Treatment of AgNO3 with one equiv. of N,N′-bis(acetylacetone)-1R,2R-diaminocyclohexane (L) afforded a mononuclear complex [Ag(η2-L)NO3] (1) in which the central silver(I) atom adopts a distorted trigonal planar geometry by coordinating two carbon atoms of the methane moieties of the ligand and...

Irradiation of 5-fluorouracil (1) and 5-fluoro-2′-deoxyuridine (2) with Nα-acetyl-L-tryptophan N-ethylamide (5) in aqueous buffered (pH 7) solutions led to Nα-acetyl-2-(uracil-5-yl) tryptophan N-ethylamide (6) and Nα-acetyl-2-[l-(2-deoxy-β-l) erythro-pentofuranosyl)uracil-5-yl] tryptophan N...

Phosphodiesterase type 4D (PDE4D) has been indicated as a promising target for treating neurodegenerative pathologies such as Alzheimer's Disease (AD). By preventing cAMP hydrolysis, PDE4 inhibitors (PDE4Is) increase the cAMP response element-binding protein (CREB) phosphorylation, synaptic...

Pharmaceutical cocrystals are multicomponent materials containing an active pharmaceutical ingredient with another component in well‐defined stoichiometry within the same unit cell. Such cocrystals are important in drug design, particularly for improving physicochemical properties such as solub...

Chiral resolution of native dl-tartaric acid was performed by ligand-exchange capillary electrophoresis using copper(II)–d-quinic acid as a chiral selector. Factors affecting chiral resolution, migration time, and peak area of tartaric acid were studied. The running conditions for optimum separ...

Colloidal borosilicate and boron-modified colloidal silica sols were studied by 11B NMR. Formation of B–O–Si chemical bonds is established in both materials. It is shown that boron present in colloidal borosilicate is stable towards the action of complexing agents catechol and tartaric acid. I...

A urea-(DL)tartaric acid single crystal has been prepared for the first time as a SHG material. It is in a monoclinic system with space group P21. The linear properties and relative effective nonlinear coefficient are presented in this paper.

A simple and practical synthesis of (R)-(−)-muscone was achieved by optical resolution of dl-muscone using tartaric acid derivatives. The acetalization of dl-muscone with N,N′-dibenzyl-l-tartaramide in the presence of Sc(OTf)3 and methyl orthoformate furnished a diastereomeric mixture of acetal...

The terahertz (THz) absorption spectra of l-, d-, and dl-tartaric acid have been measured in the frequency range from 0.2 to 2.0 THz by terahertz time-domain spectroscopy (THz-TDS). The characteristic absorption peaks of these three tartaric acid isomers were obtained, which showed remarkable di...

In this letter, we report the roles of acid in governing the one-dimensional polyaniline (PANI) nanostructures formation during an interfacial oxidation polymerization using ammonium peroxydisulfate (APS) as oxidant and dl-tartaric acid (TA) as dopant. Results showed that in the absence of TA or...

The terahertz (THz) absorbance spectra of two tartaric acid isomers (D- and DL-tartaric acid) were determined using terahertz time-domain spectroscopy (THz-TDS) in the range of 0.2–2.0 THz. Significant differences between D- and DL-tartaric acid have been found in their THz characteristic absor...

BackgroundAtrial fibrillation (AF) increases the risk of thromboembolism. Atrial cardiopathy, defined as structural left atrial enlargement (LAE), has been proposed to be a unifying risk factor for stroke, with or without atrial fibrillation (AF). We sought to understand the relative importance ...

ObjectivePostoperative atrial fibrillation (POAF) is common after anatomic thoracic surgery. Elevated preoperative brain natriuretic peptide (BNP) level is strongly associated with risk of POAF. We describe the development and internal validation of a clinical prediction model for POAF that incl...

Measurement of cardiac natriuretic peptides in plasma has gained a diagnostic role in the assessment of heart failure. Plasma measurement is though hampered by the marked instability of the hormones, which has led to the development of analyses that target N-terminal fragments from the prohormon...

Before birth, the ability of the organism to conserve salt and water is not critical as the placenta controls fluid balance in the fetus. The event of birth prompts abrupt changes in the infant's environment, rendering the newborn responsible for maintaining fluid and electrolyte homeostasi...

IntroductionThe impact of atrial natriuretic peptide (ANP) value for predicting paroxysmal atrial fibrillation (pAF) in ischemic stroke patients remains uncertain.

IntroductionNatriuretic peptides (NPs) play a pivotal role in maintaining fetal circulation; however, little is known about their metabolism. The aim of the present study was to elucidate the metabolism of plasma NPs in the fetoplacental circulation.

Increasing evidence shows that the endoplasmic reticulum (ER) stress is an early event that injures pancreatic acinar cells and contributes to the pathogenesis of acute pancreatitis. In the present work we sought to establish whether atrial natriuretic peptide (ANP) alleviated ER stress in rats ...

BackgroundAtrial fibrillation (AF) is the leading cause of cardioembolic stroke (CES), and patients with stroke and AF are frequently assumed to have CES. However, strokes presumably due to atherosclerotic pathophysiologies in large or small vessels can also occur in patients with AF. The aims o...

PurposeAcute kidney injury (AKI) is common in the intensive care unit (ICU). Selected clinical studies have implied human atrial natriuretic peptide (hANP) improves renal function; however, the treatment effects for AKI are unclear.