, at line, market) demands the development of innovative and easy to use analytical systems [e.g. a combination of sensors with multivariate data analysis (MVA)]. It has been long established that the ability to analyse ...

Seasonal variations and land use responses of nirS-type denitrifying bacterial communities were investigated in a cultivated black soil (0–20 cm) in Northeast China with different fertilization treatments [no fertilizer (NoF), chemical fertilizer (CF) and CF plus manure (CFM)] and in a neighbou...

In this study, we evaluate the use of visible-near infrared (vis-NIR) and portable X-ray fluorescence (pXRF) for delineating soil horizons and how these are affected by soil moisture in a Mollisol (A, Ab, 2E, and 2Bt) profile of south-central Wisconsin. The soil profile was scanned in the field ...

The development of benzothiazine-1,1-dioxide derivatives as a new structural class of potent endothelin receptor antagonists is described. Structure–activity relationships (SAR) revealed that PD164800 (1) is a potent antagonist of the ETA receptor subtype.

The structural aspects of the complexes formed by thiosemicarbazones (TSCs) and semicarbazones (SCs) with the metallic elements of Groups 12, 13, 14 and 15 are surveyed up to 1998. Descriptions of 71 structures containing neutral or deprotonated TSCs and ten with SCs include information on the m...

The partial reduction of carboxylic acids and their derivatives to aldehydes is a nontrivial exercise in synthetic chemistry with a large number of methods existing to achieve this transformation. The purpose of this chapter is to give the reader an overview of these methods by subdividing the c...

Publisher SummaryThis chapter describes the methods of synthesis of pyrroles and n-vinylpyrroles, their reactions, and their physicochemical and quantum chemical studies. The significant attention given to pyrroles is, mainly, due to the fact that the pyrrole nucleus is the structural unit of ma...

This review provides comprehensive coverage of larger [m]pyridine[n]pyrrole oligomeric (m + n > 3) chains or [m]pyridine[n]pyrrole (m + n ≥ 3) macrocycles with at least three directly linked heterocyclic rings, their syntheses and the complexes they form with anions, guest molecules and metal c...

Aimed at discovering effective EGFR inhibitors, six series of quinazoline derivatives bearing a semicarbazone moiety were designed, synthesized and evaluated in different cancer cell lines (A549, HepG2, MCF-7 and PC-3). Most of the selected compounds showed remarkable cytotoxicity with IC50 valu...

Components of colophony (rosin) resin acids are sensitizers through dermal and pulmonary exposure to heated and unheated material. Significant work in the literature identifies specific resin acids and their oxidation products as sensitizers. Pulmonary exposure to colophony sensitizers has been ...

To understand the skin sensitization mechanism of 15-hydroperoxyabietic acid, the major allergen in colophony, we first examined the formation of potential reactive radicals derived from its reaction with light, heat and TPP-Fe3+. Trapping with 1,1,3,3-tetramethylisoindolin-2-yloxyl nitroxide co...

Isatin-conjugated 3H-indole-N-oxides were synthesized from isatin-derived propargylic alcohols and nitrosobenzenes in moderate yields. Isatin-conjugated 3H-indole-N-oxides were converted to novel spiroindolenines under PPh3-mediated deoxygenation reaction condition, serendipitously.

Five new koumine-type alkaloids (1–5) along with six known ones were isolated from the roots of Gelsemium elegans. Their structures with absolute configurations were elucidated on the basis of NMR spectroscopy and electronic circular dichroism spectral analyses. The inhibitory effects of compou...